Inflammation  >>  tenofovir disoproxil fumarate  >>  Phase 1
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12 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
tenofovir disoproxil fumarate / Generic mfg.
NCT02908191: A Study in Healthy Volunteers and Patients With Chronic Hepatitis B

Completed
1a/1b
86
RoW
ABI-H0731, Placebo for ABI-H0731, Sugar pill manufactured to mimic the ABI-H0731 tablet, Entecavir, Tenofovir disoproxil fumarate, Pegasys, peginterferon alfa-2a, Nucleos(t)ide
Assembly Biosciences
Chronic Hepatitis B
03/18
06/18
NCT01671787: A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis B

Completed
1b
51
Canada, US, Europe, RoW
GS-7340, Tenofovir disoproxil fumarate, Viread
Gilead Sciences
Chronic Hepatitis B
04/13
04/13
NCT00828789: VX-950-TiDP24-C134: Drug-drug Interaction Trial Between Combination of Efavirenz and Tenofovir Disoproxil Fumarate and Different Dosages of Telaprevir on Healthy Volunteer

Completed
1
20
RoW
Efavirenz; Tenofovir disoproxil fumarate; Telaprevir
Tibotec BVBA
Hepatitis C, HCV, HIV, AIDS
04/09
04/09
NCT01205139: TMC435-TiDP16-C114 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents TMC278 and Tenofovir

Completed
1
48
Europe
TMC435, TDF, TMC435 + TDF, TMC435 + TMC278, TMC278
Tibotec Pharmaceuticals, Ireland
Hepatitis C Virus
03/11
03/11
NCT01480622: Pharmacokinetic (PK) Profiles of Tenofovir Disoproxil Fumarate (TDF) 300 mg in Healthy Chinese Subjects

Completed
1
14
RoW
TDF tablets
GlaxoSmithKline
Hepatitis B, Chronic
12/11
12/11
NCT02589457: Study to Compare the Safety and Pharmacokinetics of CKD-390 Tablet With Viread® Tablet

Completed
1
40
RoW
CKD-390, Viread® tablet
Chong Kun Dang Pharmaceutical
Chronic Hepatitis B
12/15
12/15
NCT02920931: A Randomized, Open-label, Single-dosing, 2X2 Crossover Study to Compare the Safety and Pharmacokinetics of BR-TND Tablet(Tenofovir Disoproxil) With Viread Tablet(Tenofovir Disoproxil Fumarate) in Healthy Male Volunteers

Completed
1
50
RoW
Tenofovir disoproxil
Boryung Pharmaceutical Co., Ltd
Hepatitis
04/16
04/16
NCT03032536: Study of the Relative Oral Bioavailability of AL-3778 Tablets and Drug Interaction With Entecavir or Tenofovir Disoproxil Fumarate in Healthy Volunteers

Terminated
1
54
RoW
AL-3778, NVR 3-778, JNJ-63595948, ALS-003778, Entecavir, Tenofovir disoproxil fumarate, Viread
Alios Biopharma Inc.
Hepatitis B, Chronic Hepatitis B, Viral Hepatitis B
06/17
06/17
NCT03662568: A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjects

Completed
1
56
RoW
GLS4, Morphothiadine Mesilate Capsules, RTV, Ritonavir tablet, ETV, Entecavir table, TDF, Tenofovir Disoproxil Fumarate table
Sunshine Lake Pharma Co., Ltd.
Chronic Hepatitis B
07/18
06/19
NCT03596697: A Study in Healthy Volunteers

Completed
1
92
US
CRV431, Placebo, TDF
Hepion Pharmaceuticals, Inc.
Hepatitis B, Infectious Disease, Liver Diseases
09/20
06/21
OSPREY, NCT05123599: A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection

Active, not recruiting
1
24
Europe, RoW
JNJ-73763989, JNJ-3989, JNJ-64300535, JNJ-0535, ETV monohydrate, Tenofovir disoproxil, TAF
Janssen Research & Development, LLC
Hepatitis B, Chronic
07/23
08/24
SALMONS, NCT05550519: A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment

Withdrawn
1
0
Europe
Entecavir (ETV), Tenofovir Disoproxil Fumarate (TDF), Tenofovir Alafenamide (TAF)
Janssen Pharmaceutica N.V., Belgium
Hepatitis B, Chronic
08/25
08/25

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