Hepadnaviridae Infections  >>  tenofovir disoproxil fumarate  >>  Phase 3
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10 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
tenofovir disoproxil fumarate / Generic mfg.
NCT00117676 / 2004-005119-27: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B

Completed
3
382
US, Canada, Europe, RoW
TDF, Viread®, ADV, Hepsera®, TDF placebo, ADV placebo, FTC/TDF, Truvada®
Gilead Sciences
Chronic Hepatitis B
04/07
01/16
NCT00116805 / 2004-005120-41: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis B

Completed
3
266
US, Canada, Europe, RoW
TDF, Viread®, ADV, Hepsera®, TDF placebo, ADV placebo, FTC/TDF, Truvada®
Gilead Sciences
Chronic Hepatitis B
05/07
01/16
NCT00805675: Effects of Telbivudine and Tenofovir Disoproxil Fumarate Treatment on the Hepatitis B Virus DNA Kinetics in CHB

Completed
3
83
RoW
Telbivudine, Tenofovir, Telbivudine plus tenofovir
Novartis Pharmaceuticals
Hepatitis B Virus
12/10
 
DEFINE, NCT00410202: Entecavir Plus Adefovir Combination Therapy Versus Entecavir Monotherapy vs Therapy With Adefovir Plus Lamivudine for Chronic Hepatitis B Infected Subjects With Lamivudine-resistant Virus

Completed
3
629
US, Canada, Europe, RoW
Entecavir, Baraclude, BMS-200475, Tenofovir, Viread, Adefovir, Hepsera, Lamivudine, Epivir
Bristol-Myers Squibb
Hepatitis B, Chronic
01/11
07/12
NCT00734162 / 2007-003704-35: Evaluation of Tenofovir Disoproxil Fumarate in Adolescents With Chronic Hepatitis B Infection

Completed
3
106
US, Europe, RoW
Tenofovir disoproxil fumarate (TDF), Viread®, Placebo
Gilead Sciences
Hepatitis B Virus (HBV)
03/11
12/15
NCT01300234: Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) 300mg in Chinese Subjects With Chronic Hepatitis B (CHB)

Completed
3
512
RoW
Tenofovir disoproxil fumarate (TDF) tablets, TDF tablet, Adefovir dipivoxil (ADV) tablets, ADV tablet
GlaxoSmithKline
Hepatitis B
10/12
12/16
NCT01063036 / 2009-015705-40: Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous Treatment

Completed
3
144
Europe
Entecavir, Baraclude®, BMS-200475, Tenofovir, Viread®
Bristol-Myers Squibb
Chronic Hepatitis B
11/12
02/14
NCT01480284: Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B Untreated With Nucleic Acid Analogue

Completed
3
166
Japan
GSK548470 300 mg tablet, GSK548470, ETV 0.5 mg capsule, ETV
GlaxoSmithKline
Hepatitis B, Chronic
01/13
11/14
NCT01475851: Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other Drugs

Completed
3
34
Japan
GSK548470 300 mg tablet, GSK548470
GlaxoSmithKline
Hepatitis B, Chronic
06/13
10/14
NCT01872988: Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinoma

Terminated
3
320
RoW
Tenofovir, Viread, Placebo
Taichung Veterans General Hospital, Gilead Sciences, Taipei Institute of Pathology
Chronic Hepatitis B, Hepatocellular Carcinoma
02/18
02/18

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