Infertility  >>  Phase 1
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56 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Infertility
ACTRN12613001316796: Endometrial preparation for cryo embryo transfer: effect of Gonadotropin Releasing Hormone Agonists (GnRHa) coupled with oestrogen and progesterone on hormonal profile and pregnancy rate

Not yet recruiting
1
140
 
Elshatby University Maternity Hospital Department of Obstetrics and Gynecology, Elshatby University Maternity Hospital Department of Obstetrics and Gynecology
Infertility
 
 
ACTRN12610000064000: A prospective Randomised Controlled Trial assessing recombinant Luteinising Hormone supplementation in patients with a relative reduction in Luteinising Hormone (LH) levels during Vitro Fertilisation/Intracytoplasmic sperm Injection (IVF/ICSI) treatment.

Recruiting
1
697
 
IVFAustralia, IVFAustralia
Infertility treated with IVF, Low serum LH levels during IVF treatment cycles.
 
 
ChiCTR-ONRC-14005128: The clinical outcome of different types of progesterone used for ovarian stimulation in normalovulatory women

Recruiting
1
360
 
MPA 10mg/d ;P 200mg/d ;dydrogesterone 20mg/d
Shanghai Ninth People's Hospital; Shanghai Ninth People's Hospital, National nature science foundation of China
infertility
 
 
ChiCTR-OPN-14005276: the clinical outcome of HMG, HP-HMG, u-FSH and MPA used for ovarian stimulation in normalovulatory women

Recruiting
1
180
 
HMG and MPA ;HP-HMG and MPA ;u-FSH and MPA
Shanghai Ninth People's Hospital; Level of the institution:, National nature science foundation of China
infertility
 
 
ChiCTR-IPC-14005419: The effectiveness of endometrial injury in different phase of menstrual cycle: a prospective controlled clinical study

Not yet recruiting
1
400
 
lendometrial injury in luteal phase ;lendometrial injury in menstrual period ;lendometrial injury in luteal phase ;lendometrial injury in menstrual period
First Affilited Hospital of Zhengzhou Univercity; Level of the institution:, MerckSerono China Research Fund for Fertility Experts
Female Infertility
 
 
ChiCTR1800014443: A study to compare the endometrial features of women who did and did not benefit from endometrial scratch in the cycle preceding frozen embryo transfer

Not yet recruiting
1
120
 
Luteinization Hormone (LH) surge + 7 days
Prince of Wales Hospital, The Chinese University of Hong Kong; Level of the institution:, N/A
infertility
 
 
ChiCTR1900021049: Validation of a Fertility Status Awareness Tool (FertiSTAT) to Access the Fertility Problem among Hong Kong Chinese

Recruiting
1
250
 
Nil
Department of O&G, Prince of Wales Hospital, Chinese University of Hong Kong; Level of the institution:, Nil
Pregnant and infertile women
 
 
ChiCTR-ONRC-12001858: The different pretreatment before the GnRH antagonist protocol in the application of in vitro fertilization and embryo transfer

Completed
1
319
 
used short acting GnRH agonist before GnRH antagonist treatment ;used short-acting oral contraceptives before GnRH antagonist treatment ;that untreated before GnRH antagonist treatment
Shenzhen Hospital of Peking University; Shenzhen Hospital of Peking University, self
infertility
 
 
ChiCTR1800018075: The effects of ET catheter depth on the pregnency outcome of in vitro fertilization and embryo transfer: a prospective randomized trial

Recruiting
1
250
 
The ET catheter depth in the uterin cavity is 10mm ;The ET catheter depth in the uterin cavity is 20mm
Department of Gynecology & Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Department of Gynecology & Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Department of Gynecology & Obstetrics,Sun Yat-sen Memorial Hospital
Infertility
 
 
ChiCTR-CPC-14005382: Research on expression of SPAG9 and anti-SPAG9 autoantibody in peripheral blood with testicular fine needle aspiration

Recruiting
1
50
 
Testis puncture
Jun-ping Xing; None, The tutor subject
Male infertility
 
 
ChiCTR-IPR-14005293: The influence of initiation of progesterone supplementation in IVF-ET outcome-a prospective, randomized, controlled trial.

Not yet recruiting
1
200
 
initiation of progesterone one day after oocyte re
Reproductive Center, First Affiliated Hospital, SUN Yat- sen University, Guangzhou; SUN Yat- sen University, Medical Scientific Research Funds of Guangdong Province (B2012091)
infertility
 
 
ChiCTR-IPC-14005535: The infulunce of TEAS for patients undergoing IVF-ET aspect of ovarian response and pregnancy outcome

Not yet recruiting
1
300
 
2Hz TEAS ;2Hz TEAS ;2Hz TEAS ;2Hz TEAS ;2Hz TEAS ;2Hz TEAS
Department of Obstetrics and Gynecology, Reproductive Medical Center, Peking University Third Hospital; Peking University Third Hospital, TEAS in reproductive medicine application, the Ministry of health industry project (201302013)
infertility
 
 
ChiCTR-IPR-14005580: The relationship between Metabolic enzyme gene polymorphism and idiopathic male infertility

Not yet recruiting
1
600
 
testosterone undecanoate+tamoxifen+ vitamin C+ vitamin E + coenzyme Q10 ;testosterone undecanoate+tamoxifen ;Placebo
Affiliated Hospital of Guiyang Medical College; Affiliated Hospital of Guiyang Medical College, The National Natural Science Fund
Male Infertility
 
 
ChiCTR-OPC-14005553: Clinical study of the treatment of infertility caused by severe intrauterine adhesions by collagen scaffold loaded with umbilical cord blood-derived mesenchymal stem cells

Completed
1
20
 
hysteroscopy adhesiolysis followed by collagen scaffold loaded with umbilical cord blood-derived mesenchymal stem cells treatment
The Affiliated Drum Tower Hospital of Nanjing University Medical School; The Affiliated Drum Tower Hospital of Nanjing University Medical School, Strategic Priority Research Program of Chinese Academy of Science
infertility caused by severe intrauterine adhesions
 
 
ChiCTR-IPR-15007251: The clinical outcome of MPA and Duphaston in Primed-progesterone ovarian stimulation protocol for normalovulatory undergoing IVF cycle

Not yet recruiting
1
200
 
HMG AND MPA ;HMG AND Duphaston
Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine; Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Three-year Plan on Promoting TCM Development Funds and Shanghai Science and Technology Development Funds
infertility
 
 
ChiCTR-IPR-15006369: The improvement of endometrial receptivity in PCOS patients by Vitamin D3: a prospective randomized controlled clinical trial

Not yet recruiting
1
420
 
Placebo for three months ;Vitamin D3 for three months ;Placebo for three months ;Vitamin D3 for three months
First Affilited Hospital of Zhengzhou Univercity; First Affilited Hospital of Zhengzhou Univercity, MerckSerono China Research Fund for Fertility Experts
Female Infertility
 
 
NCT03634644: Omega-3 PUFA for Treatment of Patients With Idiopathic Oligoasthenoteratospermia

Recruiting
1
30
RoW
Omega 3 fatty acid, Placebo Capsule, Placebo oral capsule
Jinling Hospital, China
Male Infertility Due to Hypospermatogenesis
03/19
10/22
ChiCTR-RIC-15007585: Role of miRNA and its mechanism to uterine peristalsis

Not yet recruiting
1
30
 
Endometrium biopsy
Xiangya Hospital, Central-south University; Xiangya Hospital, Central-south University, None
Infertility
 
 
NCT04541459: Validation of New Devices Against Ambient Electromagnetic Radiation

Recruiting
1
40
US
new device against ambient electromagnetic radiation, sham device against ambient electromagnetic radiation
Waveguard GmbH
Male Infertility
03/21
04/21
NCT04676269: Amnion Bilayer and Stem Cell Combination Therapy on Thin Endometrium Infertile Patients

Recruiting
1
40
RoW
Amnion only, Amnion - endometrium cells, Amnion - amnion epithelial cells, Amnion-EnSC-AESC
Indonesia University
Cell- and Tissue-Based Therapy
07/21
12/21
NCT04361175: Cost Effectiveness Analysis for Induction of Ovulation in the Polycystic Ovary Syndrome by Letrozole Versus Clomiphene Citrate

Not yet recruiting
1
212
NA
Letrozole, Clomiphine Citrate
Assiut University
Infertility
09/21
12/21
ChiCTR2000039182: Comparison of endometrial receptivity between fresh and frozen–thawed embryo transfer after GnRH-antagonist protocol: a randomized controlled trial

Recruiting
1
820
 
fresh embryo transfer ;frozen–thawed embryo transfer
The First People Hospital of Yunnan; The First People Hospital of Yunnan, Reproductive genetic disease clinical medical center in Yunnan Province
infertility
 
 
NCT02912104: A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Failure

Completed
1
36
RoW
human amniotic epithelial cells (hAECs) transplantation, hAECs transplantation
International Peace Maternity and Child Health Hospital, Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China
Primary Ovarian Insufficiency, Premature Ovarian Failure, Infertility
01/22
01/23
PTX-Zn, NCT05178953: The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia

Recruiting
1
160
RoW
Zinc Sulfate 220 mg Capsules, zinc, Pentoxifylline, Trental
Arak University of Medical Sciences
Men Infertility
01/22
01/22
ChiCTR2100050198: A randomized controlled trial on the effect of different COS protocols in IVF

Recruiting
1
500
 
new trigger protocol ;HCG trigger ;HCG+Gnah ;Gnah ;a novel protocol
Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine; Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine, Key Research and Development Projects of JiangXi Province
Infertility
 
 
NCT04878705: Safety and Tolerability of TWP-201 in Healthy Female Subjects

Recruiting
1
48
RoW
TWP-201, placebo
Shandong TheraWisdom Biopharma Co., Ltd.
Infertility
10/22
12/22
ChiCTR2200060212: Application of immersive VR technology in improving the outcome of assisted reproduction

Recruiting
1
240
 
Wear VR equipment one day before operation and watch 3D video of oocyte retrieval operation ;Wear VR equipment and watch videos during operation ;After operation, wear VR equipment, watch videos or play games ;routine care
Women and Children’s Hospital of Chongqing Medical University; Women and Children’s Hospital of Chongqing Medical University, Chongqing Municipal Health Commission Project
infertility
 
 
PCOS, NCT04987632: Effect of Acupuncture Plus Governor Vessel Moxibustion Combined With Letrozole on Live Birth in Anovulatory Infertile Women With Spleen-kidney Yang Deficiency

Not yet recruiting
1
90
NA
Letrozole, acupuncture, Governor vessel moxibustion
Qiu-ping Lin
PCOS, Infertility, Female
12/22
12/22
ChiCTR2200057987: To explore the effect of Zishen Quyu Jiedu Recipe on the outcome of IVF-ET in patients with endometriosis of kidney deficiency and blood stasis type based on Wnt signal pathway

Not yet recruiting
1
99
 
Shishen Quyu detoxifying granules ;Placebo ;Placebo
Affiliated Hospital of Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Chinese Medicine, A Chinese Medical Syndrome Study of infertility due to phlegm dampness type PCOS based on follicular fluid proteomics
Endometriosis
 
 
NCT05390606: Effects of Flourish HEC and BioGenesis to Improve Conception

Terminated
1
1
US
Flourish HEC and BioGenesis
Vaginal Biome Science, Dr. Aimee Eyvazzadeh, Inc.
Infertility, Infertility Unexplained
03/23
03/23
ChiCTR2200062915: Study on improving oocyte quality of infertile patients with phlegm-dampness PCOS by electroacupuncture

Not yet recruiting
1
70
 
Electropuncture ;None
Affiliated Hospital of Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Natural Science Foundation of Shandong Province
PCOS
 
 
ACTRN12619001593123: ELONVA FLARE PROTOCOL: a new approach for poor responders in superovulation for In Vitro Fertilisation (IVF).

Completed
1
20
 
UNSW, Merck, Sharp and Dohme
Infertility
 
 
infertility, NCT06342856: Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia

Recruiting
1
120
RoW
co enzyme Q10 , L- Carnitine
Ain Shams University
Infertility Unexplained, Oligospermia
06/24
07/24
ChiCTR2200057985: Effect of percutaneous acupoint electrical stimulation combined with endovascular physiotherapy on endometrial receptivity and S100A11 expression during freeze-thawing embryo transfer period in patients with thin endometrium with kidney-yang deficiency

Not yet recruiting
1
40
 
Cavity therapy ;-
Shandong Hospital of Traditional Chinese Medicine; Shandong Hospital of Traditional Chinese Medicine, General project of National Natural Science Foundation of China: Study on TCM Syndrome of Phlegm-Dampness PCOS Infertility Based on Follicular Fluid Proteomics
Thin endometrium
 
 
ChiCTR2200060793: Clinical effect of moxibustion on infertility with renal deficiency and blood stasis and low ovarian reserve function

Recruiting
1
60
 
Moxibustion combined with Western medicine ;Western medicine
Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine; Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Postgraduate Graduation Project
decline in ovarian reserve
 
 
ChiCTR2200065333: Canceled by the investigator. Effect of Xiaochaihu Decoction and its main components on oocyte quality and IVF outcome in infertility patients with liver stagnation and Qi stagnation

Not yet recruiting
1
120
 
None ;Xiaochaihu decoction orally
Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine; Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine, Self-raised funds
infertility
 
 
ChiCTR2300070757: Study on the critical value of Chinese version of Infertility Self-Efficacy Scale

Recruiting
1
400
 
None
Women and Children's Hospital of Chongqing Medical University; Women and Children's Hospital of Chongqing Medical University, Not available
infertility
 
 
NCT04445025: Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis

Active, not recruiting
1
30
US
Elagolix 200 MG, Leuprolide Acetate 3.75 MG/ML, Lab work
Colorado Center for Reproductive Medicine, AbbVie
Infertility, Endometriosis
09/24
12/24
Alleviate, NCT06026553: Assessing Ketorolac (Toradol) at Oocyte Retrieval

Recruiting
1
400
US
Ketorolac (Toradol), Placebo (saline)
Shady Grove Fertility Reproductive Science Center
Infertility, Infertility, Female, Oocyte Retrieval, Postoperative Pain, Embryo Transfer
12/23
01/25
NCT05330130: Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells

Recruiting
1
10
RoW
Follitropin beta injection 150 IU, FOLLISTIM AQ, Follitropin beta injection 300 IU
ART Fertility Clinics LLC, Organon and Co
Ovarian Function Insufficiency, Fertility Issues, Infertility,Female, Infertility
12/23
01/24
ChiCTR2200061018: Comparing 150 IU and 225 IU of recombinant FSH in predicted normal responders undergoing GnRH antagonist stimulatio n in IVF/ICSI: a randomised controlled trial

Not yet recruiting
1
328
 
rFSH started with 150 IU/day ;rFSH started with 225 IU/day
Northwest Women's and Children's Hospital; Northwest Women's and Children's Hospital, Research Fund for Young and Middle-Aged Doctors in Reproductive Medicine
Infertility
 
 
NCT06095206: The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site

Recruiting
1
48
RoW
GenSci094
Changchun GeneScience Pharmaceutical Co., Ltd., Affiliated Hospital of North Sichuan Medical College
Infertility
12/23
03/24
NCT03379649: Platelet Rich Plasma for Patients With Recurrent Implantation Failure

Completed
1
50
US
Platelet rich plasma, Placebo
Stanford University
Infertility
12/23
12/23
NCT05969795: Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support

Recruiting
1
342
RoW
Transvaginal ultrasound, Serial serum LH, E2, P4, Progesterone 100 Mg Vaginal Insert, Progesterone 100Mg Vag Tab, Serum P4 day of ET - Control Group, Serum P4 day of ET - Study Group, Embryo transfer, ET, Serum hCG 10 days after ET, Serum P4 10 days after ET
ART Fertility Clinics LLC
Pregnancy Related, Infertility, Female
04/24
09/24
NCT05980091: Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.

Recruiting
1
316
RoW
Transvaginal ultrasound, Serum LH, E2, P4, Estradiol Valerate 2 MG, Estradiol Valerate, Progesterone 100 Mg Vaginal Insert, Progesterone 100 mg, Serum P4 day of ET, Embryo transfer, ET
ART Fertility Clinics LLC
Infertility, Fertility Issues, Infertility, Female
04/24
09/24
ChiCTR2200064870: Clinical study of early cleavage stage embryo fragmentation observation combined with low oxygen concentration culture to improve early embryonic development

Not yet recruiting
1
100
 
hypoxic culture ;none
Zhejiang Provincial People's Hospital; Zhejiang Provincial People's Hospital, Agency-level research topic 2020KY013
infertility
 
 
NCT05792813: Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility

Not yet recruiting
1
162
NA
LGYY, LGYY mimetic, WZYZ, WZYZ mimetic
Xiyuan Hospital of China Academy of Chinese Medical Sciences, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Chengdu Fifth People's Hospital, Shenzhen Traditional Chinese Medicine Hospital
Male Infertility, Asthenozoospermia, Oligoasthenozoospermia
06/24
12/24
NCT06414096: Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome

Not yet recruiting
1
5
US
Follicle Stimulating Hormone
University of Colorado, Denver
Infertility, Obesity
11/25
01/26
ChiCTR2200056972: Comparing nicotinamide ribose with vitamin E to improve fertility in elderly women: a single-center, randomized, parallel trial

Recruiting
1
60
 
Nicotinamide Riboside (NR) ;Vitamin E
The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, The First Affiliated Hospital of Zhengzhou University
Infertility in elderly patients and ovarian dysfunction
 
 
ChiCTR2200061977: A randomized study to compare dual trigger and hCG trigger in antagonist protocol in patients with low response

Not yet recruiting
1
450
 
HCG + Gn ;HCG trigger
CITIC Xiangya Reproductive and Genetic Hospital; CITIC Xiangya Reproductive and Genetic Hospital, self-funded
Infertility
 
 

Not yet recruiting
1
780
 
Fresh transfer ;Frozen transfer
Northwest Women‘s and Children's Hospital; Northwest Women‘s and Children's Hospital, China Association for the Promotion of Human Health
Infertility
 
 
NCT06045351: Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome

Recruiting
1
142
RoW
Vitamin D, Experimental, Group A, Active Comparator, Group B
Aga Khan University, Pakistan Science Foundation
Anovulatory Infertility
12/24
12/25
NCT04717362: The Effects of Natesto For Treatment Of Hypogonadism

Withdrawn
1
40
NA
Natesto Nasal Product
Baylor College of Medicine
Hypogonadism, Male, Infertility, Male, Testosterone Deficiency
12/24
12/24
NCT05495711: hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility

Recruiting
1
24
RoW
human umbilical cord mesenchymal stem cell complex collagen, intrauterine injection
Sclnow Biotechnology Co., Ltd.
Infertility, Female
03/25
04/25
ChiCTR2200063799: A prospective randomized controlled study on the necessity of GnRH-a addition in patients with LH < 6 IU/L during controlled ovarian hyperstimulation

Not yet recruiting
1
870
 
Add Cetrorelix ;Without cetrorelix
Peking University Shenzhen Hospital; Peking University Shenzhen Hospital, High level hospital research funds
infertility
 
 
ChiCTR2300069139: Study on the pregnancy outcome of adding rLH at different times in the elderly women undergoing IVF

Recruiting
1
816
 
None ;None
Xiamen Women and Children's Hospital; Xiamen Women and Children's Hospital, Xiamen Women and Children's Hospital
Women infertility
 
 

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