Infertility |
ACTRN12613001316796: Endometrial preparation for cryo embryo transfer: effect of Gonadotropin Releasing Hormone Agonists (GnRHa) coupled with oestrogen and progesterone on hormonal profile and pregnancy rate |
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| Not yet recruiting | 1 | 140 | | | Elshatby University Maternity Hospital Department of Obstetrics and Gynecology, Elshatby University Maternity Hospital
Department of Obstetrics and Gynecology
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ACTRN12610000064000: A prospective Randomised Controlled Trial assessing recombinant Luteinising Hormone supplementation in patients with a relative reduction in Luteinising Hormone (LH) levels during Vitro Fertilisation/Intracytoplasmic sperm Injection (IVF/ICSI) treatment. |
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| Recruiting | 1 | 697 | | | IVFAustralia, IVFAustralia | Infertility treated with IVF, Low serum LH levels during IVF treatment cycles. | | | | |
ChiCTR-ONRC-14005128: The clinical outcome of different types of progesterone used for ovarian stimulation in normalovulatory women |
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| Recruiting | 1 | 360 | | MPA 10mg/d ;P 200mg/d ;dydrogesterone 20mg/d | Shanghai Ninth People's Hospital; Shanghai Ninth People's Hospital, National nature science foundation of China | infertility | | | | |
ChiCTR-OPN-14005276: the clinical outcome of HMG, HP-HMG, u-FSH and MPA used for ovarian stimulation in normalovulatory women |
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| Recruiting | 1 | 180 | | HMG and MPA ;HP-HMG and MPA ;u-FSH and MPA | Shanghai Ninth People's Hospital; Level of the institution:, National nature science foundation of China | infertility | | | | |
ChiCTR-IPC-14005419: The effectiveness of endometrial injury in different phase of menstrual cycle: a prospective controlled clinical study |
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| Not yet recruiting | 1 | 400 | | lendometrial injury in luteal phase ;lendometrial injury in menstrual period ;lendometrial injury in luteal phase ;lendometrial injury in menstrual period | First Affilited Hospital of Zhengzhou Univercity; Level of the institution:, MerckSerono China Research Fund for Fertility Experts | Female Infertility | | | | |
ChiCTR1800014443: A study to compare the endometrial features of women who did and did not benefit from endometrial scratch in the cycle preceding frozen embryo transfer |
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| Not yet recruiting | 1 | 120 | | Luteinization Hormone (LH) surge + 7 days | Prince of Wales Hospital, The Chinese University of Hong Kong; Level of the institution:, N/A | infertility | | | | |
ChiCTR1900021049: Validation of a Fertility Status Awareness Tool (FertiSTAT) to Access the Fertility Problem among Hong Kong Chinese |
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| Recruiting | 1 | 250 | | Nil | Department of O&G, Prince of Wales Hospital, Chinese University of Hong Kong; Level of the institution:, Nil | Pregnant and infertile women | | | | |
ChiCTR-ONRC-12001858: The different pretreatment before the GnRH antagonist protocol in the application of in vitro fertilization and embryo transfer |
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| Completed | 1 | 319 | | used short acting GnRH agonist before GnRH antagonist treatment ;used short-acting oral contraceptives before GnRH antagonist treatment ;that untreated before GnRH antagonist treatment | Shenzhen Hospital of Peking University; Shenzhen Hospital of Peking University, self | infertility | | | | |
ChiCTR1800018075: The effects of ET catheter depth on the pregnency outcome of in vitro fertilization and embryo transfer: a prospective randomized trial |
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| Recruiting | 1 | 250 | | The ET catheter depth in the uterin cavity is 10mm ;The ET catheter depth in the uterin cavity is 20mm | Department of Gynecology & Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Department of Gynecology & Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Department of Gynecology & Obstetrics,Sun Yat-sen Memorial Hospital | Infertility | | | | |
ChiCTR-CPC-14005382: Research on expression of SPAG9 and anti-SPAG9 autoantibody in peripheral blood with testicular fine needle aspiration |
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| Recruiting | 1 | 50 | | Testis puncture | Jun-ping Xing; None, The tutor subject | Male infertility | | | | |
ChiCTR-IPR-14005293: The influence of initiation of progesterone supplementation in IVF-ET outcome-a prospective, randomized, controlled trial. |
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| Not yet recruiting | 1 | 200 | | initiation of progesterone one day after oocyte re | Reproductive Center, First Affiliated Hospital, SUN Yat- sen University, Guangzhou; SUN Yat- sen University, Medical Scientific Research Funds of Guangdong Province (B2012091) | infertility | | | | |
ChiCTR-IPC-14005535: The infulunce of TEAS for patients undergoing IVF-ET aspect of ovarian response and pregnancy outcome |
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| Not yet recruiting | 1 | 300 | | 2Hz TEAS ;2Hz TEAS ;2Hz TEAS ;2Hz TEAS ;2Hz TEAS ;2Hz TEAS | Department of Obstetrics and Gynecology, Reproductive Medical Center, Peking University Third Hospital; Peking University Third Hospital, TEAS in reproductive medicine application, the Ministry of health industry project (201302013) | infertility | | | | |
ChiCTR-IPR-14005580: The relationship between Metabolic enzyme gene polymorphism and idiopathic male infertility |
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| Not yet recruiting | 1 | 600 | | testosterone undecanoate+tamoxifen+ vitamin C+ vitamin E + coenzyme Q10 ;testosterone undecanoate+tamoxifen ;Placebo | Affiliated Hospital of Guiyang Medical College; Affiliated Hospital of Guiyang Medical College, The National Natural Science Fund | Male Infertility | | | | |
ChiCTR-OPC-14005553: Clinical study of the treatment of infertility caused by severe intrauterine adhesions by collagen scaffold loaded with umbilical cord blood-derived mesenchymal stem cells |
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| Completed | 1 | 20 | | hysteroscopy adhesiolysis followed by collagen scaffold loaded with umbilical cord blood-derived mesenchymal stem cells treatment | The Affiliated Drum Tower Hospital of Nanjing University Medical School; The Affiliated Drum Tower Hospital of Nanjing University Medical School, Strategic Priority Research Program of Chinese Academy of Science | infertility caused by severe intrauterine adhesions | | | | |
ChiCTR-IPR-15007251: The clinical outcome of MPA and Duphaston in Primed-progesterone ovarian stimulation protocol for normalovulatory undergoing IVF cycle |
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| Not yet recruiting | 1 | 200 | | HMG AND MPA ;HMG AND Duphaston | Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine; Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Three-year Plan on Promoting TCM Development Funds and Shanghai Science and Technology Development Funds | infertility | | | | |
ChiCTR-IPR-15006369: The improvement of endometrial receptivity in PCOS patients by Vitamin D3: a prospective randomized controlled clinical trial |
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| Not yet recruiting | 1 | 420 | | Placebo for three months ;Vitamin D3 for three months ;Placebo for three months ;Vitamin D3 for three months | First Affilited Hospital of Zhengzhou Univercity; First Affilited Hospital of Zhengzhou Univercity, MerckSerono China Research Fund for Fertility Experts | Female Infertility | | | | |
NCT03634644: Omega-3 PUFA for Treatment of Patients With Idiopathic Oligoasthenoteratospermia |
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| Recruiting | 1 | 30 | RoW | Omega 3 fatty acid, Placebo Capsule, Placebo oral capsule | Jinling Hospital, China | Male Infertility Due to Hypospermatogenesis | 03/19 | 10/22 | | |
| Not yet recruiting | 1 | 30 | | Endometrium biopsy | Xiangya Hospital, Central-south University; Xiangya Hospital, Central-south University, None | Infertility | | | | |
NCT04541459: Validation of New Devices Against Ambient Electromagnetic Radiation |
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| Recruiting | 1 | 40 | US | new device against ambient electromagnetic radiation, sham device against ambient electromagnetic radiation | Waveguard GmbH | Male Infertility | 03/21 | 04/21 | | |
NCT04676269: Amnion Bilayer and Stem Cell Combination Therapy on Thin Endometrium Infertile Patients |
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| Recruiting | 1 | 40 | RoW | Amnion only, Amnion - endometrium cells, Amnion - amnion epithelial cells, Amnion-EnSC-AESC | Indonesia University | Cell- and Tissue-Based Therapy | 07/21 | 12/21 | | |
NCT04361175: Cost Effectiveness Analysis for Induction of Ovulation in the Polycystic Ovary Syndrome by Letrozole Versus Clomiphene Citrate |
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| Not yet recruiting | 1 | 212 | NA | Letrozole, Clomiphine Citrate | Assiut University | Infertility | 09/21 | 12/21 | | |
ChiCTR2000039182: Comparison of endometrial receptivity between fresh and frozen–thawed embryo transfer after GnRH-antagonist protocol: a randomized controlled trial |
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| Recruiting | 1 | 820 | | fresh embryo transfer ;frozen–thawed embryo transfer | The First People Hospital of Yunnan; The First People Hospital of Yunnan, Reproductive genetic disease clinical medical center in Yunnan Province | infertility | | | | |
NCT02912104: A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Failure |
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| Completed | 1 | 36 | RoW | human amniotic epithelial cells (hAECs) transplantation, hAECs transplantation | International Peace Maternity and Child Health Hospital, Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China | Primary Ovarian Insufficiency, Premature Ovarian Failure, Infertility | 01/22 | 01/23 | | |
PTX-Zn, NCT05178953: The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia |
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| Recruiting | 1 | 160 | RoW | Zinc Sulfate 220 mg Capsules, zinc, Pentoxifylline, Trental | Arak University of Medical Sciences | Men Infertility | 01/22 | 01/22 | | |
ChiCTR2100050198: A randomized controlled trial on the effect of different COS protocols in IVF |
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| Recruiting | 1 | 500 | | new trigger protocol ;HCG trigger ;HCG+Gnah ;Gnah ;a novel protocol | Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine; Reproductive Hospital affiliated to Jiangxi University of Traditional Chinese Medicine, Key Research and Development Projects of JiangXi Province | Infertility | | | | |
NCT04878705: Safety and Tolerability of TWP-201 in Healthy Female Subjects |
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| Recruiting | 1 | 48 | RoW | TWP-201, placebo | Shandong TheraWisdom Biopharma Co., Ltd. | Infertility | 10/22 | 12/22 | | |
ChiCTR2200060212: Application of immersive VR technology in improving the outcome of assisted reproduction |
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| Recruiting | 1 | 240 | | Wear VR equipment one day before operation and watch 3D video of oocyte retrieval operation ;Wear VR equipment and watch videos during operation ;After operation, wear VR equipment, watch videos or play games ;routine care | Women and Children’s Hospital of Chongqing Medical University; Women and Children’s Hospital of Chongqing Medical University, Chongqing Municipal Health Commission Project | infertility | | | | |
PCOS, NCT04987632: Effect of Acupuncture Plus Governor Vessel Moxibustion Combined With Letrozole on Live Birth in Anovulatory Infertile Women With Spleen-kidney Yang Deficiency |
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| Not yet recruiting | 1 | 90 | NA | Letrozole, acupuncture, Governor vessel moxibustion | Qiu-ping Lin | PCOS, Infertility, Female | 12/22 | 12/22 | | |
ChiCTR2200057987: To explore the effect of Zishen Quyu Jiedu Recipe on the outcome of IVF-ET in patients with endometriosis of kidney deficiency and blood stasis type based on Wnt signal pathway |
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| Not yet recruiting | 1 | 99 | | Shishen Quyu detoxifying granules ;Placebo ;Placebo | Affiliated Hospital of Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Chinese Medicine, A Chinese Medical Syndrome Study of infertility due to phlegm dampness type PCOS based on follicular fluid proteomics | Endometriosis | | | | |
NCT05390606: Effects of Flourish HEC and BioGenesis to Improve Conception |
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| Terminated | 1 | 1 | US | Flourish HEC and BioGenesis | Vaginal Biome Science, Dr. Aimee Eyvazzadeh, Inc. | Infertility, Infertility Unexplained | 03/23 | 03/23 | | |
ChiCTR2200062915: Study on improving oocyte quality of infertile patients with phlegm-dampness PCOS by electroacupuncture |
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| Not yet recruiting | 1 | 70 | | Electropuncture ;None | Affiliated Hospital of Shandong University of Traditional Chinese Medicine; Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Natural Science Foundation of Shandong Province | PCOS | | | | |
ACTRN12619001593123: ELONVA FLARE PROTOCOL: a new approach for poor responders in superovulation for In Vitro Fertilisation (IVF). |
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| Completed | 1 | 20 | | | UNSW, Merck, Sharp and Dohme | Infertility | | | | |
infertility, NCT06342856: Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia |
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| Recruiting | 1 | 120 | RoW | co enzyme Q10 , L- Carnitine | Ain Shams University | Infertility Unexplained, Oligospermia | 06/24 | 07/24 | | |
ChiCTR2200057985: Effect of percutaneous acupoint electrical stimulation combined with endovascular physiotherapy on endometrial receptivity and S100A11 expression during freeze-thawing embryo transfer period in patients with thin endometrium with kidney-yang deficiency |
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| Not yet recruiting | 1 | 40 | | Cavity therapy ;- | Shandong Hospital of Traditional Chinese Medicine; Shandong Hospital of Traditional Chinese Medicine, General project of National Natural Science Foundation of China: Study on TCM Syndrome of Phlegm-Dampness PCOS Infertility Based on Follicular Fluid Proteomics | Thin endometrium | | | | |
ChiCTR2200060793: Clinical effect of moxibustion on infertility with renal deficiency and blood stasis and low ovarian reserve function |
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| Recruiting | 1 | 60 | | Moxibustion combined with Western medicine ;Western medicine | Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine; Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Postgraduate Graduation Project | decline in ovarian reserve | | | | |
ChiCTR2200065333: Canceled by the investigator. Effect of Xiaochaihu Decoction and its main components on oocyte quality and IVF outcome in infertility patients with liver stagnation and Qi stagnation |
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| Not yet recruiting | 1 | 120 | | None ;Xiaochaihu decoction orally | Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine; Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine, Self-raised funds | infertility | | | | |
ChiCTR2300070757: Study on the critical value of Chinese version of Infertility Self-Efficacy Scale |
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| Recruiting | 1 | 400 | | None | Women and Children's Hospital of Chongqing Medical University; Women and Children's Hospital of Chongqing Medical University, Not available | infertility | | | | |
NCT04445025: Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis |
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| Active, not recruiting | 1 | 30 | US | Elagolix 200 MG, Leuprolide Acetate 3.75 MG/ML, Lab work | Colorado Center for Reproductive Medicine, AbbVie | Infertility, Endometriosis | 09/24 | 12/24 | | |
| Recruiting | 1 | 400 | US | Ketorolac (Toradol), Placebo (saline) | Shady Grove Fertility Reproductive Science Center | Infertility, Infertility, Female, Oocyte Retrieval, Postoperative Pain, Embryo Transfer | 12/23 | 01/25 | | |
NCT05330130: Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells |
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| Recruiting | 1 | 10 | RoW | Follitropin beta injection 150 IU, FOLLISTIM AQ, Follitropin beta injection 300 IU | ART Fertility Clinics LLC, Organon and Co | Ovarian Function Insufficiency, Fertility Issues, Infertility,Female, Infertility | 12/23 | 01/24 | | |
ChiCTR2200061018: Comparing 150 IU and 225 IU of recombinant FSH in predicted normal responders undergoing GnRH antagonist stimulatio n in IVF/ICSI: a randomised controlled trial |
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| Not yet recruiting | 1 | 328 | | rFSH started with 150 IU/day ;rFSH started with 225 IU/day | Northwest Women's and Children's Hospital; Northwest Women's and Children's Hospital, Research Fund for Young and Middle-Aged Doctors in Reproductive Medicine | Infertility | | | | |
NCT06095206: The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site |
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| Recruiting | 1 | 48 | RoW | GenSci094 | Changchun GeneScience Pharmaceutical Co., Ltd., Affiliated Hospital of North Sichuan Medical College | Infertility | 12/23 | 03/24 | | |
NCT03379649: Platelet Rich Plasma for Patients With Recurrent Implantation Failure |
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| Completed | 1 | 50 | US | Platelet rich plasma, Placebo | Stanford University | Infertility | 12/23 | 12/23 | | |
NCT05969795: Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support |
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| Recruiting | 1 | 342 | RoW | Transvaginal ultrasound, Serial serum LH, E2, P4, Progesterone 100 Mg Vaginal Insert, Progesterone 100Mg Vag Tab, Serum P4 day of ET - Control Group, Serum P4 day of ET - Study Group, Embryo transfer, ET, Serum hCG 10 days after ET, Serum P4 10 days after ET | ART Fertility Clinics LLC | Pregnancy Related, Infertility, Female | 04/24 | 09/24 | | |
NCT05980091: Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration. |
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| Recruiting | 1 | 316 | RoW | Transvaginal ultrasound, Serum LH, E2, P4, Estradiol Valerate 2 MG, Estradiol Valerate, Progesterone 100 Mg Vaginal Insert, Progesterone 100 mg, Serum P4 day of ET, Embryo transfer, ET | ART Fertility Clinics LLC | Infertility, Fertility Issues, Infertility, Female | 04/24 | 09/24 | | |
ChiCTR2200064870: Clinical study of early cleavage stage embryo fragmentation observation combined with low oxygen concentration culture to improve early embryonic development |
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| Not yet recruiting | 1 | 100 | | hypoxic culture ;none | Zhejiang Provincial People's Hospital; Zhejiang Provincial People's Hospital, Agency-level research topic 2020KY013 | infertility | | | | |
NCT05792813: Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility |
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| Not yet recruiting | 1 | 162 | NA | LGYY, LGYY mimetic, WZYZ, WZYZ mimetic | Xiyuan Hospital of China Academy of Chinese Medical Sciences, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Chengdu Fifth People's Hospital, Shenzhen Traditional Chinese Medicine Hospital | Male Infertility, Asthenozoospermia, Oligoasthenozoospermia | 06/24 | 12/24 | | |
NCT06414096: Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome |
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| Not yet recruiting | 1 | 5 | US | Follicle Stimulating Hormone | University of Colorado, Denver | Infertility, Obesity | 11/25 | 01/26 | | |
ChiCTR2200056972: Comparing nicotinamide ribose with vitamin E to improve fertility in elderly women: a single-center, randomized, parallel trial |
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| Recruiting | 1 | 60 | | Nicotinamide Riboside (NR) ;Vitamin E | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, The First Affiliated Hospital of Zhengzhou University | Infertility in elderly patients and ovarian dysfunction | | | | |
ChiCTR2200061977: A randomized study to compare dual trigger and hCG trigger in antagonist protocol in patients with low response |
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| Not yet recruiting | 1 | 450 | | HCG + Gn ;HCG trigger | CITIC Xiangya Reproductive and Genetic Hospital; CITIC Xiangya Reproductive and Genetic Hospital, self-funded | Infertility | | | | |
| Not yet recruiting | 1 | 780 | | Fresh transfer ;Frozen transfer | Northwest Women‘s and Children's Hospital; Northwest Women‘s and Children's Hospital, China Association for the Promotion of Human Health | Infertility | | | | |
NCT06045351: Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome |
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| Recruiting | 1 | 142 | RoW | Vitamin D, Experimental, Group A, Active Comparator, Group B | Aga Khan University, Pakistan Science Foundation | Anovulatory Infertility | 12/24 | 12/25 | | |
NCT04717362: The Effects of Natesto For Treatment Of Hypogonadism |
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| Withdrawn | 1 | 40 | NA | Natesto Nasal Product | Baylor College of Medicine | Hypogonadism, Male, Infertility, Male, Testosterone Deficiency | 12/24 | 12/24 | | |
NCT05495711: hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility |
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| Recruiting | 1 | 24 | RoW | human umbilical cord mesenchymal stem cell complex collagen, intrauterine injection | Sclnow Biotechnology Co., Ltd. | Infertility, Female | 03/25 | 04/25 | | |
ChiCTR2200063799: A prospective randomized controlled study on the necessity of GnRH-a addition in patients with LH < 6 IU/L during controlled ovarian hyperstimulation |
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| Not yet recruiting | 1 | 870 | | Add Cetrorelix ;Without cetrorelix | Peking University Shenzhen Hospital; Peking University Shenzhen Hospital, High level hospital research funds | infertility | | | | |
ChiCTR2300069139: Study on the pregnancy outcome of adding rLH at different times in the elderly women undergoing IVF |
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| Recruiting | 1 | 816 | | None ;None | Xiamen Women and Children's Hospital; Xiamen Women and Children's Hospital, Xiamen Women and Children's Hospital | Women infertility | | | | |