| Human Immunodeficiency Virus |
| Recruiting | N/A | 536 | US | video informational/educational intervention | The Alternative Sexualities Health Research Alliance | Pre-Exposure Prophylaxis | 06/24 | 12/24 | | |
NCT05925270: Substituting SMSs for Provider-delivered Care to Improve Alcohol Use Outcomes |
|
|
| Active, not recruiting | N/A | 255 | RoW | mhGAP-Remote, mhGAP-Standard | University Hospital, Basel, Switzerland, SolidarMed | Alcohol Use Disorder, Mild, Alcohol Use Disorder, Moderate | 06/24 | 12/24 | | |
| Active, not recruiting | N/A | 10 | US | | Massachusetts General Hospital | HIV, Awaiting Organ Transplant | 07/24 | 12/24 | | |
BIC-STaR, NCT03580668: Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide |
|
|
| Completed | N/A | 201 | Canada | B/F/TAF, Biktarvy® | Gilead Sciences | HIV-1-infection | 06/24 | 06/24 | | |
NCT04142047: Skeletal Muscle Energetics and Fatiguability in Older Individuals |
|
|
| Recruiting | N/A | 200 | US | | Johns Hopkins University, National Institute on Aging (NIA) | HIV, HIV Infections | 07/24 | 07/24 | | |
| Recruiting | N/A | 300 | US | | Massachusetts General Hospital | HIV-exposed Uninfected | 07/24 | 07/24 | | |
| Active, not recruiting | N/A | 5809 | RoW | VITAL model, automated differentiated service delivery | Swiss Tropical & Public Health Institute | HIV Infections | 07/24 | 07/24 | | |
NCT04930367: CombinADO: Evaluation of an Intervention Aimed at Improving HIV Outcomes Among Adolescents and Young Adults Living With HIV in Mozambique |
|
|
| Recruiting | N/A | 2400 | RoW | Radio Ads, Community Sensitization Campaign, Informational Posters, Motivation Walls, Pill Container, CombinADO-specific training for healthcare workers, One Stop Shop Model of Care, Treatment Toolkit, Self-reflection Kit, Peer Support, Informational and motivational Video, Support groups- caregivers of adolescents and young adults living with HIV, Support groups- adolescents and young adults living with HIV, Mental health screening and linkage to adolescent-focused mental health support | Columbia University, University of Cape Town, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | HIV | 07/24 | 07/24 | | |
NCT04814654: CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment. |
|
|
| Active, not recruiting | N/A | 1005 | RoW | CHALO! 2.0, Attention-matched control (AMC), Digital coupon only (DCO) | Albert Einstein College of Medicine, The Humsafar Trust | Hiv | 07/24 | 01/25 | | |
NCT05231707: Simunye: A Couples-focused Intervention for HIV Prevention and Care in South Africa |
|
|
| Recruiting | N/A | 544 | RoW | A couples-focused intervention for HIV prevention and care in South Africa | University of Michigan, University of California, San Francisco, Human Sciences Research Council | Human Immunodeficiency Virus | 07/24 | 07/24 | | |
| Recruiting | N/A | 1650 | Canada | Reveal Rapid TP (from MedMira), INSTI HIV-1/2 HIV test, INSTI Multiplex HIV-1/2 Syphilis | Wellness Wheel Medical Clinic, CIHR Canadian HIV Trials Network, University of Saskatchewan, Saskatchewan Health Authority - Regina Area | Syphilis, HIV Infections | 07/24 | 07/24 | | |
NCT05642858: Text Education About Cardiovascular Health and HIV (TEACH-HIV) |
|
|
| Recruiting | N/A | 260 | US | Digital Educational Messaging | University of California, San Francisco, National Heart, Lung, and Blood Institute (NHLBI) | HIV, Human Immunodeficiency Virus, Cardiovascular Diseases, Atherosclerosis | 12/24 | 07/25 | | |
NCT05896852: Healthy Lifestyles: A Home Based Physical Activity Intervention in Persons Living With HIV |
|
|
| Not yet recruiting | N/A | 50 | NA | physical activity | Georgetown University | HIV-1-infection, Metabolic Syndrome | 07/24 | 10/25 | | |
| Recruiting | N/A | 200 | Europe | | Centre Hospitalier de Saint-Denis | HIV Seropositivity | 07/24 | 10/24 | | |
NCT05087680: An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South |
|
|
| Recruiting | N/A | 66 | US | ACTPrEP, Enhanced Standard of Care | Rhode Island Hospital, University of Mississippi Medical Center | HIV Prevention | 12/25 | 12/25 | | |
NCT06022549: Effects of mHealth Message on Metabolic Syndrome and Bone Loss of HIV Infected Persons in Taiwan |
|
|
| Recruiting | N/A | 400 | RoW | | National Taiwan University | Hiv | 01/25 | 01/25 | | |
NCT05886621: Testing the Integrated mHealth App Intervention "SiS-H" |
|
|
| Recruiting | N/A | 64 | US | Smiling instead of Smoking - HIV, SiS-H, QuitGuide, QG | Massachusetts General Hospital, National Cancer Institute (NCI) | Smoking Cessation | 07/24 | 10/24 | | |
| Not yet recruiting | N/A | 15 | NA | TruTag System, Biktarvy Pill | Brigham and Women's Hospital, Trutag Technologies, Gilead Sciences | Hiv, Medication Adherence, Compliance, Medication | 12/24 | 04/25 | | |
NCT06149624: Supervised Treadmill Intervention to Reduce Inflammation and Depression Through Exercise in HIV: The STRIDE Pilot Study |
|
|
| Not yet recruiting | N/A | 24 | NA | upfront advice to walk, Supervised exercise | University of Minnesota | Depression, Hiv | 05/25 | 05/25 | | |
| Not yet recruiting | N/A | 105 | RoW | Standard of Care (SOC), Adapted Friendship Bench (AFB), Enhanced Friendship Bench (EFB) | University of North Carolina, Chapel Hill, RTI International, National Institute of Mental Health (NIMH) | Depression, Anxiety, Adolescent Behavior, HIV Infections, Immune System Diseases | 04/25 | 04/25 | | |
| Not yet recruiting | N/A | 132 | RoW | TENDAI4PrEP, Enhanced treatment as usual | Massachusetts General Hospital, University of Zimbabwe, Boston University | HIV Infections, Pregnancy Related, Depression, Anxiety | 01/27 | 03/27 | | |
NCT06432725: Joining Under-connected Networks to Optimize "Salud" (Health) ("JUNTOS") |
|
|
| Not yet recruiting | N/A | 245 | US | JUNTOS, Referral Sheet | University of Miami, National Institute of Mental Health (NIMH) | Hiv | 06/26 | 08/26 | | |
NCT06463886: Striving Towards EmPowerment and Medication Adherence R01 |
|
|
| Not yet recruiting | N/A | 250 | US | STEP-AD, Enhanced treatment as usual (E-TAU) | University of Miami, National Institute of Mental Health (NIMH) | Hiv, Mental Health Issue | 06/29 | 06/29 | | |
| Not yet recruiting | N/A | 341 | NA | INSTI Multiplex HIV/Syphilis Antibody Test | Unity Health Toronto | HIV Infections, Syphilis Infection | 12/24 | 12/24 | | |
SANDMAN, NCT06441383: Assessment of Sleep Disordersin People Living With HIV in the Era of New Antiretroviral Therapies in North of France |
|
|
| Not yet recruiting | N/A | 1100 | Europe | Pittsburgh Sleep Quality Index | Tourcoing Hospital | HIV Infections, Sleep Disorder | 12/24 | 12/25 | | |
| Not yet recruiting | N/A | 1500 | NA | HealthMPowerment (HMP) | University of Maryland, Baltimore, University of Florida | Hiv | 09/27 | 06/28 | | |
| Not yet recruiting | N/A | 3591 | NA | Peer Distribution, Community Health Worker Distribution | University of Stellenbosch, Biomedical Research and Training Institute, Zimbabwe, Imperial College London, University of Lincoln, University College London Hospitals, University of Copenhagen, University of Washington, Heidelberg University | HIV Infections | 07/26 | 12/28 | | |
| Recruiting | N/A | 55 | US | Acceptability of Intervention Measure (AIM), Intervention Appropriateness Measure (IAM), Feasibility of Intervention Measure (FIM), HIV Stigma Scale Questionnaire, HIV Treatment Satisfaction Questionnaire status version (HIVTSQs12), HIV Treatment Satisfaction Questionnaire change version (HIVTSQc12), Needs and Barriers Assessment, Pre-visit Outreach, Qualitative interview, Staff education | University of Nebraska, ViiV Healthcare | HIV | 04/26 | 04/26 | | |
NCT04077047: Adolescents Living With HIV (ALWH): Social Networks, Adherence and Retention |
|
|
| Not yet recruiting | N/A | 30 | US, RoW | iEngage, network-based, social support intervention | Wake Forest University Health Sciences, National Institute of Mental Health (NIMH) | HIV/AIDS | 12/24 | 12/25 | | |
| Recruiting | N/A | 1500 | Europe | Cabotegravir 600mg/3mL, Rilpivirine 900mg/3mL | Castagna Antonella | HIV Infections | 07/24 | 07/27 | | |
IMPACT, NCT06444360: Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Young Gay/Bisexual Minority Men |
|
|
| Not yet recruiting | N/A | 360 | US | IMPACT, eSOC | Westat, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Drug Abuse (NIDA), National Institute of Mental Health (NIMH) | HIV | 12/28 | 12/28 | | |
| Not yet recruiting | N/A | 420 | US | CHW Sessions, WiseApp, CleverCap | Columbia University, University of Alabama at Birmingham, Health Services Center, Inc., Unity Wellness Center, Louisiana State University Health Sciences Center in New Orleans, University of Mississippi Medical Center, National Institute on Minority Health and Health Disparities (NIMHD) | HIV/AIDS | 07/27 | 12/27 | | |
MATLINK, NCT04947475: Project Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community |
|
|
| Active, not recruiting | N/A | 835 | RoW | SBIRT | Yale University, Ukrainian Institute on Public Health Policy, AFEW Kyrgyzstan, AFI - Act For Involvement, National Institute on Drug Abuse (NIDA) | Opioid-use Disorder, HIV Infections, Tuberculosis, Hepatitis C, Hepatitis B, Depression, Syphilis | 07/24 | 07/24 | | |
| Recruiting | N/A | 240 | US | Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised, Structured Clinical Interview For DSM-5 Sleep Disorders-Revised (SCISD-R), Resmed ApneaLink Air device (Resmed, San Diego, CA)., Home Sleep Test, Quantitative Sensory testing (QST), OraQuick Advance Rapid HIV 1/2 Swab test, OraQuick, Cluster of Differentiation 4 (CD4) and Viral load | University of Alabama at Birmingham, National Heart, Lung, and Blood Institute (NHLBI) | HIV, Insomnia | 07/24 | 07/24 | | |
| Active, not recruiting | N/A | 880 | RoW | SOC-REC/SOC-OIC, Standard of care-routine education and counseling/Outreach and Intensified Counselling, SOC-REC/CCT, Standard of care-routine education and counseling/Conditional Cash Transfer, SOC-REC/IP-NAV, Standard of care-routine education and counseling/In-Person Peer Navigation, E-NAV/SOC-OIC, Electronic-Navigation/SOC-Outreach and Intensified Counseling, E-NAV/CCT, Electronic-Navigation/Conditional cash transfer, E-Nav/IP-NAV, Electronic-Navigation/In-Person Peer Navigation | Washington University School of Medicine, University of Colorado, Denver, University of California, San Francisco, University of California, Berkeley, Kenya Medical Research Institute | HIV/AIDS | 09/24 | 09/24 | | |
PrEPARE, NCT05482360: Testing Implementation Strategies to Improve Delivery of PrEP for Pregnant and Postpartum Women in Kenya |
|
|
| Recruiting | N/A | 6000 | RoW | PrEP Optimization Interventions | University of Washington, National Institute of Mental Health (NIMH) | Pre-Exposure Prophylaxis, HIV Infections, Pregnancy Related | 07/24 | 07/24 | | |
| Recruiting | N/A | 30 | US | aDOT-CEI, AiCure | University of California, San Francisco, AiCure, RTI International, National Institute of Mental Health (NIMH) | HIV/AIDS, Mobile Health, Young Adults | 07/24 | 07/24 | | |
| Active, not recruiting | N/A | 80 | US | Gaming in a virtual environment | Yale University, National Heart, Lung, and Blood Institute (NHLBI) | Cardiovascular Diseases | 07/25 | 07/25 | | |
NCT04865341: IMB-guided Intervention to Encourage PrEP Uptake Among Young Men Who Have Sex With Men |
|
|
| Recruiting | N/A | 132 | US | IMB | Medical College of Wisconsin | Human Immunodeficiency Virus | 07/24 | 08/24 | | |
NCT02344680: Liver Fibrosis in Zambian HIV-HBV Co-infected Patients |
|
|
| Active, not recruiting | N/A | 303 | RoW | Anti-HIV Agents, Anti-retroviral therapy | University of Alabama at Birmingham, Fogarty International Center of the National Institute of Health, National Institutes of Health (NIH) | Human Immunodeficiency Virus, HBV, Fibrosis, Liver, Cirrhosis, Liver, Hepatocellular Carcinoma, Hepatitis Delta Virus, Alcoholic Hepatitis | 08/24 | 08/24 | | |
NCT04212884: Functional Decline and QoL in People Aging With HIV in Asia |
|
|
| Recruiting | N/A | 1500 | RoW | | Chinese University of Hong Kong, University of Malaya, National Taiwan University, Chongqing Public Health Medical Center, Tan Tock Seng Hospital | Frailty, Disability Physical, HIV/AIDS | 08/24 | 08/24 | | |
NCT03678181: Increasing Engagement and Improving HIV Outcomes Via HealthMPowerment |
|
|
| Completed | N/A | 750 | US | Information Resources, Social Support, HIV Testing | University of Pennsylvania, University of North Carolina, Duke University | HIV Infections, Sexually Transmitted Diseases, Stigma, Social | 10/23 | 10/23 | | |
PRISM Brazil, NCT04114955: Reducing Intersectional Stigma Among High-Risk Women in Brazil to Promote Uptake of HIV Testing and PrEP |
|
|
| Active, not recruiting | N/A | 400 | RoW | Manas por Manas | University of California, San Francisco, National Institute of Mental Health (NIMH), Santa Casa Medical School | HIV Prevention | 08/24 | 08/24 | | |
NCT04779736: Mitigating Sexual Stigma Within Healthcare Interactions Improve Engagement of MSM in HIV Prevention |
|
|
| Enrolling by invitation | N/A | 188 | US | A set of implementation strategies to reduce sexual stigma | Bryan Kutner, National Institute of Mental Health (NIMH), Albert Einstein College of Medicine, Columbia University, New York State Psychiatric Institute | Human Immunodeficiency Virus, Stigma, Social, Patient Engagement | 08/24 | 08/24 | | |
NCT04090723: Using CBPR to Engage Hazardous Drinking Women in the HIV Prevention and Care Continuum |
|
|
| Active, not recruiting | N/A | 12 | US | CBI-CC with peer navigation | Johns Hopkins University, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | HIV, Alcohol; Harmful Use, Mental Health Disorder | 01/24 | 11/24 | | |
NCT05097430: PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP) |
|
|
| Active, not recruiting | N/A | 122 | Canada | Alcohol-focused brief intervention | Centre for Addiction and Mental Health, University Health Network, Toronto, Maple Leaf Research | Hazardous Alcohol Use | 08/24 | 08/24 | | |
NCT05783297: Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence |
|
|
| Recruiting | N/A | 600 | US | Treatment Text (TXTXT), Standard of Care | Ann & Robert H Lurie Children's Hospital of Chicago, University of Illinois at Chicago, KC Care Health Center, Eskenazi Health, Corktown Health Center, Howard Brown Health Center, University of Cincinnati, Indiana University, Duke University, Amity Medical Group, Valley AIDS Council, Baylor College of Medicine, AIDS Healthcare Foundation, Comprehensive Care Center of Southwest Louisiana | HIV Infections | 08/24 | 08/24 | | |
PALESA, NCT06030856: PrEP Restart for Adolescent Girls and Young Women Using STI Self Testing and Assessment of Risk |
|
|
| Recruiting | N/A | 50 | RoW | STI test kits (NG, CT and TV) for home use, Self Administered Behavioural Risk Assessment | Wits RHI Research Centre Clinical Research Site, University of Alabama at Birmingham, University of California, San Francisco | HIV Prevention | 08/24 | 08/24 | | |
NCT06476847: A Simple Intervention to Increase Persistence on PrEP in MSM to Improve Decision Making |
|
|
| Not yet recruiting | N/A | 140 | US, RoW | PrEP persistence | Boston University, National Institute of Mental Health (NIMH) | HIV Infections | 06/26 | 06/26 | | |
MIC-DROP, NCT06183502: HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex With Men |
|
|
| Not yet recruiting | N/A | 1275 | US | Quantitative survey, HIV & STI testing, Qualitative Assessment | Emory University, Centers for Disease Control and Prevention, San Diego State University, University of Chicago | Sexually Transmitted Infections, Gay, Pre Exposure Prophylaxis | 08/26 | 08/26 | | |
NCT06239961: Behavioral Activation, Nutrition, and Activity Intervention |
|
|
| Not yet recruiting | N/A | 10 | US | Social Connection, Nutritional Coaching, Physical Activity Coaching | University of Maryland, Baltimore, National Institute on Aging (NIA) | HIV | 05/25 | 05/26 | | |
WISH, NCT04505371: Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV |
|
|
| Recruiting | N/A | 226 | US | Wellness Intervention for Smokers with HIV | Seattle Institute for Biomedical and Clinical Research, Kaiser Permanente, University of California, Davis, Fred Hutchinson Cancer Center, US Department of Veterans Affairs | HIV Infections, Smoking, Smoking Cessation | 08/24 | 08/25 | | |
| Recruiting | N/A | 300 | Europe | | Rotkreuzklinikum München gGmbH | AIDS Related Lymphoma, HIV Related Lymphoma | 08/24 | 08/29 | | |
IMARA-SA, NCT04758390: A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women |
|
|
| Active, not recruiting | N/A | 1290 | RoW | IMARA (intervention group), Health promotion control group | University of Illinois at Chicago, Desmond Tutu Health Foundation, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Sexually Transmitted Infections, HIV Infections | 08/24 | 08/24 | | |
GAIN, NCT04880200: Improving HIV Diagnosis, Linkage to Care, and Prevention Services With HIV Point-of-Care Nucleic Acid Tests |
|
|
| Recruiting | N/A | 932 | US | POC NAT & Adherence Intervention | University of Washington, Centers for Disease Control and Prevention | HIV Infections | 08/24 | 08/24 | | |
| Recruiting | N/A | 1440 | RoW | Abbott HIV-1/2 VL Point of care Device | MRC/UVRI and LSHTM Uganda Research Unit, Karolinska Institutet, Kilimanjaro Christian Medical Centre, Tanzania, Amsterdam Institute for Global Health and Development, National Institute for Medical Research, Tanzania, Kenya Medical Research Institute, University of Rwanda | HIV, Viral Load, Point of Care Monitoring | 08/24 | 02/25 | | |
NCT05965245: Suubi-Mhealth: A Mobile Health Intervention to Address Depression Among Youth |
|
|
| Recruiting | N/A | 278 | US, RoW | Suubi-Mhealth | Washington University School of Medicine, National Institute of Mental Health (NIMH) | Depression, HIV Infection | 08/24 | 08/24 | | |
| Recruiting | N/A | 900 | US | Project nGage, nGage | University of Chicago, Tulane University, University of Alabama at Birmingham, Birmingham AIDS Outreach, Chicago Center for HIV Elimination, Howard Brown Health, 1917 Clinic at the University of Alabama at Birmingham, Thrive Alabama | HIV Seropositivity | 12/27 | 12/27 | | |
NCT05756790: Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa |
|
|
| Active, not recruiting | N/A | 180 | RoW | Motivational Interviewing, Motivational Interviewing plus Breathalyzer | University of California, San Francisco, National Institute on Alcohol Abuse and Alcoholism (NIAAA), Human Sciences Research Council, City University of New York, School of Public Health | HIV/AIDS, Alcohol Abuse | 08/24 | 08/24 | | |
HARP, NCT06004830: Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1 |
|
|
| Recruiting | N/A | 30 | US | Spironolactone | Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcohol Use Disorder, Hiv | 12/24 | 12/24 | | |
| Recruiting | N/A | 2800 | Europe | blood sampling | ANRS, Emerging Infectious Diseases | HIV-1-infection | 09/24 | 09/25 | | |
| Recruiting | N/A | 900 | Europe | Harm reduction of informal PrEP use, PrEP follow up based on point of care testing | BCN Checkpoint, Projecte dels NOMS-Hispanosida (BCN Checkpoint and BCN PrEP·Point), Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | HIV/AIDS, HIV Infections, Sexually Transmitted Diseases, Vaccination, Adherence, Medication, Side Effect of Drug, Preexposure Prophylaxis | 09/24 | 09/24 | | |
| Active, not recruiting | N/A | 446 | Canada, US | ARTAS Adapted Patient Navigation, Adherence Counseling | Columbia University, Université de Montréal, University of Miami, Weill Medical College of Cornell University, Université de Sherbrooke, Simon Fraser University, National Institute on Drug Abuse (NIDA), Centre hospitalier de l'Université de Montréal (CHUM) | HIV Prevention, HCV, Opioid Use, Intravenous Drug Usage | 12/24 | 12/24 | | |
RESERVIH32, NCT03940521: Bioclinical Evaluation of 2 Biomarkers of Aviremic HIV-1 in CD4+ T Cells of Adults Undergoing Treatment |
|
|
| Recruiting | N/A | 48 | Europe | Bioclinical evaluation | Centre Hospitalier Universitaire de Nīmes, Institut de Génétique Moléculaire de Montpellier | HIV-1-infection | 09/24 | 09/25 | | |
NCT04585165: User-friendly HIV Testing and Counseling Services |
|
|
| Recruiting | N/A | 3000 | RoW | | Institut de Recherche pour le Developpement, Expertise France-L'Initiative, French National Research Institute for Sustainable Development (IRD) | HIV Infections, Sexually Transmitted Infection, Hepatitis B, Chronic, Hepatitis C | 09/24 | 12/24 | | |
SAPPHIRE, NCT04810650: A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa |
|
|
| Active, not recruiting | N/A | 3000 | RoW | Mobility Dynamic Treatment Intervention, Health Living Intervention for Heavy Alcohol Users, Hypertension Linkage, PrEP/PEP at Outpatient Clinics, PrEP/PEP at Antenatal Clinics, PrEP/PEP at Community Households, Standard of Care, Hypertension Community | University of California, San Francisco, Infectious Diseases Research Collaboration, Uganda, Makerere University, Kenya Medical Research Institute, University of California, Berkeley, University College, London, University of Pennsylvania, National Institute of Allergy and Infectious Diseases (NIAID), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Mental Health (NIMH), National Heart, Lung, and Blood Institute (NHLBI) | HIV, Hypertension, Alcohol Drinking, Maternal Child Health, Cost Effectiveness | 09/24 | 09/24 | | |
CETA, NCT04242992: Effectiveness of Transdiagnostic Cognitive Behavioral Therapy for Improving HIV Treatment Outcomes in South Africa |
|
|
| Active, not recruiting | N/A | 400 | RoW | CETA, Short Message Service (SMS) text reminders | Boston University, National Institute of Mental Health (NIMH) | HIV/AIDS, Violence | 05/25 | 05/26 | | |
NCT05405582: Thetha Nami Ngithethe Nawe ("Let's Talk"): Step Wedge cRCT of Peer Led Community PrEP and SRH for Youth in South Africa |
|
|
| Recruiting | N/A | 6000 | RoW | Community-based differentiated HIV prevention incl.PrEP with SRH, Primary Health Clinic based HIV prevention and care | Africa Health Research Institute | HIV-1-infection, Sexually Transmitted Diseases | 02/25 | 05/25 | | |
RESPIRE, NCT05405491: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation |
|
|
| Recruiting | N/A | 160 | Europe | PCR based strategy, Standard care | University Hospital, Lille | Pneumonia, Ventilator-Associated, Pneumonia, Hospital-Acquired, Immunodeficiency | 09/24 | 09/24 | | |
| Completed | N/A | 31 | US | Gain framing plus demographically targeted photos, Loss framing plus demographically targeted photos, Gain framing plus not demographically targeted photos, Loss framing plus not demographically targeted photos | University of North Carolina, Chapel Hill, Gilead Sciences | HIV Prevention | 11/23 | 03/24 | | |
| Recruiting | N/A | 400 | US | Quality Improvement | Duke University | Acute Coronary Syndrome | 09/24 | 10/24 | | |
SEAL, NCT06005298: Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention |
|
|
| Recruiting | N/A | 120 | US | Screening, Brief Intervention, Referral to Treatment (SBIRT) | Shirish S Barve, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections | 10/27 | 10/27 | | |
| Recruiting | N/A | 980 | Europe | Clinical decision support system for screening of migrants using the ISMiHealth software tool., Former intervention: Screening migrant patients using a computer tool adapted to clinical histories in primary care (CRIBMI)., Former acronym of current study: INNoMiGs | Barcelona Institute for Global Health, Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina, Distrito Sanitario Poniente de Almería, Hospital de Poniente, Universidad de Granada, Consorci d'Atenció Primària de Salut de l'Eixample | Hiv, Hepatitis B, Hepatitis C, Tuberculosis, Chagas Disease, Schistosomiasis, Strongyloidiasis, Female Genital Mutilation Type I Status, Female Genital Mutilation Type II Status, Female Genital Mutilation Type III Status | 09/24 | 09/24 | | |
NCT06100211: HIV and Changes in the Gut Microbiome After Changes in Antiretroviral Therapy (ART) |
|
|
| Not yet recruiting | N/A | 15 | NA | | University of Manchester | HIV Infections | 09/24 | 12/24 | | |
TatLat, NCT06441123: Development of a New Family of HIV Latency Regulators (LRAs) Targeting the Tat Viral Protein |
|
|
| Not yet recruiting | N/A | 24 | NA | Blood Sampling | University Hospital, Montpellier, Centre National de la Recherche Scientifique, France, Université Montpellier | HIV Infections | 03/25 | 12/25 | | |
NCT06335121: Implementation of PrEP Care Among Women in Family Planning Clinics |
|
|
| Not yet recruiting | N/A | 250 | NA | POWER Up strategies - | Rush University Medical Center, National Institute of Mental Health (NIMH), University of Illinois at Chicago, Planned Parenthood of Illinois | PrEP Uptake, HIV, Prevention | 12/26 | 06/27 | | |
| Not yet recruiting | N/A | 1573 | NA | HIV testing | Johns Hopkins University, Desmond Tutu HIV Foundation, National Institutes of Health (NIH) | Human Immunodeficiency Virus, Pre-Exposure Prophylaxis, Emergency Department, South Africa | 09/27 | 09/27 | | |
NCT06428643: A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities |
|
|
| Not yet recruiting | N/A | 2322 | NA | Chlamydia, gonorrhea, syphilis, and HIV screening | Tulane University, National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID) | Chlamydia, Gonorrhea, Hiv, Syphilis | 09/28 | 09/29 | | |
NCT06395129: Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries |
|
|
| Not yet recruiting | N/A | 2400 | NA | Low dead-space syringes/needles, LDSS/N, Hepatitis C Antibody Rapid Diagnostic Test, HCV RDT, HIV rapid Diagnostic Test, HIV RDT | Médecins du Monde, UNITAID, Burnet Institute, International Network of People who Use Drugs, University of Bristol, Frontline AIDS, Caritas, Drug-free and preventitve healthcare organisation Nigeria, National Viral Hepatitis and STI Control Program Nigeria, PATH, Population Services International, LSHTM | Drug Use, Hepatitis, Hiv | 12/26 | 12/26 | | |
NCT03268109: COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old |
|
|
| Recruiting | N/A | 330 | Europe | assessment of cognitive impairment | Fondation Ophtalmologique Adolphe de Rothschild | Memory Impairment, HIV/AIDS, Cognitive Impairment | 09/24 | 09/24 | | |
NCT06059443: mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention |
|
|
| Recruiting | N/A | 40 | US | mLab App Plus | Columbia University | HIV Infections, Sexually Transmitted Diseases, Viral, Syphilis | 09/24 | 09/24 | | |
| Recruiting | N/A | 80 | US | exercise training | VA Office of Research and Development, Atlanta VA Medical Center, Baltimore VA Medical Center | HIV Infection | 09/24 | 09/24 | | |
| Enrolling by invitation | N/A | 450 | US | Medication for opioid-use disorder (MOUD) for opioid-use disorder (OUD), HIV testing, HIV treatment for participants living with HIV not already in care, PrEP for participants without HIV, Testing and referral for vaccination or treatment for hepatitis A virus (HAV) and hepatitis B virus (HBV), Testing and referral for treatment for hepatitis C virus (HCV), Sexually transmitted infection (STI) testing and treatment, Primary care, Harm reduction services, Peer navigation, COVID-19 testing and referral for further evaluation, care and/or treatment | HIV Prevention Trials Network, National Institute of Allergy and Infectious Diseases (NIAID), National Institute on Drug Abuse (NIDA) | HIV Infections, Drug Use, Opioid Use, Opioid-use Disorder | 09/24 | 09/24 | | |
| Recruiting | N/A | 300 | RoW | ASA 81mg, Acetylsalicylic acid 81mg, Control Group, no drug, ASA 325mg, Acetylsalicylic acid 325mg | University of Manitoba | HIV | 09/24 | 12/25 | | |
ChiCTR2200057345: The clinical research of urine lipoarabinomannan assay (LF-LAM) for the diagnosis of mycobacterial infection in people living with HIV |
|
|
| Not yet recruiting | N/A | 108 | | For subjects with negative LF-LAM and negative cryptococcal antigen，implement antiretroviral therapy immediately ;For subjects with negative LF-LAM and negative cryptococcal antigen, wait for the return of other clinical results and start antiviral treatment after excluding mycobacterial infection | Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, Science and Technology Commission of Shanghai Municipality | Acquired Immune Deficiency Sydrome, Mycobacterial Infection | | | | |
| Recruiting | N/A | 332 | Europe | Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST) | Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba, ANRS, Emerging Infectious Diseases | Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection | 09/24 | 06/25 | | |
MTM-MI, NCT05063240: Mobile Phone Text Messaging Plus Motivational Interviewing: Effects on Breastfeeding, Child Health Outcomes |
|
|
| Active, not recruiting | N/A | 275 | RoW | Mobile phone text messaging plus prospective motivational interviewing, Standard infant feeding counselling | University of Stellenbosch, McMaster University, Columbia University | Breastfeeding, Exclusive, HIV Infections | 09/24 | 09/24 | | |
| Not yet recruiting | N/A | 218 | NA | Online follow up | Fundació Institut Germans Trias i Pujol, Department of Health, Generalitat de Catalunya, Hospital Vall d'Hebron | HIV, STI | 09/24 | 12/25 | | |
| Recruiting | N/A | 50 | US | LA-CAB, Apretude, TDF/FTC, Truvada | Orlando Immunology Center | HIV Prevention | 09/24 | 09/24 | | |
| Active, not recruiting | N/A | 1148 | Europe | | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Public Health Service of Amsterdam | HIV-1-infection, Comorbidity, Ageing | 10/24 | 10/24 | | |
| Recruiting | N/A | 1000000 | RoW | Routine medical record data collection | Boston University, Bill and Melinda Gates Foundation, University of Witwatersrand, South Africa, Clinton Health Access Initiative Inc. | HIV | 10/24 | 12/24 | | |
| Recruiting | N/A | 1200000 | RoW | Routine medical record data collection | Boston University, Bill and Melinda Gates Foundation, University of Witwatersrand, South Africa, Clinton Health Access Initiative Inc. | HIV | 10/24 | 12/24 | | |
| Recruiting | N/A | 7000000 | RoW | Routine medical record data collection | Boston University, Bill and Melinda Gates Foundation, University of Witwatersrand, South Africa | HIV | 10/24 | 12/24 | | |
V-EXTRA-CVD, NCT04545489: A Nurse-led Intervention to Extend the Veteran HIV Treatment Cascade for Cardiovascular Disease Prevention |
|
|
| Active, not recruiting | N/A | 305 | US | Intervention group, Education control group | VA Office of Research and Development | Cardiovascular Disease, Hypertension, Care Coordination, HIV Treatment Cascade | 10/24 | 03/25 | | |
ChiCTR2100047522: An cohort study of of pulmonary cryptococcosis in adults with non-HIV infection in China |
|
|
| Recruiting | N/A | 1000 | | Nil ;NIl | Shanghai Ruijin Hospital; Shanghai Ruijin Hospital, Self-raised | pulmonary cryptococcosis | | | | |
REST, NCT04946994: Relationship of Exercise, Sleep, and Inflammation Markers in People Living With HIV |
|
|
| Recruiting | N/A | 50 | US | HIIT, CME | Christine Horvat Davey, University of Washington, University of Colorado, Denver | Hiv, Sleep | 10/24 | 10/24 | | |
| Recruiting | N/A | 375 | US | PATH, Camino | San Diego State University | Human Immunodeficiency Virus | 06/24 | 06/25 | | |
| Terminated | N/A | 1 | US | Home visit delivery strategy | University of Arkansas, ViiV Healthcare | HIV-1-infection, Medication Adherence, Satisfaction, Patient | 12/23 | 12/23 | | |
| Recruiting | N/A | 100 | US | | Centers for Disease Control and Prevention | Monkeypox, HIV Infections, AIDS | 10/24 | 10/24 | | |
| Recruiting | N/A | 268 | RoW | JomPrEP App, Inactivated JomPrEP app | University of Connecticut, University of Malaya, National Institutes of Health (NIH), Yale University | HIV Prevention Program | 06/25 | 06/25 | | |