Recruiting

N/A

122

 

Combined echinocandin treatment

the First Affiliated Hospital, College of Medicine, Zhejiang University; the First Affiliated Hospital, College of Medicine, Zhejiang University, National Special Research Program for Important Infectious Diseases

Pneumocystis pneumonia patients infected with HIV

 

 

Recruiting

N/A

200

 

Dual-therapy of lopinavir/ritonavir (LPV/r) plus 3TC (DT group) ;triple-therapy regimen containing tenofovir (TDF), 3TC plus efavirenz (EFV)

Guangzhou Eighth People's Hospital; Level of the institution：, no

AIDS

 

 

Not yet recruiting

N/A

214

 

invitation plus tracing ;invitation

The First Affiliated Hospital, China Medical University; The First Affiliated Hospital, China Medical University, the Mega-Projects of national science research for the 13th Five-Year Plan

HIV/AIDS

 

 

Not yet recruiting

N/A

1100

 

Nil

National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Surplus funds of AIDS and viral hepatitis Major infectious diseases prevention and treatment special project

Acquired immunodeficiency syndrome

 

 

Recruiting

N/A

1200

RoW

University of Chile, ViiV Healthcare

HIV/AIDS, HIV Infections, HIV Seropositivity, Viral Infection

09/19

12/22

Completed

N/A

46

US

Transcranial Direct Current Stimulation (tDCS), tDCS, Computer-based Cognitive Training, Cognitive Training, Watching Educational Videos

Nova Southeastern University

HIV-related Mild Neurocognitive Disorder

11/19

11/19

Completed

N/A

20

 

Antiretroviral therapy ;Antiretroviral therapy+HANK cell therapy

Tianjin Second People Hospital; Tianjin Second People Hospital, Hospital internal project

AIDS

 

 

Not yet recruiting

N/A

120

 

docosahexaenoic acid ;soybean oil

School of Public Health, Fudan University; School of Public Health, Fudan University, , China National Science and Technology Major Projects on Infectious Diseases (grant number 2018ZX10721102-004)

Neurocognitive Impairment

 

 

Not yet recruiting

N/A

300

 

WeChat ;Sport Bracelet

Faculty of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University; Sun Yat-sen University, National Natural Science Foundation of China

HIV/AIDS

 

 

Recruiting

N/A

8

 

Antiretroviral therapy ;Antiretroviral therapy+HANK cell therapy

Tianjin Second People's Hospital; Tianjin Second People's Hospital affiliated to Nankai University, Hospital internal project

AIDS

 

 

Not yet recruiting

N/A

5000

 

non

The Third Hospital of Hebei Medical University; The Third Hospital of Hebei Medical University, raise independently

AIDS and syphilis

 

 

Not yet recruiting

N/A

10

 

NK Cell Infusion ;NK Cell Infusion

Beijing Youan Hospital, Capital Medical University; Looove Biotechnology (Beijing) Limited Company, Looove Biotechnology (Beijing) Limited Company

AIDS

 

 

Completed

N/A

2887

RoW

HIV-1 RNA testing, Xpert HIV-1 RNA testing

University of Oxford, University of Washington, National Institute of Allergy and Infectious Diseases (NIAID)

HIV Infections

07/20

07/22

Recruiting

N/A

300

Europe

REGISTER CREATION

Castagna Antonella, ViiV Healthcare

HIV-1-infection, Multi-Antiviral Resistance

03/20

12/28

Completed

N/A

649

RoW

HIV prevention package including PrEP

ANRS, Emerging Infectious Diseases, Expertise France, Université Montpellier, SESSTIM (IRD, Inserm, Université Aix-Marseille), Coalition Internationale Sida, Institut de Médecine Tropicale, Anvers, Belgique, ARCAD-SIDA MALI, Association African Solidarité, Centre de Recherche Internationale pour la Santé, Université de Ouagadougou, Espace Confiance, Côte d'Ivoire, Espoir Vie-Togo - ONG, Laboratoire BIOLIM, Université de Lomé

HIV/AIDS

12/20

06/21

Completed

N/A

120

 

Jianzhi Ling granule +HAART ;Fenofibrate capsule +HAART

Guangzhou Eighth People's Hospital; Guangzhou Eighth People's Hospital, National Industry Major Project

HIV/AIDS lipid metabolism abnormalities

 

 

Completed

N/A

24

US

Survey, Focus Group, Usability study

University of Florida, National Institute on Alcohol Abuse and Alcoholism (NIAAA)

HIV-1-infection

06/20

07/23

Not yet recruiting

N/A

288

 

Yiaikang capsule ;Jianaikang concentration pill ;Yiaikang capsule analog agent ;Jianaikang concentration pill simulant

The First Affiliated Hospital of Henan University of Chinese Medicine; The First Affiliated Hospital of Henan University of Chinese Medicine, A major science and technology project on prevention and control of major infectious diseases such as AIDS and viral hepatitis

HIV infection

 

 

Recruiting

N/A

40

 

Intravenous anesthesia with Propofol + Dexmedetomidine ;Intravenous anesthesia with Propofol

Beijing You'an Hospital, Capital Medical University; Beijing You'an Hospital, Capital Medical University, Youan Fund of Liver Disease and AIDS

China Primary Health Care Foundation - Youan Foundation of Liver Disease and AIDS

 

 

Not yet recruiting

N/A

 

Nil

the First Affiliated Hospital, College of Medicine, Zhejiang University; the First Affiliated Hospital, College of Medicine, Zhejiang University, National Special Research Program for Important Infectious Diseases

HIV-infected patients complicated with liver disease

 

 

Completed

N/A

2829

US

Clinic-based screening and behavioral interventions

University of California, San Francisco, Kaiser Foundation Research Institute, National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Drug Abuse (NIDA)

Substance Use Disorders, HIV, Depression, Anxiety

07/20

07/20

Recruiting

N/A

50

 

no

The First Affiliated Hospital, College Medicine, Zhejiang University; The First Affiliated Hospital, College of Medicine, Zhejiang University, The National Special Research Program for Important Infectious Diseases (the 13th Five-Year Plan)

AIDS

 

 

Completed

N/A

2000

RoW

Thai Red Cross AIDS Research Centre, Ministry of Health, Thailand

PrEP Test and Treat

08/20

02/23

Recruiting

N/A

1500

 

HIV self-testing kits & HIV standard testing service ;HIV standard testing service

The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical University, the Mega-Projects of National Science Research (13rd Five-Year Plan 2017ZX10201101)

HIV/AIDS

 

 

Completed

N/A

239

US

Medical male circumcision using standard surgical technique.

University of Illinois at Chicago, National Institute of Allergy and Infectious Diseases (NIAID), Atma Jaya Catholic University of Indonesia

HIV Infections

08/23

08/23

Recruiting

N/A

50

 

Subjects avoided eating, drinking, and brushing their teeth 1 hour before saliva collection

Beijing You'an Hospital, Capital Medical University; Beijing You'an Hospital, Capital Medical University, the National Natural Science Foundation of China(grant no. 81372897)；the National Science and Technology Major Project of China during the 13th Five-year Plan Period (grant no. 2017ZX10201101)

Acquired Immune Deficiency Syndrome

 

 

Completed

N/A

6000

RoW

Thai Red Cross AIDS Research Centre, United States Agency for International Development (USAID), Ministry of Health, Thailand, The Government Pharmaceutical Organization, National Health Security Office, Thailand

HIV Test and Treat

10/20

02/23

Recruiting

N/A

1522

RoW

HIV self-testing among female sex workers, Community screening intervention

Kerti Praja Foundation, United Nations

Human Immunodeficiency Virus (HIV)

10/20

10/20

Active, not recruiting

N/A

3600

RoW

NCM-Plus

Johns Hopkins University, National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Medical Research Council, South Africa

MDR-TB, HIV

11/20

Not yet recruiting

N/A

420

 

information intervention ;regular medication reminder

The First Affiliated Hospital, China Medical University; The First Affiliated Hospital, China Medical University, the Mega-Projects of national science research for the 13th Five-Year Plan

HIV/AIDS

 

 

Recruiting

N/A

240

RoW

Nursing Counseling in the change of Alcohol Consumption Behavior in patients receiving HAART, New Counseling, Habitual Counseling, Old Counseling

Universidad Peruana Cayetano Heredia, Fogarty International Center of the National Institute of Health, CARIBBEAN, CENTRAL AND SOUTH AMERICA NETWORK FOR HIV EPIDEMIOLOGY

HIV, Alcohol Drinking

11/20

12/20

Not yet recruiting

N/A

550

 

Nil ;Nil ;Nil ;Nil

Beijing Obstetrics and Gynecology Hospital, Capital Medical University; Beijing Obstetrics and Gynecology Hospital, Capital Medical University, self-raised

AIDS

 

 

Recruiting

N/A

10

 

NK Cell Infusion

NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical University, The Mega-Projects of national science research for the 13th Five-Year Plan

AIDS

 

 

Not yet recruiting

N/A

144

 

Shenling Fuzheng prescription of traditional Chinese medicines ;Simulation agent of Shenling Fuzheng prescription ;Jian Ai Kang prescription of traditional Chinese medicines ;Simulation agent of Jian Ai Kang prescription

The First Affiliated Hospital of Henan College of TCM; State Administration of Traditional Chinese Medicine of the People's Republic of China, National scientific research project of national traditional Chinese Medicine

HIV/AIDS

 

 

Recruiting

N/A

301000

 

HIV universal testing ;HIV specification follow up group

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases (Zhejiang University); State Key Laboratory for Diagnosis and Treatment of Infectious Diseases (Zhejiang University), National Science and Technology Major Project

HIV/AIDS

 

 

Recruiting

N/A

300

 

Antiviral treatment of western medicine + artesunate tablet ;Antiviral treatment of western medicine + moxibustion method

China Academy of Chinese Medical Sciences; National Health and Family Planning Commission of People's Republic of China, Ministry of science and technology, China

Acquired Immune Deficiency Syndrome

 

 

Recruiting

N/A

300

 

TMP-SMX (oral dose of 1.44g, every 8 hours) plus azithromycin (intravenous dose of 0.5g, once a day), for at least 6 weeks ;Synergistic sulfonamides (oral dose of 1.44g, every 8 hours) plus clindamycin (intravenous dose of 0.6 g, every 6 hours), for at least 6 weeks.

Chongqing Public Health Medical Center; Chongqing Public Health Medical Center, The National Science and Technology Major of China of the 13th Five-Year Plan

AIDS-associated toxoplasma encephalitis

 

 

Not yet recruiting

N/A

112

 

Jianpi yiqi Decotion ;Jianpi Yiqi Decoction simulate agent

The First Affiliated Hospital of Henan University of Chinese Medicine; Henan University of Chinese Medicine, National Natural Science Foundation of China-henan joint fund

HIV infection

 

 

Recruiting

N/A

448

 

HIV self-testing kit

School of Public Health (Shenzhen), Sun Yat-sen University; School of Public Health (Shenzhen), Sun Yat-sen University, National natural science foundation of China

HIV/AIDS

 

 

Not yet recruiting

N/A

634

 

compositive intervention that based on cognitive-behavioral intervention ;no intervention

Wuhan Centers of Disease Prevention and Control; Wuhan Centers of Disease Prevention and Control, Wuhan Medical Research Project

HIV/AIDs,depression，PTSD

 

 

Not yet recruiting

N/A

700

 

Specialized guidance of pregnancy; guidance of childbirth ;Anti-virus for positive person; Acceptance of maternal and infant interdiction measures

National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, AIDS and viral hepatitis major infectious disease prevention and treatment special project

AIDS

 

 

Not yet recruiting

N/A

3650

 

No intervention is taken. ;Induction therapy: fluconazole 800mg/d, PO, for 2 weeks; consolidation therapy: fluconazole 400mg/d, PO, for 8 weeks; maintenance therapy: fluconazole 200mg/day, PO, for 1 year. ;Fluconazole 400mg / day, PO, for 1 year. ;When the initial intracranial pressure≥250mmH2O, according to the patients' will, lumbar puncture and removing CSF should be done by regular. ;When the initial intracranial pressure is ≥ 250 mmH2O, lumbar puncture was given daily to reduce intracranial pressure. The intracranial pressure was measured once every 10ml of released cerebrospinal fluid, until the initial intracranial pressure< 50% of the initial intracranial pressure or the pressure< 200 mmH2 ;When the initial intracranial pressure is ≥250mmH2O, the drainage is given, and the cerebrospinal fluid is continuously drained by the improved drainage device to maintain the daily intracranial pressure <200mmH2O; when the intracranial pressure is <200mmH2O for 2 days or more, Stop drainage. ;Amphotericin B deoxycholate combined with flucytosine. Details: amphotericin B deoxycholate 0.5 - 0.7mg / kg, once a day, intravenous drip; flucytosine, daily 100mg / kg, divided into 4 times, PO. Lumbar puncture, biochemical examination of cerebrospinal fluid, cerebrospinal fluid ink staining and fungal culture were p ;Voriconazole combined with flucytosine. Details: Voriconazole was given orally at the induction dose of 400 mg on the first day, once every 12 hours, 200 mg on the second day, once every 12 hours, and flucytosine at the dose of 100 mg/kg per day, four times a day. Lumbar puncture, biochemical ex ;Amphotericin B deoxycholate combined with fluconazole. Details: Amphotericin B deoxycholate 0.5-0.7 mg/kg, once a day, intravenous drip; fluconazole 800 mg, once a day, intravenous drip. Lumbar puncture, biochemical examination of cerebrospinal fluid, cerebrospinal fluid ink staining and fungal culture were performed according to& ;Amphotericin B deoxycholate combined with voriconazole. Details: Voriconazole was administered orally at the induction dose of 400 mg on the first day, once every 12 hours; the maintenance dose of 200 mg on the next day, once every 12 hours; amphotericin B deoxycholate 0.5-0.7 mg/kg once a day, intravenous& ;Subjects start ART after 2 weeks of treatment for cryptococcosis. ;Subjects start ART after 5 weeks of treatment for cryptococcosis. ;SMZ-TMP 1.44g PO q8h + azithromycin 0.5 g IV qd at least for 6 weeks. ;Sulfamethoxazole,Sulfadiazine and Trimethoprim Tablets 1.44g PO q8h + Clindamycin 600mg IV q8h at least for 6 weeks. ;Subjects start ART within 2 weeks of treatment for Toxoplasma gondii. ;Subjects start ART after 2 weeks of treatment for Toxoplasma gondii. ;TMP-SMZ (TMP 15-20 mg/kg/d, SMX 75-100 mg/kg/d) plus prednisone (40 mg 2 times/day, 5 days; 40 mg 1 times/day, 5 days; 20mg 1 time/day, 11 days), total course of treatment 3-4 weeks ;TMP-SMZ (TMP 15-20mg/kg/d, SMX 75-100 mg/kg/d) plus clindamycin (0.6g clindamycin combine with 100ml saline slow) Instillation, 1 time / 6h) plus prednisone (40mg 2 times / day, 5 days; 40mg 1 time / day, 5 days; 20mg 1 time / day, 11 days), the total course of treatment 3-4 weeks. ;Caspofungin (70 mg once daily, 1 day; 50 mg once daily, 20 days) combine with TMP-SMZ (TMP 15-20 mg/kg/d, SMX 75-100 mg/kg/d) plus prednisone (40 mg twice daily, 5 days; 40 mg once daily, 5 days; 20 mg once daily, 11 days), total course of treatment 3-4 weeks. ;Subjects start ART within 1 weeks of treatment for Pneumocystis jirovecii. ;Subjects start ART after 2 weeks of treatment for Pneumocystis jirovecii. ;Induction therapy: sodium foscarnet 60mg/kg, q8h, infusion time > 2h, 2 weeks of treatment; maintenance treatment: sodium foscarnet 90mg/kg/day, intravenous infusion time > 2 h, treatment for at least 2 weeks. At the same time, dexamethasone 5 mg qd was administered intravenously for 4 weeks. ;induction therapy: sodium foscarnet 60mg/kg, q8h, intravenous infusion time > 2h, 2 weeks of treatment; maintenance treatment: sodium foscarnet 90mg/kg/day, intravenous infusion time > 2 h, treatment for at least 2 weeks . At the same time, combined with ganciclovir 0.2 ~ 0.4mg qw intra-balloon injection for ;induction therapy: sodium foscarnet 60mg/kg, q8h, infusion time > 2h, 2 weeks of treatment; maintenance treatment: sodium foscarnet 90mg/kg/day, intravenous infusion time > 2h, treatment for at least 2 weeks. ;Subjects start ART within 2 weeks of treatment for CMV. ;Subjects start ART after 2 weeks of treatment for CMV. ;The amphotericin B deoxycholate was given intravenously for 2 weeks, the dose was 5 mg on the first day, 15 mg on the second day, and 0.5-0.7 mg/kg/d on the third day and later. Then changed to oral itraconazole capsule 200 mg q12 h for 10 weeks, the total course of treatment for 12 ;Voriconazole 4 mg/kg q12h for 4 days, the first day was given a loading dose (voriconazole 6 mg / kg q12 h). After 4 days, it was changed to oral voriconazole capsule 200 mg q12h. After 2 weeks of voriconazole, it was changed to oral itraconazole 200 mg q12 h for 10 weeks. The total& ;Voriconazole 4 mg/kg q12h for 2 weeks，the first day was given a loading dose (voriconazole 6mg/kg q12h), and then changed to oral voriconazole capsule 200 mg q12h for 10 weeks, the total course of treatment for 12 weeks. ;Subjects start ART within 2 weeks of treatment for Talaromyces marneffei. ;Subjects start ART after 2 weeks of treatment for Talaromyces marneffei.

Chongqing Public health medical center; Chongqing Public health medical center, National Science and Technology Major Project -

AIDS opportunistic infections and refractory AIDS

 

 

Not yet recruiting

N/A

155180

 

Multiple HIV testing strategy promotion ;HIV viral load testing among acute MSM infections ;Start rapid ART of newly diagnosed HIV infectors ;nPEP promotion ;Risk assessment of HIV infection ;Youth MSM psychological intervention ;New drug use and high risk sexual behavior intervention

National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention; National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, P.R.China, National Science and Technology Major Project for AIDS and viral hepatitis Prevention and Treatment

HIV/AIDS

 

 

Not yet recruiting

N/A

2000

 

null ;Sending pictures and videos about AIDS Prevention to participants; Creating wechat group with 50 participants in it; Share HIV testing information to wechat moments; Send HIV test kits for home use to participants

School of Public Health of Shandong University; School of Public health of Shandong University, National Key R&D Program

AIDS

 

 

Completed

N/A

300

 

Standard secondary distribution group ;Secondary distribution with monetary incentives ;Secondary distribution with monetary incentives plus peer referral

Dematology hospital of Southern Medical University, UNC project-China; Dematology Hospital of Southern Medical University, UNC Project-China, National Nature Science Foundation of China

HIV

 

 

Recruiting

N/A

34

 

CD20-targeting iNKT cells ;anti-CD19/CD22 CAR-T cells

Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, The National 13th Five-Year Grand Program on Key Infectious Disease Control (2017ZX10202102)

AIDS-related B-cell lymphoma

 

 

Completed

N/A

290

US

WERK Supportive Contact

University of Chicago, Howard Brown Health Center, Ann & Robert H Lurie Children's Hospital of Chicago, National Institute of Mental Health (NIMH)

HIV Prevention

06/20

06/20

Not yet recruiting

N/A

400

NA

Alere TB-LAM

Shanghai Public Health Clinical Center

HIV Infections, Tuberculosis, Non-Tuberculous Mycobacterial Pneumonia

01/21

02/21

Active, not recruiting

N/A

198

US

Evaluate model of care for HCV-infected adults with on-going opioid misuse

University of Maryland, Baltimore

HCV, Burpenorphine, PreP

01/21

08/23

Recruiting

N/A

1200

Europe

MAKASI

French National Agency for Research on AIDS and Viral Hepatitis, Agence Regionale de Sante d'Ile de France

HIV/AIDS, STI

01/21

01/21