NCT00322101: Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia |
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| Completed | 3 | 25 | US, Europe | total-body irradiation, TBI, allogeneic hematopoietic stem cell transplantation, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, mycophenolate mofetil, Cellcept, MMF, busulfan, BSF, BU, Misulfan, Mitosan, Myeloleukon, cyclosporine, ciclosporin, cyclosporin, cyclosporin A, CYSP, Sandimmune, fludarabine phosphate, 2-F-ara-AMP, Beneflur, Fludara, peripheral blood stem cell transplantation, PBPC transplantation, PBSC transplantation, peripheral blood progenitor cell transplantation, transplantation, peripheral blood stem cell, nonmyeloablative allogeneic hematopoietic stem cell transplantation, laboratory biomarker analysis, cytogenetic analysis, flow cytometry, fluorescence in situ hybridization, fluorescence in situ hybridization (FISH), pharmacological study, pharmacological studies, polymorphism analysis, tacrolimus, FK 506, Prograf, methotrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX | Fred Hutchinson Cancer Center, National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHLBI) | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, de Novo Myelodysplastic Syndromes, Myelodysplastic Syndrome With Isolated Del(5q), Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes | 04/12 | 10/14 | | |
NCT02461121: HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risk |
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| Completed | 3 | 156 | RoW | HLA mismatched stem cell, microtransplantation, HLA matched stem cell, nonmyeloablative transplantation, cyclosporine A, GVHD prophylaxis, Mycophenolate mofetil, Ara-C, conditioning reginmen, fludarabine, NST conditioning reginmen, anti-lymphocyte globulin, cyclophosphamide | The Affiliated Hospital of the Chinese Academy of Military Medical Sciences | Acute Myeloid Leukemia | 05/13 | 05/13 | | |
NCT00075478: Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer |
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| Completed | 3 | 87 | US, Europe | Total-Body Irradiation, TBI, Total Body Irradiation, Whole-Body Irradiation, Fludarabine Phosphate, 2-F-ara-AMP, Beneflur, SH T 586, Mycophenolate Mofetil, Cellcept, MMF, Cyclosporine, 27-400, CsA, Neoral, OL 27-400, Sandimmun, Peripheral Blood Stem Cell Transplantation, PBPC transplantation, Peripheral Blood Progenitor Cell Transplantation, Peripheral Stem Cell Support, Peripheral Stem Cell Transplantation | Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI) | Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission, Aggressive Non-Hodgkin Lymphoma, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Diffuse Large B-Cell Lymphoma, Hematopoietic and Lymphoid Cell Neoplasm, Indolent Non-Hodgkin Lymphoma, Mantle Cell Lymphoma, Myelodysplastic/Myeloproliferative Neoplasm, Plasma Cell Myeloma, Refractory Chronic Lymphocytic Leukemia, Refractory Hodgkin Lymphoma, Waldenstrom Macroglobulinemia | 02/14 | 02/14 | | |