Not yet recruiting

N/A

384

 

Deakin University, Medical Research Future Fund (MRFF) Clinical Trials Activity

Oesophageal cancer, Liver cancer, Bile duct cancer, Pancreatic cancer, Stomach cancer

 

 

Recruiting

N/A

50

 

Australasian Gastro-Intestinal Cancer Trials Group (AGITG), Australasian Gastro-Intestinal Cancer Trials Group (AGITG), Monash Health, Monash University

Biliary cancer / Cholangiocarcinoma

 

 

Recruiting

N/A

300

Europe

phenotyping

Inserm U955

Liver Cancer

01/23

01/25

Completed

N/A

35

 

Embolize the portal vein branch of liver lobe to be resected, after selective biliary drainage(SBD) of future liver remnant(FLR) ;The intervention measures are as the same as in PVE group except for PVE under standard procedure of diagnosis and treatment(SBD, volumetric CT, major hepatectomy).

Eastern Hepatobiliary Surgery Hospital; Health Bureau of Shanghai, Scientific Research Project of Health Bureau of Shanghai

Hilar Cholangiocarcinoma

 

 

Recruiting

N/A

40

 

NO ;NO ;Endoscopic Retrograde Biliary Drainage

The Second Hospital of Hebei Medical University; The Second Hospital of Hebei Medical University, The provincal significant medical scientific research subject of Hebei (zd2013017)

The injury of intestinal mocosa

 

 

Completed

N/A

150

 

obtaining circulating tumor cells by GILUPI collec ;obtaining circulating tumor cells by CellSearch ;obtaining circulating tumor cells by Oncoquick

International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University; Eastern Hepatobiliary Surgery Hospital, national nature science foundation of China

Hepatobiliary Tumor (Cholangiocarcinoma)

 

 

Recruiting

N/A

200

 

Chewing gum (sugarless gum, 30 minutes / time, 3 times/day), to end the morning after the first eight days ;Incentives to patients appetite, including: patient favorite diet of media playback, 30 minutes / time, 3 times / day, around the patient can always watch their favorite fruits and can smell fruity taste, and watching around meal and other caregivers ;6 hours after the start of oral small amount of fruit juice (orange juice, apple juice or grape juice, glucose 30g, 100ml), 12 hours after oral administration of enteral nutrition (enteral nutrition suspension Poor's 100 force, Niudi Valencia company), 300ml, divided 4-5 times a day orally, after 24 hours increased to 500ml enteral nutrition, food intake gradually increased until it reaches the normal requiremen ;Early ambulation (day bed activities, events or bedside after a day at least 4-6 hours out of bed)

Second Affiliated Hospital of Kunming Medical University; Second Affiliated Hospital of Kunming Medical University, Self-financing

Abdominal malignancies

 

 

Completed

N/A

80

 

Both biliary resection and caudate lobectomy ;biliary resection only

Eastern Hepatobiliary Hospital, Second Military Medical University; Eastern Hepatobiliary Hospital, Shanghai science and Technology Committee 134119a0202

hilar cholangiocarcinoma

 

 

Completed

N/A

164

 

none

Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University; Department of General Surgery，The 2nd Affiliated Hospital of Harbin Medical University, National Natural Science Foundation of China

Pancreatic cancer，cholangiocarcinoma

 

 

Completed

N/A

62

RoW

Beijing Tsinghua Chang Gung Hospital

Perihilar Cholangiocarcinoma

12/21

12/21

Recruiting

N/A

100

 

Traditional regimens ;Choosing chemotherapy or targeted therapy according to Mini PDX drug sensitivity test

Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine; Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, Hospital Development Center

Bile Duct Cancer，BTC

 

 

Recruiting

N/A

30

 

CAR-T ;CAR-T ;CAR-T ;CAR-T ;CAR-T

West China Hospital, Sichuan University; West China Hospital, Sichuan University, Self-finance and the Fund of Medical New Technology and New Items of West China University

Esophageal carcinoma, colorectal carcinoma, hepatocellular carcinoma, intrahepatic cholangiocarcinoma and pancreatic carcinoma

 

 

Not yet recruiting

N/A

320

 

Flo-Trac/Vigileo system management ;Routine management

Zhongshan hospital, Fudan University; Zhongshan hospital, Fudan University, Supported by Edwards (Shanghai)

Liver tumor

 

 

Recruiting

N/A

 

Shanghai 1st People's Hospital; Shanghai 1st People's Hospital, Shanghai Science and Technology Commission

Cholangiocarcinoma

 

 

Recruiting

N/A

290

 

regional lymphadenectomy ;extended lymphadenectomy

West China Hospital, Sichuan University; West China Hospital of Sichuan University, self-financing

hilar cholangiocarcinoma

 

 

Recruiting

N/A

40

 

apatinib + S-1 ;S-1

Shanghai Dongfang Department of Hepatobiliary Surgery Hospital precision Medicine Center; Shanghai Orient Department of Hepatobiliary Surgery Hospital, none

Biliary tract tumor

 

 

Recruiting

N/A

30

 

Anlotinib

Kui Wang; Eastern Hepatobiliary Surgery Hospital, Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

advanced intrahepatic cholangiocarcinoma

 

 

Recruiting

N/A

17

 

Super circulating tumor infiltrating lymphocytes ;Super circulating tumor infiltrating lymphocytes

Peking Union Medical College Hospital; Peking Union Medical College Hospital, CHINEO MED (BEIJING) CO., LTD.

Biliary Tract Cancer

 

 

Recruiting

N/A

279

RoW

liver transplantation

Istanbul Demiroglu Bilim University

Adult Combined Hepatocellular-Cholangiocarcinoma

02/21

05/22

Recruiting

N/A

30

RoW

Three dimensional laparoscopic resection for pCCA, Open resection for pCCA

Tongji Hospital

Cholangiocarcinoma, Perihilar, Surgery

03/21

03/22

Not yet recruiting

N/A

20

 

LVD ;PVE

West China Hospital, Sichuan University; West China Hospital, Sichuan University, self-raised funds

Liver malignant tumor

 

 

Recruiting

N/A

40

 

Simultaneous radiotherapy and chemotherapy combined with PD-1

Shandong Institute of Cancer Prevention and Control; Shandong Institute of Cancer Prevention and Control, Partial self-expenditure

Cholangiocarcinoma

 

 

Completed

N/A

60

 

ICIs treatment ;ICIs treatment

Fudan University Zhongshan Hospital; Fudan University Zhongshan Hospital, National natural science foundation of China

Malignant Tumor

 

 

Not yet recruiting

N/A

20

NA

Abdominal Regional Perfusion

London Health Sciences Centre

Liver Transplant; Complications, Ischemia Reperfusion Injury, Cirrhosis, Liver Cancer, Liver Metastases, End Stage Liver Disease

06/21

06/26

Available

N/A

NA

MCLA-128

Merus N.V.

NRG1 Fusion, Pancreatic Cancer, Non Small Cell Lung Cancer, Solid Tumor, Unspecified, Adult, Prostate Cancer, Head and Neck Cancer, Colorectal Cancer, Breast Cancer, Cholangiocarcinoma, Renal Cell Carcinoma, Unknown Primary Tumors

 

 

Recruiting

N/A

185

 

R1/R2 resection ;Stereotactic radiotherapy ;Fluorouracil and gemcitabine chemotherapy ;Fluorouracil and gemcitabine chemotherapy ;none

Nanfang Hospital, Southern Medical University; Nanfang Hospital, Southern Medical University, clinical research of Southern Medical University

intrahepatic cholangiocarcinoma

 

 

Recruiting

N/A

186

Europe

Royal Surrey County Hospital NHS Foundation Trust

Pancreatic Cancer, Biliary Tract Cancer

10/21

11/23

Recruiting

N/A

102

RoW

Venous sampling

Huazhong University of Science and Technology

Pancreas Adenocarcinoma

11/21

11/22

Recruiting

N/A

100

 

caudate lobectomy

Peking Union Medical College; Peking Union Medical College, Peking Union Medical College

Hilar cholangiocarcinoma

 

 

Not yet recruiting

N/A

150

 

The drug treatment plan was made by reference to the results of high-throughput drug sensitivity test. ;Use An empirical drug protocol based on the guidelines

First Affiliated Hospital of Chongqing Medical University; First Affiliated Hospital of Chongqing Medical University, Application funding and self financing

liver cancer

 

 

Recruiting

N/A

100

RoW

Two-in-one stent

Ajou University School of Medicine

Extrahepatic Bile Duct Cancer, Pancreatic Cancer, Lymph Node Metastases, Gallbladder Cancer

12/21

12/21

Completed

N/A

60

 

PTCD+ biliary stent + iodine-125 seeds implantation ;PTCD+ biliary stent

The Cancer Hospital of the University of Chinese Academy of Sciences（Zhejiang Cancer Hospital），Institute of Basic Medicine and Cancer（IBMC），Chinese Academy of Sciences; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, The Medicine and Health Discipline Platform Project of Zhejiang Province (grant no. 2018RC019)

Hepatobiliary malignancy

 

 

Recruiting

N/A

30

 

Anlotinib, TACE after hepatectomy 1 month later ;TACE treatment after hepatectomy 1 month later

Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, Chinese Internatinal Medical Coummunication Funding

Hepatocellular Cancer

 

 

Not yet recruiting

N/A

600

 

none

Second Affiliated Hospital of Kunming Medical University; Second Affiliated Hospital of Kunming Medical University, National Natural Science Foundation of China (No. 8176030241)

Cirrhosis

 

 

Recruiting

N/A

20

RoW

Durvalumab Injection, Durvalumab, Imfinzi, Lenvatinib 4 MG, Lenvima

RenJi Hospital

Liver Carcinoma, Liver Transplant; Complications

12/21

12/25

Recruiting

N/A

135

 

Time intervention ; Time intervention ; Time intervention

The General Hospital of Western Theater Command PLA; The General Hospital of Western Theater Command PLA, Project funds

Malignant obstructive jaundice

 

 

Enrolling by invitation

N/A

100

RoW

I-125 seeds loaded stent (self-expanded metal stent with I-125 seeds, Micro-Tech, Nanjing, China), Normal stent (self-expanded metal stent without I-125 seeds, Micro-Tech, Nanjing, China)

Xuzhou Central Hospital

Hilar Cholangiocarcinoma

12/21

06/22

Recruiting

N/A

20

 

NK cells

Beijing Hospital; Beijing ping an pude biotechnology co. LTD, Beijing Ping'an Pude Biotechnology co. LTD

Pancreatic and Cholangiocarcinoma

 

 

Not yet recruiting

N/A

200

 

Intravenous indocyanine green injection

Zhongnan Hospital of Wuhan University; Zhongnan Hospital of Wuhan University, Funds of hospitals

Endoscopic retrograde cholangiopancreatography

 

 

Active, not recruiting

N/A

20

US

radionuclide imaging, radionuclide scanning, positron emission tomography, FDG-PET, PET, PET scan, tomography, emission computed, laboratory biomarker analysis, pharmacological study, pharmacological studies, Cu 64 anti-CEA monoclonal antibody M5A IV

City of Hope Medical Center, National Cancer Institute (NCI)

Breast Cancer, Colon Cancer, Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Gastrointestinal Cancer, Liver and Intrahepatic Biliary Tract Cancer, Lung Cancer, Metastatic Cancer, Pancreatic Cancer, Rectal Cancer, Thyroid Gland Medullary Carcinoma, Unspecified Adult Solid Tumor, Protocol Specific

03/22

12/24

Completed

N/A

1484

Europe, RoW

Pancreaticoduodenectomy

University Hospital Plymouth NHS Trust, University of Plymouth

Pancreatic Cancer, Ampullary Cancer, Bile Duct Cancer, Cholangiocarcinoma, Extrahepatic, Cholangiocarcinoma Resectable, Cholangiocarcinoma of the Extrahepatic Bile Duct, Pancreatic Ductal Adenocarcinoma, Pancreatic Ductal Carcinoma, Surgery, Survivorship, Recurrent Cancer, Cancer Recurrent, Cancer Recurrence, Local Recurrence of Malignant Tumor of Pancreas

03/22

06/23

N/A

80

Europe

Treatment modalities of Traditional Chinese Medicine (Acupuncture, Chinese herbal medicine, Tunia, Chinese dietetics), Standard care

Medical University of Graz

Advanced Cancer, Lung Cancer, Breast Cancer, Colo-rectal Cancer, Pancreas Cancer, Cholangiocarcinoma, Quality of Life, Symptoms and Signs

04/22

07/22

Recruiting

N/A

216

 

Preoperative IQQQA-Liver evaluation ;Regular assessment

Gulou Hospital Affiliated to Medical College of Nanjing University; Gulou Hospital Affiliated to Medical College of Nanjing University, Self-raised Marchds

Hilar cholangiocarcinoma

 

 

Enrolling by invitation

N/A

100

US

Methodist Health System

Intrahepatic Cholangiocarcinoma, Liver Tumor, Metastatic Cancer, Metastatic Liver Cancer

05/22

05/22

Recruiting

N/A

 

Hunan people's Hospital; Hunan Provincial People's Hospital, self-funded

Hepatocellular carcinoma

 

 

Not yet recruiting

N/A

540

 

Percutaneous Transhepatic Biliary Drainage ;Endoscopic Nasobiliary Drainage ;Endoscopic Biliary Stenting

General surgery department, Zhongshan hospital affiliated Fudan University; General surgery department, Zhongshan hospital affiliated Fudan University, scientific research funds of Zhongshan hospital

Malignant tumor of extrahepatic bile duct

 

 

Not yet recruiting

N/A

100

 

TACE + HAIC ;TACE

Fujian Provincial Cancer Hospital; Fujian Provincial Cancer Hospital, Fujian Provincial Cancer Hospital

primary hepatocellular carcinoma

 

 

Recruiting

N/A

300

 

DEB-TACE ;CTACE

Shandong Institute of Cancer Prevention and Treatment; Shandong Institute of Cancer Prevention and Treatment, None

Primary liver cancer

 

 

Not yet recruiting

N/A

100

 

Neoadjuvant therapy ;contrast

Eastern Hepatobiliary Surgery Hospital; Eastern Hepatobiliary Surgery Hospital, Shanghai Hospital Development Center

intrahepatic cholangiocarcinoma