| Cataract |
2017-003277-34: Clinical trial to evaluate the effects of Fydrane® and standard protocol on ocular surface after cataract surgery. Ensayo clÃnico para evaluar los efectos de Fydrane® y del protocolo estándar en la superficie ocular después de la cirugÃa de cataratas. |
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| Ongoing | 4 | 50 | Europe | Solution for injection, Intraocular instillation solution, Fydrane, Colircusi Anestésico Doble, Coliscusà fenilefrina, Colircusà Tropicamida | Laboratoires Théa, Laboratoires Théa | Cataracts Cataratas, Cataracts Cataratas, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | | | | |
NCT04530864: Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy |
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| Not yet recruiting | 4 | 35 | NA | Dextenza 0.4Mg Ophthalmic Insert | Prism Vision Group, Ocular Therapeutix, Inc. | Dry Eye Disease, Cataract Surgery, Ocular Surface Disease | 01/21 | 07/21 | | |
NCT04781335: "A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation" |
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| Recruiting | 4 | 50 | US | Dexycu, Standard of Care post operative eye drops (steroid, antibiotic, NSAID) | The Eye Institute of West Florida, EyePoint Pharmaceuticals, Inc. | Cataract | 06/21 | 08/21 | | |
ENHANCE, NCT04863742: Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL |
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| Recruiting | 4 | 30 | US | Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate | Sight Medical Doctors PLLC, Ocular Therapeutix, Inc. | Dry Eye Syndromes | 07/21 | 09/21 | | |
NCT06497699: A Real-world Study of DEXYCU in the Treatment of Inflammation After Cataract Surgery |
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| Completed | 4 | 263 | RoW | Dexycu | Ocumension Therapeutics (Shanghai) Co., Ltd | Inflammation, Cataract | 07/23 | 12/23 | | |
STAMP, NCT03832179: Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification |
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| Recruiting | 4 | 32 | US | Bevacizumab, Avastin, Ranibizumab, Lucentis, Aflibercept, Eylea, Ozurdex, Dexamethasone implant | Bay Area Retina Associates, Allergan | Diabetic Macular Edema, Cataract | 07/22 | 10/22 | | |
NCT05023304: In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery |
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| Not yet recruiting | 4 | 30 | NA | Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone | Mitchel Ibach, Ocular Therapeutix, Inc. | Cataract | 07/22 | 10/22 | | |
NCT05143281: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1 |
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| Completed | 4 | 23 | US | Dexamethasone 0.4 MG [Dextenza], Dextenza | Grene Vision Group, Ocular Therapeutix, Inc. | Cataract | 02/23 | 02/23 | | |
SUSTAIN, NCT04200651: Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery |
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| Terminated | 4 | 25 | US | Dexamethasone Ophthalmic Insert, DEXTENZA®, Prednisolone Acetate 1% Oph Susp, PRED FORTE®, OMNIPRED® | The New York Eye Surgery Center, Ocular Therapeutix, Inc. | Glaucoma, Cataract | 07/23 | 07/23 | | |
NCT05853978: The Evaluation of Balanced Salt Solution During Cataract Surgery |
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| Recruiting | 4 | 27 | US | BSS Plus, BSS | Adam Fedyk, MD, FACS, Alcon Research | Fuchs Dystrophy, Cataract | 12/23 | 01/24 | | |
NCT05191706: Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract |
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| Recruiting | 4 | 60 | US | Dexamethasone, Prednisolone Acetate Ophthalmic | EyePoint Pharmaceuticals, Inc. | Cataract | 01/25 | 02/25 | | |
NCT04050644: Comparison of Treatment With Preservative-free Dexamethasone 0.1% (Monofree Dexamethason) and Diclofenac 0.1% (Dicloabak) Eye Drops Versus Preserved Dexamethasone 0.1% (Maxidex) and Diclofenac 0.1% (Voltaren Ophtha) Eye Drops After Cataract Surgery |
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| Recruiting | 4 | 100 | Europe | Preservative Free drop treatment, Preserved drop treatment | Universitaire Ziekenhuizen KU Leuven, Laboratoires Thea | Age-related Cataract | 06/24 | 12/24 | | |
| Recruiting | 4 | 44 | US, RoW | CT LUCIA 621P | Carl Zeiss Meditec AG | Cataract | 12/24 | 12/24 | | |
2012-004873-14: Prevention of macular edema after cataract surgery Het voorkomen van netvlieszwelling na een staaroperatie |
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| Ongoing | 3 | 246 | Europe | Bromfenac, Dexamethasone, Bevacizumab, Triamcinolone Acetonide, Yellox, Dexamethasone, Avastin, Triesence, Yellox, Dexamethasone, Avastin, Triesence | University Eye Clinic Maastricht, University Eye Clinic Maastricht UMC, ESCRS (European Society of Cataract & Refractive Surgeons), Bausch + Lomb, ESCRS (European Society of Cataract and Refractive Surgeons), Bausch & Lomb | Pseudophakic cystoid macular edema (PCME) | | | | |
NCT04711642: Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery |
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| Not yet recruiting | 3 | 100 | NA | The study will include three arms, one non interventional and 2 interventions. The intervention arms will include two commercially available sodium hyaluronate 0.1% (Systane ultra plus and Hylo-comod) | Fundación Oftalmológica Los Andes, Alcon Research | Dry Eye Disease, Dry Eye Syndrome, Evaporative Dry Eye, Cataract, Phacoemulsification | 01/22 | 07/23 | | |
NCT04810962: Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery Including a Corneal Endothelial Cell Sub-study |
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| Completed | 3 | 370 | US | APP13007, 0.05%, Matching Vehicle Placebo for APP13007, 0.05% | Formosa Pharmaceuticals, Inc. | Ocular Inflammation and Pain After Cataract Surgery | 07/22 | 07/22 | | |
NCT06429306: Study of Dexycu in Treating Intraocular Inflammation |
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| Completed | 3 | 285 | RoW | Dexycu, Investigational product, Placebo | Ocumension Therapeutics (Shanghai) Co., Ltd | Inflammation, Cataract | 11/23 | 04/24 | | |
NCT04539548: A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract |
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| Completed | 3 | 65 | US | Dextenza Ophthalmic Insert, DEXTENZA, Prednisolone acetate ophthalmic suspension USP 1% | Ocular Therapeutix, Inc. | Cataract | 12/23 | 12/23 | | |
2022-000624-37: Clinical trial to assess the safety and efficacy of Clobetasol propionate ophthalmic nanoemulsion 0.05% compared to Prednisolone acetate, 1% in the treatment of inflammation after cataract surgery in pediatric population 0 to 3 years of age. Ensayo clínico para evaluar la seguridad y eficacia de clobetasol propionato 0,05% nanoemulsión oftálmica en comparación con acetato de prednisolona 1% en el tratamiento de la inflamación después de la cirugía de cataratas en población pediátrica de 0 a 3 años. |
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| Not yet recruiting | 3 | 60 | Europe | Clobetasol propionate ophthalmic nanoemulsion, 0.05%, Clobetasol propionate, Ear/eye drops, solution, Ear/eye drops, suspension, Pred Forte 10 mg/ml colirio en suspensión | Laboratorios Salvat, S.A., Laboratorios Salvat, S.A. | Inflammation and pain associated with ocular surgery. Inflamación y dolor después de la cirugía de cataratas., Inflammation and pain associated with ocular surgery. Inflamación y dolor después de la cirugía de cataratas., Diseases [C] - Eye Diseases [C11] | | | | |
NCT05147233: OCS-01: A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery |
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| Recruiting | 3 | 240 | US | Dexamethasone, OCS-01, Vehicle Placebo, Placebo | Oculis | Disorders of the Eye Following Cataract Surgery | 03/23 | 06/23 | | |
NCT05528172: A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery |
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| Completed | 3 | 331 | US | Ripasudil, K-321, Placebo | Kowa Research Institute, Inc. | Corneal Edema After Cataract Surgery | 06/23 | 06/23 | | |
OPTIMIZE-2, NCT06128369: Study Evaluating the Efficacy and Safety of OCS-01 Eye Drops in Subjects Following Cataract Surgery |
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| Recruiting | 3 | 160 | US | Dexamethasone Ophthalmic Suspension, OCS-01, Vehicle of OCS-01 | Oculis, ORA, Inc. | Inflammation Eye, Pain, Postoperative, Cataract | 07/24 | 12/24 | | |
NCT05826353: A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD) |
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| Recruiting | 3 | 100 | Europe, Canada, US | Ripasudil, K-321, Placebo | Kowa Research Institute, Inc. | Fuchs Endothelial Corneal Dystrophy | 06/24 | 01/25 | | |
NCT05550363: A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery (2) |
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| Withdrawn | 3 | 150 | NA | Dexycu, Placebo/Vehicle | EyePoint Pharmaceuticals, Inc. | Cataract | 09/23 | 09/23 | | |
NCT05550350: A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery |
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| Not yet recruiting | 3 | 150 | NA | Dexycu, Placebo/Vehicle | EyePoint Pharmaceuticals, Inc. | Cataract | 04/24 | 04/24 | | |
NCT06383273: A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR) |
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| Recruiting | 3 | 528 | US | MELT-300 sublingual tablet, Midalozam sublingual tablet, Placebo sublingual tablet | Melt Pharmaceuticals, MedTrials Incorporated, Evolution Research Group, Catalent, Pharmalex | Cataract | 12/24 | 01/25 | | |
CLOSE-3, NCT05724446: Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population |
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| Recruiting | 3 | 60 | Europe | Clobetasol Propionate, SVT-15473, Prednisolone acetate ophthalmic suspension, 1% | Salvat | Cataracts Infantile | 12/25 | 12/25 | | |
NCT06061718: Travoprost Intraocular Implant in Conjunction With Cataract Surgery |
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| Active, not recruiting | 3 | 60 | RoW | iDose TR, travoprost intraocular implant | Glaukos Corporation | Open Angle Glaucoma, Ocular Hypertension | 03/24 | 12/24 | | |
2008-004336-20: Azithromycin concentration into aqueous humor of patients undergoing cataract surgery, after 3 days of treatment by AZYTER ® Open randomised monocentre study with 2 groups of 15 patients |
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| Ongoing | 2 | 30 | Europe | AZYTER, AZYTER | Laboratoires Thea | Patient concerned by this trial are patients who will undergo a cataract surgery | | | | |
NCT06146881: Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in Indonesia |
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| Recruiting | 2 | 70 | RoW | Diquafosol sodium 3%, Sodium hyaluronate 0.1% | Indonesia University, Santen Pharmaceutical Co., Ltd. | Dry Eye Disease | 12/23 | 03/24 | | |
NCT04630158: Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP) |
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| Completed | 2 | 153 | Europe, Japan, US | SAF312 Placebo, Artificial tears, SAF312 | Novartis Pharmaceuticals | Chronic Ocular Pain | 06/23 | 06/23 | | |
NCT06164743: Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery |
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| Completed | 2 | 91 | US | VVN461 Ophthalmic Solution 1.0%, VVN461 Ophthalmic Solution 0.5%, Vehicle | VivaVision Biotech, Inc | Inflammation | 05/24 | 05/24 | | |
NCT06365762: The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract |
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| Completed | 1/2 | 111 | US | EDTA Ophthalmic Solution 2.6%, C-KAD 2.6%, EDTA Ophthalmic Solution 1.3%, C-KAD 1.3%, Saline Solution (Placebo), Software Saline | Livionex Inc. | Age Related Cataracts | 12/06 | 04/07 | | |
NCT04212078: Intracameral Levofloxacin (0.5%) vs Intracameral Cefuroxime |
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| Recruiting | 1/2 | 138 | RoW | Levofloxacin Ophthalmic, Cravit 0.5%, Cefuroxime, Zinacef | National University of Malaysia, Santen Pharmaceutical Co., Ltd. | Endophthalmitis Postoperative | 01/22 | 10/22 | | |
NCT05026632: NPI-002 Intravitreal Implant for the Delay of Cataract Progression |
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| Recruiting | 1/2 | 30 | RoW | NPI-002 Intravitreal Implant | Nacuity Pharmaceuticals, Inc. | Cataract | 10/24 | 02/25 | | |
Tigris, NCT06120842: Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution |
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| Recruiting | 1/2 | 140 | US | Bimatoprost Implant System (High Dose), Bimatoprost Implant System (Low Dose), Timolol Maleate Ophthalmic Solution, 0.5%, Commercially Available Aspheric Monofocal Non-Yellow Chromophore IOL, SpyGlass IOL | SpyGlass Pharma, Inc. | Cataract, Glaucoma, Ocular Hypertension | | | | |
NCT05587205: Study to Assess Safety and Tolerability of EO2002 |
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| Recruiting | 1 | 32 | RoW | EO2002, Magnetic Human Corneal Endothelial Cells, Sham injection | Asociación para Evitar la Ceguera en México, Emmecell | Cataract, Endothelial Cell Loss, Corneal | 07/25 | 12/25 | | |
NCT05441930: A Study of Levofloxacin Ocular Implant in Patients Undergoing Routine Bilateral Cataract Surgery |
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| Withdrawn | 1 | 12 | US, RoW | Levofloxacin Ocular Implant, Control | PolyActiva Pty Ltd | Cataract | 12/23 | 03/24 | | |
| Recruiting | N/A | 1000000 | RoW | spectacles | Shanghai Eye Disease Prevention and Treatment Center, Brien Holden Vision | Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging | 11/19 | 11/26 | | |
| Completed | N/A | 250 | Europe | CZM IOL, Competitor IOL | Carl Zeiss Meditec AG | Cataract | 10/20 | 02/21 | | |
| Completed | N/A | 32 | US | Vivity ACRYSOF IQ IOL Group, ACRYSOF IQ IOL Control Group | John Berdahl, MD, Alcon Research, The Eye Associates, Eye Care Specialists, NewsomeEye | Cataract | 04/21 | 04/21 | | |
NCT01841450: Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery |
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| Active, not recruiting | N/A | 360 | US | iStent, GTS100, Cataract surgery | Glaukos Corporation | Primary Open Angle Glaucoma | 08/21 | 11/21 | | |
NCT03179397: Clinical Trial to Evaluate the Model SC9 IOL Compared to the Model LI61SE IOL (Bausch & Lomb) |
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| Terminated | N/A | 338 | US | Model SC9, Model LI61SE | CORD, LLC | Cataract | 10/21 | 07/23 | | |
NCT06533995: The Usefulness of Visuprime in Cataract Surgery |
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| Completed | N/A | 75 | Europe | Visuprime, Placebo | VISUfarma SpA | Cataract | 02/22 | 02/22 | | |
| Completed | N/A | 273 | Europe | OVD | Carl Zeiss Meditec AG | Cataract Senile | 11/21 | 02/22 | | |
Z8_CCI, NCT04082273: Comparison of Femto-laser and Manually Created Clear Corneal Incisions During Cataract Surgery |
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| Recruiting | N/A | 94 | Europe | Femtosecond Laser for Cataract Surgery, Conventional Cataract Surgery | Ziemer Ophthalmic Systems AG | Cataract | 11/21 | 12/21 | | |
FUSION, NCT03861351: Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant |
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| Completed | N/A | 58 | Europe | Mini WELL Toric Ready intraocular lens | SIFI SpA | Bilateral Cataract, Astigmatism | 11/21 | 11/21 | | |
| Completed | N/A | 36 | US | CALLISTO eye, Wavetec AnalyzOR | Chesapeake Eyecare and Laser Center, LLC, Carl Zeiss Meditec, Inc. | Cataract | 07/23 | 07/23 | | |
NCT04698278: Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery |
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| Recruiting | N/A | 20 | US | PanOptix Trifocal Intraocular Lens | Parkhurst NuVision Clinical Research LLC, Alcon Research | Cataract, Refractive Errors | 01/22 | 07/22 | | |
DECS-TW, NCT05096546: The Proportion of Patients Diagnosed With Dry Eye by the Asia Dry Eye Society (ADES) Criteria in Taiwan |
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| Active, not recruiting | N/A | 540 | RoW | No intervention | Far Eastern Memorial Hospital, Santen Pharmaceutical (Taiwan) Co., LTD, Kaohsiung Medical University, Taipei Veterans General Hospital, Taiwan | Dry Eye Syndromes | 02/22 | 07/22 | | |
NCT06567834: Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs |
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| Completed | N/A | 60 | US | Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150), Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150) | Empire Eye and Laser Center, Johnson & Johnson Surgical Vision, Inc. | Cataract, Presbyopia | 03/23 | 03/23 | | |
ZEPTO, NCT04882189: Study of Endothelial Cell Condition After Cataract Surgery Performed Using Capsulorhexis or |
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| Recruiting | N/A | 80 | US | Imaging | Centricity Vision, Inc. | Endothelial Cell Density Loss | 03/22 | 05/22 | | |
NCT06196593: Visual Outcomes Following Bilateral Implantation of the Vivity Toric Intraocular Lens |
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| Completed | N/A | 30 | RoW | AcrySof™ IQ Vivity™ Toric intraocular lens | LEC Eye Centre, Alcon Research | Cataract Senile, Intraocular Lens Complication | 04/23 | 04/23 | | |
| Completed | N/A | 25 | RoW | Trifocal Preloaded IOL Delivery System, Asqelio Trifocal, TFPIO130Y, TFLIO130, aspicio Trifocal, PTF60Y, TF60 | ICARES Medicus, Inc., AST Products, Inc. | Cataract | 04/22 | 08/23 | | |
NCT05776446: Clinical Behavior of the Asqelio™ Trifocal Diffractive Intraocular Lens |
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| Completed | N/A | 25 | Europe | | AST Products, Inc. | Cataract | 06/22 | 09/22 | | |
NCT05739656: Evaluation of Visual Acuity of the Envista One-piece Acrylic Toric IOL MX60ET |
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| Completed | N/A | 100 | US | CATARACT SURGERY, The enVista One-Piece Hydrophobic Acrylic Toric IOL | Bausch & Lomb Incorporated | Astigmatism | 07/22 | 07/22 | | |
| Recruiting | N/A | 50 | Europe | intraocular lens implantation in cataract surgery | Cristalens Industrie | Cataract | 03/26 | 07/26 | | |
| Completed | N/A | 30 | Europe | | AST Products, Inc. | Cataract Senile | 07/22 | 07/22 | | |
NCT04005651: Safety and Efficacy of a Trifocal Intraocular Lens (IOL) POD L GF in Comparison With a Multifocal and a Monofocal IOL |
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| Completed | N/A | 100 | Europe | POD L GF IOL, Symfony® IOL, AcrySof® IOL | Beaver-Visitec International, Inc. | Aphakia, Postcataract, Cataract; Eye Disease | 07/22 | 11/22 | | |
| Completed | N/A | 387 | Europe | Intraocular lens | Carl Zeiss Meditec AG | Cataract Senile | 08/22 | 12/22 | | |
NCT04755231: Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population |
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| Completed | N/A | 181 | RoW | AcrySof IQ PanOptix Presbyopia Correcting IOL, Model TFNT00, Cataract surgery | Alcon Research | Aphakia, Presbyopia | 08/22 | 03/23 | | |
PROMIR, NCT05146310: Prospective, Multicenter, Non-comparative Clinical Investigation to Support Safety & Effectiveness of I.SPACE® |
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| Completed | N/A | 81 | Europe | I.SPACE® | Laboratoires Vivacy, International Clinical Trials Association, Inferential | Cataract | 03/23 | 03/23 | | |
NCT04761276: Evaluation of Efficacy and Long-term Safety for Lucidis Instant Focus© - PMCF Study Protocol |
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| Recruiting | N/A | 120 | Europe | Surgical implantation of intra ocular lens | SAV-IOL SA, CEISO | Cataract | 10/22 | 10/22 | | |
NCT06229756: Clinical Results of Asqelio™ EDOF Toric Soft Hydrophobic Intraocular Lens After Cataract Surgery |
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| Active, not recruiting | N/A | 30 | Europe | | AST Products, Inc. | Cataract | 03/24 | 04/24 | | |
NCT05129566: Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm |
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| Completed | N/A | 78 | RoW | IOL Clareon AutonoMe, IOL Hoya iSert 251 | The S.N. Fyodorov Eye Microsurgery State Institution, Alcon Research | Cataract Senile, Myopia, High-Grade, Corneal Astigmatism | 12/22 | 04/24 | | |
NCT06062771: Efficacy and Safety of the Use of Ophthalmic Viscosurgical Devices (OVD) FIDIAL PLUS vs IAL®-F During Cataract Surgery |
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| Completed | N/A | 50 | Europe | FIDIAL PLUS, IAL®-F | Fidia Farmaceutici s.p.a. | Cataract | 11/22 | 01/23 | | |
NCT06190925: Clinical Results of Asqelio Trifocal Toric Diffractive Intraocular Lens |
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| Completed | N/A | 30 | Europe | | AST Products, Inc. | Cataract | 11/23 | 12/23 | | |
NCT03844828: Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes |
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| Active, not recruiting | N/A | 100 | RoW | IOL implantation experimental, POD FT IOL implantation | Beaver-Visitec International, Inc. | Cataract, Lens Opacities, Presbyopia | 11/22 | 12/24 | | |
NCT04866706: Performance and Safety of Routine Cataract Surgery With Visiol |
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| Completed | N/A | 100 | RoW | Visiol, Sodium hyaluronate | TRB Chemedica | Following Cataract Surgery | 12/22 | 10/23 | | |
NCT05377515: Evaluation of Visual Outcomes in Patients With Complex Corneas Implanted With the IC-8 IOL |
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| Completed | N/A | 21 | RoW | | AcuFocus, Inc. | Cataract, Presbyopia, Irregular; Contour of Cornea | 12/22 | 12/22 | | |
| Recruiting | N/A | 1000 | RoW | Blood sampling for Cholestanol Analysis | TRPHARM, Klinar CRO, Düzen Laboratories Group | Cerebrotendinous Xanthomatosis | 12/22 | 03/23 | | |
NCT03584958: Comparing Refractive and Visual Outcomes of MIGS and Traditional Surgeries |
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| Enrolling by invitation | N/A | 150 | US | | Wills Eye, Allergan, The American Society of Cataract and Refractive Surgery Foundation | Glaucoma, Ocular Hypertension | 12/22 | 06/23 | | |
NCT05783583: A Comparison of the Diagnostic Confidence and Image Quality Between the Eyoto Theia (RDSL) and a Predicate Device. |
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| Completed | N/A | 49 | US | Remote Digital Slit Lamp | Eyoto Group Ltd | Cataract | 01/23 | 01/23 | | |
NCT05504343: Assessing The Visual Performance Of Hanita Lenses "Intensity SL" Intraocular Lens |
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| Completed | N/A | 20 | RoW | "Intensity SL" Intraocular Lens | Hanita Lenses | Cataract | 01/23 | 01/23 | | |
NCT05056233: Systane Hydration in Subjects Undergoing Cataract Surgery |
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| Completed | N/A | 35 | Europe | Systane Hydration lubricant eye drops, Systane Hydration® Ophthalmic Solution | Alcon Research | Dry Eye Disease, Cataract | 01/23 | 01/23 | | |
| Completed | N/A | 28 | Europe | IOL implantation experimental | Beaver-Visitec International, Inc., targomedGmbH | Cataract, Lens Opacities, Astigmatism | 06/23 | 03/24 | | |
NCT04890249: Clinical Investigation of Two Tecnis Investigational Lenses |
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| Completed | N/A | 221 | RoW | Investigational IOL Model C1V000, Investigational IOL Model C2V000, Control IOL Model ICB00 | Johnson & Johnson Surgical Vision, Inc. | Cataract, Corneal Astigmatism | 01/23 | 01/23 | | |
NCT05735990: Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia |
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| Completed | N/A | 21 | Europe | Intraocular lens | Medicontur Medical Engineering Ltd | Cataract, Presbyopia, Hyperopia, Myopia, Pseudophakia | 01/23 | 01/23 | | |
| Completed | N/A | 76 | Europe | IOL implantation experimental | Beaver-Visitec International, Inc., targomedGmbH | Cataract, Lens Opacities, Astigmatism | 07/23 | 04/24 | | |
| Active, not recruiting | N/A | 244 | Europe, RoW | IOL implantation experimental (Isopure 1.2.3.), IOL implantation active comparator (Micropure 1.2.3.) | Beaver-Visitec International, Inc., targomedGmbH | Cataract, Lens Opacities | 02/23 | 06/24 | | |
PHY2107, NCT05255029: Clinical Investigation of a Monofocal Toric Intra Ocular Lens (IOL) in Cataractous Eyes |
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| Completed | N/A | 42 | Japan | POD T 49P implantation experimental | Beaver-Visitec International, Inc. | Cataract, Lens Opacities, Astigmatism | 02/23 | 02/23 | | |
BioBase, NCT05458661: Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort |
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| Not yet recruiting | N/A | 100 | NA | Clinical Prototype BioBase (SN 07 and SN 08), IOLMaster 700 Vs. 1.90 (Carl Zeiss Meditec AG, Göschwitzer Straße 51-52, 07745 Jena), Pentacam HR (Oculus Optikgeräte GmbH, Münchholzhäuser Straße 29, 35582 Wetzlar), MS-39 (bon Optic Vertriebsges. mbH, Stellmacherstraße 14, 23556 Lübeck) | Carl Zeiss Meditec AG | Cataract, Lens Opacities, Artificial Lens Implant, Corneal Astigmatism, Corneal Defect, Corneal Deformity | 03/23 | 03/23 | | |
NCT05346172: The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction |
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| Completed | N/A | 60 | US | PanOptix or PanOptix Toric IOL | Research Insight LLC | Cataract | 03/23 | 03/23 | | |
NCT06247683: Study to Confirm Safety and Performance of a New Multifocal IOL |
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| Active, not recruiting | N/A | 135 | Europe, RoW | trifocal intraocular lens | Carl Zeiss Meditec AG | Cataract Senile | 03/24 | 01/25 | | |
NCT03970525: Venturi and Peristaltic Based Phacoemulsification in Femtosecond Laser Cataract Surgery |
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| Completed | N/A | 111 | US | Venturi pump, Peristaltic vacuum pump | Wendell Scott, Johnson & Johnson Surgical Vision, Inc. | Cataract Senile | 03/23 | 03/23 | | |
OVD PMCF, NCT05832749: Comparison of the Safety and Efficacy of Ophtesis Bio 3% With a Similar 3% Sodium Hyaluronate OVD |
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| Recruiting | N/A | 296 | RoW | Ophtesis Bio 3% ophthalmic viscosurgical device, Healon Endocoat 3% ophthalmic viscosurgical device | Gemini Eye Clinic | Bilateral Cataract, Unilateral Cataract | 04/23 | 05/23 | | |
NCT05141370: Assessment of a Femtosecond Laser to Perform Capsulorhexis During Cataract Surgery |
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| Completed | N/A | 83 | Europe | cataract surgery with CATSYS | Ilasis Laser | Cataract Surgery | 04/23 | 04/23 | | |
| Completed | N/A | 54 | US | CyPass Micro-Stent, CyPass® Micro-Stent, Model 241-S, Cataract Surgery | Alcon Research | Primary Open Angle Glaucoma, Cataract | 04/23 | 04/23 | | |
NCT05396599: A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens. |
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| Terminated | N/A | 35 | US | Model DIU, Model DFW, Model ZCT | Johnson & Johnson Surgical Vision, Inc. | Cataract | 04/23 | 04/23 | | |
NCT06469541: Clinical Outcomes After Implantation of a Monofocal Hydrophobic IOL, Bi-Flex 877PAY With POB-MA Preloaded Injector |
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| Completed | N/A | 100 | Europe | | Medicontur Medical Engineering Ltd | Cataract | 07/23 | 12/23 | | |
ARCUATAS, NCT05053620: Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration |
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| Completed | N/A | 22 | Europe | Calculation of the arcuate intrasomal incisions | OFTALVIST (Oftalmología Vistahermosa S.L), Johnson & Johnson Surgical Vision, Inc. | Cataract, Astigmatism | 04/23 | 04/23 | | |
NCT05089474: A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients With Open-Angle Glaucoma |
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| Completed | N/A | 45 | RoW | Streamline Surgical System | New World Medical, Inc. | Open Angle Glaucoma | 04/23 | 04/23 | | |
| Completed | N/A | 73 | Europe | IOL implantation experimental (ISOPURE 1.2.3.), IOL implantation active comparator (Acrysof Vivity) | Beaver-Visitec International, Inc., targomedGmbH | Cataract, Lens Opacities | 08/23 | 08/23 | | |
NCT05729477: A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device |
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| Enrolling by invitation | N/A | 375 | US | miCOR System, Phaco Subject Cohort | Carl Zeiss Meditec, Inc. | Cataract Surgery | 10/24 | 10/24 | | |
NCT03603600: Evaluate the Safety and Effectiveness of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens |
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| Completed | N/A | 501 | US | enVista MX60E, enVista MX60EF | Bausch & Lomb Incorporated | Cataract | 05/23 | 05/23 | | |
NCT06578910: Retrospective, Non-interventional Clinical Investigation of the Safety and Performance of 640AD Monofocal Intraocular Lens |
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| Completed | N/A | 80 | Europe | Standard of care, Patient satisfaction questionnare | Medicontur Medical Engineering Ltd | Cataract, Pseudophakia | 04/24 | 04/24 | | |
NCT05065749: Clinical Results of Asqelio Trifocal Diffractive Intraocular Lens |
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| Active, not recruiting | N/A | 30 | Europe | | AST Products, Inc. | Cataract | 06/23 | 09/23 | | |
NCT04971863: In-vivo Behavior of Asqelio Monofocal Biaspheric Intraocular Lens |
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| Completed | N/A | 200 | Europe | | AST Products, Inc., Hospital Universitario La Fe | Cataract, Intraocular Lens Complication | 10/23 | 01/24 | | |
NCT05750225: Clinical Investigation of the Safety and Performance of Model 690AD and Model 690ADY Monofocal Intraocular Lens Implantation |
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| Completed | N/A | 52 | Europe | Standard of care, Patient satisfaction questionnare | Medicontur Medical Engineering Ltd | Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification | 06/23 | 06/23 | | |
NCT04750447: Safety and Efficacy of an Ab Interno Gelatin Stent (XEN63) With or Without Mitomycin C |
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| Recruiting | N/A | 30 | Canada | XEN 63 | Prism Eye Institute, Allergan | Glaucoma, Open-Angle | 06/23 | 06/23 | | |