| Tekturna (aliskiren) / PDL |
ALTO, NCT00542269 / 2007-003677-10: Efficacy and Safety of Aliskiren/Ramipril/Amlodipine Compared With Ramipril/Amlodipine and Aliskiren/Amlodipine in Patients With Metabolic Syndrome |
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| Terminated | 4 | 178 | Europe | Amlodipine, Aliskiren, Ramipril | Novartis | Hypertension With Metabolic Syndrome | 07/09 | 07/09 | | |
NCT00660309: A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus |
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| Completed | 4 | 45 | US | Aliskiren, SPP100, Irbesartan, Captopril | Novartis | Type 2 Diabetes Mellitus | 12/09 | 12/09 | | |
AIMS, NCT00797316: Aliskiren Plus HCTZ Compared to Aliskiren in Metabolic Syndrome Patients With Stage 2 Systolic Hypertension |
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| Completed | 4 | 532 | US | Aliskiren, Hydrochlorothiazide | Novartis | Hypertension | 12/09 | 12/09 | | |
ASTRIDE, NCT00787605: Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus |
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| Completed | 4 | 860 | US | Amlodipine, Hydrochlorothiazide (HCTZ), Aliskiren | Novartis | Hypertension, Diabetes Mellitus | 01/10 | 01/10 | | |
NCT00818779: Direct Renin Inhibition Effects on Atherosclerotic Biomarkers |
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| Completed | 4 | 38 | US | Aliskiren, Tekturna, Amlodipine, Norvasc | Texas Tech University Health Sciences Center | Coronary Artery Disease, Type 2 Diabetes Mellitus | 08/11 | 08/11 | | |
ViVID, NCT00927394: Aliskiren and Valsartan vs Valsartan Alone in Patients With Stage II Systolic Hypertension and Type II Diabetes Mellitus |
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| Completed | 4 | 1143 | US | Aliskiren, Valsartan, Placebo for Aliskiren, Placebo for Valsartan | Novartis | Hypertension | 10/11 | 10/11 | | |
| Completed | 4 | 32 | Europe | Aliskiren, Brand name: Ralisez, ATC-code: C09XA02, Moxonidine, No brand name (generic product), ATC-code: C02AC05, Hydrochlorothiazide, ATC-code: C03AA03, Placebo (for aliskiren), Placebo (for moxonidine and hydrochlorothiazide) | UMC Utrecht, Novartis Pharmaceuticals | Hypertension, Abdominal Obesity, Metabolic Syndrome | 02/12 | 02/12 | | |
NCT00994253: Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II Diabetics |
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| Withdrawn | 4 | 0 | US | Aliskiren, Tekturna, Hydrochlorothiazide, HCTZ | William Beaumont Hospitals, Novartis Pharmaceuticals | Hypertension, Diabetes Type 2 | 12/12 | 12/12 | | |
NCT01409408: Comparison of Amlodipine and Aliskiren in Diabetic Hypertensive Patient With Blood Pressure Not Controlled by Losartan |
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| Withdrawn | 4 | 0 | RoW | Aliskiren, Rasilez., Amlodipine, Norvasc. | Hospital Universitario Pedro Ernesto, Novartis | Hypertension, Diabetes Mellitus | 04/13 | 12/13 | | |
| Completed | 4 | 237 | Japan | Aliskiren, any angiotensin receptor blockers | Shiga University | Type 2 Diabetes Mellitus, Hypertension | 08/14 | 12/14 | | |
