Bipolar Disorder |
ACTRN12623000354684: Brains, Babies & Bodies: A group psychological intervention for pregnant women living with bipolar disorder – a pilot feasibility and acceptability study |
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| Not yet recruiting | N/A | 10 | | | Western Sydney University, Western Sydney University | Bipolar Disorder | | | | |
ACTRN12624001098527: 'Hearing Voices that are Distressing' (HVD) simulation workshop for regional (and rural) health and mental health workers practising in the health sector using a clinical trial (CT) leveraging from the regional Teletrial cluster model (National Australian Teletrial Program -ATP-SA) to build a higher level of evidence for lived experience (LE) added-value in simulation methods used for education and training for workers (and students). |
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| Not yet recruiting | N/A | 90 | | | The University of South Australia Department of Rural Health, The University of South Australia Department of Rural Health, Australian Teletrial Program | Auditory Hallucinations
, Hearing Distressing Voices , Schizophrenia, Bipolar disorder | | | | |
| Not yet recruiting | N/A | 100 | | | James Cook University, Baszucki Family Foundation | Schizophrenia, Bipolar disorder | | | | |
ACTRN12623001272684: Evaluating the use of digitally enhanced treatment models in early intervention for youth with bipolar disorder. |
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| Not yet recruiting | N/A | 125 | | | Orygen, National Health and Medical Research Council, VIC Department of Health, Orygen | Bipolar Disorder | | | | |
ACTRN12622001238763: A UK Biobank analysis to assess the outcomes of frailty in people with severe mental illness |
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| Not yet recruiting | N/A | 500000 | | | The University of Queensland, The University of Queensland (UQ) Academy of Psychiatry top-up research funds | frailty, schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, multimorbidity, mortality | | | | |
ACTRN12622000679785: The PROSPECT project (PROmoting Sexual health in young PEople with mental ill-health): Clinical feasibility Trial |
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| Recruiting | N/A | 40 | | | Orygen , Department of Health | first episode of psychosis , borderline personality disorder, depression, non-psychotic bipolar disorder, anxiety, sexual health, sexually transmitted infections | | | | |
ACTRN12622001026718: Evaluating the effectiveness of a comprehensive lifestyle therapy program versus psychological care for managing mood disorders: The HARMON-E Trial |
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| Recruiting | N/A | 378 | | | Deakin University, National Health and Medical Research Council’s Medical Research Future Fund Million Minds Mission – 2020 Mental Health Research | Major depressive disorder, Bipolar affective disorder | | | | |
| Recruiting | N/A | 40 | | | University of Otago, Canterbury Medical Research Foundation | Major depressive disorder, Bipolar disorder | | | | |
ACTRN12623001118695: The feasibility and preliminary effectiveness of exercise therapy in transdiagnostic mental health services. |
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| Recruiting | N/A | 50 | | | The University of Western Australia, The University of Western Australia, Fremantle Hospital Mental Health Service | Severe mental illness, Psychotic Disorders, Bipolar Disorders, Personality Disorders, Anxiety Disorders, Depressive Disorders, Psychosis | | | | |
ACTRN12624000195550: A hybrid randomised controlled feasibility pilot trial of a self-management intervention “My Personal REcovery Plan” (MyPREP) for people with long term mental health conditions: The MyPREP Trial |
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| Recruiting | N/A | 40 | | | The University of Sydney, The University of Sydney (The Moyira Elizabeth Vine Grant for Research) | Schizophrenia, Schizophrenia-related Disorders, Bipolar Disorder, Major Depressive Disorder, Post-Traumatic Stress Disorder, Complex Post-Traumatic Stress Disorder, Personality Disorder | | | | |
| Recruiting | N/A | 60 | | Repetitive Transcranial Magnetic Stimulation for three weeks versus An inactive Sham coil | Tai Po Hospital, CUHK; Department of Psychiatry, The Chinese University of Hong Kong, Food and Health Bureau | Bipolar Depression | | | | |
| Enrolling by invitation | N/A | 600 | Europe | | Österreichische Gesellschaft für Bipolare Erkrankungen | Bipolar Disorder | 01/08 | 12/14 | | |
ChiCTR-OCH-13005058: A comparation research of prospective memory on schizophrenia and bipolar disorder |
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| Recruiting | N/A | 120 | | N/A | the First Affiliated Hospital of Kunming Medical University; None, the First Affiliated Hospital of Kunming Medical University | Schizophrenia, Bipolar disorder | | | | |
ChiCTR-TRC-14004452: The efficacy and safety of Paliperidone Extended-Release Tablets combined with sodium valproate in Bipolar disorder manic episode |
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| Recruiting | N/A | 200 | | PANSS ;Paliperidone Extended-Release Tablets combined with placebo ;Paliperidone Extended-Release Tablets combined with sodium valproate | First Affiliated Hospital, College of Medicine, Zhejiang University; First Affiliated Hospital, College of Medicine, Zhejiang University, National Natural Science Foundation (81301158) | Bipolar disorder | | | | |
NCT06581822: Biomarkers for Pharmacoresponse in Bipolar Disorder - Coagulation |
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| Active, not recruiting | N/A | 68 | NA | | Karolinska Institutet | Bipolar Disorder | 10/24 | 04/25 | | |
ChiCTR-IOR-17012449: Psychoeducation for psychiatric inpatients following remission of a manic episode in bipolar I disorder: A randomized controlled trial |
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| Completed | N/A | 150 | | pharmacological treatment and group-based psychoeducation ;pharmacological treatment and combined regular free discussions | Beijing Anding hospital; Beijing Municipal Science & Technology Committee, Beijing Municipal Science &Technology Commission | Bipolar disorder | | | | |
ChiCTR-COC-17011401: A study of gut microbiota, immunology, Imageology in patients with bipolar disorder |
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| Recruiting | N/A | 200 | | quetiapine monotherapy | First Affiliated Hospital, Zhejiang University School of Medicine; First Affiliated Hospital, Zhejiang University School of Medicine, Provincial Natural Science Foundation | Bipolar disorder | | | | |
NCT02095483: Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder-Not Otherwise Specified |
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| Recruiting | N/A | 40 | US | Mindfulness Group Therapy Study | Stanford University | Bipolar Disorder | 01/18 | 01/19 | | |
| Completed | N/A | 385 | Europe | Fibroscan, Blood sample | Centre Hospitalier Esquirol | Severe Bipolar I Disorder (Diagnosis), Bipolar I Disorder, Most Recent Episode Mixed, in Remission, Depression Psychotic Feature, Mood-Incongruent Delusion | 02/18 | 07/21 | | |
| Active, not recruiting | N/A | 32881 | RoW | Patient with schizophrenia without intervention | Ningbo University, The Affiliated Kangning Hospital of Ningbo University | Schizophrenia | 12/23 | 12/26 | | |
NCT02663349: Skills Training to Enhance Vocational Outcomes in Veterans With Serious Mental Illness |
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| Completed | N/A | 22 | US | Social Cognition and Intervention Training | Minneapolis Veterans Affairs Medical Center, Minnesota Veterans Medical Research and Education Foundation | Schizophrenia, Bipolar Disorder, Psychotic Disorders | 10/18 | 07/19 | | |
DYSBIP, NCT06167577: Dysbindin-antipsychotics Psychophamarcogenetics: a Mouse-human Translational Study Towards Personalized Healthcare in Bipolar Disorders |
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| Completed | N/A | 150 | Europe | | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, ASST Santi Paolo e Carlo, ASST Melegnano e Martesana, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | Bipolar Disorder | 02/22 | 11/23 | | |
ChiCTR-INR-16008179: Efficacy Study of tDCS and Mindfulness on Cognitive Function of Affective Disorder |
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| Not yet recruiting | N/A | 64 | | tDCS 12 sessions (2mA, 20 minutes, F3 anodal, F4 cathodal) over 4 weeks+ simultaneous mindfulness practices ;tDCS 12 sessions (2mA, 20 minutes, F3 anodal, F4 cathodal) over 6 weeks | Department of Health, Taipei City Government; Level of the institution:, Department of Health, Taipei City Government | Major Depressive Disorder and Bipolar Disorder | | | | |
| Not yet recruiting | N/A | 200 | | non ;non ;non ;non | The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital); Guangzhou Huiai Hospital, project funds | depression、bipolar disorder、schizophrenia | | | | |
ChiCTR-DOC-16010081: A diagnostic panel for common psychiatric disorders: a cohort study based on serum protein levels |
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| Unknown status | N/A | | | | Department of Psychosomatics and Psychiatry, Zhongda Hospital, School of Medicine, Southeast University; Zhongda Hospital, School of Medicine, Southeast University, National Natural Science Foundation of China (No. 81071101, 81571330 Yonggui Yuan, 81301167 Zhi Xu), Fundamental Research Funds for the Central Universities (Southeast University, No. 2242016K41053) | mental disorders (include schizophrenia, major depressive disorder, bipolar mania, bipolar depression and panic disorder ) | | | | |
ChiCTR1800018599: Bioequivalence study of Risperidone in patients with schizophrenia or bipolar I disorder |
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| Not yet recruiting | N/A | 24 | | Risperidone Long-acting intramuscular injection of Qilu Pharmaceuticals Co. Ltd. ;RISPERDAL CONSTA? (Risperidone) LONG-ACTING INJECTION of Janssen Pharmaceuticals | Qilu Pharmaceutical Co., Ltd/CBCC Global Research LLP India; Qilu Pharmaceutical Co., Ltd, Qilu Pharmaceutical Co.,Ltd | Schizophrenia or Bipolar I Disorder | | | | |
ChiCTR1800019064: Identification of chronic non-communicable diseases in the concept of stress-rhythm disorder and their optimize therapeutic scheme |
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| Not yet recruiting | N/A | 800 | | None | Department of Psychology, West China Hospital, Sichuan University; West China Hodpital, Sichuan University, Postgraduate Funding and Western China Psychiatric Association | Bipolar Disorder, diabetes, ulcer, IBS, etc | | | | |
ChiCTR-ROC-17013029: The comparison of intestinal flora species and metabolites in Chinese patients with schizophrenia, depression and bipolar disorder |
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| Completed | N/A | 400 | | without ;without ;without ;without | The department of psychiatry, Xijing Hospital; Xijing Hospital, From the department of psychiatry | schizophrenia, depression, bipolar disorder | | | | |
ChiCTR-INR-17013338: A randomized, double-blind, sham-controlled study of deep-brain magnetic stimulation (DMS) in the treatment of bipolar depression |
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| Recruiting | N/A | 60 | | Patients in this arm will receive 14 days of active DMS, twice a day. ;Patients in this arm will receive 14 days of sham stimulation, twice a day. | Beijing Anding Hospital, Capital Medical University; The National Clinical Research Center for Mental Disorders, Beijing Anding Hospital Capital Medical University, Beijing Municipal Administration of Hospitals Incubating Program, Code:PX2017048 | bipolar disorder | | | | |
ChiCTR1800015504: Pioglitazone adjuntive therapy for bipolar depression: the efficacy and potential mechanisms |
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| Recruiting | N/A | 90 | | pioglitazone adjuntive therapy ;blank control | Peking University Sixth Hospital; Peking University Sixth Hospital, the National Natural Science Foundation of China | Bipolar Disorder | | | | |
ChiCTR1900022563: Finding bio-imaging diagnosis to distinguish bipolar disorder form major depressive disorder: a study using fNIRS |
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| Recruiting | N/A | 270 | | Nil ;Nil ;Nil | Yuquan Hospital, Tsinghua University; Yuquan Hospital, Tsinghua University, Capital clinical application research | Major Dpressive Disorder and Bipolar disorder | | | | |
NCT04191876: Financial Incentives to Improve Medication Adherence |
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| Completed | N/A | 25 | US | Wellth - Financial Incentives | Northwell Health | Schizophrenia, Schizo Affective Disorder, Bipolar Disorder, Depression | 05/20 | 03/22 | | |
ChiCTR1900027283: Screening of sleep disorders in patients with mental disorders in Beijing |
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| Recruiting | N/A | 2100 | | nil | Peking University Sixth Hospital; Peking University Sixth Hospital, nil | schizophrenia, depression and bipolar disorder | | | | |
ChiCTR1900028041: Development of Video Game Therapy System Based on Personalized Evaluation and Exploration of Brain Mechanism for Promoting Mental Rehabilitation |
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| Recruiting | N/A | 60 | | Game Therapy ;Control Group | West China Hospital, Sichuan University; Mental Health Center, West China Hospital, Sichuan University, Science and Technology Department of Sichuan Province | Schizophrenia and Bipolar Disorder | | | | |
| Completed | N/A | 144 | Europe | Mindfulness Based Cognitive Therapy, MBCT, Mindfulness training, Usual Care | Radboud University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development, Pro Persona, Altrecht, Dimence, PsyQ | Bipolar Disorder | 06/20 | 06/21 | | |
ChiCTR-INR-17013250: Light Therapy in Patients With Bipolar Depression: A Randomized Controlled Study |
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| Recruiting | N/A | 198 | | Bright Light Therapy Combined With Mood Stabilizers ;dim Red Light Therapy Combined With Mood Stabilizers | Peking University Sixth Hospital (Peking University Institute of Mental Health); Peking University Sixth Hospital, Beijing Municipal Science &Technology Commission, the Capital Characteristic of Clinical Application Research, project number: Z171100001017086 | Bipolar Disorder | | | | |
NCT06369792: PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH DEPRESSION |
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| Recruiting | N/A | 200 | Europe | | Les Toises - Psychiatry and Psychotherapy Center | Depressive Disorder, Bipolar Disorder, Bipolar Depression | 12/24 | 12/24 | | |
| Completed | N/A | 1419 | Europe | ≥ 1 potential risk factor for BD, depressive syndrome, ADHD | Technische Universität Dresden, German Federal Ministry of Education and Research, Charite University, Berlin, Germany, Ruhr University of Bochum, Goethe University, Universitätsklinikum Hamburg-Eppendorf, Philipps University Marburg Medical Center, University Hospital Tuebingen, Vivantes Hospital am Urban, Berlin | Bipolar Disorder | 10/20 | 10/20 | | |
| Recruiting | N/A | 60 | Europe | ECo program, CRT program, Supportive psychotherapy | Centre hospitalier de Ville-Evrard, France | Bipolar Disorder | 12/24 | 12/24 | | |
ChiCTR1900027458: Single arm, open-label, multicenter clinical study for evaluation of efficacy and safety of adjunctive low-concentration sevoflurane in the treatment of hospitalized patients with bipolar disorder |
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| Recruiting | N/A | 25 | | Inhalation of sevoflurane | Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, National Natural Science Foundation of China (81671116 and 81870823) | bipolar disorder | | | | |
ChiCTR1900021088: A cohort study for sex hormone levels in child-bearing age women with bipolar mania |
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| Not yet recruiting | N/A | 240 | | oral lithium carbonate therapy ;Oral lithium carbonate treatment ;Oral valproic acid therapy ;No treatment | Zhengzhou Eighth People's Hospital (Zhengzhou Mental Health Center); Zhengzhou Eighth People's Hospital (Zhengzhou Mental Health Center), Henan Medical Science and Technology Research Program (No. 2018020866) | Bipolar Disorder | | | | |
ChiCTR2000029824: A multicenter randomized controlled clinical trial for evaluation of efficacy and safety of adjunctive low-concentration sevoflurane in the treatment of hospitalized patients with bipolar disorder |
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| Not yet recruiting | N/A | 75 | | antipsychotics+sevoflurane ;antipsychotics ;antipsychotics+MECT | Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, National Natural Science Foundation of China (81671116 and 81870823) | bipolar disorder | | | | |
ChiCTR2000031858: Based on a multi-disease sharing genetic research platform to explore the brain imaging and multi-omics mechanism of three common mental disorders before and after modified electroconvulsive therapy |
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| Not yet recruiting | N/A | 120 | | modified electroconvulsive therapy ;N/A | Institute of Mental Health, the Sixth Hospital of Peking University; Institute of Mental Health of Beijing University's Sixth Hospital, Peking University clinical scientist program (BMU2019LCKXJ012) | Schizophrenia, depression, bipolar disorder | | | | |
ChiCTR1900028059: To explore the peripheral blood markers of diagnosis and curative effect evaluation in bipolar disorder: an observational study |
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| Not yet recruiting | N/A | | | | Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangdong Province Natural Science Foundation (2018A030313427, 2017A030313490) | Bipolar disorder | | | | |
NCT04399070: The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) |
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| Not yet recruiting | N/A | 150 | RoW | S-ketamine, ketamine, saline | Yan Qiu | Depression, Bipolar, Depression, Unipolar, Major Depressive Disorder, Manic-Depressive - Now Depressed | 12/20 | 01/21 | | |
| Recruiting | N/A | 240 | | Brain imaging ;Brain imaging ;Brain imaging ;Brain imaging | Institute of Psychology, Chinese Academy of Sciences; Institute of Psychology, Chinese Academy of Sciences, National Natural Science Foundation of China (81571317, 31400884), Beijing Municipal Science and Technology Grants(Z151100000315020,Z161100000216138) | Major Depressive disorder, Bipolar Disorder, Schizophrenia | | | | |
NCT04024553: A Genetic Family Cohort Study of Bipolar Disorder in Chinese Han Population |
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| Enrolling by invitation | N/A | 2520 | RoW | | Shanghai Mental Health Center | Bipolar Disorder | 12/20 | 12/22 | | |
ChiCTR1900022812: Establishing clinical follow-up database and intelligent mobile disease management system for bipolar disorder |
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| Not yet recruiting | N/A | 100 | | Mobile management ;control | Peking University 6th Hospital; Peking University 6th Hospital, The capital health research and development of special | bipolar | | | | |
ChiCTR2000030675: rTMS in the occipital lobe based on fMRI navigation improves the cognitive function of euthymic bipolar disorder |
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| Recruiting | N/A | 80 | | S1 was used as the stimulus site, and 10 true stimuli were followed by 10 false stimuli ;S1 was used as the stimulus site, and 10 false stimuli were followed by 10 true stimuli ;S2 was used as the stimulus site, and 10 true stimuli were followed by 10 false stimuli ;S2 was used as the stimulus site, and 10 false stimuli were followed by 10 true stimuli | The First Affiliated Hospital, Zhejiang University School of Medicine; The First Affiliated Hospital, Zhejiang University School of Medicine, self-raised funds by researcher | bipolar disorder | | | | |
NCT03497663: VIA Family - Family Based Early Intervention Versus Treatment as Usual |
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| Completed | N/A | 96 | Europe | VIA Family intervention, Treatment As Usual, TAU | Mental Health Services in the Capital Region, Denmark, Municipality of Frederiksberg, Denmark, Ministry of the Interior and Health, Denmark, TrygFonden, Denmark | Early Intervention, Child of Impaired Parents, Child, Adolescent, Mental Disorders, Severe, Schizophrenia, Bipolar Disorder, Depressive Disorder, Recurrent, Psychotic Disorders, Parent-Child Relations | 01/21 | 01/21 | | |
ChiCTR2200061416: Near-infrared brain imaging of depression and bipolar depression disorder |
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| Completed | N/A | 80 | | Drug treatment ;None | Tsinghua University Yuquan Hospital; Tsinghua University Yuquan Hospital, self-raised | depression and bipolar depression disorder | | | | |
NCT04450147: Tai Chi/Qigong for Subsyndromal Depression and Cognition in Older Age Bipolar Disorder |
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| Recruiting | N/A | 50 | Canada | Tai Chi/Qigong vs. Walking/Stretching | Lady Davis Institute | Bipolar Disorder | 02/21 | 05/21 | | |
ChiCTR2000030182: Study on TPA, TPG axis hormone, CRP and p300 levels in unipolar and bipolar depression patients |
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| Recruiting | N/A | 90 | | N/A ;N/A ;N/A | Shandong Mental Health Center; Shandong Mental Health Center, Self-financing | Unipolar and bipolar depression | | | | |
ChiCTR2000032118: Effects of physical therapy on blood sample metabolomics and fecal intestinal flora in patients with mental illness |
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| Recruiting | N/A | 300 | | N/A ;N/A ;N/A | Chang'an Hospital; Chang'an Hospital, Self-funded by the department | schizophrenia;bipolar disorder;depressive disorder | | | | |
REMBAU, NCT02423499: Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder |
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| Recruiting | N/A | 90 | Europe | | University Hospital, Tours | Autism Spectrum Disorder, Bipolar Disorder | 05/21 | 05/21 | | |
NCT06296784: An E-health Psychoeducation for People With Bipolar Disorders |
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| Completed | N/A | 36 | Europe | e-health psychoeducation | University of Cagliari, Alessandra Perra | Bipolar Disorder, Psychoeducation, COVID-19 Pandemic | 11/21 | 11/21 | | |
NCT03379597: A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder |
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| Completed | N/A | 136 | RoW | Bifico (Live combined bifidobacterium,Lactobacillus and Enterococcus capsules, Oral), Dietary fiber | Central South University | Schizophrenia, Bipolar Disorder | 05/21 | 06/21 | | |
| Active, not recruiting | N/A | 60 | Europe | Emotional Stroop Task, Classic Stroop Task, Categorization of Emotional Stimuli Task | University Hospital, Grenoble | Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder | 06/21 | 10/22 | | |
NCT06369805: EVALUATION OF BLOOD BIOMARKER-BASED DIAGNOSTIC AID IN OUTPATIENTS SUFFERING FROM DEPRESSION |
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| Completed | N/A | 307 | Europe | there is no intervention | Les Toises - Psychiatry and Psychotherapy Center | Depressive Disorder, Bipolar Disorder, Bipolar Depression | 11/22 | 11/22 | | |
| Recruiting | N/A | 825 | | Nil | West China Hospital, Sichuan University; West China Hospital, Sichuan University, National plan project for key research and development (2018YFC1312300) | Schizophrenia, depression, bipolar disorder | | | | |
NCT06081634: Study Efficacy of Enhancing Cognitive Reserve in Patients With a First Bipolar Episode |
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| Completed | N/A | 120 | Europe | Enhancing cognitive reserve, Treatment as Usual | Hospital Clinic of Barcelona, FIDMAG Germanes Hospitalàries | Bipolar Disorder | 06/21 | 06/23 | | |
NCT03513549: Observational Study Evaluating the Safety of ADASUVE® in Agitation Associated With Schizophrenia or Bipolar I Disorder |
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| Recruiting | N/A | 10000 | US | Loxapine 10 MG, ADASUVE (loxapine) inhalation powder, NDA 022549 | Alexza Pharmaceuticals, Inc., Pharmaceutical Research Associates | Agitation,Psychomotor | 10/21 | 03/22 | | |
ChiCTR1900025993: The effect of functioning, clinical symptoms and related biomarkers in Chinese patients with bipolar disorder |
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| Not yet recruiting | N/A | 240 | | functional remediation ;treatment as usual | Tianjin Anding Hospital; Tianjin Anding Hospital, Supported by Henan Key Laboratory of Neurorestoratology (HNSJXF-2018-011) | bipolar disorder | | | | |
NCT01655030: Creatine Monohydrate as Adjuvant Therapy for Bipolar Depression |
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| Completed | N/A | 44 | RoW | creatine monohydrate, placebo | University of Sao Paulo | Bipolar I Disorder, Current Episode Depressed | 03/16 | 03/16 | | |
NCT06524505: Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression |
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| Recruiting | N/A | 100 | RoW | deep Transcranial Magnetic Stimulation (dTMS) -active, deep Transcranial Magnetic Stimulation (dTMS) -sham | Tianjin Anding Hospital | Bipolar Depression | 10/24 | 11/24 | | |
NCT05098353: Seroquel ® in Patients With Bipolar Disorder in Remission With Signs of Impaired Impulse Control |
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| Recruiting | N/A | 30 | RoW | Quetiapine, Quetiapine - impulsivity | Federal Stare Budgetary Scientific Institution, Mental Health Research Center, Kazan State Medical University, Federal State Budgetary Institution V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology, Saint-Petersburg, Russia | Bipolar Affective Disorder | 11/21 | 12/21 | | |
NCT04058249: Accelerated Theta Burst Stimulation for Inpatients With Bipolar Disorder |
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| Terminated | N/A | 1 | US | Accelerated intermittent theta-burst stimulation over right DLPFC | Stanford University | Bipolar Disorder, Manic, Bipolar Disorder I | 12/21 | 12/21 | | |
| Enrolling by invitation | N/A | 180 | Europe | Community mental health team, CMHT | The National Center for Public Health and Analyzes, Bulgaria, STICHTING TRIMBOS INSTITUT, NETHERLANDS | Bipolar Disorder, Schizophrenia, Severe Depression | 01/22 | 06/22 | | |
NCT06126198: rTMS Feasibility Study on Adolescent Depression Stimulation |
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| Enrolling by invitation | N/A | 20 | Europe | Repetitive Transcranial Magnetic Stimulation (rTMS) | Uppsala University, Uppsala University Hospital | Major Depressive Disorder, Unipolar Depression, Bipolar Depression | 12/23 | 12/23 | | |
NCT04427137: Accelerated LFR for Bipolar Patients During the COVID-19 Pandemic |
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| Completed | N/A | 29 | Canada | MagPro X100 Stimulator, B70 Fluid-Cooled Coil | Centre for Addiction and Mental Health | Bipolar Depression | 01/22 | 11/22 | | |
NCT05801562: Development of a Software Tool, Using Artificial Intelligence, That Integrates Clinical, Biological, Genetic and Imaging Data to Predict Diagnosis and Outcome of Depressed Patients in Order to Enhance Prognosis and Limiting Healthcare Costs. |
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| Recruiting | N/A | 730 | Europe | | IRCCS San Raffaele, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Bipolar Disorder, Unipolar Depression | 01/22 | 02/25 | | |
NCT05747612: Mental Coaching and Counseling for Bipolar Patients: Dealing With Moments of Crisis in Times of COVID-19. |
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| Completed | N/A | 50 | Europe | Counseling and Coaching | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | To Determine the Incidence of Depression in Subjects Affected by Bipolar Disorder | 01/22 | 02/23 | | |
Predibip, NCT04703972: Identification of Predictive Biomarkers of Mood Relapses in Patients With Bipolar Disorder |
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| Not yet recruiting | N/A | 10 | NA | clinical assessment (mood relapses identification), physiological data monitoring | University Hospital, Grenoble, Commissariat A L'energie Atomique | Bipolar Disorder | 01/22 | 06/22 | | |
NCT03722082: Enhancing Cognitive Reserve of the Offsprings of Bipolar and Schizophrenic Patients |
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| Recruiting | N/A | 173 | Europe | Enhancing Cognitive Reserve, Support intervention | Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Consorcio Centro de Investigación Biomédica en Red, M.P., Instituto de Salud Carlos III | Bipolar and Related Disorders | 02/22 | 06/22 | | |
| Recruiting | N/A | 90 | Europe | behavioral assessment | University Hospital, Grenoble | Bipolar Disorder | 02/22 | 02/22 | | |
ChiCTR1900021379: The efficacy, safety and related mechanisms of bifidobacteria in the adjuvant treatment of bipolar disorder |
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| Not yet recruiting | N/A | 120 | | Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules ;Placebo capsules | Second Xiangya Hospital, Central South University.; Second Xiangya Hospital, NSFC81501163 | Bipolar Disorder | | | | |
| Completed | N/A | 37 | Europe | Metacognitive and Defusion Training | Max-Planck-Institute of Psychiatry | Schizophrenia, Schizotypal Disorder, Delusional Disorder, Brief Psychotic Disorder, Shared Psychotic Disorder, Schizoaffective Disorder, Other Psychotic Disorder Not Due to A Substance or Known Physiological Condition, Unspecified Psychosis Not Due to a Substance or Known Physiological Condition, Manic Episode, Severe With Psychotic Symptoms, Bipolar Disorder, Current Episode Manic Severe With Psychotic Features, Bipolar Disorder, Current Episode Depressed, Severe, With Psychotic Features, Major Depressive Disorder, Single Episode, Severe With Psychotic Features, Major Depressive Disorder, Recurrent, Severe With Psychotic Symptoms | 03/22 | 09/23 | | |
R-Bipolar, NCT06176001: Group-based Psychoeducation for Relatives of Patients With Bipolar Disorder, a Randomized Controlled Trial |
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| Recruiting | N/A | 200 | Europe | psychoeducation in groups | Mental Health Services in the Capital Region, Denmark | Bipolar Disorder | 06/24 | 06/24 | | |
NCT02778256: Study of the Effectiveness of Vestibular Stimulation Treatment in the Depressive Phase of Bipolar Disorder |
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| Recruiting | N/A | 120 | RoW | Vestibular stimulation, Sham vestibular stimulation | Vest Brain,Centro de Estudios Neurovestibulares | Bipolar Disorder, Depression, Bipolar | 05/22 | 10/24 | | |
NCT05954598: Effect of Probiotic vs Placebo on Cognition Outcomes in Patients With Bipolar Disorder |
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| Recruiting | N/A | 100 | RoW | probiotic | First Affiliated Hospital of Zhejiang University | Bipolar Disorder | 05/22 | 12/24 | | |
NCT06182787: Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient |
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| Recruiting | N/A | 130 | RoW | | Sheba Medical Center | Severe Mental Disorder, Schizophrenia, Personality Disorders, Mood Disorders, Bipolar Disorder, Depressive Disorder, Anxiety Disorders, Psychotic Episode, Schizoaffective Disorder | 10/24 | 10/24 | | |
NCT03633357: Imaging 5HT7 Antagonist Effects in Bipolar Disorder |
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| Recruiting | N/A | 68 | Europe | JNJ-18038683, Placebo | King's College London | Bipolar Disorder | 06/22 | 06/22 | | |
| Enrolling by invitation | N/A | 24 | NA | Vestibular test | Vest Brain,Centro de Estudios Neurovestibulares | Bipolar Disorder, Depression, Bipolar | 07/24 | 10/24 | | |
NCT04564573: Antidepressant Treatments and Cognitive Function of Bipolar Patients |
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| Recruiting | N/A | 124 | RoW | | Tianjin Anding Hospital | Bipolar Disorder, Cognition | 07/22 | 10/22 | | |
| Completed | N/A | 80 | Europe | Ketamine | Medical University of Gdansk | Treatment Resistant Depression, Bipolar Depression, Ketamine, Major Depressive Disorder | 07/22 | 07/22 | | |
| Completed | N/A | 48 | Europe | medication review | Psychiatric Research Unit, Region Zealand, Denmark, Steno Diabetes Center Sjaelland, Region Zealand | Schizophrenia, Diabetes, Metabolic Syndrome, Severe Mental Disorder, Major Depressive Disorder, Bipolar Disorder, Psychosis, Psychotic Disorders | 10/23 | 10/23 | | |
IPSRT, NCT05420792: The Effect of Interpersonal Relationships and Social Rhythm Therapy Individuals With Bipolar Disorder |
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| Active, not recruiting | N/A | 34 | RoW | Peplau Interpersonal Relations based IPSRT will be applied to the intervention group | Ege University | Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder | 08/22 | 10/22 | | |
MetaCOGNITION, NCT04590300: Impact of Cognitive & Metacognitive Performance on Knowledge Learning When Conducting Therapeutic Education Programs |
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| Completed | N/A | 108 | Europe | QUESTIONNAIRES | Centre Hospitalier Charles Perrens, Bordeaux | Schizophrenia, Bipolar Disorder | 09/22 | 12/22 | | |
| Recruiting | N/A | 120 | Europe | Psychiatric interview, Clinical, diagnostic and functional evaluation, neuropsychological assessment, NECT PROGRAM | Hospital Center Alpes-Isère, Hôpital le Vinatier, University Hospital, Grenoble, Clinique du Dauphiné, CH Annecy Genevois, University Hospital, Clermont-Ferrand, Centre Hospitalier Esquirol, Centre Hospitalier Universitaire de Nice, CHS LE VALMONT, University Hospital, Caen, University Hospital, Geneva, University Hospital, Montpellier | Schizophrenia, Bipolar Disorder, Borderline Personality Disorder, Social Function, Self-stigma | 09/22 | 04/23 | | |
RHAPSODY, NCT04939818: Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders |
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| Completed | N/A | 172 | Europe | | Novoic Limited, King's College London | Alzheimer Disease, Mild Cognitive Impairment, Dementia With Lewy Bodies, Dementia, Vascular, Frontotemporal Dementia, Primary Progressive Aphasia, Parkinson Disease, Motor Neuron Disease, Major Depressive Disorder, Bipolar Disorder, Amyotrophic Lateral Sclerosis | 09/22 | 09/22 | | |
NCT05878808: Obsessions and Suicidality in Youth With Bipolar 1 Disorder |
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| Completed | N/A | 80 | RoW | Psychometric assessment | Cairo University | Obsessions, Suicide, Bipolar I Disorder, Obsessive-Compulsive Disorder | 09/22 | 01/23 | | |
NCT06131866: Acceptance and Commitment Therapy Based Psychoeducation, Meaning of Life and Coping Skills in Bipolar Disorder |
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| Completed | N/A | 60 | RoW | Psychoeducation based on Acceptance and Commitment Therapy | Kubra TOHUMCU | Bipolar Disorder, Coping Skills | 02/24 | 03/24 | | |
ChiCTR2000035832: Exploring the application value of biological rhythm-related indicators and intervention techniques in the early warning and early intervention of bipolar disorder: a prospective, randomized, single-blind, controlled trial |
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| Not yet recruiting | N/A | 500 | | Antidepressant medication ;Interpersonal and social rhythm therapy with antidepressants ;Antidepressant combined with lithium ;Follow up | Shanghai Mental Health Center; Shanghai Mental Health Center, hree year action plan for promoting clinical skills and clinical innovation in municipal hospitals | MDD with high risk and subthreshold of mania | | | | |
ChiCTR2100050628: Effect of different intervention modes and mechanism of brain-gut axis in overweight or obese patients with bipolar disorder at stable stage |
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| Recruiting | N/A | 120 | | Healthy lifestyle education and therapy ;Orlistat capsule 0.12bid and healthy lifestyle education were added. ;Stop the original medication, change to lurasidone and healthy lifestyle education treatment ;RTMS treatment was added twice a week and healthy lifestyle education. | The First Affiliated Hospital of Zhejiang University Medical College; The First Affiliated Hospital of Zhejiang University Medical College, Matching funds | Bipolar disorder | | | | |
NCT04091828: Assessment of Cognitive Functions in Bipolar Patients |
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| Not yet recruiting | N/A | 72 | NA | | Assiut University | Bipolar Disorder | 10/22 | 11/22 | | |
ChiCTR2100051243: Effects of physical intervention on inflammatory response and amino acid metabolism in patients with mental illness |
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| Recruiting | N/A | 200 | | no ;No ;no | Chang'an Hospital; Chang'an Hospital, Self-funded by the department | schizophrenia;bipolar disorder;depressive disorder | | | | |
NCT05053204: Influence Factors and Cognitive Characteristics in Unipolar and Bipolar Depression:Based on the THINC-it Tool |
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| Recruiting | N/A | 120 | RoW | | Shanghai Mental Health Center | Cognitive Impairments | 10/22 | 06/23 | | |
ChiCTR2000031360: A randomized controlled study on the effect of different light intensity for patients with bipolar depression |
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| Not yet recruiting | N/A | 120 | | light intensity 5000lx ;light intensity 10000lx | Pudong Nanhui Mental Health Center, Shanghai; Pudong Nanhui Mental Health Center, Shanghai, General project of Shanghai Pudong New Area Health Committee(PW2019A-30) | Bipolar Depression | | | | |
| Recruiting | N/A | 240 | RoW | Faecal genome | First Affiliated Hospital Xi'an Jiaotong University | Bipolar Disorder, Major Depressive Disorder | 11/22 | 11/22 | | |
NCT05249309: Naturalistic Study of Ketamine in the Treatment of Depression |
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| Active, not recruiting | N/A | 90 | RoW | Ketamine, Ketalar | Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul, Hospital Moinhos de Vento | Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder, Affective Disorder | 11/22 | 12/23 | | |