| Autoimmune Diseases |
NCT00862758: Request for Single Patient IND for Compassionate/Emergency Use of Tocilizumab |
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| No Longer Available | N/A | | US | Tocilizumab | University of Oklahoma, Hoffmann-La Roche | Juvenile Idiopathic Arthritis | 10/10 | 10/10 | | |
LBRA99, NCT00931086: Expanded Access Trial of Belimumab Antibody in RA Patients Who Were Previously Treated Under HGS Protocol |
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| No Longer Available | N/A | | US | belimumab, BENLYSTA™ (belimumab), LymphoStat-B™ | Human Genome Sciences Inc., a GSK Company, GlaxoSmithKline | Rheumatoid Arthritis | 12/11 | 12/11 | | |
NCT01373333: Use Of 3,4-Diaminopyridine (3,4-DAP) In The Treatment Of Lambert Eaton Myasthenic Syndrome |
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| No Longer Available | N/A | | US | 3,4 DAP | The Cleveland Clinic | Lambert-Eaton Myasthenic Syndrome | 09/12 | | | |
NCT02441920: Chronic Periodontitis and Tooth Loss in Patients With Rheumatoid Arthritis |
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| Terminated | N/A | 400 | NA | | University of Birmingham, Dudley Group NHS Foundation Trust | Periodontitis, Rheumatoid Arthritis | 11/12 | 11/12 | | |
NCT00948493: Treatment Use of Generex Oral-lyn™ in Patients With Diabetes |
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| No Longer Available | N/A | | US | Buccal insulin spray, Generex Oral-lynTM (oral, buccal insulin spray) | Generex Biotechnology Corp. | Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus | | | | |
NCT01049633: B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure |
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| No Longer Available | N/A | | US | Allogeneic Pancreatic Islet Cells, Sirolimus, Basiliximab, Tacrolimus, Antibacterial, Antifungal, and Antiviral Prophylaxis, Trimethoprim/sulfamethoxazole, Septra SS, Clotrimazole, Mycelex Troche, Valganciclovir, Valcyte, Heparin, Anticoagulation and Hematological Agent, Enoxaparin, Lovenox; Anticoagulation and Hematological Agent, Pentoxifylline, Aspirin, ASA | National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type 1 Diabetes Mellitus | | | | |
NCT01378546: Treatment of Lambert-Eaton Myasthenic Syndrome (LEMS) With 3, 4 DAP |
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| No Longer Available | N/A | | US | 3,4-diaminopyridine | Louis H. Weimer, MD | Lambert Eaton Myasthenic Syndrome (LEMS) | 05/15 | | | |
NCT02008188: Early Feasibility Study of Adaptive Advisory/Automated (AAA) Control of Type 1 Diabetes (Italy) |
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| Active, not recruiting | N/A | 12 | Europe | Closed Loop Control with the Advisory/Automated Adaptive (AAA) Control system | University of Virginia, National Institutes of Health (NIH) | Type 1 Diabetes Mellitus | 05/15 | 05/15 | | |
NCT02264405: Autologous SCT for Progressive Systemic Sclerosis: a Prospective NIS Study |
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| Recruiting | N/A | 50 | Europe | Autologous HSCT | European Group for Blood and Marrow Transplantation | Autoimmune Diseases | 12/15 | 12/17 | | |
NCT01309022: Immunosuppressive Medications for Participants in ITN005CT (NCT00014911) |
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| No Longer Available | N/A | | US | Sirolimus, Rapamune®, Tacrolimus, Prograf®, Mycophenolate mofetil, MMF, CellCept, Mycophenolic acid, Myfortic® | National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN) | Diabetes Mellitus, Type 1 | | | | |
| No Longer Available | N/A | | RoW | Technetium labelled glucosamine | University of Sydney, AbbVie | Rheumatoid Arthritis, Ankylosing Spondylitis | | | | |
NCT02149732: Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation |
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| Available | N/A | | RoW | cultivated oral mucosal epithelial sheet transplantation | Seoul National University Hospital, Ministry of Health & Welfare, Korea | Limbal Stem Cell Deficiency, Stevens-johnson Syndrome, Ocular Cicatricial Pemphigoid, Chemical Burn | 12/16 | 12/16 | | |
NCT02807285: Expanded Access Program for Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis |
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| No Longer Available | N/A | | US | Ocrelizumab, RO4964913 | Genentech, Inc. | Multiple Sclerosis | | | | |
NCT03125486: Compassionate Use for Subcutaneous (SC) Belimumab |
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| No Longer Available | N/A | | US | SC belimumab 200 mg | GlaxoSmithKline | Systemic Lupus Erythematosus | | | | |
NCT02722070: Processing Integration in Neurological Patients Using fMRI |
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| Not yet recruiting | N/A | 150 | RoW | 3 Tesla Siemens Skyra MRI scanner | Hadassah Medical Organization | Acute Inflammatory Demyelinating Polyradiculoneuropathy, Stroke, Anosognosia, Central and Peripheral Neurodegenerative Pathologies, Neuropsychiatric Conditions | 03/20 | 03/25 | | |
NCT02557295: An Observational Study to Evaluate Safety and Efficacy of Remsima™ in Patients With RA |
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| Terminated | N/A | 248 | NA | | Celltrion | Rheumatoid Arthritis | 03/20 | 03/20 | | |
NCT03006991: Study of Methotrexate Given to Juvenile Idiopathic Arthritis Patients Based on Pharmacogenomics and Pharmacometrics |
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| Recruiting | N/A | 100 | RoW | therapeutic drug monitoring | Guangzhou Women and Children's Medical Center | Juvenile Idiopathic Arthritis | 12/20 | 12/23 | | |
| Recruiting | N/A | 200 | Europe | MRI scan (adolescent spine protocol), MRI scan (whole body protocol) | University College London Hospitals | Arthritis, Juvenile Idiopathic, Enthesitis-Related Arthritis, Juvenile | 01/21 | 01/26 | | |
| Recruiting | N/A | 150 | Europe | | J.M.W. Hazes, Erasmus Medical Center, Dutch Arthritis Association | Rheumatoid Arthritis, Pregnancy | 06/21 | 05/25 | | |
NCT02210741: Next-generation Sequencing (NGS) of Peripheral Blood Immune Repertoire in Graves' Disease |
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| Not yet recruiting | N/A | 200 | RoW | | National Taiwan University Hospital | Graves Disease | 02/24 | 02/24 | | |
| Recruiting | N/A | 1500 | Europe | No intervention | Assistance Publique - Hôpitaux de Paris, Societe Francaise de Rhumatologie | RheumatoId Arthritis | 11/24 | 02/25 | | |
NCT01055093: Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients |
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| Recruiting | N/A | 2000 | Europe | | German Diabetes Center | Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2 | 09/25 | 09/35 | | |
NCT02889016: Neurobiologic, Immunologic, and Rheumatologic Markers in Youth With PANS |
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| Recruiting | N/A | 500 | US | | Stanford University | Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections, PANS, PANDAS | 03/28 | 03/28 | | |
NCT01088360: Safety Study of Abatacept to Treat Rheumatoid Arthritis (B) |
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| Active, not recruiting | N/A | 20000 | NA | | Bristol-Myers Squibb, National Data Bank for Rheumatic Diseases (NDB) | Rheumatoid Arthritis | 06/29 | 06/29 | | |
| Recruiting | N/A | 6000 | Europe | Observational registry | Central Hospital, Nancy, France, Institut National de la Santé Et de la Recherche Médicale, France, University of Lorraine | Multiple Sclerosis | 01/30 | 01/30 | | |
