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ChiCTR1900021359: Dynamic facial changes in patients with acromegaly before and after surgery: Prospective controlled study based on 3D Facial Analysis |
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| Not yet recruiting | N/A | 33 | | NA | Chinese Academy of Medical Sciences Peking Union Medical College Hospital; Chinese Academy of Medical Sciences Peking Union Medical College Hospital, self-funded | acromegaly | | | | |
NCT04520646: A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy |
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| Recruiting | N/A | 10 | RoW | Empagliflozin | Huashan Hospital | Acromegaly, Cardiomyopathies | 08/21 | 08/22 | | |
NCT04420000: Effects of Mindfulness Therapy in Patients With Acromegaly and Cushing |
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| Completed | N/A | 60 | Europe | Mindfulness, Control | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, A.O. Ospedale Papa Giovanni XXIII, Consorcio Centro de Investigación Biomédica en Red (CIBER) | Patient Satisfaction | 09/21 | 10/21 | | |
NCT04529356: The TMS Treatment for Postoperative Headache in GH Tumor |
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| Not yet recruiting | N/A | 200 | NA | Transcranial magnetic stimulation, Acetaminophen | Huashan Hospital | Headache, Pituitary Tumor, Acromegaly | 09/21 | 09/22 | | |
| Recruiting | N/A | 50 | RoW | | Seoul National University Hospital | Sleep Apnea | 12/21 | 12/21 | | |
NCT03042026: Developing a Simple Recognition System of Acromegaly |
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| Recruiting | N/A | 80 | RoW | | National Taiwan University Hospital | Acromegaly | 06/22 | 06/27 | | |
| Recruiting | N/A | 20 | Europe | | University of Aarhus | Acromegaly, Growth Hormone Treatment, Sleep Apnea, Cardiovascular Diseases, Bone Diseases | 12/22 | 12/22 | | |
| Not yet recruiting | N/A | 110 | Europe | Performed 3 diagnostic tests (2 OGTT tests with 75 g of Glucose and 1 placebo test with 375 mg of Aspartam, Performed 2 diagnostic tests (2 OGTT tests with 75g of Glucose) | Assistance Publique - Hôpitaux de Paris | Acromegaly | 12/22 | 12/22 | | |
| Completed | N/A | 102 | Europe | Lanreotide autogel, Somatostatin Receptor ligand | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Acromegaly | 01/24 | 07/24 | | |
NCT06344650: Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess. |
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| Recruiting | N/A | 100 | Europe | Blood sample, Radiological tests, Questionnaires | IRCCS San Raffaele, Fondazione Policlinico Universitario Campus Bio-Medico, Istituto Auxologico Italiano | Acromegaly | 10/24 | 04/26 | | |
| Active, not recruiting | N/A | 500 | Europe | Acrodat software | University of Aarhus | Acromegaly | 10/23 | 02/25 | | |
NCT03807076: Modulating the GIP System in Patients With Acromegaly Due to a Pituitary Tumor |
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| Completed | N/A | 25 | Europe | GIP-A, Placebo | University of Copenhagen, Rigshospitalet, Denmark, Aarhus University Hospital, Aalborg University Hospital, Odense University Hospital, Herlev and Gentofte Hospital | Acromegaly Due to Pituitary Adenoma | 06/23 | 11/23 | | |
| Completed | N/A | 62 | Europe | | University of Roma La Sapienza | Acromegaly | 12/24 | 12/24 | | |
NCT03043586: Treatment Patterns and Treatment Outcomes for Acromegaly |
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| Active, not recruiting | N/A | 520 | US | | Columbia University, Ipsen | Acromegaly | 07/25 | 07/25 | | |
ChiCTR2100051015: Prediction of difficult airways in patients with acromegaly by preoperative magnetic resonance imaging |
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| Recruiting | N/A | | | | Beijing Tiantan Hospital, Capital Medical University; Beijing Tiantan Hospital, Capital Medical University, none | acromegaly | | | | |
NCT05184231: Patient and Physician Survey on Satisfaction With Somatostatin Analogue (SSA) Injections in Acromegaly in China |
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| Withdrawn | N/A | 216 | NA | | Ipsen | Acromegaly | 10/23 | 10/23 | | |
NCT00001595: An Investigation of Pituitary Tumors and Related Hypothalmic Disorders |
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| Recruiting | N/A | 2000 | US | MRI, Tissue specimen collection | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Panhypopituitarism, Gigantism/Acromegaly, Prolactinoma, Cushing Disease | | | | |
RAPSODIA, NCT06597383: The RApid Switch From 1st Generation Somatostatin Analogues to PaSireOtiDe In Acromegaly |
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| Recruiting | N/A | 100 | Europe | | IRCCS San Raffaele, University of Turin, Italy, University of Padova, Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Acromegaly | 11/24 | 11/24 | | |
NCT00921609: Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly |
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| Active, not recruiting | N/A | 20 | US | Oral glucose tolerance test | Cedars-Sinai Medical Center | Acromegaly | 04/25 | 04/25 | | |
| Recruiting | N/A | 30 | Europe | Medical surgery therapy | Istituto Auxologico Italiano, Politecnico di Milano | Acromegaly | 12/25 | 12/25 | | |
BackSOM, NCT06253897: A Study to Understand Participant's Experiences in Gastro-enteropancreatic Neuroendocrine Tumors (GEP-NETs) and Acromegaly |
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| Completed | N/A | 20 | US | | Ipsen | Gastro-enteropancreatic Neuroendocrine Tumor, Acromegaly | 12/24 | 12/24 | | |
ChiCTR2300072503: Assessment of cardiac structure and function by cardiac magnetic resonance imaging in acromegaly |
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| Recruiting | N/A | 60 | | no | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Discipline Excellence Development 1·3·5 Project of West China Hospital of Sichuan University (No: 2020HXFH034) | acromegaly | | | | |
NCT06326853: Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models |
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| Not yet recruiting | N/A | 200 | NA | | IRCCS San Raffaele | Endocrine Disorders, Adiposity, Pituitary Adenoma, Cushing Syndrome, Acromegaly, Hypopituitarism | 07/24 | 12/26 | | |
ChiCTR2300070856: Clinical study of speckle tracking imaging in early damage and prognosis assessment of acromegaly cardiomyopathy |
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| Recruiting | N/A | | | | 183 Xinqiao Zhengjie, Shapingba District, Chongqing; Xinqiao Hospital，Army Medical University, Chongqing Municipal Health Commission | Acromegaly cardiomyopathy | | | | |
NCT05431803: Real-World Study (RWS) of Lanreotide Autogel (LAN) for the Treatment of Patients With Acromegaly in China |
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| Completed | N/A | 129 | RoW | | Ipsen | Acromegaly | 12/24 | 12/24 | | |
| Recruiting | N/A | 1600 | RoW | Dynamic hormone study and Magnetic resonance imaging | Seoul National University Hospital | Pituitary Disease, Pituitary Incidentaloma, Acromegaly, Central Diabetes Insipidus, Pituitary Stalk Compression Hyperprolactinaemia, Cushing's Disease, Pituitary Tumor, Prolactinoma | 02/25 | 02/25 | | |
| Completed | N/A | 34 | Europe | HR-pQCT, High Resolution peripheral Quantitative Computed Tomography, DXA scan, Dual X-ray Absorptiometry, Bone microindentation, OsteoProbe, Hand grip and leg extension strength, Timed up-and-go test, Stabilometry, Balance board, Nerve conduction test, Visual acuity test | Christian Alexander H Rosendal, Ipsen, Pfizer | Acromegaly | 05/24 | 05/24 | | |
| Recruiting | N/A | 9 | US | Diet | Cedars-Sinai Medical Center | Acromegaly | 03/25 | 03/25 | | |
ChiCTR2400090129: To establish an evaluation model of acromegaly disease activity based on doctor-patient co-reporting, and to explore a new model of precision diagnosis and treatment and whole-process management |
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| Recruiting | N/A | 300 | | NA; NA; NA | Peking Union Medical College Hospital; Peking Union Medical College Hospital, Clinical Research Special Project of the Central High-level Hospital of Peking Union Medical College Hospital 2022-PUMCH-A-155 | Acromegaly | | | | |
| Not yet recruiting | N/A | 371 | | no | The First Affiliated Hospital of Army Medical University; The First Affiliated Hospital of Army Medical University, Subject of your choice | Pituitary adenoma, acromegaly, prolactinemia, ACTH adenoma, TSH adenoma | | | | |
NCT01809808: A Prospective Study of Outcome After Therapy for Acromegaly |
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| Active, not recruiting | N/A | 250 | US | Surgery for acromegaly, Medications for acromegaly, Drugs used to lower growth hormone, Total body magnetic resonance imaging, Adipose Tissue Biopsy | Columbia University, Icahn School of Medicine at Mount Sinai, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Acromegaly | 06/25 | 06/25 | | |
| Not yet recruiting | N/A | 12 | Europe | Usual clinical practice + hypoproteic diet | Azienda Ospedaliero Universitaria Maggiore della Carita | Acromegaly | 12/25 | 03/26 | | |
NCT05131100: Korean Regulatory Post Marketing Surveillance for Somavert |
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| Recruiting | N/A | 100 | RoW | Somavert | Pfizer | Acromegaly | 09/26 | 09/26 | | |
NCT03158090: The Longitudinal Approach to Acromegaly: A Pattern of Treatment and Comparative Effectiveness Research |
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| Recruiting | N/A | 1965 | RoW | Transnasal butterfly surgery, sandostatin, Lanreotide, radiotherapy | Ginkgo Leaf Center for Rare Disorders | Acromegaly | 12/50 | 01/51 | | |
| Recruiting | N/A | 1965 | | Surgery such as Transnasal butterfly surgery ;Drug treatment includes somatostatin analogues (SSA), dopamine receptor agonists and GH receptor antagonists ;Conventional radiotherapy methods include radiotherapy, linear accelerator X knife, gamma knife | Huiwen Tan, Zhiyong Chen; 1 Affiliated Hospital of Jinan University, Personal donation, Public donation, Fund application | Acromegaly | | | | |
ChiCTR2100049382: A single-center, retrospective+prospective, observational study to understand the clinical profile and cost-effectiveness of acromegaly in a real-world clinical setting |
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| Not yet recruiting | N/A | 300 | | None ;None ;None | The First Affiliated Hospital of Ji'nan University; The First Affiliated Hospital of Ji'nan University, self-raised | Acromegaly | | | | |
NCT00461188: Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA |
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| Recruiting | N/A | 10000 | Europe | | Barts & The London NHS Trust | Acromegaly, Gigantism, Familial Isolated Pituitary Adenoma, FIPA, Pituitary Adenoma Predisposition, PAP | 04/99 | 04/99 | | |
