| Linzess (linaclotide) / Ironwood Pharma, AbbVie |
NCT01279915: A Safety and Pharmacokinetics Study of ASP0456 in Healthy Subjects |
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| Completed | 1 | 32 | Japan | ASP0456, linaclotide, Placebo | Astellas Pharma Inc | Healthy, Pharmacokinetics of ASP0456 | 01/11 | 01/11 | | |
NCT01427387: A Study to Evaluate Safety of Multiple Dose of ASP0456 in Healthy Subjects |
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| Completed | 1 | 44 | Japan | ASP0456, linaclotide, Placebo | Astellas Pharma Inc | Healthy, Pharmacokinetics of ASP0456 | 09/11 | 09/11 | | |
NCT01912079: Trial of Linaclotide to Demonstrate Colorectal Bioactivity in Health Volunteers |
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| Not yet recruiting | 1 | 18 | US | linaclotide, Linzess, Placebo, PLCB | Fox Chase Cancer Center, National Cancer Institute (NCI) | Gastrointestinal Diseases, Gastrointestinal Neoplasms, Digestive System Diseases, Digestive System Abnormalities, Digestive System Neoplasms, Colorectal Neoplasms | 01/14 | | | |
NCT01950403: Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers |
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| Completed | 1 | 24 | US | linaclotide acetate, Linzess, MD-1100 Acetate, MM-416775, placebo, PLCB, pharmacological study, pharmacological studies, laboratory biomarker analysis | Mayo Clinic, National Cancer Institute (NCI) | Colorectal Cancer, Healthy, no Evidence of Disease | 04/16 | 02/18 | | |
LIN-PK-01, NCT02220348: A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically |
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| Completed | 1 | 7 | US | linaclotide, Linzess | Forest Laboratories | Breast Feeding, Constipation, Irritable Bowel Syndrome | 05/19 | 05/19 | | |
ChiCTR2400088166: A study on the application value of Linalotide capsules in colonoscopy bowel preparation |
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| Completed | 1 | 600 | | 3L of polyethylene glycol +linaclotide; 3L of polyethylene glycol; 2L of polyethylene glycol + linaclotide | Affiliated Hospital of Qingdao University; Affiliated Hospital of Qingdao University, None | none | | | | |
| Active, not recruiting | 1 | 43 | US | Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Esophagogastroduodenoscopy, EGD, Linaclotide, [9-L-tyrosine]heat-stable enterotoxin (Escherichia coli)-(6-19)-peptide, Linzess, MD-1100, Plecanatide, Trulance | University of Wisconsin, Madison, National Cancer Institute (NCI) | Barrett Esophagus, Gastroesophageal Reflux Disease, Malignant Digestive System Neoplasm | 02/26 | 02/26 | | |
