Zyclara (imiquimod) / Mochida, Viatris, Bausch Health 
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Zyclara (imiquimod) / Mochida, Viatris, Bausch Health
NCT06356012: Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated With Imiquimod

Not yet recruiting
4
96
NA
Imiquimod, IXIUM, Loop Electrosurgical Excision Procedure, LEEP
Barretos Cancer Hospital, Fundação de Amparo à Pesquisa do Estado de São Paulo, Farmoquimica S.A., Hospital de Cancer de Barretos - Fundacao Pio XII
HSIL, High-Grade Squamous Intraepithelial Lesions, Vaginal Microbiome, Biomarkers
12/26
12/28
2016-000712-15: Clinical study to compare two creams with the active substance imiquimod and one cream without active substance for patients with actinic keratosis

Ongoing
3
426
Europe
Imiquimod 5% cream, Aldara 5% Creme, Cream, Aldara 5% Creme
Dermapharm AG, Dermapharm AG
Actinic keratosis, Actinic keratosis, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
ANCHOR, NCT02135419: Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions

Active, not recruiting
3
4446
US
imiquimod, Aldara, IMQ, R 837, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, Efudex, infrared photocoagulation therapy, infrared coagulation, IRC, thermal ablation therapy, laser therapy, therapy, laser, clinical observation, observation, laboratory biomarker analysis
AIDS Malignancy Consortium, National Cancer Institute (NCI), The Emmes Company, LLC, University of Arkansas, University of California, San Francisco, University of Arizona
Anal Cancer, High-grade Squamous Intraepithelial Lesion, HIV Infection, Human Papilloma Virus Infection
08/21
03/24
NCT02059499: Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

Completed
3
91
US
imiquimod, Aldara, IMQ, R 837, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, questionnaire administration, laboratory biomarker analysis
AIDS Malignancy Consortium, National Cancer Institute (NCI), The Emmes Company, LLC, University of Arkansas
Anal Intraepithelial Neoplasia, High-grade Squamous Intraepithelial Lesion, HIV Infection
12/23
04/24
PRIOH-1, NCT03073967 / 2020-004940-27: Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects

Recruiting
3
153
Europe, Canada, US, RoW
Pritelivir, Investigator's choice, Foscarnet or Cidofovir or Imiquimod
AiCuris Anti-infective Cures AG, Medpace, Inc.
HSV Infection
01/25
04/25
2019-002285-12: Keramod Gel vs Aldara for the treatment of actinic keratosis Keramod Gel vs Aldara en el tratamiento de la queratosis actínica

Not yet recruiting
2
68
Europe
KERAMOD, NA, Gel, Cream, ALDARA
LABORATORIO OJER PHARMA, S.L., LABORATORIO OJER PHARMA, S.L.
ACTINIC QUERATOSIS, also known as solar keratosis, is a skin disease caused by chronic exposure to sunlight. It appears as scaly lesions on the skin as a result of an abnormal growth of the cells in the most outer layer of the epidermis. There may be a single lesion or multiple lesions, and they are usually found on areas of the skin that are regularly exposed to the sun, such as the face, neck, hands, forearms and scalp. QUERATOSIS ACTÍNICA, Conocida también como queratosis solar, La queratosis actínica es un parche grueso y escamoso en la piel, que se desarrolla después de muchos años de exposición al sol. Comúnmente se encuentra en el rostro, cuello, el dorso de las manos, los antebrazos y el cuero cabelludo., ACTINIC QUERATOSIS, also known as solar keratosis, is a skin disease caused by chronic exposure to sunlight. QUERATOSIS ACTÍNICA, Conocida también como queratosis solar, La queratosis actínica es un parche grueso y escamoso en la piel, que se desarrolla después de muchos años de exposición al sol., Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
2019-003567-21: Anti-inflammatory drugs in a TRL4 and TLR7 topical challenge model

Not yet recruiting
2
60
Europe
Aldara, Prednisolone solution 0.5 mg/kg, Ointment, Oral solution, Aldara 5%
Centre for Human Drug Research, Centre for Human Drug Research
None, None, Body processes [G] - Immune system processes [G12]
 
 
2021-005996-37: Gene and protein expression after treatment of actinic keratosis Gen- og proteinudtryk efter behandling af aktiniske keratoser.

Ongoing
2
60
Europe
Melatonin, Cream, Tolak, Aldara
Zealand University Hospital, Zealand University Hospital, RepoCeuticals A/S
Actinic keratoses, Solar keratoses, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
NCT06305910: CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Recruiting
1
24
US
Treatment with CD200AR-L, Imiquimod, GBM6-AD, Single dose of radiation (300 cGy)
OX2 Therapeutics
Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent High Grade Glioma
09/25
01/27
NCT03872947: A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Recruiting
1
187
Europe, US
TRK-950, Irinotecan, Leucovorin, 5-FU, Gemcitabine, Cisplatin, Carboplatin, Ramucirumab, Paclitaxel, Nivolumab, Pembrolizumab, Imiquimod Cream, Bevacizumab, PLD
Toray Industries, Inc
Solid Tumor, Colorectal Cancer, Cholangiocarcinoma, Bladder Cancer, Ovarian Cancer, Gastric Cancer, Palpable Subcutaneous Malignant Lesions, Renal Cell Carcinoma, Melanoma, Epithelial Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer
03/25
03/25
INTERCEPT-H3, NCT04808245: A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas

Recruiting
1
15
Europe
Tecentriq 1200 MG in 20 ML Injection, Atezolizumab, H3K27M peptide vaccine, Imiquimod (5%), Aldara
German Cancer Research Center, Johannes Gutenberg University Mainz, Charite University, Berlin, Germany, Roche Pharma AG, German Cancer Aid
Newly Diagnosed H3-mutated Glioma
03/25
03/25

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