cyclosporine / Generic mfg. 
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129 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
cyclosporine / Generic mfg.
ChiCTR1900023476: Multicenter, prospective and open clinical study for rapamycin in the treatment of autoimmune hemolytic anemia

Not yet recruiting
N/A
80
 
glucocorticoid ;glucocorticoid & Ciclosporin ;glucocorticoid & rapamycin ;rapamycin
Tianjin Medical University General Hospital; Tianjin Medical University General Hospital, Clinical Founding
Autoimmune
 
 
ChiCTR1800015455: Lidocaine intravenous infusion versus cyclosporine in treatment of severe atopic dermatitis aged 12-70: a multicentered, randomized, paralleled trial

Not yet recruiting
N/A
120
 
lidocaine intravenous infusion ;oral cyclosporine
Shanghai Jiaotong University School of Medecin, Xinhua hospital; Shanghai Jiaotong University School of Medecin, Xinhua hospital, Shanghai Jiaotong University School of Medecin
Atopic dermatitis
 
 
ChiCTR1800019308: Efficacy and tolerability of multitarget therapy with NHMX for systemic lupus erythematosus

Recruiting
N/A
150
 
One kind of non-steroid anti-inflammatory drugs combines with hydroxychloroquine sulfate(≤200mg/bid) and methotrexate(7.5-20mg/w), with addition of glucocorticoid (≤0.5mg/kg·d) or cyclosporine (maintaining the drug concentration between 30-90ug/l) ;hydroxychloroquine sulfate(≤200mg/bid) and methotrexate(7.5-20mg/w), with addition of glucocorticoid (≤0.5mg/kg·d) or cyclosporine(maintaining the drug concentration between 30-90ug/l)
The Third Affiliated Hospital, Southern Medical University; The Third Affiliated Hospital, Southern Medical University, Guangdong Project of Science and Technology
systemic lupus erythematosus
 
 
ChiCTR-IOR-16008738: A single center, randomized, controlled, opened label study for evaluating Cyclosporin alone or combined with Stanozolol in the treatment of aplastic anemia

Recruiting
N/A
200
 
Cyclosporin ;Cyclosporin and Stanozolol
The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, The First Affiliated Hospital of Zhengzhou University Dr.Scientific Research Foundation
aplastic anemia
 
 
ChiCTR1900024692: Comparison of the efficacy of azathioprine and cyclosporine in myasthenia gravis immune modification

Recruiting
N/A
100
 
bromopyramine + hormone ;bromopyramine + hormone + azathioprine ;bromopyramine + hormone + cyclosporine ;bromopyramine + hormone + azathioprine ;bromopyramine + hormone + cyclosporine
Neurology Department of the 940th Hospital of Joint Logistics Support force of Chinese People's Liberation Army; The 940th Hospital of the People's Liberation Army Joint Service Support Force, The National Natural Science Foundation of China (81200247) and the Natural Science Foundation of Gansu Province (1606RJZA190; 1506RJZA302)
Myasthenia Gravis
 
 
ChiCTR1800019487: A clinical study for different infusion methods of mesenchymal stem cells in the treatment of aplastic anemia

Recruiting
N/A
60
 
Treatment regimen of ATG combined with cyclosporin immunosuppression ;MSCs+Treatment regimen of ATG combined with cyclosporin immunosuppression
Jiangmen Central Hospital; Jiangmen Central Hospital, Wu Jieping medical association foundation
Aplastic anemia
 
 
ChiCTR2000038744: To explore the intervention effect of Xiaoyu Xiezhuo Yin on chronic cyclosporin nephropathy in patients with aplastic anemia based on autophagy and ACE2-Ang(1-7)-Mas axis

Not yet recruiting
N/A
60
 
none ;none ;Conventional treatment ;Conventional treatment+traditional Chinese medicine
The First Affiliated Hospital of ZheJiang Chinese Medical University; The First Affiliated Hospital of ZheJiang Chinese Medical University, Self-funded
Chronic cyclosporine nephropathy
 
 
ChiCTR1900027553: Clinical therapies for patients in subtypes of non-severe aplastic anemia

Not yet recruiting
N/A
490
 
Cyclosporine ;Cyclosporine ;Cyclosporine+Danazol ;CSA+TPO+G-CSF
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences; Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences, Tianjin Major Disease Prevention and Control Science and Technology Project
non-severe aplastic anemia
 
 
ChiCTR2000029262: Clinical study on the relationship between SLC35 gene variation and psoriasis

Not yet recruiting
N/A
360
 
Acitretin Capsule ;Methotrexate Tablets ;ciclosporin soft capsules
Dermatology Hospital of Southern Medical University; Dermatology Hospital of Southern Medical University, Horizontal project start-up funding
psoriasis
 
 
ChiCTR2000036709: Study on early warning of rapid progressive interstitial lung disease in dermatomyositis

Not yet recruiting
N/A
30
 
Glucocorticoid + cyclophosphamide + cyclosporin ;Glucocorticoid + cyclophosphamide + Tofacitinib
Zhongshan Hospital of Fudan University; Zhongshan Hospital of Fudan University, Shanghai Shenkang Hospital development Center
Dermatomyositis
 
 
ChiCTR2100053501: Dexamethasone, rituximab plus cyclosporine in the treatment of adults with primary immune thrombocytopenia

Recruiting
N/A
30
 
Combination therapy
The 967th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army ; The 967th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, self-financed
primary immune thrombocytopenia (ITP)
 
 
ChiCTR2000036690: Clinical study on precise clinical classification and treatment strategy verification of adult onset still's disease

Not yet recruiting
N/A
80
 
MTX; Cyclosporin
Department of Rheumatology and Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shengkang Shanghai
adult onset still's disease
 
 
ChiCTR2000029921: Sirolimus combined with calcineurin inhibitors for steroid-ineffective/dependent cGVHD: multicenter, single-arm study

Not yet recruiting
N/A
78
 
given sirolimus capsules combined with ciclosporin(CsA) or tacrolimus(FK506) capsules
The Hematology Department of Xinqiao Hospital, the Second Affiliated Hospital of The Army Medical University; Level of the institution:, Army medical university clinical innovation training program
Steroid- ineffective/dependent cGVHD
 
 
ChiCTR2200058433: Belimumab in combination with cyclosporine for corticosteroid-refractory primary immune thrombocytopenia in adults

Not yet recruiting
N/A
37
 
belimumab and cyclosporine
The Second Affiliated Hospital of Kunming Medical University; The Second Affiliated Hospital of Kunming Medical University, Self-financing
Primary immune thrombocytopenia
 
 
NCT05782933: Efficacy of Rituximab Combined With Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy

Recruiting
N/A
2
RoW
Rituximab, Modified Ponticelli regimen
Beijing Friendship Hospital
Idiopathic Membranous Nephropathy
12/23
12/23
NCT05571332: Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function

Recruiting
N/A
39
RoW
Avatrombopag 20 MG Oral Tablet, porcine ATG, Cyclosporine(CsA)
Institute of Hematology & Blood Diseases Hospital
Aplastic Anemia
12/23
06/24
ChiCTR2200065012: A Prospective Randomized Controlled Clinical Study on the Intervention of Primary Membranous Nephropathy by Strengthening the Spleen, Benefiting the Kidney and Dispelling the Wind

Recruiting
N/A
228
 
Use the following regimens in addition to basic treatment: 0-24 weeks (trial): the subjects take Moshen granule, one bag Bid, after meals. 24-48 weeks (follow-up) :Continue to use a scale of 0-24 weeks Experimental group. ;Use the following regimens in addition to basic treatment: 0-24 weeks (trial): the subjects take Moshen granule simulant, once in the morning and evening, one bag at a time, after meals. 24-48 weeks (follow-up) :Continue to use a scale of 0-24 weeks. ;Membranous kidney Membranous kidney granules, 1 bag Bid, after meals. Cyclosporine was also taken orally in two equal doses with an interval of 12 hours. Week 24-48 (follow-up) : The 0-24 week regimen was continued. ;Moshen granule simulant 1 bag Bid, after meals. Cyclosporine was also taken orally in two equal doses with an interval of 12 hours. Week 24-48 (follow-up) : The 0-24 week regimen was continued.
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Science and Technology Ministry,National key research and development program-Special Research Project on Modernization of traditional Chinese Medicine
Primary membranous nephropathy
 
 
NCT02845596: Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Active, not recruiting
N/A
40
US
cyclosporine, Matched Unrelated Donor Hematopoietic Stem Cell Transplant, horse anti-thymocyte globulin (ATG), ATGAM, rabbit anti-thymocyte globulin (ATG), Thymoglobulin, methotrexate, fludarabine, cyclophosphamide, low-dose total body irradiation (TBI), Immunosuppressive Therapy (IST)
Michael Pulsipher, MD
Severe Aplastic Anemia
04/24
04/24
ChiCTR2000031716: Study of cyclosporine in improving the prognosis of recurrent pregnancy with unexplained recurrent spontaneous abortion

Not yet recruiting
N/A
572
 
Cyclosporine ;Dydrogesterone
Obstetrics & Gynecology Hospital of Fudan University; Obstetrics & Gynecology Hospital of Fudan University, Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
unexplained recurrent spontaneous abortion
 
 
ChiCTR2200059843: Computer simulation model based on physiologically based pharmacokinetic to guide the individualized drug administration strategy of posaconazole in pediatric

Not yet recruiting
N/A
278
 
Before the 7th day of medication, blood samples were collected for the determination of posaconazole concentration ;Before the 7th day of medication, blood samples were collected for the determination of posaconazole and cyclosporine concentrations ;PBPK model prediction were used to guide the individual prescription of Posaconazole ;Before the 7th day of medication, blood samples were collected for the determination of posaconazole concentration ;PBPK model prediction were used to guide the individual prescription of Posaconazole and cyclosporine ;Before the 7th day of medication, blood samples were collected for the determination of posaconazole and cyclosporine concentrations
Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University; Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai Health Commission Clinical Research Fund
Prevention or treatment of invasive fungal disease
 
 
ScanCLAD, NCT02936505 / 2015-004137-27: Clinical Study Evaluating Two Treatment Protocols for Immunosuppressive Drugs. Looking at 3-year Incidence of CLAD.

Active, not recruiting
N/A
249
Europe
Cyclosporine, Sandimmun Neural, Mycophenolate mofetil (MMF), Cellcept, Rabbit Anti thymocyte globulin, Thymoglobulin®, Corticosteroids, Methylprednisolon, Tacrolimus, Advagraf®
Vastra Gotaland Region, Oslo University Hospital, Helsinki University Central Hospital, Skane University Hospital, Copenhagen University Hospital, Denmark
Lung Transplantation, Allografts
10/25
10/26
TOCASU, NCT05112263: Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative Colitis

Not yet recruiting
N/A
96
NA
Tofacitinib, Cyclosporine
Postgraduate Institute of Medical Education and Research, All India Institute of Medical Sciences, New Delhi
Ulcerative Colitis
12/25
06/26
ChiCTR2300070171: Clinical Multicenter Study of Tocilizumab in the Treatment of sJIA-MAS

Not yet recruiting
N/A
90
 
Cyclosporin ;Tocilizumab (Use on the fourth day) ;Tocilizumab (For use on the eighth day)
Children's Hospital, Zhejiang University School of Medicine; Children's Hospital, Zhejiang University School of Medicine, Zhejiang Lingyan Project
Juvenile idiopathic arthritis complicated with macrophage activation syndrome
 
 
NCT05936086: A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLH

Recruiting
N/A
160
RoW
Cytoxan, Etoposide, VP16, Dexamethasone, Cyclosporine (CSA)
shifeng Lou
Hemophagocytic Syndrome
04/26
05/27
ACTRN12618001084279: Cyclosporin for moderate to severe alopecia areata and tofacitinib extension

Recruiting
N/A
38
 
Sinclair Dermatology, Australia Alopecia Areata Foundation
Alopecia areata
 
 
NCT05588869: Cyclosporine Adverse Outcomes in Steroid Dependent and Frequent Relapsing Nephrotic Syndrome in Children;Single Center Study

Not yet recruiting
N/A
30
RoW
observation of the adverse outcomes of Cyclosporine in steroid dependent and frequent relapsing nephrotic syndrome in children
Sohag University
Steroid Dependent and Frequent Relapsing Nephrotic Syndrome
04/23
04/23
NCT05120687: Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH

Recruiting
N/A
200
RoW
noncorticosteroid systemic immunomodulatory therapy (NCSIT), Methotrexate, Adalimumab, cyclophosphamide, Cyclosporin, Mycophenolate Mofetil
Sun Yat-sen University
Vogt Koyanagi Harada Disease (VKH)
10/24
10/25
pSS, NCT05605314: Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye

Recruiting
N/A
500
RoW
Cyclosporine
Peking University Third Hospital
Dry Eye
01/27
01/28
BIOBADATOP, NCT05674695: Spanish Academy of Dermatology and Venereology Registry of Atopic Dermatitis Therapy

Recruiting
N/A
2500
Europe
Ciclosporin, Methotrexate, Dupilumab, Corticosteroids, Omalizumab, Baricitinib, Upadacitinib, Tralokimumab, Topical corticosteroids
Fundación Academia Española de Dermatología
Dermatitis, Atopic
01/29
01/29
 

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