Leukemia  >>  cyclosporine 
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15 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
cyclosporine / Generic mfg.
jRCTs031180243: JCOG0907: A Non-Randomized Validation Trial of a Therapy Incorporating Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Adult T-Cell Leukemia and Lymphoma

Completed
3
110
Japan
carboplatin - Generic mfg., cytarabine - Generic mfg., methotrexate - Generic mfg., prednisolone - Generic mfg., vincristine - Generic mfg., cyclophosphamide - Generic mfg., doxorubicin hydrochloride - Generic mfg., Cymerin (ranimustine) - Mitsubishi Tanabe, vindesine - Generic mfg., etoposide oral - Generic mfg., busulfan - Generic mfg., cyclosporine - Generic mfg., tacrolimus oral - Generic mfg., fludarabine oral - Generic mfg., prednisolone - Generic mfg., Lioplim (filgrastim) - Abbott, Neu-up (nartograstim) - Yakult Honsha, Granocyte (lenograstim) - Roche, Poteligeo (mogamulizumab-kpkc) - Kyowa Kirin
Saitama Medical University International Medical Center
Adult T-cell leukemia-lymphoma
 
 
BIG-1, NCT02416388: Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR

Recruiting
2/3
3100
Europe
Idarubicin, Daunorubicin, HD Cytarabine, Cyclosporine, Methotrexate, Mycophenolic acid (MPA), vosaroxin, ID cytarabine, Dexamethasone, Venetoclax
University Hospital, Angers
Acute Myeloid Leukemia (AML)
06/24
 
ACTRN12605000380695: Induction Of Mixed Haematopoietic Chimerism In Patients Using Fludarabine, Low Dose Total Body Irradiation, Peripheral Blood Stem Cell Infusion And Post-Transplant Immunosuppression With Cyclosporine And Mycophenolate Mofetil

Active, not recruiting
2
40
 
A/Prof Durrant
Myelodysplastic syndromes., Myeloproliferative syndromes., Acute Leukemia with < 10% blasts., Amyloidosis, Hodgkins disease., Multiple Myeloma, Non-Hodgkins lymphoma, Chronic myeloid leukaemia, Chronic lymphocytic leukaemia, Renal cell carcinoma
 
 
NCT00544115: Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Active, not recruiting
2
260
NA
busulfan, cyclophosphamide, cyclosporine, etoposide, fludarabine phosphate, melphalan, methotrexate, mycophenolate mofetil, sirolimus, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
City of Hope Medical Center, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Precancerous/Nonmalignant Condition
03/07
12/24
NCT00388102: Cyclophosphamide, Fludarabine, Total-Body Irradiation, and Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer or Other Disease

Recruiting
2
30
US
filgrastim, cyclophosphamide, cyclosporine, fludarabine phosphate, mycophenolate mofetil, cytogenetic analysis, flow cytometry, laboratory biomarker analysis, umbilical cord blood transplantation, total-body irradiation
Memorial Sloan-Kettering Cancer Center
Leukemia, Lymphoma, Myelodysplastic Syndromes
03/10
 
NCT00534430: Busulfan, Etoposide, and Total-Body Irradiation in Treating Patients Undergoing Donor Stem Cell or Bone Marrow Transplant for Advanced Hematologic Cancer

Active, not recruiting
2
30
NA
busulfan, cyclosporine, etoposide, mycophenolate mofetil, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
City of Hope Medical Center, National Cancer Institute (NCI)
Leukemia, Myelodysplastic Syndromes
04/10
12/24
NCT00398346: Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

Recruiting
2
68
US
therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, fludarabine phosphate, tacrolimus, allogeneic hematopoietic stem cell transplantation, in vitro-treated peripheral blood stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
National Heart, Lung, and Blood Institute (NHLBI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Secondary Myelofibrosis, Small Intestine Cancer
12/10
 
NCT00066300: Allogeneic Peripheral Stem Cell Transplantation Followed By Donor Lymphocyte Infusions in Treating Patients With Hematologic Cancer

Active, not recruiting
2
US
graft-versus-tumor induction therapy, therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, fludarabine phosphate, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation, radiation therapy
National Heart, Lung, and Blood Institute (NHLBI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
 
 
2013-000238-37: Treatment guided by detection of Minimal Residual Disease after allogeneic stem cell transplantation in Acute Myeloid Leukaemia

Ongoing
2
31
Europe
ciclosporin, mofetil mycophenolate, L04AD01, L04AA06,
VU University medical center, VU University medical center
Minimal residual disease after allogeneic stem cell transplantation in Acute Myeloid Leukaemia
 
 
NCT03434730: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation

Active, not recruiting
2
46
US
Total Body Irradiation, TBI, Cyclosporine, Sandimmune, Mycophenolate Mofetil, CellCept, Tocilizumab, Acemtra, Filgrastim, Granulocyte-Colony Stimulating Factor, Neupogen
Memorial Sloan Kettering Cancer Center
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Myelodysplastic-Myeloproliferative Diseases, Myeloproliferative Disorder, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Leukemia
02/25
02/25
NCT00357565: Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia

Active, not recruiting
2
33
US
filgrastim, G-CSF, busulfan, Busulfex, cyclosporine, CSA, fludarabine phosphate, Fludara, melphalan, Alkeran, mycophenolate mofetil, MMF, umbilical cord blood transplantation
Masonic Cancer Center, University of Minnesota
Leukemia, Myelodysplastic Syndromes, Childhood Acute Myeloid Leukemia in Remission, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Previously Treated Myelodysplastic Syndrome, Secondary Myelodysplastic Syndrome, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Excess Blasts, Refractory Anemia, De Novo Myelodysplastic Syndrome, Childhood Myelodysplastic Syndrome
06/24
12/25
MoTD, NCT04888741 / 2019-002419-24: Methods of T Cell Depletion Trial

Recruiting
2
400
Europe
Thymoglobulin, ATG, Cyclophosphamide, Cyclosporine, Sirolimus, Mycophenolate Mofetil, MMF
University of Birmingham, IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia, Myelofibrosis
01/26
01/26
NCT03842696: Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Recruiting
1/2
49
US
Vorinostat, Blood and Marrow Transplant (BMT), Tacrolimus (or cyclosporine), Methotrexate, Mycophenolate Mofetil (MMF), Cyclophosphamide
University of Michigan Rogel Cancer Center, National Institutes of Health (NIH), National Center for Advancing Translational Sciences (NCATS)
Hematologic Diseases, Acute Leukemia in Remission, Chronic Myelogenous Leukemia - Chronic Phase, Chronic Myelogenous Leukemia, Accelerated Phase, Chronic Myelogenous Leukemia, Blastic Phase, Myelodysplastic Syndromes, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Non Hodgkin Lymphoma, Graft Vs Host Disease, Graft-versus-host-disease
06/25
06/26
ESCAPE1b, NCT01456988: Dasatinib and Cyclosporine in Patients With Chronic Myelogenous Leukemia (CML)

Recruiting
1
12
US
Dasatinib and Cyclosporine
University of Colorado, Denver, National Cancer Institute (NCI), The Leukemia and Lymphoma Society
Chronic Myelogenous Leukemia
12/12
09/13
NCT00547196: AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders

Completed
N/A
10
US
filgrastim, Busulfan, Busilvex, Cyclophosphamide, CTX, Cyclosporine, CsA, Fludarabine phosphate, Fludara, Melphalan, Alkeran, Mycophenolate Mofetil, MMF, allogeneic hematopoietic stem cell transplantation, AlloHCT, umbilical cord blood transplantation, total-body irradiation, TBI, Fractionated total body irradiation, FTBI
City of Hope Medical Center, National Cancer Institute (NCI)
Leukemia, Lymphoma, Myelodysplastic Syndromes
11/09
05/24

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