Online Trial Tracker - Larvol Sigma

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

cyclosporine / Generic mfg.

JCOG0907, jRCTs031180243: A Non-Randomized Validation Trial of a Therapy Incorporating Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Adult T-Cell Leukemia and Lymphoma

Completed

110

Japan

carboplatin - Generic mfg., cytarabine - Generic mfg., methotrexate - Generic mfg., prednisolone - Generic mfg., vincristine - Generic mfg., cyclophosphamide - Generic mfg., doxorubicin hydrochloride - Generic mfg., Cymerin (ranimustine) - Mitsubishi Tanabe, vindesine - Generic mfg., etoposide oral - Generic mfg., busulfan - Generic mfg., cyclosporine - Generic mfg., tacrolimus oral - Generic mfg., fludarabine oral - Generic mfg., prednisolone - Generic mfg., Lioplim (filgrastim) - Abbott, Neu-up (nartograstim) - Yakult Honsha, Granocyte (lenograstim) - Roche, Poteligeo (mogamulizumab-kpkc) - Kyowa Kirin

Saitama Medical University International Medical Center

Adult T-cell leukemia-lymphoma

2011-000088-28: A Randomized Phase III Study to Determine the Most Promising Postgrafting Immunosuppression for Prevention of Acute GVHD after Unrelated Donor Hematopoietic Cell Transplantation using Nonmyeloablative Conditioning for Patients with Hematologic Malignancies A Multi-Center Trial

Ongoing

300

Europe

Sirolimus, Mycophenolatmofetil, Cyclosporine, EU/1/01/171/007, EU/1/01/171/001, EU/1/96/005/001, EU/1/96/005/004, EU/1/96/005/005, Coated tablet, Oral liquid, Capsule, Tablet, Powder for concentrate for solution for infusion, Capsule, soft, Oral suspension, Concentrate and solvent for concentrate for solution for infusion, Rapamune, CellCept, Sandimmun

Fred Hutchinson Cancer Research Center

Graft versus host disease, Graft versus host disease is a process where donor cells may react against cells of your body causing inflammation that can involve the skin, liver and gastrointestinal system., Not possible to specify

ACTRN12605000380695: Induction Of Mixed Haematopoietic Chimerism In Patients Using Fludarabine, Low Dose Total Body Irradiation, Peripheral Blood Stem Cell Infusion And Post-Transplant Immunosuppression With Cyclosporine And Mycophenolate Mofetil

Active, not recruiting

A/Prof Durrant

Myelodysplastic syndromes., Myeloproliferative syndromes., Acute Leukemia with < 10% blasts., Amyloidosis, Hodgkins disease., Multiple Myeloma, Non-Hodgkins lymphoma, Chronic myeloid leukaemia, Chronic lymphocytic leukaemia, Renal cell carcinoma

NCT00544115: Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Active, not recruiting

260

busulfan, cyclophosphamide, cyclosporine, etoposide, fludarabine phosphate, melphalan, methotrexate, mycophenolate mofetil, sirolimus, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation

City of Hope Medical Center, National Cancer Institute (NCI)

Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Precancerous/Nonmalignant Condition

03/07

12/24

NCT00388102: Cyclophosphamide, Fludarabine, Total-Body Irradiation, and Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer or Other Disease

Recruiting

filgrastim, cyclophosphamide, cyclosporine, fludarabine phosphate, mycophenolate mofetil, cytogenetic analysis, flow cytometry, laboratory biomarker analysis, umbilical cord blood transplantation, total-body irradiation

Memorial Sloan-Kettering Cancer Center

Leukemia, Lymphoma, Myelodysplastic Syndromes

03/10

NCT00398346: Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

Recruiting

therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, fludarabine phosphate, tacrolimus, allogeneic hematopoietic stem cell transplantation, in vitro-treated peripheral blood stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation

National Heart, Lung, and Blood Institute (NHLBI)

12/10

NCT00066300: Allogeneic Peripheral Stem Cell Transplantation Followed By Donor Lymphocyte Infusions in Treating Patients With Hematologic Cancer

Active, not recruiting

graft-versus-tumor induction therapy, therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, fludarabine phosphate, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation, radiation therapy

National Heart, Lung, and Blood Institute (NHLBI)

Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms

NCT03434730: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation

Active, not recruiting

Total Body Irradiation, TBI, Cyclosporine, Sandimmune, Mycophenolate Mofetil, CellCept, Tocilizumab, Acemtra, Filgrastim, Granulocyte-Colony Stimulating Factor, Neupogen

Memorial Sloan Kettering Cancer Center

Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Myelodysplastic-Myeloproliferative Diseases, Myeloproliferative Disorder, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Leukemia

02/25

MoTD, NCT04888741 / 2019-002419-24: Methods of T Cell Depletion Trial

Recruiting

400

Europe

Thymoglobulin, ATG, Cyclophosphamide, Cyclosporine, Sirolimus, Mycophenolate Mofetil, MMF

University of Birmingham, IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)

Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia, Myelofibrosis

01/26

NCT05579769: A Phase II Pediatric Study of a Graft-VS.-Host Disease (GVHD) Prophylaxis Regimen With no Calcineurin Inhibitors After Day +60 Post First Allogeneic Hematopoietic Cell Transplant for Hematological Malignancies

Terminated

Ruxolitinib, (Jakafi®), Mesna, (Mesnex), Anti-thymocyte globulin (ATG), (Thymoglobulin®, rabbit ATG), Cyclosporine, (Gengraf), Cyclophosphamide, (Cytoxan), Fludarabine, (Fludara), Methotrexate, Total Body Irradiation (radiation treatment), TBI, Bone marrow infusion, Busulfan, Busulfex), Thiotepa, Triplex by Immunex, TESPA, TSPA

St. Jude Children's Research Hospital

Hematologic Malignancy, Myeloid Malignancy

05/24

NCT03842696: Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Recruiting

1/2

Vorinostat, Blood and Marrow Transplant (BMT), Tacrolimus (or cyclosporine), Methotrexate, Mycophenolate Mofetil (MMF), Cyclophosphamide

University of Michigan Rogel Cancer Center, National Institutes of Health (NIH), National Center for Advancing Translational Sciences (NCATS)

Hematologic Diseases, Acute Leukemia in Remission, Chronic Myelogenous Leukemia - Chronic Phase, Chronic Myelogenous Leukemia, Accelerated Phase, Chronic Myelogenous Leukemia, Blastic Phase, Myelodysplastic Syndromes, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Non Hodgkin Lymphoma, Graft Vs Host Disease, Graft-versus-host-disease

06/25

06/26

NCT00547196: AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders

Completed

N/A

filgrastim, Busulfan, Busilvex, Cyclophosphamide, CTX, Cyclosporine, CsA, Fludarabine phosphate, Fludara, Melphalan, Alkeran, Mycophenolate Mofetil, MMF, allogeneic hematopoietic stem cell transplantation, AlloHCT, umbilical cord blood transplantation, total-body irradiation, TBI, Fractionated total body irradiation, FTBI

City of Hope Medical Center, National Cancer Institute (NCI)

Leukemia, Lymphoma, Myelodysplastic Syndromes

11/09

05/24



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