Lymphoma, Non-Hodgkin  >>  cyclosporine  >>  Phase 2
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19 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
cyclosporine / Generic mfg.
NCT00003661: Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Completed
2
3
US
anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy
Roswell Park Cancer Institute
Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Neuroblastoma
11/99
03/06
NCT00005854: Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Completed
2
US
cyclophosphamide, cyclosporine, methotrexate, allogeneic bone marrow transplantation, in vitro-treated bone marrow transplantation, radiation therapy
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
 
10/00
NCT00024128: Peripheral Stem Cell Transplantation Followed By Infusion of White Blood Cells in Treating Patients With AIDS-Related Lymphoma

Withdrawn
2
0
US
anti-thymocyte globulin, therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation, radiation therapy
AIDS Malignancy Consortium, National Cancer Institute (NCI)
Lymphoma
03/03
03/03
NCT00003116: High-Dose Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Completed
2
66
US
filgrastim, busulfan, cyclophosphamide, cyclosporine, bone marrow ablation with stem cell support, peripheral blood stem cell transplantation
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
03/06
06/09
NCT00533923: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders

Completed
2
25
US
Cyclophosphamide; Fludarabine; Cyclosporin; CAMPATH-1H (Alemtuzumab); GM-CSF, Cytoxan;, Fludara;, Leukine;
Beth Israel Deaconess Medical Center, Bayer
AML, ALL, CLL, Myelodysplastic Syndrome, Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Multiple Myeloma, Aplastic Anemia, Myeloproliferative Disorder
01/07
01/07
NCT00005852: Bone Marrow Transplantation in Treating Patients With Severe Aplastic Anemia or Rejection of Previous Bone Marrow Transplant

Terminated
2
US
anti-thymocyte globulin, filgrastim, muromonab-CD3, cyclophosphamide, cyclosporine, methylprednisolone, allogeneic bone marrow transplantation
H. Lee Moffitt Cancer Center and Research Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
07/07
07/07
NCT00003335: Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Completed
2
44
US
anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy
Case Comprehensive Cancer Center, National Cancer Institute (NCI)
Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
11/07
01/12
NCT00317785: Total-Body Irradiation and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer and Other Diseases

Completed
2
50
US
cyclophosphamide, cyclosporine, methotrexate, mycophenolate mofetil, sirolimus, tacrolimus, pharmacological study, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Leukemia, Lymphoma, Myelodysplastic Syndromes
11/07
 
NCT00281879: Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer

Terminated
2
200
US
anti-thymocyte globulin, ATG, filgrastim, G-CSF, busulfan, carmustine, cyclophosphamide, cyclosporine, cytarabine, etoposide, fludarabine phosphate, melphalan, methotrexate, methylprednisolone, mycophenolate mofetil, tacrolimus, FK-506, peripheral blood stem cell transplantation, umbilical cord blood transplantation, radiation therapy
OHSU Knight Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Unusual Cancers of Childhood
02/08
03/08
NCT00027560: Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer

Completed
2
51
US
alemtuzumab, Campath, cyclosporine, fludarabine phosphate, melphalan, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
04/09
04/09
NCT00482053: Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT

Terminated
2
3
US
Autologous hematopoietic stem cell transplantation (auto-HSCT), Autologous peripheral blood progenitor cell (PBPC) transplantation, Allogeneic hematopoietic stem cell transplantation (allo-HSCT), Allogeneic peripheral blood progenitor cell (PBPC) transplantation, Total lymphoid irradiation (TLI), Rituximab, Rituxan, Mabthera, Carmustine, BCNU, BiCNU, Etoposide, Eposin, Etopophos, Vepesid, VP-16, Filgrastim, Granulocyte colony-stimulating factor (G-CSF, GCSF), Colony-stimulating factor 3 (CSF-3), Anti-thymocyte globulin (ATG), Cyclosporine, Cyclosporin, CSP, Mycophenolate mofetil (MMF), CellCept, Cyclophosphamide, Cytoxan, Neosar, Acetaminophen, Tylenol, Diphenhydramine, Benadryl, Hydrocortisone, Cortef, Methylprednisolone, Solu-Medrol
Stanford University
Lymphoma, B-cell, Lymphoma, Non-Hodgkin, Diffuse Large B-cell Lymphoma (DLBCL), Malignant Lymphoma, Non-Hodgkin
05/10
05/10
NCT00066300: Allogeneic Peripheral Stem Cell Transplantation Followed By Donor Lymphocyte Infusions in Treating Patients With Hematologic Cancer

Active, not recruiting
2
US
graft-versus-tumor induction therapy, therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, fludarabine phosphate, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation, radiation therapy
National Heart, Lung, and Blood Institute (NHLBI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
 
 
NCT00916045 / 2007-001657-26: Pilot Study of Unrelated Cord Blood Transplantation

Terminated
2
40
Europe
Thiotepa, Fludarabine, Intravenous busulphan, Busilvex, Thymoglobulin, Ciclosporin, Mycophenolate mofetil (MMF), Cyclophosphamide, Radiotherapy, Melphalan
King's College Hospital NHS Trust
Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Leukemia, Lymphoblastic, Acute, Lymphoma, Non-Hodgkin, Hodgkin Disease, Chronic Lymphocytic Leukemia
03/12
03/12
NCT00619645: Donor Peripheral Stem Cell Transplant, Fludarabine, and Busulfan in Treating Patients With Hematologic Cancers

Completed
2
8
US
busulfan, cyclosporine, fludarabine phosphate, mycophenolate mofetil, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation
University of California, Davis
Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
10/13
11/13
NCT00387959: Chemotherapy, Radiation Therapy, Rituximab, and Umbilical Cord Blood Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma

Checkmark P2 data in B-cell NHL
Nov 2011 - Nov 2011: P2 data in B-cell NHL
Completed
2
17
US
filgrastim, rituximab, cyclophosphamide, cyclosporine, fludarabine phosphate, mycophenolate mofetil, allogeneic hematopoietic stem cell transplantation, umbilical cord blood transplantation, total-body irradiation
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Leukemia, Lymphoma
04/14
04/14
NCT00425802: Chemotherapy, Total-Body Irradiation, Rituximab, and Donor Stem Cell Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

Completed
2
61
US
anti-thymocyte globulin, filgrastim, graft-versus-tumor induction therapy, rituximab, cyclophosphamide, cyclosporine, fludarabine phosphate, mycophenolate mofetil, nonmyeloablative allogeneic hematopoietic stem cell transplantation, total-body irradiation
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Leukemia, Lymphoma
10/16
10/16
NCT00365287: Combination Chemotherapy and Total-Body Irradiation Before Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer, Metastatic Breast Cancer, or Kidney Cancer

Completed
1/2
148
NA
anti-thymocyte globulin, cyclophosphamide, cyclosporine, fludarabine phosphate, mycophenolate mofetil, radiation therapy, umbilical cord blood transplantation
Masonic Cancer Center, University of Minnesota, National Cancer Institute (NCI)
Breast Cancer, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
12/05
12/05
NCT00816413: Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer

Withdrawn
1/2
0
NA
cyclosporine, Gengraf, Neoral, and Sandimmune, mycophenolate mofetil, CellCept, pentostatin, Nipent, cytogenetic analysis, fluorescence in situ hybridization, protein analysis, flow cytometry, immunoenzyme technique, laboratory biomarker analysis, reduced-intensity transplant conditioning procedure, nonmyeloablative allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation (PBSC), total-body irradiation
University of Nebraska, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Nonmalignant Neoplasm
02/10
02/10
NCT00245037: Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Completed
1/2
147
US
therapeutic allogeneic lymphocytes, busulfan, cyclosporine, fludarabine phosphate, mycophenolate mofetil, peripheral blood stem cell transplantation, Total Body Irradiation (TBI), Granulocyte colony-stimulating factor (G-CSF), Phenytoin, Methotrexate
OHSU Knight Cancer Institute, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition
08/15
08/15

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