| cyclosporine / Generic mfg. |
NCT00003661: Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer |
|
|
| Completed | 2 | 3 | US | anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy | Roswell Park Cancer Institute | Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Neuroblastoma | 11/99 | 03/06 | | |
NCT00005641: Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation |
|
|
| Terminated | 2 | | US | anti-thymocyte globulin, busulfan, cyclophosphamide, cyclosporine, leucovorin calcium, methotrexate, methylprednisolone, allogeneic bone marrow transplantation, in vitro-treated bone marrow transplantation, radiation therapy | H. Lee Moffitt Cancer Center and Research Institute, National Cancer Institute (NCI) | Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes | 09/00 | 09/00 | | |
NCT00003662: Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases |
|
|
| Completed | 2 | 90 | US | anti-thymocyte globulin, busulfan, cyclophosphamide, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy | Roswell Park Cancer Institute, National Cancer Institute (NCI) | Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Thymic Carcinoma | 01/01 | 01/01 | | |
CALCICLO, NCT00948727: Cyclosporine Dose Adjustment According to Calcineurin Activity After Allogeneic Hematopoietic Stem-cell Transplantation |
|
|
| Completed | 2 | 39 | Europe | Dose adaptation according to CN activity monitoring, Cyclosporine (CsA) | Assistance Publique - Hôpitaux de Paris, Agence de La Biomédecine | Hematopoietic Stem Cell Transplantation, Graft Versus Host Disease | 09/06 | 06/08 | | |
NCT00005852: Bone Marrow Transplantation in Treating Patients With Severe Aplastic Anemia or Rejection of Previous Bone Marrow Transplant |
|
|
| Terminated | 2 | | US | anti-thymocyte globulin, filgrastim, muromonab-CD3, cyclophosphamide, cyclosporine, methylprednisolone, allogeneic bone marrow transplantation | H. Lee Moffitt Cancer Center and Research Institute, National Cancer Institute (NCI) | Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes | 07/07 | 07/07 | | |
NCT00003335: Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer |
|
|
| Completed | 2 | 44 | US | anti-thymocyte globulin, busulfan, cyclosporine, melphalan, methylprednisolone, umbilical cord blood transplantation, radiation therapy | Case Comprehensive Cancer Center, National Cancer Institute (NCI) | Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases | 11/07 | 01/12 | | |
NCT00001873: The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers |
|
|
| Completed | 2 | 102 | US | Isolex 300i plus MoAbs | National Heart, Lung, and Blood Institute (NHLBI) | Chronic Lymphocytic Leukemia, Graft vs Host Disease, Hematologic Neoplasm, Multiple Myeloma, Myelodysplastic Syndrome | 12/07 | 06/17 | | |
NCT00775632: Alemtuzumab and Cyclosporine for the Prevention of Graft vs Host Disease After Stem Cell Transplants |
|
|
| Completed | 2 | 78 | Canada | Alemtuzumab, mycophenolate or cyclosporine and methotrexate | University Health Network, Toronto, Bayer | Graft Versus Host Disease, Bone Marrow Transplantation | 09/10 | 09/10 | | |
NCT00186628: Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD |
|
|
| Completed | 2 | 36 | US | Total lymphoid irradiation, TLI, Rituximab, Rituxan, Anti-thymoglobulin, rabbit (ATG, rabbit ATG), Cyclosporine, CSP, Sandimmune, Mycophenylate mofetil, MMF, CellCept, Filgrastim, G-CSF, Granulocyte-colony stimulating factor, Neupogen, Granisetron, Sancuso, Solumedrol, Medrol, Depo-Medrol, A-Methapred, Acetaminophen, Tylenol, Diphenhydramine, Benadryl, Hydrocortisone, Westcort | Stanford University, The Leukemia and Lymphoma Society, National Cancer Institute (NCI) | Leukemia, Mast-Cell, Mantle-cell Lymphoma | 11/10 | 12/10 | | |
NCT01135641 / 2009-016898-14: Study of First Line Treatment of Chronic Graft Versus Host Disease With the Association of Ciclosporine, Corticosteroids and Rituximab (Protocol R-GVHD) |
|
|
| Completed | 2 | 25 | Europe | Rituximab, Ciclosporine, Corticosteroids | Nantes University Hospital | Graft Versus Host Disease | 03/14 | 03/14 | | |
NCT00081055: OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignancies |
|
|
| Withdrawn | 2 | 0 | US | autologous expanded mesenchymal stem cells OTI-010, busulfan, cyclophosphamide, cyclosporine, methotrexate, peripheral blood stem cell transplantation, radiation therapy | Mesoblast International Sàrl, National Cancer Institute (NCI) | Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes | | | | |
NCT00054340: Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder |
|
|
| Completed | 1/2 | | US | anti-thymocyte globulin, busulfan, cyclophosphamide, cyclosporine, methotrexate, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation | Fred Hutchinson Cancer Center, National Cancer Institute (NCI) | Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases | | 09/06 | | |
NCT00002790: Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant |
|
|
| Withdrawn | 1/2 | 0 | US | cyclosporine, methotrexate, sirolimus | Fred Hutchinson Cancer Center, National Cancer Institute (NCI) | Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes | | | | |
