Genetic Diseases, Inborn  >>  cyclosporine  >>  Phase 2
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6 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
cyclosporine / Generic mfg.
NCT00029380: Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

Completed
2
30
US, Canada
Sangstat, Cyclophosphamide, Busulfan, Mycophenolate Mofetil, Cyclosporine, Cord Blood Transplantation
National Heart, Lung, and Blood Institute (NHLBI)
Hematologic Diseases, Anemia, Sickle Cell, Beta-Thalassemia, Hematopoietic Stem Cell Transplantation
08/06
08/06
NCT00301834: Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders

Completed
2
35
US
alemtuzumab, busulfan, cyclosporine, fludarabine phosphate, methotrexate, methylprednisolone, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, umbilical cord blood transplantation
University of California, San Francisco, National Cancer Institute (NCI)
Congenital Amegakaryocytic Thrombocytopenia, Diamond-blackfan Anemia, Leukemia, Myelodysplastic Syndromes, Severe Congenital Neutropenia
09/11
09/11
CYCLATOP, NCT02865356 / 2016-000467-16: Topical Solution for the Treatment of Atopic Dermatitis

Completed
2
36
Europe
Cyclosporine 5% solution, ciclosporin, Placebo, SP14019-F-02 Placebo
Spherium Biomed, Germans Trias i Pujol Hospital, Hospital del Mar, Hospital Sant Joan de Deu, Hospital Universitario Virgen Macarena, Hospital Universitario La Fe, Hospital General Universitario de Alicante, Fundación de Investigación Biomédica - Hospital Universitario de La Princesa, Hospital Universitario Virgen de la Victoria, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
Atopic Dermatitis
04/17
04/17
NCT00987480: Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine

Completed
2
45
US
Busulfan, fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine., CliniMACS device
Memorial Sloan Kettering Cancer Center, Boston Children's Hospital, Children's Hospital Medical Center, Cincinnati, Children's Hospital and Health System Foundation, Wisconsin, Rockefeller University, Fred Hutchinson Cancer Center
Aplastic Anemia, Leukemia, Myelodysplastic Syndrome
07/17
07/17
MUNCHR, NCT00578643: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease

Completed
2
15
US
Busulfan, Busulfex, Alemtuzumab, Campath, Cyclophosphamide, Cytoxan, Fludarabine, Fludara, Cyclosporine, Sandimmune, Stem Cell Infusion
Baylor College of Medicine
Chronic Granulomatous Disease
07/17
11/17
NCT02904772: Alipogene Tiparvovec for the Treatment of LPLD Patients

Withdrawn
2
0
US, Canada
alipogene tiparvovec, Glybera, Prednisolone, Cyclosporins, Mycophenolate mofetil
UniQure Biopharma B.V., Chiesi Farmaceutici S.p.A.
LPL Deficiency
06/20
09/20

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