Acute Myelocytic Leukemia  >>  cyclosporine  >>  Phase 1
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7 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
cyclosporine / Generic mfg.
NCT00005988: Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy

Completed
1
5
US
cyclophosphamide, cyclosporine, leucovorin calcium, methotrexate, methylprednisolone, in vitro-treated bone marrow transplantation, radiation therapy
Dana-Farber Cancer Institute, National Cancer Institute (NCI)
Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myeloma
06/01
03/02
NCT00004232: Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Completed
1
US
filgrastim, cyclosporine, methylprednisolone, prednisone, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation
Northwestern University, National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous/Nonmalignant Condition
10/02
10/02
NCT00376519: Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases

Terminated
1
3
US
cyclophosphamide, Cytoxan, cyclosporine, CSA, fludarabine phosphate, Fludara, mycophenolate mofetil, MMF, Treg cell infusion, umbilical cord blood transplantation, UCBT, total-body irradiation
Masonic Cancer Center, University of Minnesota
Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Secondary Myelofibrosis
03/08
03/08
NCT00080925: T-Cell-Depleted Allogeneic Stem Cell Transplantation After Immunoablative Induction Chemotherapy and Reduced-Intensity Transplantation Conditioning in Treating Patients With Hematologic Malignancies

Completed
1
20
US
filgrastim, graft-versus-tumor induction therapy, rituximab, therapeutic allogeneic lymphocytes, cyclophosphamide, cyclosporine, cytarabine, doxorubicin hydrochloride, etoposide, fludarabine phosphate, prednisone, vincristine sulfate, peripheral blood stem cell transplantation
National Institutes of Health Clinical Center (CC), National Cancer Institute (NCI)
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
 
12/10
NCT00513474: Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant

Completed
1
46
US
busulfan, cyclophosphamide, cyclosporin-A, etoposide, methotrexate, rasburicase, sirolimus, tacrolimus, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation, total-body irradiation, fludarabine, allopurinol
Massachusetts General Hospital
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
02/13
02/13
NCT01041508: Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.

Completed
1
18
US
Clofarabine, Clolar, Evoltra, Total Body Irradiation, TBI, Stem Cell Transplantation, SCT, Cyclosporine, Gengraf, Neoral, Sandimmune, Mycophenolate Mofetil, MMF
Therapeutic Advances in Childhood Leukemia Consortium, Genzyme, a Sanofi Company
Leukemia Lymphoblastic, Acute, Acute Myeloid Leukemia, Neoplasm Recurrent
08/14
08/14
NCT00686556: Total Marrow Irradiation for Refractory Acute Leukemia

Completed
1
12
US
cyclophosphamide, Cytoxan, cyclosporine, CSA, Fludarabine, Fludara, mycophenolate mofetil, MMF, total marrow irradiation, TMI, umbilical cord blood transplantation, umbilical cord blood, allogeneic hematopoietic stem cell transplantation, Granulocyte colony-stimulating factor, G-CSF, HLA-matched related donor bone marrow, mobilized peripheral blood stem cells
Masonic Cancer Center, University of Minnesota
Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, Multiple Myeloma
11/16
12/16

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