Uvadex/Therakos Photopheresis (methoxsalen/ECP) / Mallinckrodt |
2019-000894-22: Phase II multicenter study of UV irradiation with UvadexTM outside of the body plus standard steroid treatment for high risk acute Graft-versus-Host Disease Multizentrische Phase-II-Studie zur UV-Bestrahlung mit UvadexTM außerhalb des Körpers plus Standardbehandlung mit Steroiden bei akuter Spender-gegen-Empfänger-Erkrankung mit hohem Risiko |
|
|
| Not yet recruiting | 2 | 72 | Europe | Solution for blood fraction modification, UVADEX | Department of Stem Cell Transplantation - University Medical Center Hamburg-Eppendorf, Therakos, Inc. | New onset high risk acute GvHD following allogeneic SCT Neu auftretende akute GvHD mit hohem Risiko nach allogener SCT, New onset high risk acute Graft-versus-Host-Disease following allogeneic (of nonself origin) Stem Cell Transplantation Neu auftretende akute Spender-gegen-Empfänger-Erkrankung mit hohem Risiko nach Transplantation von Stammzellen, die nicht vom Patienten selbst stammen, Diseases [C] - Immune System Diseases [C20] | | | | |
| Not yet recruiting | 2 | 42 | Europe | Uvadex, Steroids | Central Hospital, Nancy, France | Graft Vs Host Disease | 09/25 | 01/26 | | |
NCT05157581: Extracorporeal Photopheresis in Sezary Syndrome |
|
|
| Recruiting | 2 | 15 | US | Extracorporeal photopheresis (ECP), ECP, photopheresis, Methoxsalen Injection, Uvadex | Oleg E. Akilov, MD, PhD, Mallinckrodt | Sezary Syndrome | 12/25 | 12/26 | | |
NCT04986605: Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis |
|
|
| Not yet recruiting | 2 | 15 | Canada | Extracorporeal Photopheresis (ECP), ECP, 8-mop, UVADEX | Lawson Health Research Institute, Mallinckrodt | Diffuse Cutaneous Systemic Sclerosis | 12/26 | 06/27 | | |
| Recruiting | 2 | 74 | US | UVADEX® (methoxsalen) Sterile Solution in conjunction with the THERAKOS® CELLEX Photopheresis, UVADEX® with THERAKOS® CELLEX Photopheresis, THERAKOS® CELLEX photopheresis system | Columbia University, Mallinckrodt, Inc. | Cutaneous T Cell Lymphoma, Mycosis Fungoides | 12/25 | 07/26 | | |
2021-002073-26: Extracorporeal photopheresis as treatment for immune related adverse events after immunotherapy Extrakorporale Photopherese zur Behandlung von immunvermittelten unerwünschten Ereignissen nach einer Immuntherapie |
|
|
| Not yet recruiting | 1/2 | 14 | Europe | UVADEX, Sterile concentrate, UVADEX | Medical Center - University of Freiburg, University of Freiburg, Faculty of Medicine, Therakos EMEA Ltd | Immune related adverse events induced by treatment with immune checkpoint inhibitors (monoclocanl antibodies against PD-1, PD-L1 or CTLA-4) Immunvermittelte unerwünschte Ereignisse, die durch eine Behandlung mit Immun-Checkpoint-Inhibitoren (monoklonale Antikörper gegen PD-1, PD-L1 oder CTLA-4) induziert wurden, Immune related adverse events induced by treatment with immunotherapy Immunvermittelte unerwünschte Ereignisse durch eine Behandlung mit einer Immuntherapie, Diseases [C] - Cancer [C04] | | | | |