BRAF, NCT03973918: Study of Binimetinib With Encorafenib in Adults With Recurrent V600-Mutated HGG |
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| Terminated | 2 | 5 | US | Encorafenib, Braftovi, Binimetinib, Mektovi, Research Bloods, Circulating Tumor DNA, Tumor Tissue | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI), Pfizer | High Grade Glioma, BRAF V600E, BRAF V600K, Anaplastic Astrocytoma, Anaplastic Pleomorphic Xanthoastrocytoma, Gliosarcoma, Glioblastoma | 04/22 | 10/23 | | |
NCT05957367: A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies |
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| Recruiting | 1/2 | 94 | US | DCC-3116, Ripretinib, QINLOCK, DCC-2618 | Deciphera Pharmaceuticals LLC, Pfizer | GIST | 03/27 | 06/27 | | |