zonisamide / Generic mfg. 
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15 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
zonisamide / Generic mfg.
2012-001884-64: A study of Standard and New Antiepileptic Drugs – SANAD-II.

Ongoing
4
1510
Europe
Sodium Valproate, Lamotrigine, Levetiracetam, Zonisamide, Tablet, Capsule, hard, Lamictal, Keppra, Zonegran
University of Liverpool, The Walton Centre NHS Foundation Trust, National Institute for Health Research (NIHR) Health Technology Assessment Program (HTA)
Epilepsy, Brain disorder, Diseases [C] - Nervous System Diseases [C10]
 
 
2018-000781-10: EFFICACY AND TOLERABILITY OF LOW versus STANDARD DAILY DOSES OF ANTIEPILEPTIC DRUGS IN NEWLY DIAGNOSED, PREVIOUSLY UNTREATED EPILEPSY Efficacia e tollerabilit¿ di basse dosi contro dosi standard dei farmaci antiepilettici in pazienti non trattati di nuova diagnosi.

Not yet recruiting
4
374
Europe
CARBAMAZEPINA, OXCARBAZEPINA, LAMOTRIGINA, LEVETIRACETAM, TOPIRAMATO, ACIDO VALPROICO, GABAPENTIN, ZONISAMIDE, CARBAMAZEPINA BASSA DOSE, OXCARBAZEPINA BASSA DOSE, LAMOTRIGINA BASSA DOSE, LEVETIRACETAM BASSA DOSE, TOPIRAMATO BASSA DOSE, ACIDO VALPROICO BASSA DOSE, GABAPENTIN BASSA DOSE, ZONISAMIDE BASSA DOSE, CARBAMAZEPINA, OXCARBAZEPINA, LAMOTRIGINA, LEVETIRACETAM, TOPIRAMATO, ACIDO VALPROICO, GABAPENTIN, ZONISAMIDE, CARBAMAZEPINA BASSA DOSE, OXCARBAZEPINA BASSA DOSE, LAMOTRIGINA BASSA DOSE, LEVETIRACETAM BASSA DOSE, TOPIRAMATO BASSA DOSE, ACIDO VALPROICO BASSA DOSE, GABAPENTIN BASSA DOSE, ZONISAMIDE BASSA DOSE, Tablet, Capsule, hard, TEGRETOL - 200 MG COMPRESSE A RILASCIO MODIFICATO 30 COMPRESSE, TOLEP - 300 MG COMPRESSE 50 COMPRESSE DIVISIBILI, LAMOTRIGINA DOC - 100 MG COMPRESSE DISPERSIBILI 56 COMPRESSE IN BLISTER ACLAR/PVC/AL, LEVETIRACETAM DOC - 500 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE, TOPIRAMATO DOC GENERICI - 100 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE IN BLISTER AL/AL, ACIDO VALPROICO SANDOZ - 300 MG COMPRESSE A RILASCIO PROLUNGATO30 COMPRESSE, GABAPENTIN MYLAN GENERICS - 400 MG CAPSULE RIGIDE 500 (5X100) CAPSULE IN BLISTER PVC/ALU CONFEZIONE OSPEDALIERA, ZONEGRAN - 100 MG CAPSULA RIGIDA USO ORALE BLISTER (PVC/ALL) 196 CAPSULE
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI, Ministero della Salute, Regione Lombardia
EPILEPSY EPILESSIA, EPILEPSY EPILESSIA, Diseases [C] - Nervous System Diseases [C10]
 
 
STANDLOW, NCT03689114: Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy

Active, not recruiting
4
374
Europe
Low dose carbamazepine, low carbamazepine, Standard dose carbamazepine, Standard carbamazepine, Low dose levetiracetam, Low levetiracetam, Standard dose levetiracetam, Standard levetiracetam, Low dose valproate, Low valproate, Standard dose valproate, Standard valproate, Low dose zonisamide, Low zonisamide, Standard dose zonisamide, Standard zonisamide, Low dose oxcarbazepine, Low oxcarbazepine, Standard dose oxcarbazepine, Standard oxcarbazepine, Low dose topiramate, Low topiramate, Standard dose topiramate, Standard topiramate, Low dose lamotrigine, Low lamotrigine, Standard dose lamotrigine, Standard lamotrigine, Low dose gabapentin, Low gabapentin, Standard dose gabapentin, Standard gabapentin
Mario Negri Institute for Pharmacological Research, Azienda Ospedaliera San Gerardo di Monza, Ministry of Health, Italy
Epilepsies, Partial
06/24
08/24
ChiCTR2100047311: An observational cohort study on the efficacy and safety of zonisamide as a first add-on treatment in focal epilepsy or focal to bilateral tonic clonic seizures

Recruiting
4
100
 
zonisamide Oral administration, once or twice daily. Titration period: the initial dose was 100 mg/maintenance dose was 200-400 mg/day, increased by 100 mg/day every 2 weeks, 8 to achieve the target dose, and the maintenance dose was 200-400 mg/day. Maintenance Phase: Zonisamide (ZNS) dose stable at 200 to
QiLu Hospital of Shandong University; Jiangxi Qingfeng Pharmaceutical Industry Co., Ltd., Jiangxi Qingfeng Pharmaceutical Co., Ltd.
Epilepsy
 
 
ACTRN12607000142437: Efficacy & Safety of Zonisamide in newly diagnosed partial epilepsy patients.

Not yet recruiting
3
582
 
Eisai Ltd, Pharmaceutical Research Associate Ltd.
Newly diagnosed partial epilepsy
 
 
NCT05205811: The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette

Recruiting
3
180
US
Bupropion, Wellbutrin, Zyban, Zonisamide, zonegran, Placebo bupropion, Placebo zonisamide, E-cigarette, JUUL
Rose Research Center, LLC, Foundation for a Smoke Free World INC
Smoking Cessation
02/24
06/24
NCT06361446: Zonisamide Versus Propranolol in Migraine

Recruiting
3
600
RoW
Zonisamide 50 MG, group A, Propranolol, group B
Kafrelsheikh University
Migraine
03/25
04/25
NCT06347497: Zonisamide Versus Topiramate in Migraine

Recruiting
3
600
RoW
Zonisamide 50 MG, group A, Topiramate 50 MG, group B
Kafrelsheikh University
Migraine
04/25
05/25
PINIHL-AET, NCT04768569: Noise-Induced Hearing Loss-Acute Exposure Treatment

Terminated
2
24
US
Zonisamide 100Mg Cap, Zonegran, ZNS, Placebo, microcrystalline cellulose
Washington University School of Medicine, University of Texas, Gateway Biotechnology, Inc., United States Department of Defense
Hearing Loss, Noise-Induced
09/23
09/23
NCT05134857: The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study

Recruiting
2
205
US
Zonisamide, Placebo
Washington State University
Alcohol Use Disorder (AUD)
08/26
08/26
NCT04182399: Role of Zonisamide in Advanced Parkinson's Disease (PD) in Egyptian Population: Pilot Study

Completed
N/A
69
RoW
Zonisamide Capsules, Convagran
Ain Shams University
Parkinson Disease
12/22
01/23
NCT04939675: Modification of Epilepsy Screen Questionnaire and Treatment Feasibility Evaluation

Not yet recruiting
N/A
40
NA
Zonisamide 100mg, Zonegran 100mg, Levetiracetam 500mg, Keppra 500mg, LamoTRIgine 50mg, Lamictal 50mg
National Taiwan University Hospital
Epilepsy
06/23
06/25
NCT05940935: The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy Operations

Completed
N/A
35
RoW
Arterial Blood Gas Base Deficit
Trakya University
Metabolic Acidosis, Antiepileptic Drugs, Craniotomy, Anesthesia Management
06/23
08/23
NCT06374966: Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy

Not yet recruiting
N/A
400
RoW
Zonisamide
Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou Children's Hospital, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, Jinhua Second Hospital, Ningbo Medical Center Lihuili Hospital, Ningbo Women & Children's Hospital, Yuyao People's Hospital, Huzhou Third People's Hospital, The Second Affiliated Hospital of Jiaxing University, Lishui Country People's Hospital
Epilepsies, Partial
09/25
12/25
EPIPOP, NCT03196466: Population Pharmacokinetics of Antiepileptic in Pediatrics

Recruiting
N/A
1000
Europe
Valproic acid, carbamazepine, phenobarbital, phenytoin, levetiracetam, lamotrigine, topiramate, oxcarbazepine, stiripentol, clobazam, brivaracétam, felbamate, lacosamide, rufinamide, gabapentine, pregabaline, sultiame, tiagabine, vigabatrine, mesuximide, primidone, perampanel, ethosuximide, zonisamide, cannabidiol, genetic polymorphisms
Assistance Publique - Hôpitaux de Paris
Epilepsy
06/26
06/26

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