| hydrocortisone / Generic mfg. |
ChiCTR-ICR-15007235: Dose hydrocortisone has effects on inhibiting inflammation and reducing hidden blood loss after total knee arthroplasty? |
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| Not yet recruiting | N/A | 30 | | low-dose hydrocortisone used after TKA | Department of Orthopaedics, West China Hospit; Department of Orthopaedics, West China Hospit, Natural Science Foundation of China | severe osteoarthritis of knee | | | | |
ChiCTR1800018138: Hydrocortisone, Vitamin C, and Thiamine for the treatment of septic shock |
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| Recruiting | N/A | 180 | | Hydrocortisone, Vitamin C, and Thiamine ;normal saline | The First College of Clinical Medical Science, China Three Gorges University, Yichang; None, Self-raised funds | septic shock | | | | |
HemaSur, NCT03688789: Hématologie Adulte Prevalence of Adrenal Insufficiency Post-chemotherapy Adrenocorticotropia in Adult Hematology |
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| Withdrawn | N/A | 200 | NA | Hydrocortisone supplementation | Rennes University Hospital | Haematological Malignancy | 07/21 | 12/22 | | |
NCT04486521: Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19 |
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| Recruiting | N/A | 860 | RoW | Interleukin 6 (IL6) Antagonist, Tocilizumab, Siltuximab, Interleukin 6 (IL6) Antagonist and corticosteroids, corticosteroid alone | King Faisal Specialist Hospital & Research Center, Society of Critical Care Medicine | Critical Illness, Corona Virus Infection, Cytokine Release Syndrome | 07/21 | 07/21 | | |
| Completed | N/A | 51 | Europe | Patient group, Remission control group, Bilateral surrenalectomy control group | University Hospital, Bordeaux | Cushing Disease | 06/22 | 06/22 | | |
ChiCTR2000040230: A randomized study on optimizing clinical outcomes of neonatal peri-cardiopulmoanry bypass period |
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| Recruiting | N/A | 240 | | methylprednisolone ;methylprdnisolone 15mg/kg twice ;hydrocortisone 75mg/kg twice ;none | Fuwai Hospital; Fuwai Hospital, Translational medicine fund of CAMS &PUMC | congenital heart disease | | | | |
ChiCTR1900024864: Experimental regimen of hydrocortisone, vitamin C and thiamine in the treatment of severe sepsis and septic shock |
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| Not yet recruiting | N/A | 250 | | routine treatment ;routine treatment +Vitamin C ;routine treatment +Hydrocortisone ;routine treatment +Vitamin B1 ;routine treatment+Vitamin C+Hydrocortisone+Vitamin B1 | Hebei Gereral Hospital; Hebei Gerneral Hospital, self-raised | Severe sepsis and septic shock | | | | |
| Completed | N/A | 30 | RoW | MiSaver | Honya Medical Inc, Chung Shan Medical University | Acute Myocardial Infarction | 12/23 | 12/23 | | |
| Recruiting | N/A | 100 | Europe | There is no specific intervention other than an individual changing their treatment as part of their usual care | Imperial College London | Adrenal Insufficiency | 12/25 | 12/25 | | |
NCT04456439: Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19) |
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| Available | N/A | | NA | Remestemcel-L, Hydrocortisone, Diphenhydramine, Benadryl® | Mesoblast International Sàrl | Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19) | | | | |
NCT04991259: To Evaluate the Safety and Efficacy of Preemptive Administration of Continuous Renal Replacement Therapy in Patients With Acute Liver Failure With Cerebral Edema |
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| Not yet recruiting | N/A | 60 | RoW | Continuous Renal Replacement Therapy (CRRT), Standard Medical Treatment | Institute of Liver and Biliary Sciences, India | Acute Liver Failure | 06/23 | 06/23 | | |
NCT05974410: Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients |
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| Available | N/A | | NA | AVM0703, Hydrocortisone, Proton pump inhibitor | AVM Biotechnology Inc | Glioblastoma, Squamous Cell Carcinoma, Hodgkin Lymphoma, Non-hodgkin Lymphoma, Breast Cancer, Prostate Cancer, Gastric Cancer, Ovarian Cancer, Acute Leukemia, Pancreatic Cancer, Spindle Cell Sarcoma, Cancer, Tumor, Solid, Tumor, Brain | | | | |
NCT05919121: Effect Of Hydrocortisone Phonophoresis Versus Iontophoresis In Patients With Subacromial Impingement Syndrome |
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| Recruiting | N/A | 60 | RoW | Therapeutic exercise, hydrocortisone phonophoresis, hydrocortisone iontophoresis | Horus University | Impingement Syndrome, Subacromial Impingement Syndrome | 08/23 | 09/23 | | |
| Completed | N/A | 32 | Europe | Continuous Glucose Monitoring | Imperial College Healthcare NHS Trust | Diabetes Mellitus, Type 1, Adrenal Insufficiency, Diabetes Mellitus Type 2 - Insulin-Treated | 08/23 | 09/23 | | |
| Not yet recruiting | N/A | 130 | Europe | Idroflog®, Study intervention, Sodium Hyaluronate 0.18% (Vismed®), Control intervention | Alfa Intes Industria Terapeutica Splendore s.r.l. | Dry Eye Disease | 10/23 | 12/23 | | |
NCT06171932: Comparison Of Efficacy Of Hydrocortisone And Methyl Prednisolone In Acute Severe Asthma |
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| Enrolling by invitation | N/A | 60 | RoW | Methylprednisolone,, Hydrocortisone | University of Karachi | Asthma Acute | 08/24 | 08/24 | | |
| Recruiting | N/A | 98 | Europe | Total pancreatectomy, Pancreatic anastomosis | Azienda Ospedaliera Universitaria Integrata Verona | Pancreatic Fistula | 12/23 | 12/25 | | |
PREMILOCAP, NCT05451264: Study of the Effect of Hydrocortisone Administered for the Prevention of Pulmonary Bronchodysplasia (PREMILOC Trial) on the Determinants of Systemic Blood Pressure in Children |
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| Recruiting | N/A | 80 | Europe | blood pressure measurement | Assistance Publique - Hôpitaux de Paris | Infant, Premature, Diseases | 06/24 | 10/24 | | |
NCT05750797: The Nationwide Real-world Status of Oral Corticosteroid Use in Patients With Asthma |
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| Not yet recruiting | N/A | 800000 | RoW | Oral corticosteroids | Joon Young Choi, Seoul St. Mary's Hospital, Hallym University Medical Center, Konkuk University Hospital | Asthma, Corticosteroid | 12/23 | 12/23 | | |
| Not yet recruiting | N/A | 100 | NA | Hydrocortisone-Lidocaine, Splint | National University Hospital, Singapore | De Quervain Syndrome | 02/24 | 02/24 | | |
ChiCTR2200058331: Evaluation of the predictive efficacy of the vasoactivity-positive inotropic drug score for the timing of hydrocortisone treatment for septic shock in term infants |
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| Not yet recruiting | N/A | 80 | | Shock was treated with a vasoactive drug score of 59 without hydrocortisone ;Shock was treated with a vasoactive drug score of 59 and hydrocortisone | Guangdong Maternal and Child Health Hospital; Guangdong Maternal and Child Health Hospital, Science and technology project of Guangzhou | neonatal shock | | | | |
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) |
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| Recruiting | N/A | 5000 | Canada, US | The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome | 09/26 | 09/27 | | |
| Recruiting | N/A | 230 | RoW | Early hydrocortisone, Normal saline placebo, Open-label hydrocortisone | Siriraj Hospital | Sepsis Severe, Shock, Septic | 06/25 | 09/25 | | |
| Recruiting | N/A | 120 | Europe | Screening and Confirmatory diagnostic test for primary aldosteronism | Aristotle University Of Thessaloniki | Atrial Fibrillation, Primary Aldosteronism | 09/24 | 09/24 | | |
| Recruiting | N/A | 1800 | Europe | Administration procedures | Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France, Versailles Saint-Quentin-en-Yvelines University, Université Paris-Saclay, Université Paris Est Créteil, Commissariat A L'energie Atomique, Beckman Coulter, Inc., Lumedix, Elice, Biothelis | Sepsis | 10/24 | 10/24 | | |
| Not yet recruiting | N/A | 16 | Europe | OD dual-release Hydrocortisone, Once-daily dual-release hydrocortisone, TID Hydrocortisone, Thrice-daily conventional immediate-release hydrocortisone | Vastra Gotaland Region, The Gothenburg Society of Medicine, Åke Wibergs Stiftelse, Sahlgrenska University Hospital, Sweden, Pilloxa | Diabetes Mellitus, Adrenal Insufficiency, Polyglandular Autoimmune Syndrome | 12/25 | 12/27 | | |
| Recruiting | N/A | 36 | Canada | Microneedling | Centre hospitalier de l'Université de Montréal (CHUM) | Burn Scar | 06/25 | 06/26 | | |
NCT02785224: Arterial Pressure and Stress-Dose Steroids in Cardiac Arrest. |
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| Not yet recruiting | N/A | 191 | Europe | Vasopressin Steroids Epinephrine, VSE | University of Athens, University of Thessaly | Cardiac Arrest | 12/26 | 12/26 | | |
