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49 Trials

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hydrocortisone / Generic mfg.
NCT00236925: Efficacy Study of Low-Dose Hydrocortisone Treatment for Fibromyalgia

Completed
1
30
Europe
Low dose Hydrocortisone, Cortisol, Placebo
Ludwig-Maximilians - University of Munich, University of Zurich
Fibromyalgia
05/07
06/07
NCT00928200: Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)

Terminated
1
1
US
Erwinase, Asparaginase, Elspar, Kidrolase, L-Asparaginase, Erwinia L-Asparaginase, Vincristine, Oncovin, Vincasar Pfs, Vincristine Sulfate, LCR, VCR, Dexamethasone, Decadron, Dexasone, Diodex, Hexadrol, Maxidex, Dexamethasone sodium phosphate, Dexamethasone acetate, Doxorubicin, Adriamycin, Rubex, Cytarabine, Cytosar-U, Ara-C, Arabinosylcytosine, Methotrexate, Otrexup, Rasuvo, Rheumatrex, Trexall, Amethopterin, Methotrexate Sodium, MTX, Triple Intrathecal Therapy, Dexrazoxane, Zinecard
Therapeutic Advances in Childhood Leukemia Consortium
Relapsed Acute Lymphoblastic Leukemia, Allergy to PEG e.Coli Asparaginase, Allergy to Native e.Coli Asparaginase
06/10
06/10
ELGAN BP, NCT00874393: Early Blood Pressure Management in Extremely Premature Infants

Completed
1
10
US
Dopamine, Hydrocortisone, Infusion Placebo, Syringe Placebo
NICHD Neonatal Research Network, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Hypotension, Blood Pressure
12/10
12/11
NCT01301677: Ultra Violet B Radiation (UVR) Study of Strontium Chloride Hexahydrate Hydrocortisone

Completed
1
47
Europe
Hydrocortisone, 2PX+, 2PX-
X-pert Med GmbH
Erythema, Pain
06/11
06/11
NCT00957320: Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)

Withdrawn
1
0
US
Sirolimus, PEG-asparaginase
Emory University
Acute Lymphoblastic Leukemia
08/12
08/12
NCT02777268: Comparison of Pharmacokinetics of Infacort® Versus Immediate-release Hydrocortisone

Completed
1
16
NA
Infacort, Hydrocortisone
Diurnal Limited, Simbec Research
Healthy Subjects
09/13
09/13
NCT01861002: A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

Completed
1
15
Canada, US, RoW
Azacytidine, 5 Azacytidine, Vidaza, Fludarabine, fludarabine phosphate, Fludara, 2-fluoro-ara-AMP, Oforta, Cytarabine, Cytosar-U, Ara-C, Arabinosylcytosine, cytosine arabinoside, Intrathecal (IT) Cytarabine, (See Cytarabine), Intrathecal Methotrexate (IT MTX), Otrexup, Rasuvo, Rheumatrex, Trexall, Amethopterin, Methotrexate Sodium
Therapeutic Advances in Childhood Leukemia Consortium, Gateway for Cancer Research
Lymphoblastic Leukemia, Acute, Childhood, Myelogenous Leukemia, Acute, Childhood
07/14
07/14
NCT01960530: An Investigational Study of Hydrocortisone

Completed
1
14
Europe
Hydrocortisone granules, Infacort, Hydrocortisone Tablet, Commerical supply, i.v. Hydrocortisone Injection, Dexamethasone, Non-IMP
Diurnal Limited, Simbec Research
Adrenal Insufficiency
11/14
11/14
NCT00849745: Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases

Terminated
1
4
US
Nonmyeloablative allogeneic stem cell transplant, Campath-1H
Duke University
Systemic Lupus Erythematosus, Systemic Sclerosis
07/15
07/15
2013-000260-28: An investigation into the administration of Infacort® in human adult volunteers

Completed
1
16
Europe
Infacort (0.5mg granule), Hydrocortisone (10mg Tablet), Infacort (2mg granules), Infacort (5mg granules), Infacort (10mg) (2x5mg granules), Hydrocortisone, Hydrocortisone
Diurnal Ltd, European Commission
Adrenal Insufficiency
 
09/13
NCT01887587: Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Terminated
1
5
US
MLN9708, Ixazomib, Vincristine, Oncovin, Doxorubicin, Doxil, hydroxydaunorubicin, Dexamethasone, Decadron, Dexasone, Solurex, Baycadron
Ehab L Atallah
Relapsed or Refractory Acute Lymphoblastic Leukemia, Relapsed or Refractory Lymphoblastic Lymphoma, Mixed Phenotype Acute Leukemia
02/16
02/16
NSS, NCT03670212: Investigation of Nicotine Seeking Behavior in Current Smokers

Completed
1
21
US
Yohimbine Hydrochloride, YOH, Hydrocortisone, HYD, Lactose Monohydrate Powder, Placebo
Wayne State University, National Institute on Drug Abuse (NIDA)
Cigarette Smoking
10/16
10/16
NCT02270788: Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Completed
1
10
US
Crenolanib, CP-868,596, IND 112201, Sorafenib, Sorafenib tosylate, BAY-43-9006, Nexavar®, methotrexate, hydrocortisone and cytarabine with leucovorin, Triple IT chemotherapy
St. Jude Children's Research Hospital, Arog Pharmaceuticals, Inc., Ohio State University
Acute Myeloid Leukemia
10/16
10/16
NCT02722200: Investigating the Central and Peripheral Mechanisms by Which Glucocorticoids Affect Hunger

Completed
1
28
US
hydrocortisone, saline
Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
07/17
07/17
NCT03178214: Bioavailability of Infacort When Administered Onto Food Compared to Direct Oral Administration

Completed
1
19
Europe
Infacort
Diurnal Limited, Simbec Research, EMAS Pharma, Voet Consulting, Brush Clinical Research Ltd., Medical Matters International Ltd
Adrenal Insufficiency
07/17
07/17
NCT02256865: Hormonal Mechanisms of Sleep Restriction

Completed
1
40
US
Ketoconazole, Nizoral, Hydrocortisone, Cortef, Cortril, Hydrocortone, Testosterone, AndroGel, Placebo for ketoconazole, Placebo for hydrocortisone, Placebo for testosterone
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Insulin Resistance
11/17
10/23
NCT01187810: Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL

Terminated
1
3
US
Fenretinide, N-(4-hydroxyphenyl) retinamide, 4-HPR, Cytarabine, Ara-C, Cytosine Arabinoside, Cytosar, Methotrexate, MTX, Amethopterin
South Plains Oncology Consortium
Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma
04/18
04/18
NCT02676323: Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Terminated
1
19
US
Panobinostat, LBH589, Fludarabine, Fludara®, Fludarabine phosphate, 2-fluoro-ara-AMP, Cytarabine, Cytosine arabinoside, Ara-C, Cytosar®, Intrathecal Triples, ITMHA, methotrexate/hydrocortisone/cytarabine, Leucovorin, Leucovorin calcium, Leucovorin rescue
St. Jude Children's Research Hospital
Acute Myeloid Leukemia, Myelodysplastic Syndrome
04/18
04/18
NCT03311932: A Study of Infacort® Versus Cortef® in Healthy Adult Male and Female Subjects

Completed
1
51
Europe
Infacort®, Cortef®
Diurnal Limited, Simbec Research, Brush Clinical Research Ltd., Voet Consulting, Bionical-Emas Pharma Ltd, Medical Matters International Ltd, Nichol Pharma Services Ltd.
Adrenal Insufficiency
07/18
07/18
NCT01422707: Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess

Withdrawn
1
0
US
Hydrocortisone, Cortef
University of Virginia
Hyperandrogenemia, Obesity, Polycystic Ovary Syndrome
07/18
07/18
NCT01422733: Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction

Withdrawn
1
0
US
Hydrocortisone, dexamethasone, Cosyntropin, Tetracosactide, rhCG, (Ovidrel)
University of Virginia
Hyperandrogenemia, Obesity, Polycystic Ovary Syndrome
07/18
07/18
NCT03554889: Immunotherapy of Advanced Cancer Using a Combination Nimotuzumab and NK Cells

Unknown status
1
21
RoW
NK Cell adaptive transfer, Nimotuzumab
Hangzhou Cancer Hospital, Shanghai bokang bioengineering co., LTD
Advanced Cancer, ADCC, NK Cell Mediated Immunity, Nimotuzumab, Adaptive Transfer
03/19
11/19
NCT03302416: CRF - Nociceptin Receptor Interactions

Completed
1
19
US
Hydrocortisone, [C-11]NOP-1A
University of Pittsburgh, National Institute on Drug Abuse (NIDA)
Healthy
06/19
06/19
NCT02843854: Safety and Efficacy of Allogeneic MSCs in Promoting T-regulatory Cells in Patients With Small Abdominal Aortic Aneurysms

Not yet recruiting
1
36
US
Intravenous infusion of Plasmalyte A (placebo), Intravenous infusion of 1 million allogeneic MSCs/kg, Intravenous infusion of 3 million allogeneic MSCs/kg
Michael Murphy
AAA, Abdominal Aortic Aneurysm, Vascular Disease, Peripheral Artery Disease
08/19
04/20
NCT02837432: The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression

Completed
1
192
US
Hydrocortisone acetate, Cortef, Placebo
Stanford University
Depression
12/19
11/20
NCT04016220: Nebulized Budesonide Combined With Systemic Corticosteroid in Acute Severe Asthma

Unknown status
1
60
RoW
Budesonide, normal saline
University of Monastir
Acute Asthma
12/19
05/20
NCT04435912: Hydrocortisone Per-treatment Decrease Side Effects of Protamine Sulfate

Completed
1
200
RoW
Hydrocortisone 200mg IV
University of Jordan
Blood Pressure, Heart Rate, Airway Pressure
04/20
06/20
NCT01265017: Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes

Withdrawn
1
0
US
Estradiol, medroxyprogesterone, hydrocortisone, GH, estradiol,medroxyprogesterone,hydrocortisone,growth hormone, Matching placebo, inert pills
Sansum Diabetes Research Institute
Type 1 Diabetes
06/20
06/20
RELPALL, NCT03515200: Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia

Terminated
1
12
US
Palbociclib Oral Capsule, Ibrance®, Intrathecal Triple Therapy, ITMHA, methotrexate/hydrocortisone/cytarabine, Dexamethasone, Decadron, Bortezomib, Velcade®, Dasatinib, Sprycel®, Doxorubicin, Adriamycin®, Ruxolitinib, Jakafi®
St. Jude Children's Research Hospital, Pfizer
Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission
07/20
07/20
NCT03194932: Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Completed
1
62
US
Venetoclax, Venclextra®, ABT-199, Cytarabine, Cytosine arabinoside, Ara-C, Cytosar®, Idarubicin, Idamycin PFS, Intrathecal Triple Therapy, ITMHA, methotrexate/hydrocortisone/cytarabine, Azacitidine, VIDAZA®
St. Jude Children's Research Hospital, Gateway for Cancer Research
Acute Myeloid Leukemia
10/20
06/22
NCT03792256: Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)

Active, not recruiting
1
12
US
Palbociclib, Cytarabine, Methotrexate, Hydrocortisone, Doxorubicin, Prednisolone, Vincristine, Pegaspargase, Prednisone
Children's Oncology Group
Leukemia, Lymphocytic, Lymphoblastic Lymphoma, T-cell Lymphoma, T-cell Leukemia, Recurrent Disease, Acute Leukemia
06/21
06/25
NCT03349281: Pevonedistat With VXLD Chemotherapy for Adolescent/Young Adults With Relapsed/Refractory ALL or Lymphoblastic NHL

Completed
1
6
US
Pevonedistat, TAK-924, MLN4924, Vincristine, Oncovin, VCR, LCR, Dexamethasone, Decadron, Hexadrol, Dexone, Dexameth, PEG-asparaginase, Oncaspar, Pegaspargase, Polyethylene Glycol Conjugated L-asparaginase-H, Doxorubicin, Adriamycin, Cytarabine, ARA-C, Methotrexate, MTX, Amethopterin, Hydrocortisone, Cortisol
Julio Barredo, MD, Takeda
Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia
08/21
10/22
NCT02846883: Safety and Efficacy of Allogeneic MSCs in Promoting T-regulatory Cells in Patients With Small Abdominal Aortic Aneurysms

Terminated
1
28
US
1 million MSCs/kg, 3 million MSCs/kg, Placebo, Plasmalyte A
VA Office of Research and Development
Abdominal Aortic Aneurysm
09/21
09/21
NCT04896489: Neuroimaging Mechanisms by Which Memory and Glucocorticoids Promote Risky Drinking

Completed
1
27
US
Hydrocortisone 20 MG, Placebo
Yale University
Alcohol Drinking, Drinking Behavior, Episodic Memory, Long-term Memory
03/22
03/22
NCT04148261: Epinephrine and Cortisol in Depression

Withdrawn
1
0
NA
Hydrocortisone Acetate (CORT), Cortef, Epinephrine Sulfate (EPI), Adrenalin, Placebo (PLB)
Stanford University
Depression
12/22
12/22
NCT03718234: Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia

Completed
1
11
US
Subcutaneous hydrocortisone, Hydrocortisone delivered via subcutaneous pump, Standard glucocorticoid therapy
University of Minnesota
Congenital Adrenal Hyperplasia, Hyperplasia, Adrenal Hyperplasia, Congenital Disorders, Adrenocortical Hyperfunction, Disorders of Sex Development, Urogenital Abnormalities, Genetic Diseases, Inborn, Steroid Metabolic Diseases, Inborn, Adrenal Gland Disease, Hydrocortisone
02/23
02/23
Gluco-Feed, NCT05167084: Acute Consequences Of Food-induced Glucocorticoid Secretion In Healthy Individuals

Completed
1
20
Europe
Metyrapone 250 mg Oral Tablets, Placebo 250 mg Tablets, Hydrocortisone 19,9mg s.c., pulsatile with a flow rate of 10μl/s, Placebo (0,9% NaCl solution)
Eleonora Seelig
Glucocorticoid Effect
06/23
06/23
SELCLAX, NCT04898894: Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
1
42
US
Venetoclax, Venclextra®, ABT-199, Selinexor, KPT-330, Cytarabine, Cytosine arabinoside, Ara-C, Cytosar®, Fludarabine, Fludara®, Fludarabine phosphate, 2-fluoro-ara-AMP, Filgrastim, G-CSF, Methotrexate, MTX, amethopterin, Trexall®, methotrexate/hydrocortisone/cytarabine, ITMHA, Intrathecal triples
St. Jude Children's Research Hospital, Karyopharm Therapeutics Inc, AbbVie, Gateway for Cancer Research
Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia
07/23
07/25
MsSCORE, NCT03237689: Effects of Glucocorticoids on Cognition in HIV-infected Women

Completed
1
136
US
Hydrocortisone, Placebo Oral Tablet
Johns Hopkins University, National Institute of Mental Health (NIMH)
Hiv
09/23
09/23
MK-5684-001, NCT06136598: A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Active, not recruiting
1
14
RoW
Opevesostat, MK-5684, Dexamethasone, Dexamethasone acetate, Fludrocortisone, Fludrocortisone acetate, Hydrocortisone, Hydrocortisone acetate
Merck Sharp & Dohme LLC, Orion Corporation, Orion Pharma
Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer
09/25
03/27
NCT06177067: Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
1
24
US
Revumenib, SNDX-5613, Venetoclax, Venclextra®, Azacitidine, VIDAZA®, 5-azacitidine, intrathecal (IT) chemotherapy, ITMHA, methotrexate/hydrocortisone/cytarabine, Cytarabine, Ara-C, Cytosar®, Methotrexate, MTX, Trexall®
St. Jude Children's Research Hospital, Syndax Pharmaceuticals
Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Acute Leukemia of Ambiguous Lineage
01/26
07/26
NCT02303821 / 2014-001633-84: Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Completed
1
130
Europe, Canada, US, RoW
Carfilzomib, PR-171, PR171, Kyprolis® (carfilzomib) for Injection, Dexamethasone, Mitoxantrone, PEG-asparaginase, Vincristine, Intrathecal (IT) Methotrexate, Intrathecal Triple Therapy (Intrathecal Cytarabine, Hydrocortisone, and Methotrexate), 6-Mercaptopurine, Cyclophosphamide, Cytarabine, Daunorubicin
Amgen, Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) - Study Design & Execution Collaborator, Innovative Therapies For Children with Cancer Consortium
Acute Lymphoblastic Leukemia (ALL)
06/24
06/24
COBRAS, NCT06430580: Cannabinoids and Biological Reactivity to Stress

Not yet recruiting
1
36
NA
Hydrocortisone Oral, Yohimbine Hydrochloride, Cornstarch Placebo 20mg, Cornstarch Placebo 54mg
Auburn University, Wayne State University, National Institute on Drug Abuse (NIDA)
Cannabis Use Disorder
03/26
03/26
DUOC for MS, NCT04943289: Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Recruiting
1
20
US
DUOC-01
Joanne Kurtzberg, MD
Primary Progressive Multiple Sclerosis
08/25
08/25
NCT05919992: The Role of Glucocorticoids to Maintain Energy Homeostasis During Starvation (Gluco-Starve)

Completed
1
24
Europe
Metyrapone 250 mg Oral Tablets, Hydrocortisone 19.9mg s.c., pulsatile with a flow rate of 10μl/s, Placebo 250 mg Tablets, Placebo (0,9% NaCl solution)
Eleonora Seelig
Glucocorticoid Effect
07/24
07/24
NCT02574910: Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1

Suspended
1
36
US
Abiraterone acetate, Zytiga
University of Texas Southwestern Medical Center, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), University of Michigan, Children's Hospital Los Angeles
Congenital Adrenal Hyperplasia
01/25
01/25
NCT05476770: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Recruiting
1
54
US, RoW
Tagraxofusp, Elzonris, Fludarabine, Cytarabine, Cytosar, Dexamethasone, Decadron, Vincristine, Oncovin, Azacitidine, AZA, Vidaza, Methotrexate, MTX, Amethopterin, Cytarabine IT, Hydrocortisone
Therapeutic Advances in Childhood Leukemia Consortium
Hematologic Malignancy, AML, ALL, BPDCN, MDS, Lymphoblastic Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell, Hodgkin Lymphoma, Mixed Phenotype Acute Leukemia, Acute Undifferentiated Leukemia
11/25
11/27
MK-5684-005, NCT06104449: A Study of Opevesostat (MK-568)4 in Japanese Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)

Active, not recruiting
1
6
Japan
Opevesostat, MK-5684, Dexamethasone, Decadron, Fludrocortisone acetate, Hydrocortisone
Merck Sharp & Dohme LLC, Orion Corporation, Orion Pharma
Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer
01/26
01/26
NCT05008146: Imaging CRF X NOP Interactions in CUD

Recruiting
1
80
US
Baseline [C-11]NOP-1A PET Scan, Hydrocortisone, Post-hydrocortisone [C-11]NOP-1A PET Scan
Rajesh Narendran, National Institute on Drug Abuse (NIDA)
Cocaine Use Disorder
09/28
09/28

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