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26 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
hydrocortisone / Generic mfg.
ReMIND, NCT01095172 / 2009-017066-23: RituxiMab INDuction in Renal Transplantation

Checkmark BTS 2016: ReMIND
Mar 2016 - Mar 2016: BTS 2016: ReMIND
Active, not recruiting
4
100
Europe
Rituximab, Mabthera, Tacrolimus, Advagraf, Adoport, Prograf, Mycophenylate mofetil, MMF, Cellcept, Hydrocortisone, Prednisolone
Guy's and St Thomas' NHS Foundation Trust, Astellas Pharma Europe Ltd.
Function of Renal Transplant
10/20
10/22
2018-001502-28: Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study)

Not yet recruiting
3
55
Europe
Hydrocortisone, Prednisolone, Tablet, Hydrocortisone, Prednisolone
Imperial College London, National Institute For Health Research
Adrenal insufficiency, Condition in which an individual is unable to produce adequate levels of steroid hormones, Body processes [G] - Physiological processes [G07]
 
 
MK-5684-004, NCT06136650: A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA

Recruiting
3
1500
Europe, Japan, US, RoW
Opevesostat, MK-5684, Dexamethasone, Fludrocortisone acetate, Hydrocortisone, Abiraterone acetate, Zytiga, Yonsa, Prednisone acetate, Enzalutamide, Xtandi
Merck Sharp & Dohme LLC, Orion Corporation, Orion Pharma
Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms
12/30
12/30
MK-5684-003, NCT06136624: Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC

Recruiting
3
1200
Europe, Canada, Japan, US, RoW
Opevesostat, MK-5684, Abiraterone acetate, ZYTIGA, YONSA, Enzalutamide, XTANDI, Hydrocortisone, Fludrocortisone acetate, Prednisone, Dexamethasone
Merck Sharp & Dohme LLC, Orion Corporation, Orion Pharma
Prostate Cancer Metastatic
08/28
08/28
DFCI 16-001, NCT03020030: Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents

Active, not recruiting
3
560
Canada, US
Pegaspargase, Erwinia asparaginase, ERWINAZE®, ERWINIA CHRYSANTHEMI, ERWINASE®, Cyclophosphamide, CYTOXAN, CYTARABINE, CYTOSINE ARABINOSIDE, ARA-C, CYTOSAR®, DASATINIB, DEXAMETHASONE, DECADRON®, HEXADROL®,, DEXONE®,, DEXAMETH®, Dexrazoxane, Zinecard, Doxorubicin, ADRIAMYCIN®, ETOPOSIDE, VePesid, HYDROCORTISONE, LEUCOVORIN CALCIUM, MERCAPTOPURINE, 6-MP, METHOTREXATE, NELARABINE, Vincristine, Oncovin
Dana-Farber Cancer Institute, Servier
Acute Lymphoblastic Leukemia, Pediatric
11/24
11/34
VAST-A, NCT05139849: VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial

Recruiting
3
1276
Europe
Vasopressin; Methylprednisolone; Hydrocortisone, Sodium chloride
Tiohundra AB, Sahlgrenska University Hospital, Sweden, Stockholm South General Hospital
Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical Trial
01/27
04/27
NCT06390319: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Not yet recruiting
2
145
US
Dexamethasone, Decadron, Hexadrol®, Vincristine, Vincristine Sulfate, Oncovin, Daunorubicin, Daunomycin, Calaspargase pegol, ASPARLAS, Dasatinib, Sprycel®, Venetoclax, Venclexta®, Bortezomib, Velcade®, Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine), IT MHA, Cyclophosphamide, Cytoxan®, Cytarabine, Ara-C, Cytosine arabinoside, Mercaptopurine, 6-MP, Nelarabine, Arranon, Atriance, Methotrexate, Trexall®, Thioguanine, 6-thioguanine, Tabloid®
St. Jude Children's Research Hospital, AbbVie
T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma, Mixed Phenotype Acute Leukemia
12/27
12/33
NCT03913559: Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

Recruiting
2
32
US
Inotuzumab ozogamicin, Besponsa, CMC-544, Methotrexate, Trexall®, Hydrocortisone, Cortisol, Cytarabine, Ara-C, Diphenhydramine, Benadryl, Acetaminophen, Tylenol, Methylprednisolone, Solu-Medrol
St. Jude Children's Research Hospital, Pfizer
Acute Lymphoblastic Leukemia
12/24
01/25
NCT05656248: Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms

Recruiting
2
25
US
CPX-351, Vyxeos®, cytarabine/daunorubicin liposomal, MHA, methotrexate/hydrocortisone/cytarabine, Allogeneic Hematopoietic Stem Cell Transplantation, HSCT, Stem Cell Transplantation
St. Jude Children's Research Hospital, Jazz Pharmaceuticals
Myeloid Neoplasm
08/25
08/28
T2017-002, NCT03817320 / 2019-001947-28: PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Active, not recruiting
1/2
31
US, RoW
Ixazomib, Vincristine, Dexamethasone, Asparaginase, Doxorubicin, Methotrexate (IT), Triple IT (Methotrexate, Hydrocortisone, Cytarabine), Leucovorin
Therapeutic Advances in Childhood Leukemia Consortium, Takeda, Children's Hospital Los Angeles
ALL, Childhood, Lymphoblastic Lymphoma, Childhood, Lymphoblastic Leukemia, Acute, Childhood
12/24
06/25
NCT05192889: Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

Active, not recruiting
1/2
98
US
Venetoclax, Venclextra®, ABT-199, Navitoclax, ABT-263, Dexamethasone, Decadron®, Hexadrol®, Dexameth®, Vincristine, Vincristine sulfate, Oncovin®, Calaspargase Pegol, Asparlas, Dasatinib, Sprycel®, Cytarabine, Ara-C, Cytosar-U®, Blinatumomab, Blincyto®, Methotrexate, MTX, Trexall®, amethopterin, Mercaptopurine, 6-MP, Purinethol®, Cyclophosphamide, Cytoxan®, Etoposide, VP-16, Vepesid®, Leucovorin, Folinic acid, Intrathecal Triples, ITMHA, methotrexate/hydrocortisone/cytarabine, Pegaspargase, Oncaspar®, PEG-asparaginase, PEG-L-asparaginase, Erwinia asparaginase, Erwinase®, Radiation, Irradiation
St. Jude Children's Research Hospital, AbbVie
Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia
08/25
07/29
NCT04501614 / 2019-002549-39: A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Active, not recruiting
1/2
68
Europe, US, RoW
Ponatinib, Ponatinib AAF, Chemotherapy Agents
Takeda, Takeda Development Center Americas, Inc.
Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL), Philadelphia Chromosome-Like ALL (Ph-like ALL)
12/24
01/27
NCT04029688 / 2018-004579-11: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

Active, not recruiting
1/2
38
Europe, Canada, US
Idasanutlin, RG7388, Venetoclax, RG7601, GDC-0199, ABT-199, Cyclophosphamide, Topotecan, Fludarabine, Cytarabine, Intrathecal Chemotherapy
Hoffmann-La Roche
Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Neuroblastoma, Solid Tumors
06/24
12/25
NCT03793478 / 2016-002919-18: Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

Recruiting
1/2
65
Europe, Canada, US, RoW
Quizartinib, Quizartinib dihydrochloride, Vanflyta, Fludarabine, Cytarabine, Intrathecal (IT) triple chemotherapy prophylaxis, Etoposide
Daiichi Sankyo, Inc., Innovative Therapies For Children with Cancer Consortium, Children's Oncology Group
Acute Myeloid Leukemia
05/27
05/27
CD2 SCD, NCT06078696: Siplizumab for Sickle Cell Disease Transplant

Recruiting
1/2
18
US
Siplizumab, TCD601 (Siplizumab), Exchange Transfusion, Total Body Irradiation, TBI, Stem Cell Infusion, Cyclophosphamide 50mg, Cytoxan, Cytoxan Lyophilized, Mesna, Mesnex, Sirolimus Oral Tablet, Rapamycin, Rapamune, Rituximab or Biosimilar, Riabni, Rituxan, Ruxience, Truxima
Markus Mapara, ITB-Med LLC
Anemia, Sickle Cell
07/28
07/29
SELCLAX, NCT04898894: Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
1
42
US
Venetoclax, Venclextra®, ABT-199, Selinexor, KPT-330, Cytarabine, Cytosine arabinoside, Ara-C, Cytosar®, Fludarabine, Fludara®, Fludarabine phosphate, 2-fluoro-ara-AMP, Filgrastim, G-CSF, Methotrexate, MTX, amethopterin, Trexall®, methotrexate/hydrocortisone/cytarabine, ITMHA, Intrathecal triples
St. Jude Children's Research Hospital, Karyopharm Therapeutics Inc, AbbVie, Gateway for Cancer Research
Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia
07/23
07/25
MK-5684-001, NCT06136598: A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Recruiting
1
14
RoW
Opevesostat, MK-5684, Dexamethasone, Dexamethasone acetate, Fludrocortisone, Fludrocortisone acetate, Hydrocortisone, Hydrocortisone acetate
Merck Sharp & Dohme LLC, Orion Corporation, Orion Pharma
Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer
04/26
10/27
NCT06177067: Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
1
24
US
Revumenib, SNDX-5613, Venetoclax, Venclextra®, Azacitidine, VIDAZA®, 5-azacitidine, intrathecal (IT) chemotherapy, ITMHA, methotrexate/hydrocortisone/cytarabine, Cytarabine, Ara-C, Cytosar®, Methotrexate, MTX, Trexall®
St. Jude Children's Research Hospital, Syndax Pharmaceuticals
Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Acute Leukemia of Ambiguous Lineage
01/26
07/26
NCT02303821 / 2014-001633-84: Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Active, not recruiting
1
130
Europe, Canada, US, RoW
Carfilzomib, PR-171, PR171, Kyprolis® (carfilzomib) for Injection, Dexamethasone, Mitoxantrone, PEG-asparaginase, Vincristine, Intrathecal (IT) Methotrexate, Intrathecal Triple Therapy (Intrathecal Cytarabine, Hydrocortisone, and Methotrexate), 6-Mercaptopurine, Cyclophosphamide, Cytarabine, Daunorubicin
Amgen, Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) - Study Design & Execution Collaborator, Innovative Therapies For Children with Cancer Consortium
Acute Lymphoblastic Leukemia (ALL)
07/24
07/24
MK-5684-005, NCT06104449: A Study of Opevesostat (MK-568)4 in Japanese Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)

Active, not recruiting
1
6
Japan
Opevesostat, MK-5684, Dexamethasone, Decadron, Fludrocortisone acetate, Hydrocortisone
Merck Sharp & Dohme LLC, Orion Corporation, Orion Pharma
Prostatic Neoplasms, Metastatic Castration-Resistant Prostate Cancer
01/26
01/26
MiSaver®, NCT06353958: Stem Cell Treatment for Acute Myocardial Infarction

Completed
N/A
30
RoW
MiSaver
Honya Medical Inc, Chung Shan Medical University
Acute Myocardial Infarction
12/23
12/23
NCT04456439: Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19)

Available
N/A
NA
Remestemcel-L, Hydrocortisone, Diphenhydramine, Benadryl®
Mesoblast International Sàrl
Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19)
 
 
NCT05974410: Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

Available
N/A
NA
AVM0703, Hydrocortisone, Proton pump inhibitor
AVM Biotechnology Inc
Glioblastoma, Squamous Cell Carcinoma, Hodgkin Lymphoma, Non-hodgkin Lymphoma, Breast Cancer, Prostate Cancer, Gastric Cancer, Ovarian Cancer, Acute Leukemia, Pancreatic Cancer, Spindle Cell Sarcoma, Cancer, Tumor, Solid, Tumor, Brain
 
 
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Recruiting
N/A
5000
Canada, US
The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab
Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
09/26
09/27
RECORDS, NCT04280497 / 2020-000296-21: Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis

Recruiting
N/A
1800
Europe
Administration procedures
Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France, Versailles Saint-Quentin-en-Yvelines University, Université Paris-Saclay, Université Paris Est Créteil, Commissariat A L'energie Atomique, Beckman Coulter, Inc., Lumedix, Elice, Biothelis
Sepsis
10/24
10/24
INSCORT, NCT05716607: Treatment Study in Patients Treated With Both Insulin & Hydrocortisone

Not yet recruiting
N/A
16
Europe
OD dual-release Hydrocortisone, Once-daily dual-release hydrocortisone, TID Hydrocortisone, Thrice-daily conventional immediate-release hydrocortisone
Vastra Gotaland Region, The Gothenburg Society of Medicine, Åke Wibergs Stiftelse, Sahlgrenska University Hospital, Sweden, Pilloxa
Diabetes Mellitus, Adrenal Insufficiency, Polyglandular Autoimmune Syndrome
12/25
12/27

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