CNS Disorders  >>  hydrocortisone 
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10 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
hydrocortisone / Generic mfg.
2006-006089-40: High dose corticosteroid pulses in treatment-resistant depression : a randomized double-blind placebo-controlled pilot study

Ongoing
4
40
Europe
hydrocortisone,
University Hospitals Bristol NHS Foundation Trust
Resistant depression
 
 
2017-003705-17: Hydrocortisone as co-treatment to prevent neuropsychiatric adverse effects of dexamethasone. Hydrocortison als co-medicatie om nadelige neuropsychiatrische effecten van dexamethason tegen te gaan.

Not yet recruiting
4
180
Europe
Tablet, Hydrocortison Tiofarma 20 mg, tabletten
LUMC, ZonMw
Neuropsychiatric adverse effects which can be caused by dexamethasone. For example delirium, anxiety, depression, mania and psychosis. But also cognitive impairment and sleep disturbance. Psychiatrische klachten die kunnen ontstaan bij dexamethason gebruik, zoals delier, angst, depressie, manie en psychoses. Ook cognitieve klachten en slaap klachten., Neuropsychiatric adverse effects which can be caused by dexamethasone. For example delirium, anxiety, depression, mania and psychosis. But also cognitive impairment and sleep disturbance. Psychiatrische klachten die kunnen ontstaan bij dexamethason gebruik, zoals delier, angst, depressie, manie en psychoses. Ook cognitieve klachten en slaap klachten., Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
ROSES, NCT06018727: Role Of Sensitivity to neuroEndocrine Systems in Social Decisions

Withdrawn
4
104
US
Hydrocortisone, Cortef, Yohimbine, Yohimbine Hydrochloride, Placebo, Sugar pill
University of North Carolina, Chapel Hill
Borderline Personality Disorder
07/25
07/25
EVANTHEA, NCT05894954: Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment

Recruiting
3
72
US
Precision Medicine Approach, ReCODE, Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises, Standard-of-Care, Academy of Neurology practice guidelines, Lifestyle including diet, exercise, stress management
Alzheimer's Prevention and Reversal Project, Inc., Four Winds Foundation
Mild Cognitive Impairment, Dementia, Mild
03/25
09/25
MOGwAI, NCT05349006: Azathioprine in MOGAD

Not yet recruiting
3
126
Europe
Azathioprine, Placebo
Hospices Civils de Lyon
Central Nervous System Inflammation, MOG-IgG Associated Disease
01/26
01/29
ACTRN12622000530729: Autologous Stem Cell Transplant in other Neuro-Inflammatory diseases

Not yet recruiting
2
20
 
St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney
Neuromyelitis Optica, Stiff Person Syndrome, Myasthenia Gravis, Central Nervous System Vasculitis
 
 
NCT04924166: PTSD Prevention Using Oral Hydrocortisone

Recruiting
2
220
US, RoW
Placebo, Hydrocortisone, HCORT
Rachel Yehuda, James J. Peters Veterans Affairs Medical Center, The Chaim Sheba Medical Center
PTSD, Acute Stress Disorder, Trauma-related Stressor
04/25
04/25
DIRECT, NCT06446245: Adjunctive Doxycycline for Central Nervous System Tuberculosis

Not yet recruiting
2
200
RoW
Doxycycline, Placebo, Anti Tuberculosis Drug, Adjunctive corticosteroid
National University Hospital, Singapore, National Medical Research Council (NMRC), Singapore
Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology), Tuberculosis, Central Nervous System, Tuberculosis; Meningoencephalitis (Etiology)
11/27
12/27
DUOC for MS, NCT04943289: Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis

Recruiting
1
20
US
DUOC-01
Joanne Kurtzberg, MD
Primary Progressive Multiple Sclerosis
08/25
08/25
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Recruiting
N/A
5000
Canada, US
The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab
Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
09/26
09/27

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