| hydrocortisone / Generic mfg. |
2017-001915-35: GLUCOCORTICOID HIGH-DOSE VS. GLUCOCORTICOID REPLACEMENT THERAPY IN IMMUNE CHECKPOINT INHIBITOR ASSOCIATED INFLAMMATION OF THE PITUITARY GLAND: AN OPEN, RANDOMIZED PILOT STUDY |
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| Ongoing | 4 | 20 | Europe | Hydrocortisone, Prednisolone, n.a., Tablet, Hydrocortone, Aprednislon | Medical University of Graz, Medical University of Graz | Immune regulatory antibodies (e.g. ipilimumab, pembrolizumab and nivolumab) inhibiting immunological checkpoints are increasingly used to treat various oncological entities. Potential side effects of are immune-related adverse events such as hypophysitis, affecting up to 10–15% of patients receiving ipilimumab. Hypophysitis manifests mostly in the form of multiple anterior pituitary hormone deficiencies (mostly central hypothyroidism and central adrenal insufficiency)., Immune regulatory antibodies are novel drugs used to treat various cancers. Potential side effects include inflammation of the pituitary gland, manifesting in the form of hormone deficiencies., Diseases [C] - Hormonal diseases [C19] | | | | |
| Not yet recruiting | 3 | 126 | Europe | Azathioprine, Placebo | Hospices Civils de Lyon | Central Nervous System Inflammation, MOG-IgG Associated Disease | 01/26 | 01/29 | | |
| Not yet recruiting | 2 | 20 | | | St Vincent's Hospital, Sydney , St Vincent's Hospital,Sydney | Neuromyelitis Optica, Stiff Person Syndrome, Myasthenia Gravis, Central Nervous System Vasculitis | | | | |
| Recruiting | 2 | 86 | US | Hydrocortisone, Cortef, Cortisol, Hydrocort, Placebo, Normal Saline, 0.9% NACL | Beth Israel Deaconess Medical Center | Pancreatitis, Pancreatitis, Acute, Corticosteroid, Hydrocortisone | 01/27 | 04/27 | | |
ChiCTR-ICR-15007235: Dose hydrocortisone has effects on inhibiting inflammation and reducing hidden blood loss after total knee arthroplasty? |
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| Not yet recruiting | N/A | 30 | | low-dose hydrocortisone used after TKA | Department of Orthopaedics, West China Hospit; Department of Orthopaedics, West China Hospit, Natural Science Foundation of China | severe osteoarthritis of knee | | | | |
NCT04486521: Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19 |
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| Recruiting | N/A | 860 | RoW | Interleukin 6 (IL6) Antagonist, Tocilizumab, Siltuximab, Interleukin 6 (IL6) Antagonist and corticosteroids, corticosteroid alone | King Faisal Specialist Hospital & Research Center, Society of Critical Care Medicine | Critical Illness, Corona Virus Infection, Cytokine Release Syndrome | 07/21 | 07/21 | | |
| Not yet recruiting | N/A | 100 | NA | Hydrocortisone-Lidocaine, Splint | National University Hospital, Singapore | De Quervain Syndrome | 02/24 | 02/24 | | |
