| Victoza (liraglutide) / Novo Nordisk |
ChiCTR-TRC-14004464: Efficacy of liraglutide QD vs. sitagliptin QD vs. insulin glargine on liver fat when combined with metformin in T2DM subjects with NAFLD |
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| Completed | N/A | 150 | | Liraglutide ;Sitagliptin ;Insulin glargine | The 3rd Affiliated Hospital of Sun-Yat Sen University; The 3rd Affiliated Hospital of Sun-Yat Sen University, Novo Nordisk | Type 2 Diabetes Mellitus Complicated With Non-alcoholic Fatty Liver Disease | | | | |
ChiCTR1800019864: Efficacy of dapagliflozin versus liraglutide in overweight and obese patients with inadequately controlled type 2 diabetes with insulin therapy |
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| Not yet recruiting | N/A | 80 | | Dapagliflozin ;Liraglutide | Tianjin Medical University Metabolic Diseases Hospital; Level of the institution：, Self-raised funds | diabetes | | | | |
ChiCTR1900024384: Effect of combination of liraglutide and metformin on body weight in patients with polycystic ovary syndrome: an observational study |
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| Recruiting | N/A | 102 | | liraglutide 0.6mg once daily and metformin 0.85g twice a day. And dinae-35 was prescribed that taking one pill per day for 21 days, and then stopping for 7days in every menstrual cycle. | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, self-supporting | Polycystic ovarian syndrome | | | | |
| Active, not recruiting | N/A | 120 | RoW | Metformin, Liraglutide, empagliflozin, Vildagliptin | Alexandria University, Eva Pharma | Fatty Liver, Nonalcoholic, Diabetes Mellitus, Type 2 | 09/21 | 09/22 | | |
ChiCTR2100046386: The effect of liraglutide on the level of microvesicles in type 2 diabetes patients with vascular complications |
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| Recruiting | N/A | | | Liraglutide treatment ;Use non-GLP-1RA and non-DPP-4 inhibitors of hypoglycemic drugs | Tianjin Medical University Zhu Xianyi Memorial Hospital; Tianjin Medical University Zhu Xianyi Memorial Hospital, Financial allocation and self-financed | Type 2 Diabetes Mellitus | | | | |
ChiCTR2100049645: Effects of liraglutide combined with insulin degludec or intermittent fasting in type 2 diabetes mellitus and related mechanisms |
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| Recruiting | N/A | 150 | | Liraglutide was combined with insulin deglume once daily ;Basal-prandial insulin ;5+2 light fasting ;Liraglutide injected subcutaneously once daily ;Oral metformin | Baoding First Central Hospital; Baoding First Central Hospital, none | Diabetes | | | | |
| Active, not recruiting | N/A | 80 | Europe | Liraglutide 6 MG/ML [Victoza], Placebos | Turku University Hospital | Gestational Diabetes | 09/24 | 12/27 | | |
ESCADA study, ChiCTR2000036600: Efficacy, cardiovascular benefits and safety of second-line anti-diabetic drugs in patients with type 2 diabetes: a real world based pragmatic clinical trial |
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| Not yet recruiting | N/A | 2000 | | glimepiride ;sitagliptin ;liraglutide ;dapaglifozin | Shanghai Sixth People's Hospital; Shanghai Sixth People's Hospital, A three-year action plan to promote clinical skills and clinical innovation in municipal hospitals | diabetes | | | | |
ChiCTR2000037090: Effect of short-term intensive metabolic therapy on cardiac structure and function in obese patients with type 2 diabetes or prediabetes |
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| Recruiting | N/A | 100 | | Low-calorie diet ;Liraglutide ;Bariatric surgery | Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University; Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Shenkang Hospital Development Centre | Obesity and type 2 diabetes or prediabetes | | | | |
ChiCTR2100052896: Randomized, double-blind, placebo-controlled clinical study on efficacy and safety of orlistat in treatment of overweight or obese type 2 diabetic patients who have poor effect of liraglutide on weight loss |
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| Recruiting | N/A | 60 | | Orlistat 0.12g (1 capsule) with meals or within one hour after meals, 3 times a day for 12 weeks ;Placebo | Shanghai Tongren Hospital; Shanghai Tongren Hospital, Self-funded | Type 2 diabetes mellitus with overweight or obese | | | | |
NCT04137328: Clinical Study on the Improvement of Diabetic Neuropathic Pain by Liraglutide |
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| Not yet recruiting | N/A | 60 | NA | Liraglutide, GLP-1RA, insulin | Fudan University | Diabetic Neuropathic Pain | 11/22 | 11/22 | | |
NCT05268627: Endoscopic Ultrasound Guided Gastric Botulinum Toxin Injections Versus Glucagon Like Peptide 1 Receptor Agonist in Weight Loss |
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| Recruiting | N/A | 38 | RoW | Liraglutide, Endoscopic ultrasound | Mansoura University | Obesity | 01/23 | 01/23 | | |
NCT02244164: Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments. |
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| Terminated | N/A | 5 | Europe | Incretinomimetics, - exenatide (Byetta®), - liraglutide (Victoza®), - lixisenatide (Lyxumia®), - exenatide extended-release (Bydureon®)., DPP-4 inhibitors, - sitagliptine (Januvia®), - vildagliptine (Galvus®), - saxagliptine (Onglyza®), - linagliptine (Trajenta®). | Erasme University Hospital | Type 2 Diabetes, Incretinomimetics, Pancreas | 02/23 | 02/23 | | |
NCT04990024: The Effect of Different Diets on Arterial Stiffness in Obese Patients on Liraglutide |
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| Recruiting | N/A | 150 | RoW | Dietary Intervention Med Diet, Dietary Intervention HP/LC Diet, Dietary Intervention LF Diet | American University of Beirut Medical Center | Obesity, Weight Loss | 06/23 | 06/23 | | |
ChiCTR2100042689: Study on the changes of brain function in obese patients using liraglutide based on multimodal functional magnetic resonance imaging |
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| Recruiting | N/A | 90 | | Liralgutide ;Nil | Jinling Hospital; Jinling Hospital, self-supporting | Obesity | | | | |
ChiCTR2200065628: The effects and mechanism of treatment with liraglutide on depression in patients with obesity |
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| Recruiting | N/A | 90 | | liraglutide | North District, The Municipal Hospital of Suzhou, Suzhou, China; North District, The Municipal Hospital of Suzhou, Suzhou, China, Natural Science Foundation of Jiangsu Province(BK20200211), Health professionals Foundation of Suzhou, Jiangsu Province (GSWS2021045) | Obesity | | | | |
ChiCTR2000035091: Intervention study of liraglutide in type 2 diabetes mellitus with nonalcoholic fats |
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| Recruiting | N/A | 400 | | Treatment with liraglutide ;placebo ;Human umbilical cord mesenchymal stem cells ;liraglutide+HUCMs | The 900th Hospital of the Joint Logistics Team; The 900th Hospital of the Joint Logistics Team, the Fujian Science and Technology Project | diabetes | | | | |
| Completed | N/A | 239990 | Europe | Canagliflozin, DPP4 inhibitor, Liraglutide, Saxagliptin, 2nd generation Sulfonylurea | AstraZeneca | Type 2 Diabetes Mellitus | 08/23 | 08/23 | | |
| Active, not recruiting | N/A | 150 | RoW | Metformin, Glucophage, Gliclazide, Diamicron, Diamicron MR, Sitagliptin, Januvia, Liraglutide, Victoza, Pioglitazone, Actos, Dapagliflozin, Forxiga, Farxiga, human insulin, novorapid, glargine | Weill Cornell Medical College in Qatar, Hamad Medical Corporation, Sidra Medical and Research Center, University of Hull | Diabetes Mellitus Type 2 | 10/23 | 10/24 | | |
LAMP, NCT03948347: Liraglutide in Acute Minor Ischemic Stroke or High-risk Transient Ischemic Attack Patients With Type 2 Diabetes Mellitus |
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| Recruiting | N/A | 1708 | RoW | Liraglutide, Victoza | First Affiliated Hospital of Jinan University | Ischemic Stroke, Transient Ischemic Attack, Type 2 Diabetes Mellitus | 12/23 | 06/24 | | |
| Completed | N/A | 60 | RoW | Liraglutide / Semaglutide, GLP1RA alone, Dapagliflozin, SGLT2i alone, Liraglutide or Semaglutide / Dapagliflozin, Combination of GLP1RA and SGLT2i, Liraglutide or Semaglutide / Dapagliflozin plus intensive weight loss nutrition, Combination of GLP1RA, SGLT2i and intensive weight loss nutrition, Usual care | Dasman Diabetes Institute | Type 1 Diabetes | 01/24 | 01/24 | | |
| Recruiting | N/A | 270000 | US | SU, DPP4, SGLT2i, GLP-1RA, SGLT2i or GLP-1RA, Linagliptin (DPP4), Exenatide (GLP-1RA), Liraglutide (GLP-1RA), Empagliflozin (SGLT2i), Glimepiride (SU), Glipizide (SU), Glimepiride (SU) or Glipizide (SU), SU or DPP4 (excluding saxagliptin and alogliptin), Exenatide (GLP-1RA) or Liraglutide (GLP-1RA) | Kaiser Permanente, Geisinger Clinic, Henry Ford Health System, HealthPartners Institute, Patient-Centered Outcomes Research Institute | Type 2 Diabetes Mellitus, Cardiovascular Diseases | 06/24 | 08/25 | | |
GOAL-AF, NCT05221229: Outcome of Overweight AF Patients Following Ablation With a Potential Weight Loss Medication ( ) |
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| Recruiting | N/A | 30 | Europe | Liraglutide plus upstream risk factors modification advice and consultation | University Hospital Birmingham, University of Birmingham | Atrial Fibrillation, Recurrence, Overweight and Obesity, Liraglutide | 09/24 | 03/25 | | |
ChiCTR2200064261: Effect of liraglutide combined with metformin on IVF/ICSI clinical pregnancy rates in obese women with PCOS: study protocol for a prospective, double-blind, single-center randomized controlled trial |
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| Not yet recruiting | N/A | 798 | | liraglutide combined with metformin | Taizhou People’s Hospital; Taizhou People’s Hospital, Funded by department research projects | polycystic ovary syndrome | | | | |
ChiCTR2300068435: Effect of GLP-1RA liraglutide on bone metabolic markers in newly diagnosed overweight type 2 diabetes |
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| Not yet recruiting | N/A | 60 | | GLP-1RA liraglutide + metformin + dagliflozin ;metformin + dagliflozin | Taixing People's Hospital; Taixing People's Hospital, research fund by ourselves | Type 2 diabetes | | | | |
NCT05705388: POSE2.0 With GLP-1 Agonist for Obesity Management |
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| Recruiting | N/A | 50 | RoW | POSE2.0 Endoscopic Gastric Remodeling, Liraglutide injection | Emirates Health Services (EHS) | Obesity | 01/25 | 01/26 | | |
NCT05779644: Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus |
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| Recruiting | N/A | 300 | RoW | Liraglutide, Semaglutide, Metformin | RenJi Hospital | Metformin, Obesity, Abdominal, Diabetes Mellitus, Type 2, Abdominal Fat, Non-Alcoholic Fatty Liver Disease, Metabolism Disorder, Glucose, Metabolism Disorder, Lipid | 02/25 | 02/25 | | |
LIGHT-MCI, NCT05313529: Effects of Liraglutide, Empagliflozin and Linagliptin on the Cognitive Function in T2DM Patients With Mild Cognitive Impairment: a Multicenter, Randomized, Parallel Controlled Clinical Trial |
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| Recruiting | N/A | 324 | RoW | Liraglutide, metformin, Empagliflozin, Linagliptin | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Wuxi People's Hospital, Nanjing First Hospital, Nanjing Medical University, The Affiliated Jiangning Hospital of Nanjing Medical University, Changzhou No.2 People's Hospital | Type 2 Diabetes Mellitus, Mild Cognitive Impairment | 12/26 | 12/27 | | |
