| methylprednisolone oral / Generic mfg. |
ACTRN12605000657628: A Multi-Centre, Open label Study to Investigate the Recovery of Interferon-b Efficacy in Relapsing-Remitting Multiple Sclerosis Patients with Neutralising IFN-b Antibodies and Reduced Bioavailability. |
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| Recruiting | 4 | 20 | | | Biogen Idec Australia Pty Ltd, Biogen Idec Australia Pty Ltd | Relapsing-remitting Multiple Sclerosis | | | | |
2007-006252-19: Einfluss von peroraler Methylprednisolon-Gabe auf die postoperative Morbidität nach operativer Weisheitszahnenfernung im Unterkiefer.(Influence of peroral Methylprednisolone administration on the postsurgical morbidity after surgical removal of lower third molars.) |
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| Ongoing | 4 | 16 | Europe | Methylprednisolon, MP, | Univ.-Prof. DDr. Norbert Jakse, Universitätszahnklinik Graz, Dep. f. Orale Chirurgie u. Röntgenologi | To be investigated is the anti-inflammatory and anti-oedematous effect of methylprednisolone on the postoperative sequelae after surgical removal of lower third molars.16 healthy patients will undergo surgical removal of bilateral symmetrically placed lower third molars. Each patient will be administered 1mg methylprednisolone per kg weight 1 hour prior to the surgery on one side, and a placebo containing lactose an the other side on a random basis. | | | | |
ChiCTR-IIR-16008994: Safety and efficacy analysis of two conventional dosage regimens Methylprednisone for initial treatment of primary immune thrombocytopenia：A multicenter randomized controlled clinical trial |
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| Not yet recruiting | 4 | 300 | | Oral methylprednisolone for 2 weeks, the initial dosage is 0.8mg/kg/d, than reduces to 0.4mg/kg/d for 1 week, than to 0.2mg/kg/d for 1 week, than stop. ;Oral methylprednisolone for 1 month, the initial dosage is 0.8mg/kg/d，than reduces to 0.4mg/kg/d for 1 month, than to 0.1mg/kg/d for 2 week, than stop. | Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College; Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College, Provide their own | Primary immune thrombocytopenia | | | | |
| Terminated | 4 | 3 | US | Glucocorticoids, Dexamethasone, Methylprednisolone, Saline | Vanderbilt University Medical Center | Elbow Fracture | 03/23 | 03/23 | | |
NCT05097976: Medrol Dosepak for Outpatient Total Knee Arthroplasty |
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| Recruiting | 4 | 420 | US | Methylprednisolone, medrol dosepak, Placebo | Rush University Medical Center | Total Knee Arthroplasty | 12/24 | 12/25 | | |
NCT03898154: Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures |
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| Recruiting | 4 | 200 | US | Dexamethasone, Methylprednisolone | C. Liam Dwyer | Distal Radius Fracture | 12/24 | 12/24 | | |
| Recruiting | 4 | 56 | Europe | Methylprednisolone, Placebo, natalizumab (NTZ), fingolimob (FTY) | University Hospital, Clermont-Ferrand | Multiple Sclerosis | 06/24 | 07/24 | | |
| Recruiting | 4 | 200 | US | Methylprednisolone, Standard of Care | Emory University | Knee Arthritis | 07/24 | 07/24 | | |
| Recruiting | 4 | 100 | US | Statin, HMG-coA reductase Inhibitor, methylprednisolone, medrol, dexamethasone, decadron, Placebo | Northwestern University | Sudden Sensorineural Hearing Loss | 10/24 | 12/24 | | |
| Not yet recruiting | 4 | 90 | RoW | Oral Glucocorticoids, methylprednisolone, Oral placebo | Beijing Tongren Hospital | Chronic Rhinosinusitis With Nasal Polyps, Glucocorticoids | 12/24 | 11/25 | | |
NCT03661645: Post-operative Methylprednisolone Taper Course for Orthopedic Surgery |
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| Enrolling by invitation | 4 | 1000 | US | 10 mg IV dexamethasone & 6 day oral methylprednisolone taper, Medrol, Depo-Medrol, Solu-Medrol, A-Methapred, Decadron, Dexasone, Diodex, Hexadrol, Maxidex, 10 mg IV dexamethasone | Emory University | Orthopedic Surgeries | 01/25 | 01/25 | | |
NCT05514015: Clinical Study of Rituximab Combined With Corticosteroids or Rituximab Monotherapy in the Treatment of Primary Membranous Nephropathy |
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| Recruiting | 4 | 78 | RoW | rituximab combined with corticosteroids, Intervention arm, rituximab, Control arm | First Affiliated Hospital, Sun Yat-Sen University | Primary Membranous Nephropathy | 09/26 | 12/26 | | |
ChiCTR2300071247: Short-term vs Long-term Systemic Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease with Different Clinical Phenotypes |
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| Not yet recruiting | 4 | 240 | | Injection of methylprednisolone 40mg*1-5d ;Injection of methylprednisolone 40mg*1-5d; Oral methylprednisolone 40mg*6-14d ;Injection of methylprednisolone 40mg*1-5d ;Injection of methylprednisolone 40mg*1-5d; Oral methylprednisolone 40mg*6-14d | Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Ji'nan University; The First Affiliated Hospital of Ji'nan University (Guangzhou Overseas Chinese Hospital), The First Affiliated Hospital of Ji'nan University | chronic obstructive pulmonary disease | | | | |
| Ongoing | 3 | 262 | Europe | Prednisolone (Tablet 1mg), Prednisolone (Soluble Tablet 5mg), Prednisolone (Oral Solution 10mg/ml), Human Normal Immunoglobulin (IVIg 100mg/ml), Aspirin (Dispersible Tablet 75mg), Aspirin (Tablets 300mg), Prednisolone (Tablet 5mg), Prednisolone (Tablet 10mg), Prednisolone (Tablet 2.5mg), Prednisolone (Tablet 20mg), Prednisolone (Tablet 25mg), Prednisolone (Tablet 30mg), Methylprednisolone (500mg), Methylprednisolone (1000mg), Human Normal Immunoglobulin (IVIg 50mg/ml), Aspirin (Tablet 75mg), Methylprednisolone (40mg), Methylprednisolone (125mg), Methylprednisolone (2g), B01AC06, Tablet, Soluble tablet, Oral solution, Solution for injection/infusion, Dispersible tablet, Powder and solvent for solution for injection/infusion, Powder for injection, Asaflow (80mg), Aspirine (100mg), Aspegic 100mg, Cardioaspirine (100mg), Solu-Medrol S.A.B. (40mg), Octagam (50 mg/ml) solution for infusion, Octagam 10% solution for infusion, Privigen 100 mg/ml solution for infusion, Iqymune (100mg/mL), Okrido 6mg/ml drank | MRC CTU at UCL, Medical Research Council Clinical Trials Unit at University College London, UNIVERSITY COLLEGE LONDON, MRC Clinical Trials Unit at University College London (UCL), Innovative Medicines Initiative 2 Joint Undertaking, Innovative Medicines Initiative 2, Innovative Medicine Initiative 2 Joint Undertaking | Kawasaki Disease, Kawasaki Disease, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2022-000712-59: Severe erythema multiforme: A randomized controlled trial comparing a short systemic corticosteroids regimen to placebo in the acute established phase Erythème polymorphe grave : étude contrôlée randomisée comparant une corti-cothérapie systémique courte à un placebo dans la phase aigüe constituée |
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| Ongoing | 3 | 96 | Europe | Prednisone 20 mg, METHYLPREDNISOLONE, Tablet, Powder for injection, PREDNISONE ARROW®20 mg, METHYLPREDNISOLONE VIATRIS 120 mg | Assistance Publique - Hôpitaux Paris (Direction de la Recherche Clinique et de l’Innovation), Health ministry | Erythema multiforme (EM) in its severe form managed at the hospital L’érythème polymorphe (EP) dans sa forme sévère pris en charge à l'hôpital, Patients suffering from Erythema multiforme (EM) in its severe form L’érythème polymorphe (EP) dans sa forme sévère pris en charge à l'hôpital, Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
| Active, not recruiting | 3 | 600 | Europe | Rituximab, Ruxience, Rixathon® or other biosimilar rituximab, Ocrelizumab, Ocrevus, Fexofenadine, Paracetamol, Methylprednisolone | Rigshospitalet, Denmark, Odense University Hospital, Aarhus University Hospital, Aalborg University Hospital, Herlev Hospital, Hillerod Hospital, Denmark, Kolding Sygehus, Gødstrup Hospital, Hvidovre University Hospital, Hospital of South West Jutland, Esbjerg, Denmark, GCP unit, Copenhagen University Hospital, GCP-unit at Aarhus University Hospital, Aarhus, Denmark, Hospital of Southern Jutland, Sønderborg, Denmark, Hospital of Central Denmark Region, Viborg, Denmark, Danske Regioner, Hospital of Southern Jutland, Aabenraa, Denmark, Sanquin Research & Blood Bank Divisions | Relapsing Remitting Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis | 05/26 | 05/28 | | |
NCT05003596: Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand |
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| Not yet recruiting | 2/3 | 60 | US | Methylprednisolone Tablet, Solu-Medrol Dosepak, Standard Mobilization Treatment, buddy taping, finger splint, tylenol, narcotics | Robert Wood Johnson Barnabas Health, Brielle Orthopedics, University Orthopedics Associates | Hand Injuries, Finger Injuries | 08/22 | 09/23 | | |
2020-004534-38: A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment |
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| Not yet recruiting | 2 | 300 | Europe | DUR-928 30mg, DUR-928 90mg, Methylprednisolone, DUR-928, NDC 59762-0051-1, Concentrate for solution for infusion, Capsule, hard + tablet, Methylprednisolone | DURECT Corporation, DURECT Corporation | Alcoholic hepatitis, Damage to your liver due to drinking too much alcohol over a long period of time, Diseases [C] - Nutritional and Metabolic Diseases [C18] | | | | |
| Not yet recruiting | 2 | 79 | RoW | Methylone, Placebo | Transcend Therapeutics | Post Traumatic Stress Disorder | 12/25 | 12/25 | | |
| Enrolling by invitation | 2 | 150 | Europe | Methylone | Transcend Therapeutics | Post Traumatic Stress Disorder | 05/27 | 05/27 | | |
NCT04918953: Factors Influencing the Prognosis of Olfactory Dysfunction After Upper Sensation |
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| Not yet recruiting | 2 | 90 | RoW | methylprednisolone, Olfactory training, budesonide atomization suspension | Second Affiliated Hospital, School of Medicine, Zhejiang University | Outcome | 12/25 | 12/26 | | |
| Recruiting | 1/2 | 79 | Europe | Methylone, Placebo | Transcend Therapeutics | Post Traumatic Stress Disorder | 12/24 | 12/24 | | |
ChiCTR1800019050: The effect of single periocular injection of methylprednisolone and drainage of suprachoroidal fluid in the treatment of rhegmatogenous retinal detachment combined with choroidal detachment |
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| Completed | 1 | 70 | | periocular injection of methylprednisolone ;oral prednisolone | The Eye Hospital of Wenzhou Medical University; The Eye Hospital of Wenzhou Medical University, Supporting Funds of the The Eye Hospital of Wenzhou Medical University | rhegmatogenous retinal detachment combined with choroidal detachment | | | | |
| Active, not recruiting | 1 | 17 | Europe | Methylone, 3,4-methylenedioxy-N-methylcathinone, MDMC, 3,4-methylenedioxymethamphetamine, MDMA, Ecstasy, Placebo, Non active treatment | Germans Trias i Pujol Hospital, Fundació Recerca Institut Germans Trias i Pujol, Istituto Superiore di Sanità | Substance Use, Healthy Subjects | 07/22 | 09/22 | | |
| Terminated | 1 | 30 | US | Dexamethasone, Methylprednisolone, Standard of Care | Indiana Hand to Shoulder Center | Fractures, Bone, Fractures, Closed, Radius Fracture Distal | 05/23 | 05/23 | | |
NCT06209606: Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma |
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| Not yet recruiting | 1 | 30 | NA | Ruxolitinib Oral Tablet [Jakafi], Ruxolitinib, Jakafi, Lenalidomide, Revlimid, Methylprednisolone, Depo-Medrol, Solu-Medrol, Methyl Prednisolonate | Oncotherapeutics, Incyte Corporation | Multiple Myeloma | 05/26 | 02/29 | | |
| Not yet recruiting | 1 | 30 | NA | Selinexor, Ruxolitinib, Methylprednisolone | Oncotherapeutics | Multiple Myeloma in Relapse, Multiple Myeloma, Refractory | 04/27 | 05/27 | | |
NCT06303648: A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects |
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| Recruiting | 1 | 24 | RoW | Methylone | Transcend Therapeutics | Post Traumatic Stress Disorder | 05/24 | 05/24 | | |
I-RUX-15-04, NCT03110822: A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients |
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| Recruiting | 1 | 134 | US | Ruxolitinib Oral Tablet [Jakafi], Ruxolitinib, Jakavi, Lenalidomide, Revlimid, Methylprednisolone, Depo-Medrol, Solu-Medrol, Methyl Prednisolonate | Oncotherapeutics, Incyte Corporation | Multiple Myeloma | 09/24 | 02/27 | | |
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NCT06468007: Comparative Effects of Methylprednisolone and Prednisolone on the Risk of Acute Decompensated Heart Failure - An Emulated Target Trial |
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| Completed | N/A | 12000 | NA | Methylprednisolone Tablet, Prednisolone Tablet | Diakonhjemmet Hospital | Heart Failure; With Decompensation | 08/17 | 12/17 | | |
ChiCTR-INR-17011495: Canceled by the investigator The efficacy and safety of metformin hydrochloride combined with atorvastatin in the treatment of primary mild to moderate systemic sy |
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| Recruiting | N/A | 90 | | The level of SELSNA-SLEDAI was evaluated at week 4, week 12 and week 24, the BILAG table, the SLE lesion index, and the SLE damage index were measured at 4 weeks, 12 weeks and 24 weeks. The levels of Th17, Treg and Th17 / Treg were measured. ;Leflunomide tablets 10m, 1 times / day, orally. The SELSNA-SLEDAI score table, BILAG worksheet, SLE damage index score were assessed at week 4, week 12 and week 24, and serum Th17, Treg and Th17 / Treg ratios were measured. ;0 weeks to give prednisone acetate tablets 0.5-1mg / kg.d (or patients can choose to take the same dose of methylprednisolone tablets), 4 weeks after the beginning of the dose by 2 weeks to reduce the regular dose of 10% Reduction to prednisone acetate tablets 10mg / day to maintain. ;All patients without contraindications plus hydroxychloroquine tablets 0.2,2 / day, orally; and according to the condition plus calcium (800-1200mg / day), vitamin D (200-800IU / day) and other treatment. | The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology; The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Self-raised | Primary mild to moderate systemic systemic lupus erythematosus | | | | |
| Completed | N/A | 56 | | Methylprednisolone 16mg Tablets (Zhejiang Xianju) ;Methylprednisolone 16mg Tablets (Zhejiang Xianju) ;Methylprednisolone 16mg Tablets (Pfizer) ;Methylprednisolone 16mg Tablets (Pfizer) | People's Hospital of Deyang City; People's Hospital of Deyang City, Xianju Pharmaceutical (Zhejiang) Co., Ltd | symptomatic treatment with glucocorticoid | | | | |
NCT05990894: Steroid for Treatment of Acute/Subacute Severe Cerebral Venous Thrombosis. |
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| Completed | N/A | 248 | RoW | Methylprednisolone | Xuanwu Hospital, Beijing | Cerebral Venous Thrombosis | 12/21 | 12/21 | | |
NCT06044558: Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics |
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| Completed | N/A | 507 | RoW | Combined with voriconazole, tacrolimus, methylprednisolone sodium succinate, mycophenolate sodium, Combined with caspofungin, Tacrolimus-alone treatment | LI YAN | Kidney Transplant Patients | 01/23 | 06/23 | | |
NCT03856229: Short-term Steroid Therapy in Patients With P. Jirovecii Pneumonia Due to HIV / AIDS |
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| Enrolling by invitation | N/A | 196 | RoW | Conventional steroid regimen, CoSt, Shortened steroid regimen, SSt | Centro de Investigación en. Enfermedades Infecciosas, Mexico | Pneumocystis, HIV/AIDS, Steroid | 10/24 | 10/25 | | |
NCT06198894: Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative Symptoms |
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| Recruiting | N/A | 96 | RoW | steroid-eluting sinus stent implant, BISORB bioabsorbable steroid-eluting sinus stent, Systemic glucocorticoids, Medrol, saline irrigations, 0.9% sodium chloride solution, Placebo, Systemic glucocorticoid placebo, sham procedure, In-office bilateral sham procedure of stent placement | Zheng Liu | Chronic Sinusitis | 01/26 | 04/26 | | |
NCT05842681: Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis |
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| Not yet recruiting | N/A | 30 | RoW | Azithromycin, azithromycin 500 mg oral tablet, Methylprednisolone, methylprednisolone 500 mg | Assiut University | Idiopathic Pulmonary Fibrosis | 03/24 | 06/24 | | |
ChiCTR2300075076: The effect of combined low-dose methylprednisolone on neurological function and hemodynamics in patients with acute cerebral infarction combined with rheumatoid arthriti |
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| Not yet recruiting | N/A | 100 | | oral aspirin tablets (100mg once a day), Clopidogrel (75mg once a day), Atorvastatin calcium tablets (20mg once a day); ;Oral administration of methylprednisolone tablets (4mg once per day) on the basis of the control group | Xi'an Fifth Hospital; Xi'an Fifth Hospital, Scientific Research Project of Shaanxi Administration of Traditional Chinese Medicine | Cerebrovascular disease | | | | |
ChiCTR1900021199: Mycophenolate Plus Concomitant Steroids versus Orbital Radiotherapy Plus Concomitant Steroids in the treatment of intractable Graves’ ophthalmopathy: a randomised, controlled multicentre trial |
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| Recruiting | N/A | 96 | | oral steroid combined with mycophenolate, Oral methylprednisolone (0.4 mg / kg, for 4 weeks, gradually reduced to a maintenance dose of 4 mg qd) and oral mycophenolate mofetil (500 mg bid) for 24 weeks ;oral steroid combined with orbital radiotherapy | Sun Yat-sen Memorial Hospital, Sun Yat-Sen University; Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University | Intractable Graves’ ophthalmopathy | | | | |
NCT05668910: Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA |
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| Recruiting | N/A | 360 | RoW | whole genomic methylation and fragmentation profile analysis of cfDNA | GeneCast Biotechnology Co., Ltd., The First Affiliated Hospital of Air Force Military Medical University (Xijing Hospital) | Gastric Cancer | 03/24 | 03/24 | | |