Not yet recruiting

N/A

25

 

Peninsula Health, Frankston Hospital, The Angior Family Foundation

Sleep in Critically ill patients, sleep disruption.

 

 

Completed

N/A

40

 

dexmedetomidine

Third affiliated hospital of Anhui Medical University; Third affiliated hospital of Anhui Medical University, Departemnt funding

tumors of lung and oesophagus

 

 

Recruiting

N/A

90

 

Dexmedetomidine ;cervical plexus nerve block ;normal saline

The Third Affiliated Hospital of Sun Yat-sen University; Level of the institution：, self-raised funds

thyroid disease

 

 

Recruiting

N/A

150

 

sevoflurane only ;sevoflurane plus propofol ;sevoflurane plus dexmedetomidine

Shanghai Tongji Hospital; Shanghai Tongji Hospital, National Natural Science Foundation 81600934, Natural Science Foundation of Shanghai, China (16ZR1432200); Science Lead Supporting project of Shanghai, China (16411967700)

Postoperative cognitve dysfunction

 

 

Not yet recruiting

N/A

60

 

dexmedetomidine

Department of Anesthesiology, Tongji Hospital, Tongji University; Tongji Hospital Affiliated to Tongji University, Shanghai?Science?and?Technology?Committee

cerebral infarction

 

 

Not yet recruiting

N/A

30

 

Dexmedetomidine

The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital; The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, None

Catheter-related bladder discomfort

 

 

Completed

N/A

40

 

none ;add some dose of dexmedetomidine to local anesthetics

The Second Affiliated Hospital, Harbin Medical University; The Second Affiliated Hospital, Harbin Medical University, Department of anesthesiology, Second affiliated Hospital, Harbin Medical University

renal diseases

 

 

Completed

N/A

105

 

caudal levobupivacaine ;levobupivacaine and 1ug/kg dexmedetomidine ;levobupivacaine and 1ug/kg dexmedetomidine

Guangzhou Women and Childrens Medical Center; Guangzhou women and chilren's medical center, self-financing

inguinal hernia andhydrocele in children

 

 

Completed

N/A

210

 

0.25%levobupivacaine ;0.20%levobupivacaine ;0.20%levobupivacaine and 2ug/kg dexmedetomidine

Guangzhou Women andChildrens Medical Center; guangzhou women and children's medical center, self-financing

inguinal hernia andhydrocele in children

 

 

Completed

N/A

100

 

dexmedetomidine ;midazolam

Department of Anesthesiology, First Hospital of Soochow University; The First Affiliated Hospital of Soochow University, self-financing

Anesthesia of orthopedics

 

 

Completed

N/A

200

 

the patients of control group will be administrated saline the same way as the dexmedetomidine ;Patients of dexmedetomidine group will be administrated initial dose of dexmedetomidine (0.5ug /kg) pump over 10 min 30 minutes before induction of anesthesia, subsequently receive 0.4 ug/kg-1/h dose until the surgery finished

Nanjing First Hospital affiliated to Nanjing Medical University; Nanjing First Hospital affiliated to Nanjing Medical University, self-funding

adult acute kidney imparement after cardiopulmonarybypass

 

 

Completed

N/A

40

 

drug

The Third Xiangya Hospital Of Central South University; The Third Xiangya Hospital Of Central South University, the National Scientific Foundation of China (No. 81373476, 81302851, 81301924), the National Science and Technology Major Projects for “Major New Drugs Innovation and Development” (2012ZX09303014-001

Surgical patients

 

 

Completed

N/A

518043

NA

Dexmedetomidine

Xijing Hospital, The Affiliated Hospital of Qingdao University, First Hospital of China Medical University, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Sir Run Run Shaw Hospital

In-hospital Mortality

06/18

07/18

Completed

N/A

100

 

dexmedetomidine/sufentanil ;sufentanil

Shanghai Eye, Ear, Nose, and Throat Hospital, Fudan University; Level of the institution：, none

laryngectomy

 

 

Completed

N/A

75

 

0.5 ug/kg dexmedetomidine ;0.7 ug/kg dexmedetomidine ;0.03 ug/kg remifentanil

Shanghai Eye, Ear, Nose, and Throat Hospital, Fudan University; Shanghai Eye, Ear, Nose, and Throat Hospital, Fudan University, No

airway protection during emergence

 

 

Completed

N/A

250

 

NS ;0.5μg/kg Dexmedetomidine ;0.75μg/kg Dexmedetomidine ;1.0μg/kg Dexmedetomidine ;1.0μg/kg Dexmedetomidine

The First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Wenzhou Medical University, self-raise

renal stones

 

 

Completed

N/A

120

 

intravenously physiological saline 20mL ;lower dose (0.5ug kg-1) of dexmedetomidine ;Higher dose (1ug kg-1) of dexmedetomidine

Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, Self-financing

Cesarean Section

 

 

Not yet recruiting

N/A

70

 

Patients receiving dexmedetomidine 1 ug/kg for 10 min followed by 0.5 ug/kg.h until the end of the examination ;fentanyl methord 0.6 mg/kg i.v., plus 10~20mg if necessary

Department of Anesthesiology, the Second Hospital of Anhui Medical University; Department of Anesthesiology, the Second Hospital of Anhui Medical University, Scientific Support Programs for Clinical Research of the Second Affiliated Hospital of Anhui Medical University

anesthesia and analgesia

 

 

Not yet recruiting

N/A

120

 

Airway was maintained by LMA and sevoflurane and remifentanil was used ;Patients were intubated and sevoflurane and remifentanil was used ;Airway was maintained by LMA and propofol and remifentanil was used ;Patients were intubated and propofol and remifentanil was used ;Dexmedetomidine was spayed into both nostrils with MADgic atomizer 15min before induction ;Normal saline was spayed into both nostrils with MADgic atomizer 15min before induction

The Eye Ear Nose and Throat Hospital Affiliated to Fudan University; The Eye Ear Nose and Throat Hospital Affiliated to Fudan University, The Eye Ear Nose and Throat Hospital Affiliated to Fudan University

chronic sinusitis

 

 

Recruiting

N/A

40

 

Dexmedetomidine is intravenously administrated at a dose of 1.0ug/kg at 10 min intervals, then continuous infusion at 0.5 ug/kg/h for 20 min. ;Dexmedetomidine is intravenously administrated at a dose of 1.0ug/kg at 10 min intervals, then continuous infusion at 0.5 ug/kg/h for 20 min.

Department of Anesthesia, Obstetrics and Genecology Hospital, Fudan University; Level of the institution：, Department of Anesthesia, Obstetrics and Genecology Hospital, Fudan University

General Anesthesia

 

 

Completed

N/A

180

 

Normal saline is intravenously administrated before anesthesia induction ;Dexmedetomidine is intravenously administrated at a dose of 1.0μg/ kg at 10 min intervals before anesthesia induction, remifentanil maintenance at a dose of 0.3μg/kg·min ;Flurbiprofen axetil is intravenously administrated at a dose of 1.5mg/ kg before anesthesia induction, remifentanil maintenance at a dose of 0.3μg/kg.min ;Flurbiprofen axetil is intravenously administrated at a dose of 1.5mg/ kg before 15 minutes completion of surgery, remifentanil maintenance at a dose of 0.3μg·kg·min ;Dexmedetomidine is intravenously administrated at a dose of 1.0μg/ kg at 10 min intervals and Flurbiprofen axetil is intravenously administrated at a dose of 1.0mg/kg before anesthesia induction, remifentanil maintenance at a dose of 0.3μg·kg·min ;Dexmedetomidine is intravenously administrated at a dose of 1.0μg/ kg at 10 min intervals before anesthesia induction, and Flurbiprofen axetil is intravenously administrated at a dose of 1.5mg/ kg before 15 minutes completion of surgery, remifentanil maintenance at a dose of 0.3μg·kg·min

Fujian Provincial Hospital; None, Scientific research found of Fujian Provincial Hospital

Hyperalgesia

 

 

Recruiting

N/A

80

 

Dexmedetomidine ;0.9%NaCl

Third Affiliated Hospital, Sun Yat-sen University; Level of the institution：, self-financed

prostate cancer

 

 

Recruiting

N/A

75

 

infuse dexmedetomidine ;stimulate at the point of Bahui and Shuigou by electroacupuncture ;dexmedetomidine combined electroacupuncture

Anhui Provincial Hospital; None, self-raised

cardiac surgery

 

 

Recruiting

N/A

90

 

medication ;adminstrated ropivacaine ;adminstrated ropivacaine with dexmedetomidine

Tianjin Medical University General Hospital; Tianjin Medical University General Hospital, self support

Ischemic disease of lower extremity

 

 

Completed

N/A

80

 

dexmedetomidine plus remifentanil to controlled hypotension ;use remifentanil to controlled hypotension

Shanghai Eye, Ear, Nose, and Throat Hospital, Fudan University; Level of the institution：, None

tympanoplasty

 

 

Completed

N/A

75

 

intravenous anesthesia of proposal and remifentainl ;anesthesia of dexmedetomidine ;anesthesia of dexmedetomidine

Beijing Tiantan Hospital Affiliated to Capital Medical University; Level of the institution：, found of department

thoracic intraspinal tumor

 

 

Recruiting

N/A

120

 

dexmedetomidine 1ug/kg I.V. ;NS

The Third Affiliated Hospital, Sun Yat-sen University; The Third Affiliated Hospital, Sun Yat-sen University, None

Systemic inflammatory response syndrome (SIRS)

 

 

Not yet recruiting

N/A

2000

 

epidural dexmedetomidine ;epidural levobupivacaine and sufentanil

Department of Anesthesiology, Guangzhou Women andChildren Medical Center; Guangzhou Women and Children Medical Center, Departmental finance

nulliparous women in spontaneous labor or with spontaneous rupture of the membranes.

 

 

Completed

N/A

84

 

propofol for anesthesia maintenance, a loading dose of dexmedetomidine ;sevoflurane for anesthesia maintenance, a loading dose of dexmedetomidine ;propofol for anesthesia maintenance, volume-matched normal saline ;sevoflurane for anesthesia maintenance, volume-matched normal saline

Xuzhou Medical University; The Affiliated Hospital of Xuzhou Medical University, Department of Anesthesiology，the Affiliated Hospital of Xuzhou Medical University

Perioperative hemodynamics

 

 

Recruiting

N/A

20

 

dexmedetomidine vs dexmedetomidine plus yohimbine

the Third Xiangya Hospital of Central South University; the Third Xiangya Hospital of Central South University, National Natural Science Foundation of China

breast carcinoma

 

 

Recruiting

N/A

300

 

transverse abdominal plan block ;dexmedetomidine ;patient-controlled analgesia

The First Affiliated Hospital of Wannan Medical College; Level of the institution：, Self-raised fund

Gynecologic laparoscopy

 

 

Recruiting

N/A

200

 

Dexmedetomidine ;Transcutaneous electrical stimulation+Azasetron ;Dexmedetomidine+TENS+Azasetron ;Azasetron

An Hui Provincial Hospital; Anhui Provincial Hospital, Self-financing

postoperative nausea andvomiting

 

 

Recruiting

N/A

60

 

a TAP block with 20 ml of 0.375% ropivacaine ;a TAP block with 20 ml of 0.375% ropivacaine and 1 ug/kg dexmedetomidine

Wannan Medical College First Affiliated Hospital, Yijishan Hospital; Wannan Medical College First Affiliated Hospital, Yijishan Hospital, The three new key project (three new project-new technology, new treatment, new way) of Yijishan Hospital of Wannan Medical College

Gynecological laparoscopy

 

 

Recruiting

N/A

72

 

dexmedetomidine

the anesthesia department of Liaocheng People's hospital; Liaocheng People's Hospital, the graduate students scientific research funds

postoperation delirium

 

 

Recruiting

N/A

60

 

sufentanil ;sufentanil plus dexmedetomidine

Affiliated Hospital of Qingdao University; Affiliated Hospital of Qingdao University, No Funding

postoperative analgesia for patients undergoing abdominal hysterectomy

 

 

Recruiting

N/A

60

 

Dexmedetomidine ;Placebo

Anaesthesiology Department, Peking University First Hospital; Peking University First Hospital, Study Leader

intracranial tumor

 

 

Recruiting

N/A

90

 

lidocaine 1.5mg/kg was intravenous injected before anesthesia induction, lidocaine 2mg/kg.h was continuous infusion after intubation ;Dexmedetomidine 1ug/kg was intravenous injected before anesthesia induction, dexmedetomidine 0.4ug/kg.h was continuous infusion after intubation ;Equivalent saline was intravenous injected before anesthesia induction and continuous infusion after intubation

Department of Anesthesiology, West China Second Hospital of Sichuan University; West China Second Hospital of Sichuan University, NO

uterine fibroid

 

 

Recruiting

N/A

60

 

oral dexmedetomidine ;oral ketamine ;oral dexmedetomidine mixed with ketamine

Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University; Shanghai Children’s Medical Center, Science and Technology Development Fundation of Pudong New District (PKJ2015-Y02)

Tetralogy of Fallot

 

 

Not yet recruiting

N/A

30

 

receive dexmedetomidine sedation ;receive propofol sedation

the First Affiliated Hospital of Sun Yat-Sen University; the First Affiliated Hospital of Sun Yat-Sen University, self financing

unlimited

 

 

Recruiting

N/A

40

 

Perioperative use of dexmeditomidine ;Perioperative use of normal saline

Tianjin Medical University Cancer Institute and Hospital; Tianjin Medical University Cancer Institute and Hospital, The national key clinical specialist research fund

thoracic cancer

 

 

Not yet recruiting

N/A

40

 

ultrasound guided bilateral tranversus abdominis plane block with 0.9% saline ;ultrasound guided bilateral tranversus abdominis plane block with dexmedetomidine

The maternal and child hospital, fujian province; The maternal and child hospital, fujian province, The study project of hospital

hyperalgesia

 

 

Recruiting

N/A

88

 

epidural administration of1.0 μg/kg dexmedetomidine 5 ml ;Epidural administration of 2μg/ml fentanyl 5ml

department of Anesthesiology, Harbin Medical University Cancer Hospital, Ha Ping Road 150, Nan Gang Qu, Harbin, Hei Longjiang Province, China; Harbin Medical University Cancer Hospital, Translational medicine special fund medical research center project between China and Russia

postoperative gastrointestinal motility recovery

 

 

Recruiting

N/A

84

 

Dexmedetomidine and oxycodone ;Oxycodone

Shandong Cancer Hospital and Institute; Shandong Cancer Hospital and Institute, self-service

lung cancer

 

 

Recruiting

N/A

100

 

only PCIA for analgesia ;0.375% ropivacaine ;0.375% ropivacaine combined with fentanyl ;0.375% ropivacaine combined with Dexmedetomidine

Department of Anesthesiology, ChongQing Cancer Hospital; ChongQing Cancer Hospital, Self-raised

Abdominal surgery

 

 

Recruiting

N/A

60

 

mid-forearm nerves blocked with 0.75% ropivacaine ;mid-forearm nerves blocked with 0.75% ropivacaine mixed with dexmedetomidine ;mid-forearm nerves blocked with 0.75% ropivacaine and intravenous infusion of dexmedetomidine ;The supraclavicular brachial plexus was blocked with 1.5% lidocaine plus dexmedetomidine

The First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Wenzhou Medical University, self-financing

hand and wrist surgery

 

 

Recruiting

N/A

75

 

0.5ug/kg Dexmedetomidine iv.pump for 10min ;1.0ug/kg Dexmedetomidine iv.pump for 10min ;NS of same volume iv.pump for 10min

Shanghai Sixth People's Hospital; Level of the institution：, Hospital Level Research Fund

Effects of Dexmedetomidine on Rocuronium

 

 

Completed

N/A

194

RoW

Propofol injection, Pr, Dexmedetomidine injection, Dx, Dexmedetomidine and Propofol, DxPr

Anesthesia Research Group UA

Sedation Complication

02/18

12/19

Recruiting

N/A

66

 

Dexmedetomidine ;midazolam

Shanghai First People's Hospital; Shanghai First People's Hospital, National natural science foundation

Heart Disease

 

 

Not yet recruiting

N/A

160

 

Normal saline ;midazole 0.4mg/kg was given before operation ;ketamine 8mg/kg was given before operation ;Dexmedetomidine 3ug/kg was given before operation

Shanghai Ninth People's Hospital, School Of Medicine, Shanghai Jiaotong University; Shanghai Ninth People's Hospital, School Of Medicine, Shanghai Jiaotong University, self-financing

preoperative sedation

 

 

Recruiting

N/A

60

 

Before induction of anesthesia to 1ug/kg dexmedetomidine infusion ;30 minutes before the end of surgery in the B group to butorphanol 20ug/kg injection ;1ug/kg dexmedetomidine before induction of dexmedetomidine infusion, 30 minutes before the end of surgery to butorphanol 20ug/kg intravenous injection.

Affiliated Hospital of Xuzhou Medical University; Level of the institution：, raise independently

Urethral endoscopic surgery