Recruiting

1

136

 

Propofol Administer ;Midazolam Administer ;Fentanyl Administer ;Dexmedetomidine Administer

Beijing Tiantan Hospital, Capital Medical University ; Beijing Tiantan Hospital, Capital Medical University, Capital Medical University

Supratentorial Tumor

 

 

Completed

1

53

 

dexmedetomidine 1.0 ug/kg made up to 10 ml with NS, infused over a 15 minutes period using a syringe pump ;NS 10 ml, infused over a 15 minutes period using a syringe pump

The Second Affiliated Hospital of Anhui Medical University; The Second Affiliated Hospital of Anhui Medical University, Research Fund

elective gynecological operation

 

 

Completed

1

75

 

none ;add some dose of morphine to levobupivacaine ;add some dose of morphine to levobupivacaine

Second affiliated Hospital, Harbin Medical University; Level of the institution：, self-finance

Gastrointestinal diseases

 

 

Completed

1

130

 

dexmedetomidine versus control

Peking University, First Hospital; Peking University, First Hospital, self -raised fund

gynecologic laparoscopic surgery

 

 

Completed

1

546

 

1ug/kg Dexmedetomidine infusion in 10min ;1.5ug/kg Dexmedetomidine infusion in 10min ;2.0ug/kg Dexmedetomidine infusion in 10min

Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China; Level of the institution：, Zhejiang provincial natural science foundation; Zhejiang medical and health science and technology plan project

Pediatric Disease

 

 

Recruiting

1

60

 

dexmedetomidine analgesia ;fentanyl analgesia ;Physiological Saline

Shandong Provincial Cancer Hospital and Institute; Shandong Provincial Cancer Hospital and Institute, Nil

Gynecological Tumor

 

 

Not yet recruiting

1

30

 

intrathecal dexmedetomidine (DEX) 3 ug

The department of Anesthesiology of the Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, self-raised funds

shivering during Cesarean delivery under spinal anesthesia

 

 

Completed

1

90

 

Minocycline ;ulinastatin ;dexmedetomidine

Nanjing Hospital Affiliated to Nanjing Medical University(Nanjing First Hospital); Level of the institution：, Nanjing City medical science and Technology Development Fund

coronary heart disease

 

 

Recruiting

1

200

 

a loading dosage of dexmedetomidine (0.8 ug/Kg) was infused introvenously 10 min after induction and followed continously at 0.3 ug/Kg/h till 30 min before the ending of surgery ;same dosage of saline

The First Affiliated Hospital, College of Medicine, Zhejiang university; The First Affiliated Hospital, College of Medicine, Zhejiang University, Health Bureau of Zhejiang Province

postoperative delirium and cognitive dysfunction

 

 

Recruiting

1

80

 

Continuous intraoperative injection of dexmedetomidine during surgery ;Continuous pumping of saline during surgery

Stomatological Hospital of Wuhan University; Stomatological Hospital of Wuhan University, Self-pay

cleft palate

 

 

Recruiting

1

90

 

Pump remifentanil 0.5ug/kg (1min) 0.05ug/kg/min after surgery ;Pump remifentanil 0.5ug/kg (1min) 0.05ug/kg/min and dexmedetomidine 1ug/kg(10min)+0.5ug/kg/h after surgery ;Pump remifentanil 0.5ug/kg (1min) 0.05ug/kg/min and dexmedetomidine 1ug/kg(10min)+0.5ug/kg/h before induction

Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province; The Third Affiliated Hospital, Sun Yat-Sen University, Researcher's own expense

Chronic rhinosinusitis

 

 

Not yet recruiting

1

44

RoW

Dexmedetomidine injection, dexmedetomidine, Normal Saline

Dr. Ruth K.M. Pfau Civil Hospital, Karachi

Hypertension, Laparoscopic Cholecystectomy

03/21

03/21

Recruiting

1

45

RoW

Administration of Alprazolam , Gabapentin , Dexmedetomidine

Ehab Tarek Fahmy

Sedation for Patients Undergoing Peribulbar Block

06/21

08/21

Recruiting

1

120

 

Dexmedetomidine ;Normal saline

Cangzhou Central Hospital; Cangzhou Central Hospital, Hebei Province Medical Science Research Project

delirium

 

 

Completed

1

18

US

Dexmedetomidine buccal, Dexmedetomidine Intranasal

Children's Hospital Medical Center, Cincinnati

Heart Diseases

05/22

05/22

Completed

1

60

RoW

Dexmedetomidine 0.5 mic/kg/h, Lidocaine 0.5 mg/kg/h, Pregabalin 150 mg, Acetaminophen 1g, Ketorolac 30 mg, Celecoxib 200 mg, Fentanyl 1 mic/kg/hr, Morphine 0.1 mg/kg/hr

Cairo University

Anesthesia

08/22

10/22

Recruiting

1

350

RoW

Intra Operative Dexmedetomidine, intra operative precedex

Kasr El Aini Hospital

Postoperative Atrial Fibrillation

09/22

09/22

Completed

1

81

RoW

Ketamine- dexmedetomidine, Fentanyl- midazolam, Isoflurane

Cairo University

Anesthesia

09/22

09/22

Completed

1

330

RoW

Dexmedetomidine, Saline

RenJi Hospital

Dexmedetomidine, Liver Transplantation, Allograft Function, Survival

10/22

12/22

Not yet recruiting

1

60

 

ropivacaine 10mg +dexmedetomidine ;ropivacaine 8mg +dexmedetomidine

Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, Department finance

cesarean section under spinal anesthesia

 

 

Not yet recruiting

1

30

 

ropivacaine +dexmedetomidine

Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, Department finance

Cesarean section under spinal anesthesia

 

 

Not yet recruiting

1

140

 

No interventions ;Intravenous Infusion of Dexmedetomidine ;ultrasound-guided bilateral SCPB ;Combination of two interventions

The First Hospital of Quanzhou City, Fujian Province; The First Hospital of Quanzhou City, Fujian Province, East Branch of Quanzhou First Hospital, Fengze District, Quanzhou City, Fujian Province

Analgesia and quality of recovery after thyroid surgery

 

 

Not yet recruiting

1

60

 

Dexmedetomidine ;Normal saline

the First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Wenzhou Medical University, self-raised

valvular heart disease

 

 

Not yet recruiting

1

66

NA

Dexmedetomidine Hydrochloride, Midazolam

Sheikh Zayed Medical College

Agitation, Emergence

06/25

07/25

Not yet recruiting

1

90

 

Dexmedetomidine + Acupuncture ;Dexmedetomidine ;Acupuncture

The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, Research Fund

colorectal cancer

 

 

Recruiting

1

64

 

Dexmedetomidine ;Normal saline

Pengzhou People's Hospital; Pengzhou People's Hospital, self-raised

Lung cancer; Chronic obstructive pulmonary disease (COPD)

 

 

Completed

1

56

RoW

Dexmedetomidine, magnesium sulfate, Magnesium sulfate

mohamed, Azhar University

Hypotension

04/23

05/23

Recruiting

1

90

 

0.3% ropivacaine + 0.9% normal saline to make a 50mL solution ;0.3% ropivacaine + 0.25mg/kg esketamine + 0.9% normal saline to make a 50mL solution ;0.3% ropivacaine + 0.5ug/kg dexmedetomidine + 0.9% normal saline to make a 50mL solution

Guangzhou Medical University Affiliated Cancer Hospital; Guangzhou Medical University Affiliated Cancer Hospital, no

Gynecologic Oncology

 

 

Not yet recruiting

1

240

 

Propofol 1.5-2mg/kg, Sufentanil 0.5μg/kg and rocuronium 0.6 mg/kg were used for induction,Propofol 2-12mg/kg/h+ Remifentanil 2-4ug/kg/h for maintenance,Postoperative analgesia was administered with 4mg hydromorphone plus 8mg butorphanol ;Epidural puncture anesthesia was performed with 0.5% ropivacaine 5ml, followed by induction with propofol 1.5-2mg/kg and rocuronium 0.6 mg/kg. Maintenance was performed with 0.5% ropivacaine 8ml/h, propofol 2-12mg/kg/h, and dexmedetomidine 0.4μg/kg/h.Postoperative analgesia was administered with 100mg ketamine and 1.5mg/kg ketorolac ;Propofol 1.5-2mg/kg, rocuronium bromide 0.6 mg/kg and lidocaine 1mg/kg were used for induction.TAP was then performed using 0.25% ropivacaine 20ml.Maintenance was performed with propofol 2-12mg/kg/h, dexmedetomidine 0.3-0.6μg/kg/h, esketamine 0.2-0.5 mg/kg/h, and lidocaine 2mg/kg/h.Post-operative analgesia was administered with 100mg ketamine

The First Affiliated Hospital of University of South China; The First Affiliated Hospital of University of South China, State subsidy

Gynecological endoscopic surgery

 

 

Not yet recruiting

1

100

 

Ultrasound-guided supraclavicular brachial plexus block with 30 mL 0.33% ropivacaine ;Ultrasound-guided supraclavicular brachial plexus block with 30 mL 0.33% ropivacaine plus 25 μg dexmedetomidine ;Ultrasound-guided supraclavicular brachial plexus block with 30 mL 0.33% ropivacaine plus 50 μg dexmedetomidine ;Ultrasound-guided supraclavicular brachial plexus block with 30 mL 0.33% ropivacaine plus 75 μg dexmedetomidine ;Ultrasound-guided supraclavicular brachial plexus block with 30 mL 0.33% ropivacaine plus 100 μg dexmedetomidine

East China Normal University Wuhu Affiliated Hospital (The Second People's Hospital of Wuhu); East China Normal University Wuhu Affiliated Hospital (The Second People's Hospital of Wuhu), self-funded

upper extremity surgery

 

 

Not yet recruiting

1

60

NA

Dexmedetomidine injection, Precidex, Midazolam

Sheikh Zayed Medical College

Choosing Better Drug Option for Sedation in Pediatric Population Intraoperatively

07/23

10/23

Not yet recruiting

1

110

 

20 min before the end of surgery, 0.2 ug/kg dexmedetomidine was injected intravenously ;20 min before the end of surgery, 0.2 mg/kg remimazolam was injected intravenously

Tongji Hospital affiliated to Tongji Medical College, Huazhong University of Science and Technology; Tongji Hospital affiliated to Tongji Medical College, Huazhong University of Science and Technology, Self-funded

emergence agitation

 

 

Recruiting

1

70

RoW

Dexmedetomidine, Group (D 5):Patients will receive intrathecal 2 mL heavy bupivacaine 0. 5% together with dexmedetomidine 5 μg dexmedetomidine ., Group (D10):Patients will receive intrathecal 2 mL heavy bupivacaine 0. 5% together with dexmedetomidine 10 μg dexmedetomidine

Mansoura University

Transurethral Resection of Prostate

10/23

12/24

Recruiting

1

40

RoW

Midazolam, dexmedetomidine

Minia University

Renal Failure

11/23

12/23

Recruiting

1

780

RoW

S-ketamine, Dexmedetomidine, Normal saline

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Postoperative Delirium, Elderly Patients

12/23

02/24

Recruiting

1

50

RoW

Dexmedetomidine, precedex, normal saline, saline

Ain Shams University

Effect of Drug in CABAG Patients

12/23

12/23

Not yet recruiting

1

100

NA

Dexmedetomidine and Midazolam

Esraa Abdel Azez Soltan Mohamed Zayed

Emergence Delirium

09/24

10/24

Completed

1

56

RoW

Dexmedetomidine, DEX, Bupivacaine Hydrochloride, marcaine

Cairo University

Dexmedetomidine

07/24

08/24

Not yet recruiting

1

100

 

The patient received intraoperative infusion of propofol and dexmedetomidine ;The patient received a saline infusion combined with propofol

Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University; The First Affiliated Hospital of Anhui Medical University, Climbing the peak plan discipline construction project

Sleep disorder

 

 

Recruiting

1

120

 

Dexmedetomidine treatment; 0.2mg/kg Esketamine in combination with dexmedetomidine therapy; 0.25mg/kg Esketamine in combination with dexmedetomidine therapy; 0.3mg/kg Esketamine in combination with dexmedetomidine therapy

Department of Anesthesiology, Changzhou Second People's Hosptial Affiliated to Nanjing Medical University; Department of Anesthesiology, Changzhou Second People's Hosptial Affiliated to Nanjing Medical University, Department-level projects

Depressive sleep disorder

 

 

Not yet recruiting

1

111

NA

Dexmedetomidine injection, Dexamethasone

Assiut University

Trauma Injury

03/25

03/25

Not yet recruiting

1

120

 

Intravenous dexmedetomidine infusion; Intravenous physiological saline infusion

The First Affiliated Hospital of Dalian Medical University; The First Affiliated Hospital of Dalian Medical University, Optional topics (self-funded)

Postoperative Pulmonary Complications

 

 

Not yet recruiting

1

120

RoW

Dexmedetomidine, Melatonin, Pregabalin, Placebo

Egymedicalpedia

Endoscopic Sinus Surgery

11/24

11/24

Not yet recruiting

1

120

US

Dexmedetomidine, General anesthetic

Children's Mercy Hospital Kansas City

Anesthesia

08/25

08/26

Not yet recruiting

1

180

 

Dexmedetomidine (DEX) and transcutanclus electrical acupoint stimulation (TEAS) ;DEX + Pseudo TEAS ;TEAS + NS ;Pseudo TEAS + NS

the First People's Hospital of Changde; the First People's Hospital of Changde, self-raised

postoperative sleep disturbance

 

 

Recruiting

1

72

 

Preoperative ultrasound-guided ESPB and a postoperative multimodal analgesic regimen including sufentanil PCIA, i.v. dexmedetomidine, ibuprofen and dezocine.; Preoperative ultrasound-guided TPVB and a postoperative multimodal analgesic regimen including sufentanil PCIA, i.v. dexmedetomidine, ibuprofen and dezocine.; and a postoperative multimodal analgesic regimen including sufentanil PCIA, i.v. dexmedetomidine, ibuprofen and dezocine.

Beijing Children's Hospital, National Center for Children's Health, Capital Medical University; Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Wu Jieping Medical Foundation Special Fund for Clinical Research [Grant No. 320.6750.19089-102]

lung diseases

 

 

Not yet recruiting

1

48

 

Dextrose taken orally+3 μg/kg dexmedetomidine nasal drops ; Esketamine+Midazolam oral solution mixture is taken orally+1 μg/kg dexmedetomidine nasal drops ; Esketamine+Midazolam oral solution mixture is taken orally+2 μg/kg dexmedetomidine nasal drops ; Esketamine+Midazolam oral solution mixture is taken orally+3 μg/kg dexmedetomidine nasal drops 3 μg/kg dexmedetomidine nasal drops

Xi'an International Medical Center Hospital; Xi'an International Medical Center Hospital, self-funded

None

 

 

Not yet recruiting

1

88

 

① After the surgical position was placed, the loading dose of dexmedetomidine was injected immediately (0.5μg/kg, 10 minutes); Esketamine was also pumped at 0.02mg/kg/h② After disinfection, sufentanil was given 0.05μg/kg; ① After the surgical position was placed, the loading dose of dexmedetomidine was injected immediately (0.5μg/kg, 10 minutes); At the same time, 0.02ml/kg/h pump was injected with equal volume of normal saline② After disinfection, sufentanil was given 0.05μg/kg.

he Second Hospital of Shandong University; The Second Hospital of Shandong University, Department self-financingThe department is self-funded

Degenerative lesions of the lumbar spine

 

 

Recruiting

1

104

US

Hypoxia Exposure, Phenylephrine, Phenylephrine Hydrochloride, Dexmedetomidine, Phentolamine, Phentolamine mesylate, Norepinephrine

University of Missouri-Columbia

Obesity, Healthy, Vasoconstriction, Vasodilation

06/25

06/25

Withdrawn

1

56

US

Atipamezole & Caffeine, Antisedan, Dexmedetomidine Hydrochloride & Saline, Precedex

University of Chicago

Emergence From Anesthesia

04/26

05/26