Tremfya (guselkumab) / Otsuka, MorphoSys, Novartis, J&J 
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59 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Tremfya (guselkumab) / J&J
2021-000465-32: Guselkumab versus Placebo for the Treatment of Psoriatic Arthritis Axial Disease in Bio-naive Participants Srovnání guselkumabu s placebem v léčbě psoriatické artritidy s axiálním postižením u pacientů, kteří se zatím biologiky neléčili

Ongoing
4
405
RoW, Europe
guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, JANSSEN CILAG INTERNATIONAL NV, Janssen Pharmaceutica N.V., Janssen Pharmaceutica, N.V.
Active Psoriatic Arthritis Axial Disease, Psoriasis Arthritis, Diseases [C] - Immune System Diseases [C20]
 
 
2020-004061-39: Effect of Guselkumab on Cardiovascular Risk Surrogate Markers in Patients With Moderate to Severe Plaque Psoriasis

Ongoing
4
50
Europe
Guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Pharmaceutica NV
Plaque Psoriasis, Psoriasis, Diseases [C] - Immune System Diseases [C20]
 
 
2019-002383-27: An explorative psoriasis biomarker study

Not yet recruiting
4
50
Europe
Solution for injection in pre-filled pen, Tremfya 100 mg solution for injection in pre-filled pen
Centre for Human Drug Research, Janssen-Cilag B.V.
Psoriasis, Psoriasis, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
G-CARE, NCT05125679 / 2020-004061-39: Effect of Guselkumab on Cardiovascular Risk Surrogate Markers in Participants With Moderate to Severe Plaque Psoriasis

Terminated
4
15
Europe
Guselkumab
Janssen-Cilag Ltd., Janssen Pharmaceutica NV
Psoriasis
07/23
07/23
NCT04914429: A Study of Guselkumab (TREMFYA) in Chinese Participants With Moderate to Severe Plaque Psoriasis

Completed
4
327
RoW
Guselkumab, TREMFYA, Placebo
Janssen Research & Development, LLC
Psoriasis
09/23
09/23
TIG, NCT04645355: Guselkumab Immunogenetics

Recruiting
4
25
US
Guselkumab
University of California, San Francisco, Janssen Biotech, Inc.
Psoriasis Guttate, Plaque Psoriasis
01/25
01/25
PAMPA, NCT05004727: Multi-Center Study

Recruiting
4
350
Canada, US
Guselkumab, Placebo
NYU Langone Health, Janssen Scientific Affairs, LLC
Psoriasis
12/25
03/26
STAR, NCT04929210 / 2021-000465-32: A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

Recruiting
4
405
Europe, Canada, US, RoW
Guselkumab, TREMFYA, Placebo
Janssen Research & Development, LLC, Janssen Pharmaceutica N.V., Janssen Pharmaceutica, N.V.
Arthritis, Psoriatic
03/26
11/26
NCT05858632: Immune Spatial Features of Guselkumab Cutaneous Response

Recruiting
4
10
US
Guselkumab
University of California, San Francisco, Janssen Scientific Affairs, LLC
Psoriasis of Scalp
06/26
06/26
2021-006282-37: Efficacy, Safety, and Pharmacokinetics of Guselkumab in Pediatric Participants with Moderately to Severely Active Crohn’s Disease

Ongoing
3
120
Europe, RoW, Canada, Japan, US
Guselkumab, CNTO1959, Solution for infusion, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Research & Development
Moderately to Severely Active Crohn’s Disease, Moderately to Severely Active Crohn’s Disease, Diseases [C] - Digestive System Diseases [C06]
 
 
2018-001238-16: A Study to Evaluate Further Therapeutic Strategies with Guselkumab in Patients with Moderate-to-Severe Plaque-Type Psoriasis

Not yet recruiting
3
950
Europe
Guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen-Cilag International N.V., Janssen-Cilag International NV, Janssen Pharmaceutica NV
Moderate to Severe Plaque Type Psoriasis, Psoriasis, Diseases [C] - Immune System Diseases [C20]
 
 
2020-004981-20: A Study of the Efficacy and Safety of Guselkumab in Participants with Active Psoriatic Arthritis

Ongoing
3
950
Europe, RoW
guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Research & Development
Psoriatic arthritis (PsA), Psoriatic arthritis (PsA), Diseases [C] - Immune System Diseases [C20]
 
 
2021-000482-32: A Phase 3B, study of Guselkumab in Participants with ActivePsoriatic Arthritis who had an Inadequate Response and/or Intolerance to One Prior Anti-Tumor Necrosis Factor α Agent

Ongoing
3
450
Europe
guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Pharmaceutica N.V.
Psoriatic Arthritis, Psoriatic Arthritis, Diseases [C] - Immune System Diseases [C20]
 
 
GUIDE, NCT03818035: A Study to Evaluate Further Therapeutic Strategies With Guselkumab in Participants With Moderate-to-Severe Plaque-Type Psoriasis

Checkmark Safety and efficacy data from GUIDE in psoriasis at EADV 2022
Sep 2022 - Sep 2022: Safety and efficacy data from GUIDE in psoriasis at EADV 2022
Active, not recruiting
3
880
Europe
Guselkumab, TREMFYA, Placebo Injection
Janssen-Cilag International NV
Psoriasis
03/22
07/25
2020-006165-11: GRAVITI - A Phase 3 Study to Evaluate the Efficacy and Safety of Guselkumab Subcutaneous Induction Therapy in Participants with Moderately to Severely Active Crohn’s Disease GRAVITI - Estudio de fase 3 para evaluar la eficacia y la seguridad del tratamiento de inducción con guselkumab subcutáneo en participantes con enfermedad de Crohn activa de grado moderado o severo

Ongoing
3
318
Europe, RoW
Guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, JANSSEN CILAG INTERNATIONAL NV, Janssen Research & Development
Moderately to Severely Active Crohn's Disease Enfermedad de Crohn activa de grado moderado o severo, Inflammatory bowel disease (IBD) Enfermedad inflamatoria intestinal, Diseases [C] - Immune System Diseases [C20]
 
 
2021-000491-10: FUZION - Efficacy and Safety of Guselkumab in Participants with Fistulizing, Perianal Crohn’s Disease Účinnost a bezpečnost přípravku guselkumab u pacientů s fistulující formou perianální Crohnovy nemoci

Ongoing
3
280
RoW, Europe
Guselkumab, CNTO1959, Solution for infusion, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Research & Development
Fistulizing perianal Crohn's Disease, Inflammatory bowel disease (IBD), Diseases [C] - Immune System Diseases [C20]
 
 
2020-005503-40: Study to Evaluate the Efficacy, Pharmacokinetics, Safety, and Immunogenicity of Subcutaneously Administered Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis Estudio para evaluar la eficacia, farmacocinética, seguridad e inmunogenicidad del ustekinumab o guselkumab administrado por vía subcutánea en participantes pediátricos con artritis psoriásica juvenil activa

Ongoing
3
80
Europe, RoW, US
Ustekinumab, Guselkumab, CNTO1275, CNTO1959, Solution for injection, Solution for injection in pre-filled syringe, STELARA®
Janssen-Cilag International NV, Janssen Research & Development, LLC
Juvenile Psoriatic Arthritis Artritis Psoriásica Juvenil, Juvenile Psoriatic Arthritis Artritis Psoriásica Juvenil, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
2022-000365-41: A Phase 3 Study to Evaluate the Efficacy and Safety of Guselkumab Subcutaneous Induction Therapy in Participants with Moderately to Severely Active Ulcerative Colitis Estudio de fase 3 para evaluar la eficacia y la seguridad del tratamiento de inducción con guselkumab subcutáneo en participantes con colitis ulcerosa activa de grado moderado a severo

Ongoing
3
399
Europe, RoW
Guselkumab, CNTO1959, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Research & Development
Moderately to Severely Active Ulcerative Colitis Colitis ulcerosa activa de grado moderado a severo, Inflammatory bowel disease (IBD) Enfermedad inflamatoria intestinal (EII), Diseases [C] - Immune System Diseases [C20]
 
 
GRAVITI, NCT05197049 / 2020-006165-11: A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

Active, not recruiting
3
350
Europe, Canada, Japan, US, RoW
Guselkumab Dose 1, Guselkumab Dose 2, Guselkumab Dose 3, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Crohn Disease
07/23
03/25
PROTOSTAR, NCT03451851 / 2017-003053-42: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

Active, not recruiting
3
120
Europe, Canada, US, RoW
Guselkumab, CNTO1959, Placebo for guselkumab, Etanercept, Enbrel
Janssen Research & Development, LLC
Psoriasis
07/23
12/26
PROGRESS, NCT05784129: A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection

Terminated
3
4
Europe, US
Guselkumab, CNTO1959, Placebo
Janssen Research & Development, LLC
Crohn's Disease
09/23
10/23
2022-002389-33: Prevention of Recurrence post Operatively with Guselkumab Relative to Endoscopy and Symptoms Prevenzione delle recidive post operatorie con guselkumab in relazione all'endoscopia e ai sintomi

Not yet recruiting
3
370
Europe
Guselkumab, [CNTO1959], Solution for injection
JANSSEN CILAG INTERNATIONAL NV, Janssen-Cilag International NV, Janssen Research & Development
Crohn's Disease After Surgical Resection Malattia di Crohn dopo resezione chirurgica, Inflammatory bowel disease (IBD) Malattia infiammatoria dell'intestino, Diseases [C] - Immune System Diseases [C20]
 
 
QUASAR Jr, NCT06260163: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Recruiting
3
120
Europe, Japan, US, RoW
Guselkumab Subcutaneous, CNTO1959, TREMFYA, Guselkumab Intravenous
Janssen Research & Development, LLC
Colitis, Ulcerative
05/28
08/28
NCT04397263: A Study of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Hourglass Feb 2024 - Jun 2024 : Data from trial for moderate-to-severe Crohn's disease
Active, not recruiting
3
38
Japan
Guselkumab, CNTO1959
Janssen Pharmaceutical K.K.
Crohns Disease
02/24
06/25
REASON, NCT06408935: Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Recruiting
3
112
RoW
Guselkumab, CNTO1959; TREMFYA
Janssen-Cilag Ltd.
Crohn's Disease
06/27
08/28
ASTRO, NCT05528510 / 2022-000365-41: A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Hourglass Jan 2023 - Dec 2023 : Data from ASTRO trial for ulcerative colitis
Active, not recruiting
3
418
Europe, Canada, Japan, US, RoW
Guselkumab Dose 1, Guselkumab Dose 2, Guselkumab Dose 3, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Colitis, Ulcerative
04/24
10/25
APEX, NCT04882098 / 2020-004981-20: A Study of Guselkumab in Participants With Active Psoriatic Arthritis

Recruiting
3
950
Europe, Canada, US, RoW
Guselkumab, CNTO 1959, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Arthritis, Psoriatic
01/25
12/27
FUZION CD, NCT05347095 / 2021-000491-10: A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Recruiting
3
280
Europe, Canada, Japan, US, RoW
Guselkumab, CNTO1959, Placebo
Janssen-Cilag Ltd., Janssen Research & Development
Fistulizing Crohns Disease, Perianal Crohns Disease
03/25
11/27
SPECTREM, NCT06039189: Study of Guselkumab Versus Placebo for the Treatment of Low Body Surface Area Moderate Plaque Psoriasis

Active, not recruiting
3
338
Canada, US
Guselkumab, CNTO1959, Tremfya, Placebo
Janssen Research & Development, LLC
Moderate Plaque Psoriasis
04/25
05/25
NCT05631457: Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Not yet recruiting
3
300
US
Guselkumab Prefilled Syringe [Tremfya], Tremfya, Golimumab, Simponi
University of Pennsylvania, Janssen Scientific Affairs, LLC
Psoriatic Arthritis
05/25
05/25
VISIBLE, NCT05272150: Study of Guselkumab in Skin of Color Participants With Moderate-to-severe Plaque and/or Scalp Psoriasis

Active, not recruiting
3
213
Canada, US
Guselkumab, CNTO1959, Tremfya, Placebo
Janssen Research & Development, LLC
Plaque Psoriasis, Scalp Psoriasis
05/25
05/25
SOLSTICE, NCT04936308 / 2021-000482-32: Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent

Active, not recruiting
3
453
Europe, US, RoW
Guselkumab, Tremfya, CNTO1959, Placebo
Janssen Research & Development, LLC, Janssen Pharmaceutica N.V.
Arthritis, Psoriatic
12/25
07/26
EVOLUTION, NCT05669833: Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

Recruiting
3
150
US
Guselkumab, Tremfya, Golimumab, Simponi
University of Pennsylvania, Janssen Scientific Affairs, LLC
Psoriatic Arthritis
05/26
05/26
PSUMMIT-Jr, NCT05083182 / 2020-005503-40: A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis

Recruiting
3
60
Europe, US, RoW
Ustekinumab, CNTO1275, STELARA, Guselkumab, CNTO1959, TREMFYA
Janssen Research & Development, LLC, Janssen Research & Development, LLC
Arthritis, Juvenile
11/26
08/27
MACARONI-23, NCT05923073 / 2021-006282-37: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

Recruiting
3
120
Europe, Japan, US, RoW
Guselkumab, CNTO1959, TREMFYA, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Crohn's Disease
10/27
04/28
QUASAR, NCT04033445 / 2018-004002-25: A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Hourglass May 2019 - Dec 2023 : Regulatory submission in EU
Hourglass May 2019 - Dec 2023 : Regulatory submission in US for ulcerative colitis
Checkmark Safety and efficacy data from QUASAR study for the treatment of ulcerative colitis
Oct 2022 - Oct 2022: Safety and efficacy data from QUASAR study for the treatment of ulcerative colitis
Checkmark Data from QUASAR trial for ulcerative colitis
More
Active, not recruiting
2/3
1064
Europe, Canada, Japan, US, RoW
Placebo, Guselkumab
Janssen Research & Development, LLC
Ulcerative Colitis
09/23
10/27
GALAXI, NCT03466411 / 2017-002195-13: A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Hourglass May 2019 - Dec 2023 : Regulatory submission in EU for ulcerative colitis
Checkmark Efficacy and safety data of GALAXI 1 in adult patients with moderately to severely active Crohn's disease
May 2022 - May 2022: Efficacy and safety data of GALAXI 1 in adult patients with moderately to severely active Crohn's disease
Checkmark Efficacy and safety data from GALAXI 1 trial for adults with moderately to severely active Crohn's disease
Nov 2021 - Nov 2021: Efficacy and safety data from GALAXI 1 trial for adults with moderately to severely active Crohn's disease
More
Active, not recruiting
2/3
1409
Europe, Canada, Japan, US, RoW
Guselkumab Dose 1, Guselkumab Dose 2, Guselkumab Dose 3, Guselkumab Dose 4, Guselkumab Dose 5, Guselkumab, Ustekinumab, Placebo
Janssen Research & Development, LLC
Crohn's Disease
10/23
06/30
2017-003249-18: TIGERS study proposes to take mini fragments of synovial tissue to study the molecular patterns present in psoriatic arthritis, in order to to identify markers of disease progression and response to treatment with Ustekinumab, Guselkumab or Adalimumab to analyze and compare different expression patterns within synovial and cutaneous tissue , and to investigate whether molecular diagnosis allows to predict the evolution of the disease in the long term, as well as the therapeutic response.

Not yet recruiting
2
36
Europe
Ustekinumab, adalimumab, L04AC05, Powder and solvent for solution for injection, Solution for infusion, Solution for injection in pre-filled syringe, Tremfya 100 mg solution for injection in pre-filled syringe., STELARA® 45 mg/0.5 mL or 90 mg/mL solution in a single-dose prefilled syringe, Humira 40 mg solution for injection in pre-filled syringe
Cliniques Universitaires Saint-Luc, Janssen Pharmaceutica
Psoriatic arthritis (PsA), Psoriatic arthritis (PsA) is a type of chronic inflammatory arthritis, Diseases [C] - Immune System Diseases [C20]
 
 
2018-001048-70: Comparison of secukinumab versus guselkumab in clearing psoriatic plaques refractory to ustekinumab

Not yet recruiting
2
40
Europe
Secukinumab, Tremfya, AIN457, Solution for injection in pre-filled syringe, Solution for injection, Cosentyx, Tremfya
Novartis Pharma AG, Novartis Pharma AG
Plaque Psoriasis, Psoriasis looks like red, raised scaly areas of the skin, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
2020-000622-26: A Proof-of-Concept Study of Guselkumab in the Treatment of Subjects with New-Onset or Relapsing Giant Cell Arteritis

Not yet recruiting
2
60
Europe
Guselkumab, CNTO1959, Solution for infusion, Solution for injection
Janssen-Cilag International N.V., JANSSEN CILAG INTERNATIONAL NV, Janssen Pharmaceutica N.V., Janssen Research R&D
Giant Cell Arteritis, Giant Cell Arteritis, Diseases [C] - Immune System Diseases [C20]
 
 
2018-004451-20: A multicenter, open label, single-arm pilot study to evaluate the efficacy and safety of guselkumab in patients with moderate to severe palmoplantar pustulosis (PPP) Multizentrische, offene, einarmige Pilotstudie zur Bewertung der Wirksamkeit und Sicherheit von Guselkumab bei Patienten mit mittelschwerer bis schwerer, palmoplantarer Pustulose (PPP)

Not yet recruiting
2
50
Europe
Guselkumab, CNTO 1959, Solution for injection in pre-filled syringe
Rheinische Friedrich-Wilhelms-Universität Bonn, Janssen-Cilag GmbH
Adult men and women with palmoplantar pustulosis Erwachsene männliche und weibliche Probanden mit palmoplantarer Pustulose, Adult men and women with palmoplantar pustulosis Erwachsene männliche und weibliche Probanden mit palmoplantarer Pustulose, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
2021-000271-36: Immunotherapy with the bioactive substance Guselkumab in patients suffering from oral skin disease Lichen-Planus using an open-label, parallel, multi-center phase IIa trial design

Not yet recruiting
2
45
Europe
Guselkumab, Solution for infusion in pre-filled syringe, Tremfya
Philipps University Marburg, Janssen-Cilag GmbH
severe oral lichen planus (LP) with variable phenotype (erosive, ulcerating, hyperplastic/leucoplastic, and combined forms), severe oral skin disease lichen planus (LP) with variable outer appearance, Diseases [C] - Skin and Connective Tissue Diseases [C17]
 
 
2021-002012-31: A Study of the Efficacy and Safety of Guselkumab and Golimumab in Participants with Active Psoriatic Arthritis Estudio para evaluar la eficacia y la seguridad de Guselkumab y Golimumab en pacientes con artritis psoriásica activa

Ongoing
2
90
Europe
guselkumab, golimumab, CNTO1959, CNTO148, Solution for injection in pre-filled syringe
Janssen-Cilag International NV, JANSSEN CILAG INTERNATIONAL NV, Janssen Research & Development
Active Psoriatic Arthritis Artritis Psoriásica Activa, Psoriatic Arthritis Artritis Psoriásica, Diseases [C] - Immune System Diseases [C20]
 
 
2018-001510-15: A Proof-of-concept Study of the Efficacy and Safety of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Not yet recruiting
2
210
Europe
Guselkumab, Golimumab, CNTO1959, CNTO148, Solution for infusion in pre-filled syringe, Solution for injection in pre-filled syringe, TREMFYA®, Simponi®
Janssen-Cilag International NV, Janssen Research & Development, LLC
Ulcerative Colitis, Inflammation of Digestive Tract, Diseases [C] - Digestive System Diseases [C06]
 
 
2018-003155-38: A Study of the Efficacy and Safety of Guselkumab in Participants with Active Lupus Nephritis

Not yet recruiting
2
60
Europe
Guselkumab, CNTO1959, Solution for injection in pre-filled syringe, TREMFYA
Janssen-Cilag International NV, Janssen Research & Development
Active Lupus Nephritis, Active Lupus Nephritis, Diseases [C] - Immune System Diseases [C20]
 
 
ORCHID-LN, NCT04376827: A Study of Guselkumab in Participants With Active Lupus Nephritis

Terminated
2
33
Europe, US, RoW
Guselkumab Dose 1, CNTO 1959, Placebo, Guselkumab Dose 2, CNTO1959, Standard-of-care treatment
Janssen Research & Development, LLC
Lupus Nephritis
02/23
02/23
NCT04683029: A Study of Guselkumab in Participants With Systemic Sclerosis

Active, not recruiting
2
56
Japan
Guselkumab Dose 1, Guselkumab Dose 2, Placebo
Janssen Pharmaceutical K.K.
Scleroderma, Systemic
05/23
07/24
THEIA, NCT04633447: A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis

Terminated
2
53
Europe, Canada, US, RoW
Guselkumab, Tremfya, CNTO 1959, Placebo
Janssen Research & Development, LLC
Giant Cell Arteritis
05/24
05/24
AFFINITY, NCT05071664 / 2021-002012-31: A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis

Completed
2
91
Europe, US, RoW
Guselkumab, TREMFYA, CNTO1959, Golimumab, SIMPONI, CNTO148, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Arthritis, Psoriatic
05/24
08/24
DUET-CD, NCT05242471 / 2021-003314-39: A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Active, not recruiting
2
703
Europe, Canada, Japan, US, RoW
Guselkumab, Golimumab, JNJ-78934804, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Crohn's Disease
05/25
01/31
DUET-UC, NCT05242484 / 2021-005528-39: A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Active, not recruiting
2
577
Europe, Canada, Japan, US, RoW
Guselkumab, Golimumab, JNJ-78934804, Placebo
Janssen Research & Development, LLC, Janssen Research & Development
Colitis, Ulcerative
05/25
03/29
GEORGE, NCT06563323: Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG)

Not yet recruiting
2
17
US
Guselkumab, Tremfya
Oregon Health and Science University, Janssen Scientific Affairs, LLC, Ohio State University
Pyoderma Gangrenosum, Skin Diseases, Wound Heal, Pyoderma, Skin Ulcer
08/27
08/27
NCT04948398: Post-Trial Access for Guselkumab in Participants With Familial Adenomatous Polyposis

No Longer Available
N/A
NA
Guselkumab
Janssen Research & Development, LLC
Adenomatous Polyposis Coli
 
 
NCT04394936: An Explorative Psoriasis Biomarker Study

Recruiting
N/A
50
Europe
Guselkumab, Placebos
Centre for Human Drug Research, Netherlands, Janssen Pharmaceuticals
Psoriasis Vulgaris
10/22
12/22
TIGERS, NCT04261010: TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_() Study

Completed
N/A
36
Europe
Global/single cell gene expression profiles obtained from Synovial biopsies
Cliniques universitaires Saint-Luc- Université Catholique de Louvain, Janssen-Cilag International NV, University Hospital, Ghent
Psoriatic Arthritis
09/23
09/23
GULLIVER, NCT04439526: A Study of Guselkumab in Naive or Bio-experienced Participants With Regional (Facial and Genital) Psoriasis

Completed
N/A
356
Europe
Guselkumab, Tremfya
Janssen-Cilag S.p.A.
Psoriasis
11/23
11/23
NCT06586281: Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy

Recruiting
N/A
20
US
Guselkumab, Tremfya
University of California, San Diego, Janssen Scientific Affairs, LLC
Psoriatic Arthritis
09/26
12/26
NCT02103361: Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

Recruiting
N/A
200
US
Ustekinumab, Stelara, Guselkumab, Tremfya
University of California, San Diego, The Organization of Teratology Information Specialists, Janssen Biotech, Inc.
Psoriasis, Pregnancy, Psoriatic Arthritis, Crohn Disease
12/24
12/25
PsABIOnd, NCT05049798: A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Active, not recruiting
N/A
1314
Europe, Canada, Japan, RoW
Guselkumab, TREMFYA, IL-17i
Janssen Pharmaceutica N.V., Belgium
Arthritis, Psoriatic
08/27
08/27

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