Hypertension, Pulmonary  >>  Tracleer (bosentan)  >>  Phase 4
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Tracleer (bosentan) / J&J, Roche
NCT00317486: Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Completed
4
54
US, Canada, Europe, RoW
bosentan
Actelion
Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
04/05
04/05
NCT00367770: BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Completed
4
37
US, Canada, Europe, RoW
Tracleer®
Actelion
Pulmonary Arterial Hypertension
12/05
12/05
NCT00120380: Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH)

Terminated
4
40
Europe
Aerosolized iloprost, Placebo
Hannover Medical School
Hypertension
05/06
05/06
NCT00082186 / 2004-004391-36: The Effect of Tracleer® on Male Fertility

Completed
4
22
US, Europe, RoW
bosentan, Tracleer (R)
Actelion
Hypertension, Pulmonary
02/07
11/07
NCT00595049: Pulmonary Artery Remodelling With Bosentan

Completed
4
11
RoW
bosentan, Tracleer
Actelion
Hypertension, Pulmonary
12/08
06/10
COMPASS 3, NCT00433329: Combination Therapy in Pulmonary Arterial Hypertension

Completed
4
100
US
Bosentan, Sildenafil
Actelion
Pulmonary Arterial Hypertension
05/10
08/10
SCOBA-PH, NCT01330108: Safely Change From Bosentan to Ambrisentan in Pulmonary Hypertension

Completed
4
32
US
ambrisentan, Letairis
University of Alabama at Birmingham
Pulmonary Arterial Hypertension
06/12
06/12
NCT00679068: Effects of Bosentan on Respiratory Mechanics

Terminated
4
4
Europe
Bosentan
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pulmonary Hypertension
12/12
06/13
Compass-2, NCT00303459 / 2005-005068-97: Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)

Completed
4
334
US, Europe, RoW
bosentan, placebo
Actelion
Pulmonary Arterial Hypertension
12/13
12/13
NCT01508780: Combined Use of Angiography, Optical Coherence Tomography and Intravascular Ultrasound in Evaluation of Pulmonary Vascular Structure and Function in Patients With Pulmonary Arterial Hypertension Treated With Oral Bosentan

Withdrawn
4
0
US
St Jude Medical C7 Dragonfly Optical Coherence Tomography (OCT), Boston Scientific Intravascular Ultrasound
Massachusetts General Hospital, Actelion
Pulmonary Arterial Hypertension
02/14
02/14
Letairis, NCT02885012: Crossover Study From Macitentan or Bosentan Over to Ambrisentan

Terminated
4
3
US
Ambrisentan, Letairis
Medical University of South Carolina, Ochsner Health System
Pulmonary Arterial Hypertension
07/17
07/17

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