| Tracleer (bosentan) / J&J, Roche |
NCT00432978: Effect of Bosentan on Exercise Capacity at High Altitude |
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| Completed | 1 | 20 | US | Bosentan administration | VA Loma Linda Health Care System, Actelion | Altitude, Pulmonary Hypertension | | 02/07 | | |
NCT01100736: Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3) |
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| Completed | 1 | 10 | Europe | Bosentan, Tracleer, Sitaxsentan, Thelin, Placebo, Endothelin-3 | University of Edinburgh, Encysive Pharmaceuticals | Pulmonary Arterial Hypertension, Vasodilation, Vasoconstriction | 09/09 | 01/10 | | |
NCT01864863: To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male Volunteers |
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| Completed | 1 | 28 | RoW | HGP1206, Bosentan 125 mg, Traclear, Traclear 62.5 mg | Hanmi Pharmaceutical Company Limited | Pulmonary Arterial Hypertension | 05/13 | 05/13 | | |
| Completed | 1 | 44 | Europe | BIA 5-1058, Zamicastat, bosentan, Tracleer | Bial - Portela C S.A. | Pulmonary Arterial Hypertension | 05/18 | 05/18 | | |
NCT06484673: Bioequivalence Study to Compare Bosentan 32 mg Dispersible Tablets Versus Tracleer® 32 mg Tablets |
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| Completed | 1 | 32 | RoW | Bosentan Dispersible Tablets, Tracleer Tablet for Oral Suspension | Humanis Saglık Anonim Sirketi | Pulmonary Arterial Hypertension | 05/24 | 05/24 | | |
