Central Nervous System Diseases  >>  telcagepant (MK-0974)  >>  Phase 3
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6 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
telcagepant (MK-0974) / Merck (MSD)
NCT00442936: Study of Telcagepant (MK-0974) in Participants With Moderate to Severe Acute Migraine With or Without Aura (MK-0974-011)

Completed
3
1380
NA
Telcagepant potassium 150 mg, Telcagepant potassium 300 mg, Zolmitriptan 5 mg, Placebo to telcagepant 150 mg, Placebo to tecagepant 300 mg, Placebo to zolmitriptan 5 mg, Rescue medication
Merck Sharp & Dohme LLC
Migraine
10/07
10/07
NCT00432237 / 2006-006187-35: Safety and Efficacy Study of MK0974 in the Acute Migraine (0974-016)

Completed
3
1703
US
MK0974 50 mg, MK0974, MK0974 150 mg, MK0974 300 mg, Comparator: Placebo
Merck Sharp & Dohme LLC
Migraine
12/07
12/07
NCT00443209: Telcagepant (MK-0974) Long-Term Safety Study in Adult Participants With Acute Migraine (MK-0974-012)

Completed
3
1068
NA
Telcagepant 300 mg soft gel capsules, Telcagepant 280 mg tablets, Rizatriptan 10 mg tablets, Placebo to telcagepant capsules, Placebo to telcagepant tablets, Placebo to rizatriptan tablets
Merck Sharp & Dohme LLC
Migraine
01/09
01/09
NCT00483704: Multiple Attacks Study to Compare the Efficacy and Safety of MK-0974 With Placebo for Acute Migraine (MK-0974-031)

Completed
3
1935
NA
Telcagepant 140 mg, Talcagepant 280 mg, Placebo
Merck Sharp & Dohme LLC
Migraines
03/09
03/09
NCT00662818: Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)

Completed
3
165
NA
Telcagepant, Acetaminophen/Paracetamol, Placebo to Telcagepant, Placebo to Acetaminophen/Paracetamol
Merck Sharp & Dohme LLC
Migraine Disorders, Heart Disease, Cerebrovascular Accident, TIA (Transient Ischemic Attack), Vascular Diseases, Peripheral Vascular Diseases
09/09
09/09
NCT01125774: Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)

Completed
2/3
4548
NA
Telcagepant, MK-0974, Placebo
Merck Sharp & Dohme LLC
Migraine
04/11
04/11

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