| Rencarex (girentuximab) / Heidelberg Pharma, Esteve, Merck (MSD) |
2008-004548-35: PHASE II STUDY OF LUTETIUM-177 LABELED CHIMERIC MONOCLONAL ANTIBODY cG250 (177Lu-DOTA-cG250) IN PATIENTS WITH ADVANCED RENAL CANCER |
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| Ongoing | 2 | 9 | Europe | cG250, cG250, | Radboud university nijmegen medical centre | Patients with metastatic clear cell renal cell carcinoma | | | | |
OPALESCENCE, NCT04758780: Imaging Performance Assessment of 89Zirconium-labelled Girentuximab (89Zr-TLX250) PET-CT in Metastatic Triple Negative Breast Cancer Patients |
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| Recruiting | 2 | 12 | Europe | 89Zr-TLX250 PET/CT | Institut Cancerologie de l'Ouest, Telix Pharmaceutical, SIRIC ILIAD | Triple Negative Breast Cancer | 03/24 | 06/24 | | |
| Recruiting | 2 | 41 | US | 177Lu-labeled-girentuximab, Nivolumab, 89Zr-girentuximab PET/CT, 177Lu whole body (WB) planar and SPECT/CT scans | Memorial Sloan Kettering Cancer Center | Clear Cell Renal Cell Carcinoma, Kidney Cancer, Advanced Renal Cell Carcinoma | 03/25 | 03/25 | | |
NCT05563272: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors |
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| Recruiting | 2 | 100 | US | 89Zr-DFO-girentuximab | Telix International Pty Ltd | Cervical Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Glioblastoma Multiforme, Cholangiocarcinoma, Hepatocellular Carcinoma, Head and Neck Squamous Cell Carcinoma, Nasopharyngeal Carcinoma, Non Small Cell Lung Cancer, Small Cell Lung Cancer, Epithelial Ovarian Cancer, Pancreatic Ductal Adenocarcinoma, Soft Tissue Sarcoma | 12/25 | 12/25 | | |
| Recruiting | 1/2 | 12 | RoW | 89Zr-Girentuximab | Telix International Pty Ltd | Urothelial Carcinoma, Bladder Cancer | 02/22 | 05/22 | | |
NCT05663710: Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment Naïve Patients with Advanced Clear Cell RCC |
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| Active, not recruiting | 1/2 | 100 | US | 177Lu girentuximab, Nivolumab, BMS-936558, Opdivo, Cabozantinib, XL-184, XL184, ArabinoFuranosylGuanine [18F]F-AraG | M.D. Anderson Cancer Center, Telix Pharmaceuticals Limited | Advanced Cancer, Clear Cell Renal Cell Carcinoma | 10/25 | 10/27 | | |
