| Rencarex (girentuximab) / Heidelberg Pharma, Esteve, Merck (MSD) |
| Completed | 3 | 300 | Europe, Canada, US, RoW | 89Zr-girentuximab, 89Zr-TLX250, 89Zr-DFO-TFP-girentuximab (GTX) | Telix Pharmaceuticals (Innovations) Pty Limited | Clear Cell Renal Cell Carcinoma | 10/22 | 11/22 | | |
NCT05563272: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors |
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| Recruiting | 2 | 100 | US | 89Zr-DFO-girentuximab | Telix International Pty Ltd | Cervical Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Glioblastoma Multiforme, Cholangiocarcinoma, Hepatocellular Carcinoma, Head and Neck Squamous Cell Carcinoma, Nasopharyngeal Carcinoma, Non Small Cell Lung Cancer, Small Cell Lung Cancer, Epithelial Ovarian Cancer, Pancreatic Ductal Adenocarcinoma, Soft Tissue Sarcoma | 12/25 | 12/25 | | |
| Recruiting | 1/2 | 12 | RoW | 89Zr-Girentuximab | Telix International Pty Ltd | Urothelial Carcinoma, Bladder Cancer | 02/22 | 05/22 | | |
ZiPUP, NCT05046665: Phase I Study to Evaluate the Diagnostic Performance of 89Zirconium Girentuximab PET in Urothelial Cancer Patients |
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| Completed | 1 | 11 | RoW | 89Zr-Girentuximab | South Metropolitan Health Service, Telix Pharmaceuticals (Innovations) Pty Limited | Urothelial Carcinoma | 08/22 | 08/22 | | |
ZIRDOSE-CP, NCT05861778: Evaluation of 89Zr-TLX250 PET/CT in Chinese Patients With Indeterminate Renal Masses or Suspected Recurrent Renal Clear Cell Carcinoma |
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| Completed | 1 | 10 | RoW | 89Zr-Girentuximab, 89Zr-DFO-girentuximab, 89Zr-TLX250, TLX250CDx | Telix International Pty Ltd, Grand Pharmaceutical (China) Co., Ltd. | Clear Cell Renal Cell Carcinoma, Suspected Recurrent Renal Clear Cell Carcinoma, Recurrent Renal Cell Cancer | 11/23 | 11/23 | | |
NCT05868174: Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors |
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| Recruiting | 1 | 36 | RoW | 89Zr-TLX250, 89Zr-DFO-girentuximab, 177Lu-TLX250 and Peposertib, 177Lu-DOTA-girentuximab | Telix Pharmaceuticals (Innovations) Pty Limited, Merck KGaA, Darmstadt, Germany | Solid Tumor, Adult, Advanced Solid Tumor, Advanced Renal Cell Carcinoma | 12/24 | 12/26 | | |