Ongoing

4

200

Europe

SABRIL SACHETS, SYNACTHEN DEPOT, SOLUBLE PREDNISOLONE TABLETS, SABRIL SACHETS, SYNACTHEN DEPOT, SOLUBLE PREDNISOLONE TABLETS

Royal United Hospital Bath NHS Trust, , Castang Foundation, NIHR, Bath Unit for Research in Paediatrics, Bronner/Bender Stiftung

Infantile spasms are a rare severe form of epilepsy affecting approx 1 in 2,250 infants, usually under the age of 1 year. Affected infants have a very abnormal EEG and a poor prognosis for subsequent epilepsy and neuro-development. There is a high risk of underlying neurological disease that independently causes delayed development and other seizure disorders. There is a high risk of a poor outcome even when there is no other detectable underlying neurological disorder.