| Completed | 2 | 111 | Europe | temozolomide, temsirolimus | European Organisation for Research and Treatment of Cancer - EORTC, Pfizer | Brain and Central Nervous System Tumors | 12/13 | 03/14 | | |
NCT01614795: Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma |
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| Completed | 2 | 46 | Canada, US | Cixutumumab, Anti-IGF-1R Recombinant Monoclonal Antibody IMC-A12, IMC-A12, Laboratory Biomarker Analysis, Temsirolimus, CCI-779, CCI-779 Rapamycin Analog, Cell Cycle Inhibitor 779, Rapamycin Analog, Rapamycin Analog CCI-779, Torisel | National Cancer Institute (NCI) | Childhood Alveolar Soft Part Sarcoma, Childhood Angiosarcoma, Childhood Epithelioid Sarcoma, Childhood Fibrosarcoma, Childhood Gliosarcoma, Childhood Leiomyosarcoma, Childhood Liposarcoma, Childhood Malignant Peripheral Nerve Sheath Tumor, Childhood Synovial Sarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Osteosarcoma, Rhabdomyosarcoma | 04/14 | 04/14 | | |
NCT00022724: CCI-779 in Treating Patients With Malignant Glioma |
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| Completed | 1/2 | 49 | US | temsirolimus | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI) | Brain and Central Nervous System Tumors | 05/06 | 12/07 | | |
NCT00112736: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma |
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| Completed | 1/2 | 69 | US | erlotinib, CP-358,774, erlotinib hydrochloride, OSI-774, temsirolimus, CCI-779, cell cycle inhibitor 779, Torisel, therapeutic conventional surgery, laboratory biomarker analysis, pharmacological study, pharmacological studies | National Cancer Institute (NCI) | Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Diffuse Astrocytoma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma, Adult Mixed Glioma, Adult Pilocytic Astrocytoma, Adult Pineal Gland Astrocytoma, Adult Subependymal Giant Cell Astrocytoma, Recurrent Adult Brain Tumor | 04/10 | 04/14 | | |
