Neoplasm Metastasis  >>  Torisel (temsirolimus)  >>  Phase 1
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6 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Torisel (temsirolimus) / Pfizer
NCT00003712: CCI-779 in Treating Patients With Advanced Solid Tumors

Completed
1
15
US
temsirolimus
The University of Texas Health Science Center at San Antonio, National Cancer Institute (NCI), University of Texas, Wyeth is now a wholly owned subsidiary of Pfizer
Brain and Central Nervous System Tumors, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
06/02
06/02
NCT00593060: Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer

Completed
1
35
US
Temsirolimus, Torisel, CCI-779, Cetuximab, Erbitux
Jeffrey W. Clark, MD, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Wyeth is now a wholly owned subsidiary of Pfizer
Colorectal Cancer, Colorectal Adenocarcinoma
10/09
11/10
NCT00784914: A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors

Completed
1
12
US
temsirolimus, pharmacological study, cytokine levels
City of Hope Medical Center, National Cancer Institute (NCI)
Brain and Central Nervous System Tumors, Metastatic Cancer
11/10
11/10
NCT00678769: Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic Cancer

Checkmark P1 data
Mar 2012 - Mar 2012: P1 data
Checkmark P1 data
Jul 2011 - Jul 2011: P1 data
Completed
1
72
US
Cixutumumab, Anti-IGF-1R Recombinant Monoclonal Antibody IMC-A12, IMC-A12, Laboratory Biomarker Analysis, Pharmacological Study, Temsirolimus, CCI-779, CCI-779 Rapamycin Analog, Cell Cycle Inhibitor 779, Rapamycin Analog, Rapamycin Analog CCI-779, Torisel
National Cancer Institute (NCI)
Malignant Neoplasm
06/13
10/15
NCT01183663: Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

Checkmark Lenalidomide in combination with temsirolimus in pts with adv cancer
Aug 2013 - Aug 2013: Lenalidomide in combination with temsirolimus in pts with adv cancer
Checkmark ASCO 2013
May 2013 - May 2013: ASCO 2013
Checkmark Data-AACR
More
Completed
1
180
US
Lenalidomide, CC-5013, Revlimid, Bevacizumab, Avastin, Anti-VEGF monoclonal antibody, rhuMAB-VEGF, Sorafenib, Nexavar, BAY 43-90006, Temsirolimus, CC-779, Torisel, Oxaliplatin, Eloxatin, Leucovorin, Citrovorum, Wellcovorin, 5-fluorouracil, 5-FU, Adrucil, Efudex
M.D. Anderson Cancer Center, Celgene
Advanced Cancers
05/16
05/16
NCT00761644: Doxil, Bevacizumab and Temsirolimus Trial

Checkmark
May 2013 - May 2013: 
Completed
1
200
US
Doxil, Liposomal doxorubicin, Doxorubicin hydrocholoride (liposomal), Bevacizumab, Avastin, Anti-VEGF monoclonal antibody, rhuMAb-VEGF, Temsirolimus, CCI-779, Torisel
M.D. Anderson Cancer Center
Advanced Cancer
03/19
03/19

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