levetiracetam / Generic mfg.  >>  Phase 2
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21 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
levetiracetam / Generic mfg.
2008-001098-13`ACTRN12617001195347: Simultaneous administration of lorazepam and levetiracetam in non-convulsive status epilepticus, followed by IV valproate: a prospective, randomized, placebo-controled, double-blind pilot trial.

Ongoing
2
80
Europe
LEVETIRACETAM, L059, KEPPRA®, KEPPRA®
UZ Leuven, Department of Health, Western Australia
Peanut allergy
 
 
2020-003698-24: A study to investigate JNJ-40411813 in combination with levetiracetam in epilepsy

Ongoing
2
112
Europe
JNJ-40411813, JNJ-40411813, Tablet
Janssen-Cilag International NV, Janssen Research and Development LLC, US
Focal Onset Seizures, Seizures, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT01857934: Therapy for Children With Advanced Stage Neuroblastoma

Active, not recruiting
2
153
US
cyclophosphamide, Cytoxan(R), topotecan, Hycamtin(R), hu14.18K322A, humanized anti-GD2 antibody, monoclonal antibody, dinutuximab, peripheral blood stem cell harvest, PBSCH, surgical resection, cisplatin, Platinol-AQ(R), etoposide, VP16, Vepesid(R), Etopophos(R), doxorubicin, Adriamycin(R), vincristine, Oncovin(R), busulfan, Busulfex(R), melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran(R), peripheral blood stem cell transplantation, PBSCT, natural killer cell infusion, NK cell infusion, radiation therapy, GM-CSF, sargramostim, Leukine(R), granulocyte macrophage colony stimulating factor, G-CSF, Granulocyte colony stimulating factor, Neupogen(R), Filgrastim, mesna, Mesnex(R), levetiracetam, Keppra, interleukin-2, IL-2, aldesleukin, Proleukin(R), Isotretinoin, 13-cis retinoic acid, CliniMACS, Cell Selection System
St. Jude Children's Research Hospital, Cookies for Kids' Cancer, CURE Childhood Cancer, Inc.
Neuroblastoma
10/21
12/24
LEVNEONAT-1, NCT02229123 / 2014-000791-26: Levetiracetam Treatment of Neonatal Seizures: Safety and Efficacy Phase II Study

Completed
2
18
Europe
Intravenous Levetiracetam
University Hospital, Tours, Assistance Publique - Hôpitaux de Paris, Rennes University Hospital, Amiens University Hospital
Neonatal Seizures
02/22
02/22
ILiAD, NCT03489044 / 2016-003109-32: An Investigation of Levetiracetam in Alzheimer's Disease

Completed
2
8
Europe
Levetiracetam, Placebo Oral Tablet
University of Oxford, Oxford University Hospitals NHS Trust, Oxford Health NHS Foundation Trust, Northumberland, Tyne and Wear NHS Foundation Trust, UCB Pharma
Alzheimer Disease, Epilepsy
03/22
03/22
TRIP, NCT04643327: Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease

Recruiting
2
28
RoW
Levetiracetam, Placebo
The University of Queensland, Queensland University of Technology, Johns Hopkins University, Cleveland Clinic Lou Ruvo Center for Brain Health, Royal Brisbane and Women's Hospital
Parkinson Disease, Mild Cognitive Impairment, Memory Impairment
01/25
12/25
NCT03875638: Treating Hyperexcitability in AD With Levetiracetam

Recruiting
2
85
US
Levetiracetam, Placebo oral capsule
Beth Israel Deaconess Medical Center
Alzheimer Dementia, Alzheimer Disease, Dementia of Alzheimer Type, Mild Cognitive Impairment
10/24
11/24
NCT04317807: R33: Levetiracetam in Early Psychosis

Recruiting
2
84
US
Levetiracetam Pill, Keppra, Placebo
NYU Langone Health
Early Psychosis
01/25
01/25
NCT04836559 / 2020-003698-24: A Study to Investigate JNJ-40411813 in Combination With Levetiracetam or Brivaracetam in Epilepsy

Completed
2
110
Europe, US, RoW
JNJ-40411813, Placebo
Janssen Research & Development, LLC, Janssen Research and Development LLC, US
Focal Onset Seizures
02/24
02/24
NCT06345495: High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

Not yet recruiting
2
30
US
Ruxolitinib, Jakafi, INCB018424, INC424, Allogeneic Stem Cell Transplantation, Autologous stem cell transplant, Cord Blood, Levetiracetam, Eltrombopag, Promacta®, Busulfan, Busulfex™, Myleran®, Romiplostim, AMG 531, Nplate, Fludarabine phosphate, Fludarabine, Fludara®, Cyclophosphamide, Cytoxan®, Neosar®, Mesna, Mesnex™, Tacrolimus, Prograf®
M.D. Anderson Cancer Center, Incyte Corporation
Splenomegaly, Myelofibrosis
01/27
01/29
LAPSE, NCT04004702: Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial

Not yet recruiting
2
65
US
Levetiracetam, Keppra
Walter Reed National Military Medical Center
Alzheimer Disease
12/24
06/25
NCT04559529: Pharmacological Modulation of Hippocampal Activity in Psychosis 2

Completed
2
62
US
Levetiracetam (LEV) 500 mg, Keppra, Placebo
Vanderbilt University Medical Center
Schizophrenia; Psychosis
12/23
12/23
NEOLEV3, NCT05610085: A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures

Recruiting
2
133
US, RoW
Levetiracetam Injection, Phenobarbital Sodium Injection
University of California, San Diego, University of Minnesota, Rady Children's Hospital, San Diego, Auckland City Hospital, University of Auckland, New Zealand, Middlemore Hospital, New Zealand
Neonatal Seizure, Neonatal Encephalopathy, Hypoxic-Ischemic Encephalopathy, Seizure Newborn
07/27
12/27
NCT05735717: MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Recruiting
2
150
US
Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam, Keppra
Masonic Cancer Center, University of Minnesota
Hematologic Malignancy, Acute Leukemia, Remission, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, AML, TP53, Intrachromosomal Amplification of Chromosome 21, Cytogenetic Abnormality, CNS Leukemia, Minimal Residual Disease, Myelodysplasia, Juvenile Myelomonocytic Leukemia, Somatic Mutation, PTPN11 Gene Mutation, N-RAS Gene Amplification, Neurofibromatosis 1, NF1 Mutation, CBL Gene Mutation, Monosomy 7, Chromosome Abnormality, Fetal Hemoglobin
11/27
11/30
2006-006804-12: Levetiracetam (Keppra®) in neonates

Ongoing
1/2
10
Europe
Keppra, Keppra
ErasmusMedical Center-Sophia
epileptic seizures in neonates admitted to the intensive care unit
 
 
NCT02602015: Levetiracetam Treatment of Neonatal Seizures

Not yet recruiting
1/2
100
RoW
Oral levetiracetam, Keppra, Intravenous phenobarbital, phenobarbitone
The People's Hospital of Dehong Autonomous Prefecture, Children's Hospital of Fudan University, Xiamen Children's Hospital, Fujian of China, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Guangzhou Women and Children's Medical Center, Second Affiliated Hospital of Wenzhou Medical University, Maternal and Child Health Hospital of Hubei Province
Neonatal Seizures
12/18
12/18
ZUMA-1, NCT02348216 / 2015-005007-86: Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma

Checkmark Data from ZUMA-1 trial for R/R LBCL at ASH 2022
Dec 2022 - Dec 2022: Data from ZUMA-1 trial for R/R LBCL at ASH 2022
Checkmark Presentation from ZUMA-1 trial for DLBCL at ASTCT 2021
Feb 2021 - Feb 2021: Presentation from ZUMA-1 trial for DLBCL at ASTCT 2021
Checkmark Presentation from ZUMA-1 trial for DLBCL at ASH 2020
More
Completed
1/2
307
Europe, Canada, US, RoW
Axicabtagene Ciloleucel, Yescarta®, Fludarabine, Cyclophosphamide, Levetiracetam, Tocilizumab, Dexamethasone, High-dose methylprednisolone, Bendamustine, Rituximab, Doxorubicin, Prednisone, Vincristine, Ifosfamide, Carboplatin, Etoposide, Gemcitabine, Oxaliplatin, Cisplatin, Methylprednisolone
Kite, A Gilead Company
Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B-Cell Lymphoma, Transformed Follicular Lymphoma (TFL), Primary Mediastinal B-cell Lymphoma (PMBCL), High Grade B-cell Lymphoma (HGBCL)
07/23
07/23
NCT04497142: Effect of Perampanel on Peritumoral Hyperexcitability in HGG

Completed
1/2
12
US
Perampanel, E2007, Fycompa, Standard of Care, Standard treatment (typically the anti-seizure medication levetiracetam)
Dana-Farber Cancer Institute, National Cancer Institute (NCI), Eisai Inc.
Glioma, Malignant, Surgery, Seizures
05/23
05/23
CAN-GT, NCT04833907: rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease

Recruiting
1/2
24
US
rAAV-Olig001-ASPA, MYR-101, Levetiracetam, Keppra, Prednisone
Myrtelle Inc.
Canavan Disease
08/26
08/27
NCT03034356: Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia

Completed
1/2
67
US
Levetiracetam, Keppra, Placebo
VA Office of Research and Development
Schizophrenia
06/24
06/24
NCT02550028: Levetiracetam Treatment of Neonatal Seizures

Terminated
1/2
60
RoW
Oral levetiracetam, Keppra, Intravenous phenobarbital, phenobarbitone
Children's Hospital of Fudan University, Xiamen Children's Hospital, Fujian of China, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Guangzhou Women and Children's Medical Center, Second Affiliated Hospital of Wenzhou Medical University, Maternal and Child Health Hospital of Hubei Province, The Maternal & Children Health Hospital of Dehong, Yunnan of China
Neonatal Seizures
01/17
01/17

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