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Threonine-Tyrosine Kinase Inhibitors
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Phase 2
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Phase
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1
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Trials
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mirdametinib
(PD-0325901) / SpringWorks Therap, BeiGene
pimasertib
(AS703026) / Day One Biopharma
refametinib
(BAY86-9766) / Bayer
Hocena
(antroquinonol) / Golden Biotechnology
E6201
/ Strategia Therap
REC-4881
/ Recursion Pharma
SHR7390
/ Jiangsu Hengrui Pharma
NFX-179
/ NFlection Therap
zapnometinib
(ATR-002) / Atriva Therap
CI-1040
/ Pfizer
GDC-0623
/ Roche
WX-554
/ Heidelberg Pharma
IMM-1-104
/ Immuneering
IMM-6-415
/ Immuneering
trametinib repurposed
(SNR1611) / GENUV
