Glucocorticoid Receptor 

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  • ||||||||||  methylprednisolone sodium succinate / Generic mfg.
    [VIRTUAL] Rehabilitation of Acute Myelitis Secondary to COVID-19 Vaccine: A Case Report () -  Nov 1, 2021 - Abstract #AAPMR2021AAPMR_662;    
    Treatment for acute myelitis consisted of IV Solu-Medrol followed by plasma exchange (PLEX)... This case highlights the role neuro-rehabilitation units serve in the rehabilitation of patients who have developed unexpected complications secondary to the COVID-19 pandemic.
  • ||||||||||  dexamethasone / Generic mfg., gabapentin / Generic mfg.
    [VIRTUAL] COVID-19 Related Plexopathy Without Prone Positioning: A Case Study () -  Nov 1, 2021 - Abstract #AAPMR2021AAPMR_643;    
    Additionally, we face the threat of future novel viruses. Continued research into the neurologic sequelae of patients afflicted with this infection will guide future treatments and rehabilitation.
  • ||||||||||  dexamethasone / Generic mfg.
    [VIRTUAL] Interventional Management of Thoracic Pain Secondary to Malignant Pleural Effusion: A Case Report () -  Nov 1, 2021 - Abstract #AAPMR2021AAPMR_573;    
    After the catheter removal, he developed severe right-sided thoracic pain unresponsive to tramadol, oxycodone, and dilaudid...He was taken to the fluoroscopy suite where he underwent an ultrasound guided erector spinae plane block to the right T7 paraspinal level with a mixture of 0.5% lidocaine, 0.5% bupivacaine, and 10 mg dexamethasone... We report a case in which an erector spinae plane nerve block was successfully used to treat cancer related thoracic neuralgia unresponsive to post-surgical pain medications.
  • ||||||||||  ketorolac / Generic mfg., dexamethasone / Generic mfg.
    [VIRTUAL] Acute Calcific Tendinitis of the Longus Colli Muscle: A Case Report () -  Nov 1, 2021 - Abstract #AAPMR2021AAPMR_545;    
    Calcific tendinitis of the longus colli muscle is a rare pathology important to consider on the differential for acute neck pain. It can present similar to more severe conditions, though with proper imaging, it is easily diagnosed and treated with conservative management.
  • ||||||||||  dexamethasone / Generic mfg., gabapentin / Generic mfg., memantine / Generic mfg.
    [VIRTUAL] Palato-pharyngo-laryngeal Myoclonus as a Rare Cause of Dysphagia: A Case Report () -  Nov 1, 2021 - Abstract #AAPMR2021AAPMR_508;    
    This case depicts the importance of evaluating for palatal myoclonus as part of the dysphagia assessment. Along with identifying abnormalities in the GMT area, MRI can assist with early detection and prospective medical interventions.
  • ||||||||||  methylprednisolone sodium succinate / Generic mfg.
    [VIRTUAL] Acute Transverse Myelitis Following COVID-19 Vaccination: A Case Report () -  Nov 1, 2021 - Abstract #AAPMR2021AAPMR_465;    
    Setting : Inpatient rehabilitation facility Assessment/Results : The patient underwent treatment with intravenous methylprednisolone and her condition began to improve... While there is currently insufficient data to form a direct association between the COVID-19 vaccine and transverse myelitis, it is vitally important for healthcare professionals to remain vigilant for potential adverse events and report them to the FDA as appropriate.
  • ||||||||||  dexamethasone / Generic mfg., clarithromycin / Generic mfg., pomalidomide / Generic mfg.
    Trial completion date, Trial primary completion date:  Autologous Stem Cell Transplant With Pomalidomide (CC-4047 (clinicaltrials.gov) -  Nov 1, 2021   
    P2,  N=23, Active, not recruiting, 
    Future studies are needed to evaluate for long-term effects of frequent and high doses of corticosteroid injections on male reproductive function. Trial completion date: Dec 2021 --> Dec 2022 | Trial primary completion date: Dec 2021 --> Dec 2022
  • ||||||||||  prednisone / Generic mfg., methylprednisolone sodium succinate / Generic mfg., azathioprine / Generic mfg.
    Journal:  Vogt-Koyanagi-Harada-like Disease following Yellow Fever Vaccination. (Pubmed Central) -  Oct 31, 2021   
    No recurrence of intraocular inflammation or sign of depigmentation was so far noticed, at 2 years of follow-up. Yellow fever vaccine may be a possible trigger for VKH.
  • ||||||||||  rifampicin / Generic mfg.
    Clinical, Journal:  Hemophagocytic Lymphohistiocytosis Associated with Disseminated Nontuberculous Mycobacterial Infection in a Patient with Mesenteric Panniculitis. (Pubmed Central) -  Oct 31, 2021   
    He was treated with oral prednisolone (15 mg/day) and cyclosporin A (150 mg/day) at presentation...An anti-mycobacterial chemotherapy including chloramphenicol (800 mg/day), rifampin (450 mg/day) and ethambutol (750 mg/day) together with streptomycin (750 mg twice per week) was initiated at 30 days after admission; maintenance doses of prednisolone were increased to 60 mg/day...The present case suggests that mesenteric panniculitis could be complicated with hemophagocytic lymphohistiocytosis caused by immunosuppressive therapy-associated infections as well as underlying disease activity. In conclusion, the possibility of disseminated nontuberculous mycobacteria infection with hemophagocytic lymphohistiocytosis should be considered if unexplained fever or hematological dyscrasia were presented in patients of mesenteric panniculitis.
  • ||||||||||  Darzalex IV (daratumumab) / J&J
    Clinical, Journal, Real-world evidence:  First-line daratumumab shows high efficacy and tolerability even in advanced AL amyloidosis: the real-world experience. (Pubmed Central) -  Oct 31, 2021   
    In conclusion, the possibility of disseminated nontuberculous mycobacteria infection with hemophagocytic lymphohistiocytosis should be considered if unexplained fever or hematological dyscrasia were presented in patients of mesenteric panniculitis. Daratumumab proved to be highly effective in newly diagnosed AL amyloidosis with excellent hematologic and organ response rates, a remarkable safety profile, and good tolerability even in patients with advanced stage of disease.
  • ||||||||||  methylprednisolone acetate / Generic mfg.
    Clinical, Journal:  Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study. (Pubmed Central) -  Oct 31, 2021   
    We found that PRP renders similar results to that of corticosteroids in most clinical aspects among patients with RC tendinopathies; however, pain and ROM may show more significant improvement with the use of PRP. Considering that the use of corticosteroids may be contraindicated in some patients and may be associated with the risk of tendon rupture, we suggest the use of PRP in place of corticosteroid-based injections among patients with RC tendinopathy.
  • ||||||||||  dexamethasone / Generic mfg.
    Journal:  Dermal Olfactory Receptor OR51B5 Is Essential for Survival and Collagen Synthesis in Human Dermal Fibroblast (Hs68 Cells). (Pubmed Central) -  Oct 31, 2021   
    We confirmed that UVB irradiation and dexamethasone exposure significantly decreased cell survival and collagen synthesis in Hs68 dermal fibroblasts...OR51B5 knockdown decreased cAMP levels and dampened the downstream protein kinase A/cAMP-response element binding protein pathway, downregulating the survival- and collagen synthesis-related genes in the dermal fibroblasts. Therefore, OR51B5 may be an interesting candidate that plays a role in cell survival and collagen synthesis.
  • ||||||||||  hydrocortisone / Generic mfg.
    Journal:  Idiopathic combined adrenocorticotropin and growth hormone deficiency mimicking chronic fatigue syndrome. (Pubmed Central) -  Oct 31, 2021   
    Treatment with a physiologic dose of oral hydrocortisone replacement physically ameliorated his general fatigue...Here, we present a rare case of combined deficiency of ACTH and GH in a middle-aged man with severe general fatigue. This case report aims to raise awareness of combined deficiency of ACTH and GH as a differential diagnosis of CFS and its mimics.
  • ||||||||||  budesonide / Generic mfg.
    Review, Journal:  Controversials of Microscopic Colitis. (Pubmed Central) -  Oct 31, 2021   
    Why would biologics be effective in these cases when budesonide is not? This mini-review makes an attempt to summarize the data about MC and highlight that there are still unanswered questions in the pathogenesis, diagnosis and therapy of the disease, which can initiate further investigations in the future.
  • ||||||||||  dexamethasone / Generic mfg., enoxaparin sodium / Generic mfg.
    The prospect of using the ESP-block for anesthesia of patient with COVID - 19. Clinical case. (Channel 1 - ePosters [VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_943;    
    After 24 hours, the patient was transferred to the surgical department, with further recovery. Performing general surgical interventions in the conditions of the ESP-block or the inclusion of the ESP-block in the anesthesia regimen is an effective, safe and promising technique that allows to reduce the risks of both the patient with COVID-19 and the anesthesia team.
  • ||||||||||  dexamethasone / Generic mfg., metamizole / Generic mfg.
    Efficacy and safety of metamizole in pain management after scheduled craniotomy ([VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_750;    
    Metamizole supply adequate analgesia after scheduled craniotomy. No important bleeding, renal impairment, hypermagnesemia, or agranulocytosis were found secondary to the use of metamizole in caucasian people submitted to scheduled craniotomy
  • ||||||||||  ketamine / Generic mfg.
    Outpatient surgery is not always smooth: a case of anaphylaxis. (Channel 1 - ePosters [VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_595;    
    Anesthesia was induced with infusion of remifentanil (0.01 mcg/kg/min) and propofol (6 mg/kg/h)...Immediate therapy was started with rocuronium (70mg IV), adrenaline (1mg IM + 1mg IV), ketamine (100mg IV), magnesium sulfate (2g IV), clemastine (2g IV) and hydrocortisone (200mg IV)...The fact that tryptase levels remain normal may be a factor against anaphylaxis although tryptase level does not always rise (2). In this case, it will be important to clarify differential diagnoses of anaphylaxis, airway manipulation and hereditary and acquired angioedema.
  • ||||||||||  dexamethasone / Generic mfg.
    Perioperative anesthetic considerations for Fabry disease during emergency surgery (Channel 1 - ePosters [VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_579;    
    Monitored neuromuscular blockade was reversed with sugammadex...Pain was managed with paracetamol, metamizole and morphine...Learning points:The main problem with Fabry disease comes with renal and cardiac organic impairment. During perioperative care close monitoring should be done so a correct systemic perfusion is guaranteed and no organ dysfunction appears, particularly with special reference to lung, heart, brain and kidneys.
  • ||||||||||  Dynastat (parecoxib) / Pfizer
    Hepatic hydatid cyst excision via robotic surgery – A case report (Channel 1 - ePosters [VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_578;    
    Prophylactic administration of hydrocortisone 100mg was given...Analgesia intra-operatively was performed with fentanil (total dose 250 mcg), paracetamol 1g, metamizole 2g, tramadol 200mg and parecoxib 40mg...World Health Organization states that protoscolicidal substances (ex:20% hypertonic saline left for 15 minutes) may be used in case of spillage but their effect are questionable due to their possible toxicity. We describe the anesthetic management of a successful resection with hydatid cyst rupture with no perioperative complication Learning Points: Robotic assisted hydatid cyst resection is a viable surgical option. Cyst rupture is a possible complication of the technique.
  • ||||||||||  hydrocortisone / Generic mfg.
    Bilateral palsy of hypoglossal (XII) nerve following general anaesthesia for emergency surgery (Channel 1 - ePosters [VIRTUAL]) -  Oct 31, 2021 - Abstract #Euroanaesthesia2021Euroanaesthesia_560;    
    Hydrocortisone 200mg/24hr for 4 days was prescribed without however any significant improvement...As the hypoglossal nerve has a superficial course beneath the angle of the mandible, nerve damage is also possible during mask ventilation. Learning points: Due to the rarity of the syndrome, vigilance is required for early diagnosis and optimal outcome.