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- | dexamethasone / Generic mfg.
New P3 trial: Bupivicain vs Bupivicain Plus Dexamethasone in ESP Block for Post-op Analgesia (clinicaltrials.gov) - Mar 13, 2022
P3, N=30, Recruiting, Sponsor: Sheikh Zayed Medical College
- || budesonide / Generic mfg.
Another question is whether EATL is preventable in RCDII? Can we ⬇️ this risk (which is ~50%/5 yrs) by specific follow-up and Tx? If a RCDII pt is feeling OK on budesonide 6-9mg/d but there is still villous atrophy in biopsies,should we use more aggressive Tx, knowing its risks? (Twitter) - Mar 13, 2022
- ||| methylprednisolone sodium succinate / Generic mfg.
Hello, I have a situation I'd love to get Dr Zamboni's opinion on. In December of 2017, I had a plasmapharesis treatment for a relapse that was not responding to Solumedrol. I received an IJ cath, and completed the procedure. Shortly after, I developed extreme pain in the right (Twitter) - Mar 12, 2022
- || dexamethasone / Generic mfg., Keytruda (pembrolizumab) / Merck (MSD)
How much dexamethasone would you typically use for KN 355 when picking carbo and gem as a partner for pembro? @hoperugo (Twitter) - Mar 12, 2022
- || Darzalex IV (daratumumab) / J&J
Clinical, Journal, Combination therapy: Safety and Effectiveness of Weekly Carfilzomib, Lenalidomide, Dexamethasone, and Daratumumab Combination Therapy for Patients With Newly Diagnosed Multiple Myeloma: The MANHATTAN Nonrandomized Clinical Trial. (Pubmed Central) - Mar 12, 2022
There were no deaths. In this nonrandomized clinical trial, carfilzomib-lenalidomide-dexamethasone-daratumumab combination therapy was associated with high rates of MRD negativity in patients with newly diagnosed multiple myeloma and high rates of PFS.
- || dexamethasone / Generic mfg., lenalidomide / Generic mfg.
Review, Journal: Update on the Diagnosis and Treatment of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome: A Review. (Pubmed Central) - Mar 12, 2022
Lenalidomide and dexamethasone can be prescribed for patients who are ineligible for transplants...POEMS syndrome should be considered in the differential diagnosis for patients who have peripheral neuropathy and paraproteinemia among other multisystem manifestations. The syndrome can be debilitating if not recognized early in its course; thus, appropriate diagnosis and treatment are important for optimal clinical outcomes.
- ||| budesonide / Generic mfg.
Budesonide in very small doses reduces cranial heat and swelling within 15 minutes. But that's not enough: we need to open constricted circulation from the temporal bones down to the foramen magnum. (Twitter) - Mar 12, 2022
- |||| budesonide / Generic mfg.
Clinical: Or do you just order a 'throat' swab, put a child on quarantine and NOT SEE THEM again? I'm arguing that every pediatrician and family medicine doctor should discuss STOIC, acknowledge limitations of that study, and offer budesonide to prevent brain swelling? (Twitter) - Mar 12, 2022
- |||| budesonide / Generic mfg.
Clinical: Preventing 'post-viral syndrome' is another reason for emergency authorization of nebulized budesonide for children. Not by itself but with percussion therapy to dislodge the adhesions before fibrosis becomes irreversible. (Twitter) - Mar 12, 2022
- | dexamethasone / Generic mfg.
Journal: Regulation of neurotropic herpesvirus productive infection and latency-reactivation cycle by glucocorticoid receptor and stress-induced transcription factors. (Pubmed Central) - Mar 12, 2022
For example, BoHV-1 and HSV-1 productive infection is impaired by glucocorticoid receptor (GR) antagonists but is stimulated by the synthetic corticosteroid dexamethasone...Hence, growing evidence suggests GR and stress-induced transcription factors directly stimulate viral gene expression and productive infection during early stages of reactivation from latency. We predict the immune inhibitory effects of stress enhance virus spread at late stages during reactivation from latency.
- | dexamethasone / Generic mfg.
Journal: Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism. (Pubmed Central) - Mar 12, 2022
Using rat primary fetal adrenal cells, the differential expression of AR and ERβ was proven to be involved in regulating the sex difference in 11β-HSD2 expression. This study demonstrated the sex difference in adrenal steroidogenic function of PDT offspring after birth and elucidated a sex hormone receptor-dependent epigenetically regulating mechanism for adrenal 11β-HSD2 programming alteration.
- | Sarclisa (isatuximab-irfc) / Sanofi
Journal: Isatuximab, carfilzomib, lenalidomide, and dexamethasone (Isa-KRd) in front-line treatment of high-risk multiple myeloma: interim analysis of the GMMG-CONCEPT trial. (Pubmed Central) - Mar 12, 2022
This study demonstrated the sex difference in adrenal steroidogenic function of PDT offspring after birth and elucidated a sex hormone receptor-dependent epigenetically regulating mechanism for adrenal 11β-HSD2 programming alteration. No abstract available
- | fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Preclinical, Journal: Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease. (Pubmed Central) - Mar 12, 2022
No abstract available It indicate that MgIG might be an alternative for COPD treatment, and its mechanism of action might be related to the suppression of NLRP3 inflammasome.
- || hydrocortisone / Generic mfg.
Clinical, Journal: Sudden cardiac arrest associated with myxedema coma due to undiagnosed hypothyroidism: a case report. (Pubmed Central) - Mar 12, 2022
Our findings are useful in the differential diagnosis of hypothyroidism based on characteristic physical examination findings. Clinicians should be aware of the differential diagnosis of myxedema coma based on findings from physical examination and laboratory testing of thyroid function, and the treatment should be started immediately.
- || dexamethasone / Generic mfg., ondansetron / Generic mfg.
Clinical, Observational data, Journal: Postdischarge pain, nausea and patient satisfaction after diagnostic and breast conserving ambulatory surgery for breast cancer: a cross sectional study. (Pubmed Central) - Mar 12, 2022
A high worst pain score and high pain score during the activity were associated with postdischarge nausea. Patient satisfaction was high.
- | dexamethasone injection / Generic mfg.
Journal: Protective effects of chlorogenic acid on the meat quality of oxidatively stressed broilers revealed by integrated metabolomics and antioxidant analysis. (Pubmed Central) - Mar 12, 2022
To investigate the protective effects of CGA on the meat quality of oxidatively stressed broilers, 240 one-day-old male Cobb broiler chickens were allocated to four treatments: basal diet (control group), basal diet + dexamethasone (DEX) injection (DEX group), basal diet containing 500 mg kg CGA (CGA group), and basal diet containing 500 mg kg CGA + DEX injection (DEX_CGA group)...Moreover, according to the correlation analysis, four metabolites were identified as potential biomarkers to predict the meat quality. In conclusion, our findings demonstrate that CGA is an effective, natural and safe antioxidant to enhance the quality of meat from intensive industrial poultry production.
- | dexamethasone / Generic mfg.
Retrospective data, Journal: Efficacy of surgeon-directed postoperative local injection with an analgesic mixture in posterior fusion surgery for adolescent idiopathic scoliosis. (Pubmed Central) - Mar 12, 2022
One-time submyofascial injections at the operated levels with a ropivacaine-epinephrine-dexamethasone mixture after spinal fusion surgery reduced pain, opioid consumption, and opioid-related adverse events. This technique can contribute significantly to postoperative analgesia.
- | dexamethasone / Generic mfg., fluocinolone acetonide / Generic mfg.
Journal: Steroid Treatment in Macular Edema: A Bibliometric Study and Visualization Analysis. (Pubmed Central) - Mar 12, 2022
Macular edema, diabetic macular edema (DME), retinal vein occlusion (RVO), dexamethasone (DEX), fluocinolone acetonide (FA), and some other keywords were commonly studied in this field...While anti-VEGF therapy is the first-line treatment for DME and RVO-induced macular edema, steroids implant is a valid option for these DME patients not responding to anti-VEGF therapy and non-DME patients with macular edema. Combined therapy with anti-VEGF and steroid agents is vital for future research.
- || dexamethasone / Generic mfg., dexmedetomidine / Generic mfg.
Retrospective data, Review, Journal: Efficacy of Dexamethasone versus Dexmedetomidine Combined with Local Anaesthetics in Brachial Plexus Block: A Meta-Analysis and Systematic Review. (Pubmed Central) - Mar 12, 2022
The present meta-analysis results affirm that dexamethasone is a better local anaesthetic adjuvant in brachial plexus block that enhances the blocking effect. Nevertheless, the existing heterogeneity warrants additional large-scale, multicentre, high-quality randomized controlled trials in the future for further verification and to provide more reliable clinical evidence.
- | methylprednisolone sodium succinate / Generic mfg.
Journal: COVID-19 Infection Or Buttock Injections? the Dangers of Aesthetics and Socializing During a Pandemic. (Pubmed Central) - Mar 12, 2022
The patient was diagnosed with silicone embolism syndrome (SES) and initiated on high dose intravenous methylprednisolone [1]...The serology and imaging findings observed in our case have similarities to the typical presentation of COVID-19 pneumonia making the initial diagnosis difficult. This case serves as a cautionary tale of the importance of thorough history taking in patients with concern for COVID-19.
- | dexamethasone / Generic mfg.
Journal: Mining electronic health records for drugs associated with 28-days mortality in COVID-19: a pharmacopoeia wide association study (PharmWAS). (Pubmed Central) - Mar 12, 2022
Our systematic analysis of early prescribed treatments from patients hospitalized for COVID-19 showed that Diazepam and Tramadol were associated with increased 28-days mortality. Whether these drugs could worsen COVID-19 needs to be further assessed.
- ||| methylprednisolone oral / Generic mfg.
cc: @jack_turban @DrHowardLiu @MGHClayCenter @mghfc @DrScottHadland @DrHinaTalib @BarbaraRoblesMD @DanielleRamo @DrLondonoTobon @JenniferLeahMD @RobertAccordino @FDP_Tweets @kevinlovefund @AACAP @AmerAcadPeds @drjessigold @SolomeTibebu @JillGrimesMD @HansaBhargavaMD (Twitter) - Mar 12, 2022
- || @GSK You still advertise on Fox after this? Imitrex (sumatriptan) Levitra (vardenafil) Augmentin (amoxicillin/clavulanate) Flovent (fluticasone) Naramig (naratriptan) Zantac (ranitidine) Wellbutrin (bupropion) Generics work. Boycott Glaxo Smith Kline. (Twitter) - Mar 12, 2022
- ||||| methotrexate / Generic mfg., methylprednisolone sodium succinate / Generic mfg.
Clinical: #Linear #scleroderma #ClinicalPearl If deep it is treated with #methotrexate and repeated doses of IV solumedrol. Thanks esp to #paediatric rheumatologists for studying how to treat it. (Twitter) - Mar 11, 2022
- | budesonide / Generic mfg.
Journal: Bile Acid Sequestrant Therapy in Microscopic Colitis. (Pubmed Central) - Mar 11, 2022
BAS may be an effective corticosteroid-sparing option in the treatment of MC and should be considered after budesonide induction. Larger controlled studies are needed to confirm the efficacy for long-term maintenance and tolerability of BAS in patients with MC.
- | dexamethasone / Generic mfg.
Preclinical, Journal, IO biomarker: Preclinical modeling of surgery and steroid therapy for glioblastoma reveals changes in immunophenotype that are associated with tumor growth and outcome. (Pubmed Central) - Mar 11, 2022
Larger controlled studies are needed to confirm the efficacy for long-term maintenance and tolerability of BAS in patients with MC. These data reveal that prior to intervention, increased tumor volume corresponds with reduced systemic immune function and that peripheral lymphocyte counts are prognostic when steroid treatment is taken into account.
- | dexamethasone / Generic mfg.
Journal: Potent immunosuppressive and anti-inflammatory bisindole alkaloids from Melodinus fusiformis. (Pubmed Central) - Mar 11, 2022
Furthermore, BIA 2 remarkably inhibited the levels of IL-6 and TNF-α compared to the LPS induced group. Interestingly, BIA 2 displayed an inhibitory effect on TNF-α production similar to that of dexamethasone at a concentration of 20 μM.
- | fluticasone / Generic mfg.
Journal: Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug repurposing in Alzheimer's disease. (Pubmed Central) - Mar 11, 2022
Propensity score-stratified cohort studies reveal that usage of mometasone (a stronger glucocorticoid receptor agonist) is significantly associated with a decreased risk of AD (HR=0.74, 95% CI 0.68-0.81, p<1.0×10-8) compared to fluticasone after adjusting age, gender, and disease comorbidities. In summary, we present a network-based, multimodal methodology for single-cell/nucleus genomics-informed drug discovery and has identified fluticasone and mometasone as potential treatments in AD.
- | dexamethasone / Generic mfg.
Journal: Phytochemical profile and antiproliferative activity of human lymphocytes of Gomphrena virgata Mart. (Amaranthaceae). (Pubmed Central) - Mar 11, 2022
Also, it was effective in reducing lymphocyte proliferation, stimulated with the mitogen PHA, by 26.02%, 48.57% and 50.49% when compared to dexamethasone, respectively. In this work we present information about the phytochemicals of G. virgata, showing that the species is promising in obtaining compounds with medicinal potential mainly anti-inflammatory potential.
- || dexamethasone / Generic mfg.
Clinical, Journal: The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals. (Pubmed Central) - Mar 11, 2022
We obtained clinical data, childhood maltreatment scores and neurocognitive performance by clinical assessment; HPA negative feedback was analysed using the dexamethasone suppression test ratio (DSTR) after administration of 0.25 mg of dexamethasone; and the FKBP5 rs1360780 polymorphism was genotyped in DNA obtained from blood samples...Our results suggest a specific impact of different kinds of childhood maltreatment on measures of neurocognition and social cognition, which might be influenced by HPA axis reactivity and genetic variants in HPA axis-related genes such as FKBP5. Disentangling the relationship between these elements and their influence on cognitive performance might help identify susceptible individuals with higher stress vulnerability and develop preventive interventions.
- | hydrocortisone / Generic mfg.
Journal: Perinatal determinants of neonatal hair glucocorticoid concentrations. (Pubmed Central) - Mar 11, 2022
In summary, neonatal hair cortisol is associated with birth gestation, maternal hair cortisol concentration and fetal growth. Additionally, exposures at delivery are important determinants of hair cortisol, and should be considered in the design of future research investigating how neonatal hair cortisol relates to prenatal exposures or fetal development.
- || hydrocortisone / Generic mfg.
Clinical, Journal: Comparison of Early Versus Late Initiation of Hydrocortisone in Patients With Septic Shock in the ICU Setting. (Pubmed Central) - Mar 11, 2022
There was no difference in mortality between groups. In this propensity-matched cohort, administration of hydrocortisone within 12 hours from the onset of septic shock was associated with improved time to vasopressor discontinuation and reduced ICU and hospital LOS.
- | risperidone / Generic mfg.
Journal: A joint method for the screening of pharmacological chaperones for phenylalanine hydroxylase. (Pubmed Central) - Mar 11, 2022
In conclusion, we established a joint method that is highly reliable, cost-effective, labor-saving, and time-saving. And we also found a specific agonist for D101N-mutated PAH by this joint method which may assist the development of clinical treatment for PAHD patients with different enzyme deficiencies.
- || dexamethasone / Generic mfg.
Clinical, Journal: Reactivation of Strongyloides stercoralis in patients with SARS-CoV-2 pneumonia receiving dexamethasone. (Pubmed Central) - Mar 11, 2022
And we also found a specific agonist for D101N-mutated PAH by this joint method which may assist the development of clinical treatment for PAHD patients with different enzyme deficiencies. No abstract available
- | dexamethasone / Generic mfg., azithromycin / Generic mfg.
Journal: Effects of intranasal azithromycin on features of cigarette smoke-induced lung inflammation. (Pubmed Central) - Mar 11, 2022
Beneficial effects of AZT functionally translated in improved lung mechanics in vivo. Further preclinical and clinical studies are warranted to fully establish and validate the therapeutic efficacy of AZT as a mono- or combination therapy for the treatment of COPD.
- | dexamethasone / Generic mfg.
Journal: A tool for evaluating novel osteoarthritis therapies using multivariate analyses of human cartilage-synovium explant co-culture. (Pubmed Central) - Mar 11, 2022
Further preclinical and clinical studies are warranted to fully establish and validate the therapeutic efficacy of AZT as a mono- or combination therapy for the treatment of COPD. The OA-EXM is representative of late-stage OA pathology, captures dual interactions between cartilage and synovium, and combined with statistical strategies provides a rapid, sensitive research tool for evaluating OA therapeutics.
- || dexamethasone / Generic mfg.
Clinical, Journal: Orthopedic Toxicities Among Adolescents and Young Adults Treated on DFCI ALL Consortium Trials. (Pubmed Central) - Mar 11, 2022
Patients with ON had superior overall survival (OS) compared to those without (multivariable OS HR 0.15 [95% CI: 0.05-0.46], p=0.001; ON included as a time-varying exposure). Increased rates of orthopedic toxicity in late generation protocols may be driven by the pharmacokinetic drug interaction between pegaspargase and dexamethasone, leading to higher dexamethasone exposure.
- || dexamethasone / Generic mfg.
Clinical, Journal: Hemophagocytic lymphohistiocytosis and thrombotic microangiopathy after parvovirus B19 infection and renal transplantation: a case report. (Pubmed Central) - Mar 11, 2022
In rare cases both HLH and aHUS can occur simultaneously in a patient as a consequence of viral infections. Insights from this unusual case might help physicians understand this complex symptom constellation.
- || methylprednisolone oral / Generic mfg.
Clinical, Journal: The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Study: Trial Design and Baseline Characteristics. (Pubmed Central) - Mar 11, 2022
Insights from this unusual case might help physicians understand this complex symptom constellation. The TESTING study (combined full and low dose) will define the benefits of corticosteroid use on major kidney outcomes, as well as the risks of therapy, and provide data on the relative effects of different doses, in individuals with high-risk IgAN.
- || Xpovio (selinexor) / Karyopharm, Menarini
Clinical, Journal: Once weekly selinexor, carfilzomib and dexamethasone in carfilzomib non-refractory multiple myeloma patients. (Pubmed Central) - Mar 11, 2022
Weekly XKd is highly effective and well-tolerated. These data support further investigation of XKd in patients with MM.
- || dexamethasone / Generic mfg.
Clinical, Journal: Elevated intraocular pressure in children with acute lymphoblastic leukaemia: A prospective study. (Pubmed Central) - Mar 11, 2022
High body mass index was an additional risk factor in children with elevated IOP at ALL diagnosis. Routine evaluation of IOP during steroid therapy is very important in children with ALL to ensure early intervention which may prevent permanent ocular damage.
- | dexamethasone / Generic mfg.
Journal: Ion drugs for precise orthotopic tumor management by in situ the generation of toxic ion and drug pools. (Pubmed Central) - Mar 11, 2022
A responsive and biodegradable biomineral, Mn-doped calcium carbonate integrated with dexamethasone phosphate (DEX) (Mn:CaCO-DEX), was reported to enable synergistic amplification of tumor oxidative stress, reduce inflammation, and induce Ca-overload cell apoptosis by elevating the intracellular and extracellular ionic gradients...Notably, normal cells showed greater tolerance of the synergistic influences. As an ion drug, Mn:CaCO-DEX is an excellent potential diagnostic agent for precise orthotopic tumor management by the generation in situ of toxic ion and drug pools in the environment of tumor region, with synergistic effects of enhanced chemodynamic therapy, calcification, and anti-inflammation effects.
- | dexamethasone / Generic mfg.
Journal: Lemongrass essential oil and its major constituent citral isomers modulate adipogenic gene expression in 3T3-L1 cells. (Pubmed Central) - Mar 11, 2022
Differentiation was conducted using DMEM enriched with 10% fetal bovine serum, Dexamethasone 0.25 µM, 3-isobutyl-methylxanthine 0.5 mM, and insulin 10 mg/ml for 2 days, followed by 5 days of insulin 10 mg/ml alone...This investigation suggests that LEO and its constituents exert effects on adipocyte metabolism and are important for understanding metabolic disease. Further investigation is required to elucidate the degree that each mechanism implicated contributes to the observed effect.
- || hydroxychloroquine / Generic mfg.
Clinical, Journal: Child Interstitial Lung Disease in an Infant with Surfactant Protein C Dysfunction due to c.202G>T Variant (p.V68F). (Pubmed Central) - Mar 11, 2022
The infant was placed on noninvasive ventilation and treated with IV Methylprednisolone, Hydroxychloroquine, and Azithromycin but did not show significant clinical and radiological improvement underwent tracheostomy and is awaiting lung transplantation at 8 months of age. The challenges interpreting the genetic results are discussed.
- || dexamethasone / Generic mfg.
Clinical, Journal, Head-to-Head: Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial. (Pubmed Central) - Mar 11, 2022
Interscalene nerve blocks with perineural liposomal bupivacaine provided effective analgesia similar to the perineural standard bupivacaine with dexamethasone. The results show that bupivacaine with dexamethasone can be used interchangeably with liposomal bupivacaine for analgesia after shoulder surgery.
- | prednisone / Generic mfg., methylprednisolone sodium succinate / Generic mfg.
Journal: The effectiveness and safety of corticosteroid therapy for IgA nephropathy with crescents: a prospective, randomized, controlled study. (Pubmed Central) - Mar 11, 2022
P2
The results show that bupivacaine with dexamethasone can be used interchangeably with liposomal bupivacaine for analgesia after shoulder surgery. Both the 1st-3rd-5th and 1st-2nd-3rd protocols can effectively alleviate proteinuria and protect renal function in IgAN patients with crescents but the 1st-2nd-3rd protocol seemed to have better effectiveness.
- | dexamethasone / Generic mfg.
Journal: Discovery of 13,15-nor-polycyclic polyprenylated acylphloroglucinols from Hypericum longistylum with anti-inflammatory activity. (Pubmed Central) - Mar 11, 2022
Spihyperglucinols A (1) and B (2), the first 13,15-nor-polycyclic polyprenylated acylphloroglucinols (PPAPs) featuring a 7/6/5 tricyclic ring system based on an unexpected bicyclo[3.2.2]nonane core, along with three new congeners, spihyperglucinols C-E (3-5), were isolated from Hypericum longistylum. Importantly, 1 and 2 displayed potential inhibitory effects on the production of nitric oxide in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages, with IC values of (8.70 ± 1.18) and (9.23 ± 1.26) μM, respectively, comparable to the positive control, dexamethasone, with an IC value of (9.76 ± 1.13) μM.
- | dexamethasone / Generic mfg.
Preclinical, Journal, IO biomarker: Anti-inflammatory effect of baicalin in rats with adjuvant arthritis and its autophagy- related mechanism. (Pubmed Central) - Mar 11, 2022
RT-PCR studies showed that the different doses of baicalin could inhibit the expression of TNF-a, IL-6, IL-1, IL-17, COX2 and COX1 in the synovial tissue (P< 0.05 or P< 0.01). Western blot studies showed that the different doses of baicalin could reduce the expression of Atg5, Atg7, Atg12, LC3-II, Beclin1 and Bcl-2 proteins, and increase the expression of Bax proteins in the synovial tissue.
- | dexamethasone / Generic mfg.
Preclinical, Journal: Tanshinone IIA alleviates ovalbumin-induced allergic rhinitis symptoms by inhibiting Th2 cytokine production and mast cell histamine release in mice. (Pubmed Central) - Mar 11, 2022
AR mice in the dose tested groups were treated with TIIA (10 mg/kg/d, ip) or dexamethasone (Dex) (2.5 mg/kg/d, oral)...Besides, TIIA reversed the promotion of histamine release (30%) and mast cell degranulation induced by C48/80. TIIA alleviates OVA-induced AR symptoms in AR mice, and may be applied as a therapeutic drug for patients with Th2-, or mast cell-allergic disorders.
- | dexamethasone injection / Generic mfg.
Retrospective data, Journal: Analgesic comparison between perineural and intravenous dexamethasone for shoulder arthroscopy: a meta-analysis of randomized controlled trials. (Pubmed Central) - Mar 11, 2022
TIIA alleviates OVA-induced AR symptoms in AR mice, and may be applied as a therapeutic drug for patients with Th2-, or mast cell-allergic disorders. Perineural and intravenous dexamethasone demonstrated comparable pain relief after shoulder arthroscopy.