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- | prednisone / Generic mfg., budesonide / Generic mfg.
Journal: Breakthrough Pneumocystis jirovecii Pneumonia in an Allogeneic Hematopoietic Stem Cell Transplant Recipient. (Pubmed Central) - Jul 9, 2024
While the patient received prophylactic treatment, there was still a breakthrough PCP infection. We highlight the risks this infection can cause and the need to promptly address these infections to prevent complications and optimize prophylactic regimens.
- | dexamethasone / Generic mfg., albendazole / Generic mfg., carbamazepine / Generic mfg.
Journal: Unmasking a Hidden Culprit: Neurocysticercosis, an Overlooked Cause of Acquired Epilepsy. (Pubmed Central) - Jul 9, 2024
This case study underscores the importance of neuroimaging in investigating patients with neurological conditions like epilepsy, especially in developing countries. Early diagnosis and effective treatment are crucial in preventing and controlling NCC, reducing its impact on public health.
- | dexamethasone injection / Generic mfg.
Journal: Uncommon Presentation of Post-Transfusion Purpura in an Elderly Male: A Case Report and Unique Alloantibody Identification. (Pubmed Central) - Jul 9, 2024
The patient was treated with supportive transfusions, dexamethasone, and intravenous immunoglobulin, with rapid platelet recovery...This report highlights the importance of monitoring patients for post-transfusion adverse events. Although PTP is rare, rapid diagnosis and management are required to control this potentially life-threatening condition.
- | dexamethasone / Generic mfg.
Enrollment change, Trial withdrawal: Dexamethasone/Pancreatic Clamp P&F (clinicaltrials.gov) - Jul 9, 2024
P1, N=0, Withdrawn, Sponsor: Columbia University
Although PTP is rare, rapid diagnosis and management are required to control this potentially life-threatening condition. N=16 --> 0 | Not yet recruiting --> Withdrawn
- |||| citarinostat (ACY-241) / BMS
Phase classification, Trial completion date, Trial termination, Trial primary completion date, Combination therapy: Study of ACY-241 Alone and in Combination With Pomalidomide and Dexamethasone in Multiple Myeloma (clinicaltrials.gov) - Jul 9, 2024
P1, N=85, Terminated, Sponsor: Celgene
N=16 --> 0 | Not yet recruiting --> Withdrawn Phase classification: P1a/1b --> P1 | Trial completion date: Jan 2024 --> Jun 2024 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2024 --> Jun 2024; Lack of efficacy
- | Aliqopa (copanlisib) / Bayer
Trial termination: Copanlisib With Dose-Adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and Other High-Grade B-cell Lymphomas (clinicaltrials.gov) - Jul 8, 2024
P1, N=8, Terminated, Sponsor: National Cancer Institute (NCI)
Phase classification: P1a/1b --> P1 | Trial completion date: Jan 2024 --> Jun 2024 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2024 --> Jun 2024; Lack of efficacy Completed --> Terminated; The study was terminated early because copanlisib was removed from the market by the Food and Drug Administration (FDA) and the manufacturer.
- | dexamethasone / Generic mfg., hydrocortisone / Generic mfg.
Journal: A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy. (Pubmed Central) - Jul 8, 2024
Completed --> Terminated; The study was terminated early because copanlisib was removed from the market by the Food and Drug Administration (FDA) and the manufacturer. Data from 30 healthy volunteers was leveraged: Endogenous ACTH and cortisol concentrations without any intervention as well as cortisol concentrations measured after dexamethasone suppression and single dose administration of (i) 0.5-10
- | ABT-737 / AbbVie
Journal: Coumarin-based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors. (Pubmed Central) - Jul 8, 2024
Data from 30 healthy volunteers was leveraged: Endogenous ACTH and cortisol concentrations without any intervention as well as cortisol concentrations measured after dexamethasone suppression and single dose administration of (i) 0.5-10 Pan-AKR1C inhibition also did not potentiate the in vitro cytotoxicity of ABT-737, daunorubicin or dexamethasone, in two patient-derived T-cell ALL and pre-B-cell ALL cell lines.
- | prednisolone / Generic mfg.
Journal: Does high hepatic bioavailability enhance the effect of oral compared to subcutaneous glucocorticoids? (Pubmed Central) - Jul 8, 2024
Short-term oral low-dose GC therapy is not more effective than parental GC in decreasing ESR, arguing against therapeutic high hepatic bioavailability effects. More likely, systemic concentration peaks following administration explain why oral physiological steroid doses are clinically effective.
- | dexamethasone / Generic mfg.
Journal: Thermal Pharyngeal Injury Resulting From Vaping: A Case Report. (Pubmed Central) - Jul 8, 2024
More likely, systemic concentration peaks following administration explain why oral physiological steroid doses are clinically effective. The patient was admitted to the hospital overnight for observation and treatment with analgesia and dexamethasone...The repeat nasopharyngolaryngoscopy showed improvement in the swelling of the epiglottis and arytenoids,
- | mometasone furoate nasal spray / Generic mfg.
Journal: Effect of Olfactory Rehabilitation on the Recovery of Post-Coronavirus Disease Olfactory Dysfunction: A Randomized Controlled Trial. (Pubmed Central) - Jul 8, 2024
Thirty-one patients were randomly assigned into three groups with 10 patients being given olfactory training (Group 1), another 10 being given mometasone furoate nasal spray/olfactory training (Group 2), and 11 patients being assigned to the control group (Group 3)...Statistically significant improvements were seen in the eODQ scores in all three groups. Conclusion No superiority of intervention for post-COVID-19 olfactory dysfunction was seen compared to control.
- | methylprednisolone sodium succinate / Generic mfg.
Journal: Rhegmatogenous Retinal Detachment in Anterior Scleritis With Ulcerative Colitis. (Pubmed Central) - Jul 8, 2024
Barricade laser was given, in addition to intravenous methylprednisolone (IVMP), followed by a tapering dose of oral prednisolone and topical dexamethasone 0.1% over three months...Treatment of non-progressive, subclinical RRD patients with UC and active AS can be delayed with regular follow-up. When RRD progressed and there was no AS activity, it was the window of opportunity for the success of scleral buckle and perioperative steroids.
- | dexamethasone / Generic mfg., carbamazepine / Generic mfg.
Journal: A Case With Twists and Turns: A Report of Vertebrobasilar Dolichoectasia. (Pubmed Central) - Jul 8, 2024
This patient trialed medical management with dexamethasone and carbamazepine with no improvement in symptoms. He then underwent surgical gamma knife treatment
- | triamcinolone acetonide / Generic mfg.
Journal: A Prospective Study of Patients Presenting With Pre-sternal Keloids. (Pubmed Central) - Jul 8, 2024
Treatment with intralesional injections of a combination of triamcinolone acetonide and hyaluronidase effectively relieves the symptoms and may be considered in patients not willing to undergo surgical intervention. Recurrences can occur and need further treatments.
- || Ocaliva (obeticholic acid) / Intercept
Review, Journal: Progress in the Management of Patients with Cholestatic Liver Disease: Where Are We and Where Are We Going? (Pubmed Central) - Jul 8, 2024
Considerable progress has been made in the management of cholestatic liver disease but there are still many opportunities and challenges. In this review, we summarized the recommended guidelines for the management of cholestatic disease and the progress of new drug research and development, in order to provide an important reference for the clinical practice of cholestatic liver disease.
- || dexamethasone / Generic mfg., lenalidomide / Generic mfg.
Review, Journal: Extramedullary Intracranial Plasmacytomas: A Systematic Review of Literature. (Pubmed Central) - Jul 8, 2024
RT alone demonstrated the highest effectiveness in managing EMIPs (30%), while QT as a sole intervention showed lower efficacy. However, a combination of dexamethasone, lenalidomide, and targeted RT displayed promising results, offering improved tumor response and increased safety.
- dexamethasone / Generic mfg., hydrocortisone / Generic mfg.
Clinical protocol, Journal: Exogenous glucocorticoids to improve extinction learning for post-traumatic stress disorder patients with hypothalamic-pituitary-adrenal-axis dysregulation: a study protocol description. (Pubmed Central) - Jul 8, 2024
P4
During next-day recall, strength of the extinction memory is determined by recovery of skin conductance and pupil dilation differential responding, whereas generalization is assessed by comparing responses between different spatial contexts. The integrated study described in the current protocol paper could inform a personalized treatment approach in which these PTSD patients may receive glucocorticoids as a treatment enhancer in trauma-focused therapies.Trial registration: The research project is registered in the European Union Drug Regulating Authorities Clinical Trials (EudraCT) database, https://eudract.ema.europa.eu/, EudraCT number 2020-000712-30.
- | dexamethasone / Generic mfg.
Retrospective data, Journal: Effect of prenatal glucocorticoid therapy on hearing screening in premature infants (Pubmed Central) - Jul 8, 2024
Among them, bronchopulmonary dysplasia was an independent risk factor forsecondary hearing screening referral?P<0.05?. A single course of adequate dexamethasone use within 48 h-7 d of prenatal has a positive effect on the preliminary hearing screening of preterm infants.
- dexamethasone injection / Generic mfg.
Efficacy of intrathyroidal dexamethasone injection in steroid-dependent subacute thyroiditis (?2 / Poster Hall) - Jul 8, 2024 - Abstract #ETA2024ETA_254;
- | dexamethasone / Generic mfg., dexmedetomidine / Generic mfg.
Enrollment status, Combination therapy, Surgery: Any: Dexmedetomidine in Postoperative Analgesia (clinicaltrials.gov) - Jul 8, 2024
P2/3, N=100, Enrolling by invitation, Sponsor: New Valley University
A single course of adequate dexamethasone use within 48 h-7 d of prenatal has a positive effect on the preliminary hearing screening of preterm infants. Recruiting --> Enrolling by invitation
- | bortezomib / Generic mfg., cyclophosphamide / Generic mfg.
Enrollment open: Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis (clinicaltrials.gov) - Jul 7, 2024
P3, N=338, Recruiting, Sponsor: SWOG Cancer Research Network
Recruiting --> Enrolling by invitation Not yet recruiting --> Recruiting
- | dexamethasone / Generic mfg., rosiglitazone / Generic mfg.
Preclinical, Journal: Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes. (Pubmed Central) - Jul 7, 2024
Additionally, the administration of rosiglitazone significantly enhances the brown and brite adipocyte phenotypes...In conclusion, EB5 and EB7 cell lines are valuable for research into adipocyte biology, providing insights into the differentiation and development of brown and beige adipocytes. Furthermore, they could be useful for the characterization of drugs targeting energy balance for the treatment of obesity and metabolic diseases.
- | methotrexate / Generic mfg.
Journal: Methotrexate might become the sole treatment option for leukemia following the occurrence of Stevens-Johnson syndrome. (Pubmed Central) - Jul 6, 2024
As far as we know, the prophylactic use of IVIG to counteract SCARs in a pediatric leukemia patient represents uncharted territory. Moreover, research into the immune system dynamics within these patients and the preservation of indispensable treatments should involve allergist-immunologists as part of the multidisciplinary team attending to neoplastic conditions.
- | belrestotug (EOS-448) / iTeos, GSK, Keytruda (pembrolizumab) / Merck (MSD)
Journal, Checkpoint inhibition: Acute Eosinophilic Pneumonia Induced by Immune Checkpoint Inhibitor and Anti-TIGIT Therapy. (Pubmed Central) - Jul 6, 2024
She was participating in a clinical trial using pembrolizumab and anti-TIGIT EOS-448, due to cancer progression...She was then empirically started on intravenous methylprednisolone for acute eosinophilic pneumonia without confirmatory bronchoscopy as she was at high risk with her previous pneumonectomy...Although bronchoscopy findings are part of AEP's diagnostic criteria, this case underscores the importance of clinical judgment in the prompt initiation of steroids, even without confirmatory bronchoscopy, in rapidly progressing cases. The role of anti-TIGIT therapy in this context remains uncertain.
- | Vyvgart (efgartigimod alfa-fcab) / argenx, Broteio
Journal: Successful treatment with efgartigimod as an add-on therapy in acute attack of anti-AQP4 antibody-positive NMOSD: a case report. (Pubmed Central) - Jul 6, 2024
The role of anti-TIGIT therapy in this context remains uncertain. This case suggests that efgartigimod is a potentially effective add-on therapy in acute attacks of AQP4-IgG-positive NMOSD.
- Kenalog-10 (triamcinolone acetonide) / BMS, Lamprene (clofazimine) / Novartis
Cheilitis Granulomatosa: A Case Review (Exhibit Hall WD1-E1, Orange County Convention Center; In-Person) - Jul 6, 2024 - Abstract #AAOMS2024AAOMS_483;
Medications including glucocorticoids (systemic, topical, intralesional), immunomodulators (clofazimine, hydroxychloroquine, fumaric acid esters), antibiotics (macrolides, tetracyclines, metronidazole), monoclonal antibodies, immunosuppressants (methotrexate, azathioprine), biologics (anti-tumor necrosis factor alpha [TNF-?]), and laser therapy have been documented in the treatment of GC6. The authors found success with a series of 4 intralesional corticosteroid injections (Kenalog 10mg/mL, 20 units per visit) resulted in remission after 3 months.
- fentanyl citrate / Generic mfg., dexamethasone / Generic mfg.
Infratemporal Fossa Dislocation of Maxillary Third Molar: Endoscopic Retrieval as a Minimally Invasive Solution to Avoid General Anesthesia: A Case Report. (Exhibit Hall WD1-E1, Orange County Convention Center; In-Person) - Jul 6, 2024 - Abstract #AAOMS2024AAOMS_451;
In summary, our case report illustrates the successful retrieval of a displaced third molar into the infratemporal fossa using an endoscopic approach and intravenous sedation. Also, it underscores the importance of training surgeons to address complications arising from in-office wisdom teeth removal, ensuring the safety of routine procedures for our patients.
- Are There Any Risk Factors for Serious Adverse Events in Procedural Outpatient Sedations by Oral and Maxillofacial Surgeons? (Tangerine Ballroom WF2, Orange County Convention Center) - Jul 6, 2024 - Abstract #AAOMS2024AAOMS_309;
A single factor was found in the study to be significantly associated with serious adverse outcome: a higher ketamine dose. This finding has not been described in previous studies on this topic, but could be explained by an unmeasured confounder, such as sedation difficulty, or could represent a type II error.
- | dexamethasone / Generic mfg.
Journal: Risk Factors Associated with Thromboembolic Complications After total Hip Arthroplasty: An Analysis of 1,129 Pulmonary Emboli. (Pubmed Central) - Jul 5, 2024
Increasing age; Black race; allogeneic blood transfusion; and comorbidities, including chronic pulmonary disease, pulmonary hypertension, and history of VTE, were independent risk factors of PE after THA. Given the increased mortality associated with PE, patients should be carefully evaluated for these factors and managed with an appropriate chemoprophylactic regimen.
- | dexamethasone / Generic mfg.
Preclinical, Journal: The therapeutic potential of Melissa officinalis L. hydroalcoholic extract and rosmarinic acid in a rat asthmatic model: A study on anti-inflammatory and antioxidant effects. (Pubmed Central) - Jul 5, 2024
Lung pathological changes were also significantly less severe in the treated groups with dexamethasone, plant extract, and RA compared to the asthma group (p<0.05 to p<0.001). This study showed that M. officinalis and RA have antioxidant and anti-inflammatory effects in an animal asthma model, suggesting their potential for treating asthma symptoms.
- | hydrocortisone / Generic mfg.
Journal, Surgery: LAPAROSCOPIC ADRENAL-SPARING SURGERY CASE SERIES: PARTIAL ADRENALECTOMY AND CYST RESECTION. (Pubmed Central) - Jul 5, 2024
All patients in groups 1 and 3 had favorable endocrinologic outcomes, and 50% of group 2 patients required lifelong hydrocortisone replacement therapy. The procedure is safe and feasible with favorable outcomes in the hands of a high volume adrenal surgeon.
- | dexamethasone / Generic mfg.
Retrospective data, Journal: Optimized high-dose granulocyte transfusions for the treatment of infections in neutropenic patients: A single-center retrospective analysis. (Pubmed Central) - Jul 5, 2024
Here, we demonstrate the successful and safe implementation of high-dose granulocyte transfusions for neutropenic patients. Given the rapid and consistent production, distribution, and improved granulocyte quality, further investigations to determine the clinical efficacy of G-CSF primed granulocyte transfusions is now possible.
- | dexamethasone / Generic mfg.
Journal: Rare Case of Adrenal Hemangioma Discovered Incidentally during Renal Colic Investigation. (Pubmed Central) - Jul 5, 2024
Dexamethasone suppression test demonstrated suppressed cortisol response, indicating a non-functional mass...These lesions are associated with a good prognosis. One limitation of this report is the lack of preoperative adrenal magnetic resonance imaging of the incidental adrenal mass.
- | Journal: In silico studies on the molecular interactions of steroid hormones and steroid hormone mimicking drugs in the androgen receptor binding cleft - Implications for prostate cancer treatment. (Pubmed Central) - Jul 4, 2024
However, hydrocortisone and bicalutamide form Arg752 and Asn705 H-bonds indicating agonism. Our results suggest that as PCa progresses the resulting mutations will change the proliferative response to androgens and their drug mimics, which have implications for the treatment of prostate cancer.
- | Blincyto (blinatumomab) / Astellas, Amgen
Journal: Blinatumomab-induced macrophage activating syndrome (MAS) in adult with B-cell acute lymphoblastic leukemia (B-ALL). (Pubmed Central) - Jul 4, 2024
Management includes holding the offending agent, like blinatumomab, and administering tocilizumab and dexamethasone. Future research will be needed to predict which patients are at highest risk to develop MAS after similar T-cell therapies.
- | Xpovio (selinexor) / Karyopharm
Retrospective data, Journal, Real-world evidence, Real-world: Real-world outcome of patients with extensively pretreated multiple myeloma who were treated with selinexor and dexamethasone: a Korean multicenter retrospective analysis. (Pubmed Central) - Jul 4, 2024
Among the patients, 12 (25%) and 17 (35%) experienced dose reduction and delayed treatment, respectively. Our data show that the real-world efficacy of XD treatment in heavily pretreated patients was modest and that improving treatment adherence through reducing initial doses or delaying treatments may improve patient outcomes.
- | dexamethasone / Generic mfg.
Journal: A dose-limited dexamethasone and bubble CPAP in ventilation-dependent extremely premature infants. (Pubmed Central) - Jul 4, 2024
- | methylprednisolone sodium succinate / Generic mfg.
Journal: Morvan Fibrillary Chorea Associated with Monoclonal B Cell Lymphocytosis. (Pubmed Central) - Jul 4, 2024
He was treated with IV methylprednisolone and IVIG, with immediate improvement in neurologic symptoms...Classically, Morvan syndrome presents as a paraneoplastic disease secondary to thymomas. Our case demonstrates that there is an association between B cell lymphoproliferative disorders and Morvan syndrome.
- | budesonide / Generic mfg.
Journal: Inflammatory eye disease is a risk factor for future microscopic colitis: A nationwide population-based matched case control study. (Pubmed Central) - Jul 4, 2024
Inflammatory eye diseases are more common in patients subsequently being diagnosed with MC. Our findings highlight that these conditions may have shared causes and inflammatory pathways and are of clinical interest to gastroenterologists, ophthalmologists and general practitioners.
- || methylprednisolone acetate / Generic mfg.
Clinical, Journal: Comparing autologous blood, corticosteroid, and a combined injection of both for treating lateral epicondylitis: a randomized clinical trial. (Pubmed Central) - Jul 4, 2024
P=N/A
Our findings highlight that these conditions may have shared causes and inflammatory pathways and are of clinical interest to gastroenterologists, ophthalmologists and general practitioners. The study concluded that while AB and CS individually offer distinct benefits, a combined AB
- || fluocinolone acetonide / Generic mfg.
Review, Journal: Histological response of inflamed pulp to hydraulic calcium silicate cements in direct pulp capping: Systematic review of pulpitis models. (Pubmed Central) - Jul 4, 2024
This systematic review could not demonstrate enhanced efficiency of capping materials compared to MTA. Future well-conducted animal studies are warranted for demonstrating the hard tissue formation abilities of pulp-capping materials with convenient inflammatory conditions.
- | triamcinolone acetonide / Generic mfg.
Retrospective data, Journal: Functional Outcomes of Fluoroscopy-Guided Intra-articular Steroids in Lumbar Facet Arthropathy: A Retrospective Comparative Study of Dexamethasone Versus Triamcinolone Acetonide. (Pubmed Central) - Jul 4, 2024
Future well-conducted animal studies are warranted for demonstrating the hard tissue formation abilities of pulp-capping materials with convenient inflammatory conditions. The main objective of this study was to assess the efficacy of IA steroid injections dexamethasone vs. triamcinolone acetonide for the treatment of LFJ syndrome and to compare functional outcome in terms of Visual Analog Scale
- | rivaroxaban / Generic mfg.
Journal: Effective Non-invasive Treatment of Lingual Hematoma in an End-Stage Renal Disease (ESRD) Patient on Rivaroxaban: A Case Report. (Pubmed Central) - Jul 4, 2024
Treatment with vitamin K, dexamethasone, tranexamic acid, and prothrombin complex concentrate led to rapid improvement without the need for intubation. This case highlights the importance of prompt medical management to prevent airway obstruction in similar patients.
- || hydrocortisone / Generic mfg.
Review, Journal: Uneventful vaginal delivery using epidural anesthesia in patient with exercise induced anaphylaxis: a case report and literature review. (Pubmed Central) - Jul 4, 2024
She delivered vaginally with no symptoms suggestive of EIA during labor. Since it is quite possible for patients with EIA to develop anaphylaxis during vaginal delivery with labor pain, epidural anesthesia and prophylactic steroid administration may be the most rational approaches for delivery in pregnant women with EIA.
- | dexamethasone / Generic mfg.
Journal: Protective effect of Sasa veitchii extract against all-trans-retinoic acid-induced inhibition of proliferation of cultured human palate cells. (Pubmed Central) - Jul 4, 2024
We demonstrated that all-trans-retinoic acid inhibited human embryonic palatal mesenchymal cell proliferation in a dose-dependent manner, whereas dexamethasone treatment had no effect on cell proliferation...Additionally, the expression levels of the genes that function downstream of the target genes ( ERBB2 and JADE1 ) of miR-4680-3p in signaling pathways were enhanced by cotreatment with Sasa veitchii extract and all-trans-retinoic acid compared to all-trans-retinoic acid treatment. These results suggest that Sasa veitchii extract suppresses all-trans-retinoic acid-induced inhibition of cell proliferation via modulation of miR-4680-3p expression.
- | prednisolone / Generic mfg., voriconazole / Generic mfg.
Journal: Allergic bronchopulmonary aspergillosis with metachronous isolation of three distinct Aspergillus species. (Pubmed Central) - Jul 4, 2024
Adjustments in therapy, including voriconazole and a tailored corticosteroid regimen, resulted in significant improvement without relapse for over 6 months. This case report highlights the challenges and successful management of ABPA involving multiple Aspergillus species.
- | Rituxan (rituximab) / Roche
Journal: Severe lupus pneumonitis: A case of life-saving multimodal therapy with rituximab and corticosteroids. (Pubmed Central) - Jul 4, 2024
This case highlights the importance of early and intensive immunosuppressive therapy in the management of severe lupus pneumonitis and underscores the utility of a multidisciplinary approach in overcoming diagnostic ambiguities. Furthermore, it contributes to the growing body of evidence supporting the efficacy of rituximab in severe lupus pneumonitis cases, offering insights into potential therapeutic avenues when conventional management strategies are inadequate or unsuitable.
- | glibenclamide / Generic mfg., dexamethasone / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg.
Journal: Quality of Essential Medicines from Different Sources in Enugu and Anambra, Nigeria. (Pubmed Central) - Jul 3, 2024
Nine out of 19 glibenclamide samples (47%) failed dissolution testing, and 7 out of 17 cotrimoxazole samples (41%) failed assay testing...Four samples (1.5%), all collected in markets, were clearly falsified and did not contain the declared active pharmaceutical ingredients. The proportion of falsified medicines was found to be lower than frequently reported in the media for Nigeria.
- | vilanterol (GW642444H) / GSK, Incruse Ellipta (umeclidinium) / GSK, Veramyst (fluticasone furoate nasal spray) / GSK
Journal: Triple Therapy and Clinical Control in B+ COPD Patients: A Pragmatic, Prospective, Randomized Trial. (Pubmed Central) - Jul 3, 2024
The proportion of falsified medicines was found to be lower than frequently reported in the media for Nigeria. The ANTES B+ study is the first to: (1) explore the efficacy and safety of triple therapy in a population of B+ COPD patients and (2) use a composite index (CC) as the primary result of a COPD trial.
- || triamcinolone acetonide / Generic mfg.
P2 data, Journal: A Phase II Clinical Trial to Study the Safety of Triamcinolone after Endoscopic Radial Incision and Cutting Dilatation for Benign Stenosis of the Lower Gastrointestinal Tract: A Study Protocol. (Pubmed Central) - Jul 3, 2024
The ANTES B+ study is the first to: (1) explore the efficacy and safety of triple therapy in a population of B+ COPD patients and (2) use a composite index (CC) as the primary result of a COPD trial. This explorative study will provide useful information regarding the safety of TA administration after RIC, which may contribute to further investigations.