- |||||||||| dexamethasone / Generic mfg.
EFFECT OF HIGH- VS LOW-DOSE OF DEXAMETHASONE ON INCIDENCE OF HOSPITAL-ACQUIRED INFECTIONS IN ACUTE HYPOXEMIC RESPIRATORY FAILURE IN SARS COV-2 PNEUMONIA (Convention Center 101BC) - Aug 16, 2022 - Abstract #CHEST2022CHEST_2028;
In hospitalized COVID-19 patients with acute respiratory failure, high dose dexamethasone use was associated with significantly higher HAP rates compared to low dose dexamethasone. Moreover the high dose group had higher BSI, worse glucose control, higher intubations and deaths in the intubated cohort despite similar severity of illness in either group CLINICAL IMPLICATIONS: High dose dexamethasone may increase susceptibility to HAIs and negatively impact outcomes in COVID-19 associated hypoxemic failure
- |||||||||| sildenafil / Generic mfg., hydrocortisone / Generic mfg.
AN ADRENOCORTICAL ADENOMA HIDING BEHIND THE DIAGNOSIS OF PULMONARY HYPERTENSION (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1994;
She was started on sildenafil 20mg TID...She was optimized for surgery with hydrocortisone for adrenal suppression... While endocrinopathies are commonly associated with PH, cortisol secreting adrenal masses are rarely discussed as an etiology for triggering or worsening PH.
- |||||||||| Comirnaty (tozinameran) / Pfizer, Fosun Pharma, BioNTech
NOT THE VACCINE, BUT ANAPHYLAXIS TO THE COVID-19 VIRUS ITSELF (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1990;
SARS-CoV-2 has clinically presented itself in a multitude of ways across many disciplines. In a patient with a history of urticaria, prolonged anaphylactic symptoms can be triggered by the virus itself.
- |||||||||| Actemra IV (tocilizumab) / Roche, JW Pharma
THE BEAST IN THE BEAUTY BOX (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1940;
She had tested positive for COVID-19 two days prior to presentation and was initiated on remdesivir, tocilizumab, and dexamethasone...Subsequently, she was started on IV levofloxacin and received it for a total of 21 days... This case highlighted the importance of close microbiological surveillance, minimizing occurrence of nosocomial infection and treating atypical organisms.
- |||||||||| A CASE OF FEVER OF UNKNOWN ORIGIN LEADS TO A COMPLEX AND RARE DIAGNOSIS (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1914;
However, it is rarely associated as a solo entity, and should spark investigation for the underlying cause. Though histoplasmosis is common, disseminated infection is rare and typically associated with underlying immunosuppression.
- |||||||||| REGEN-COV (casirivimab/imdevimab) / Regeneron, Roche
TIME TO EXPAND THE USE OF CASIRIVIMAB/IMDEVIMAB MONOCLONAL ANTIBODY THERAPY? A CASE OF COMPASSIONATE USE IN SEVERE COVID-19 PNEUMONIA (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1912;
CASE PRESENTATION: A 76-year-old male with a medical history significant for COPD, Rheumatoid arthritis (treated with hydroxychloroquine and low dose steroids), and monoclonal gammopathy of undetermined significance (MGUS) presented with one week of fever, cough, and fatigue...He was started on Levofloxacin, but he did not meet the criteria for administration of dexamethasone, remdesivir, or monoclonal antibody (mAb) therapy...Our patient received dexamethasone, remdesivir, tocilizumab, and convalescent plasma as part of conventional COVID-19 treatment with continued worsening of COVID-19 pneumonia. Hence, physicians and FDA should consider expanding the use of REGEN-COV mAB therapy to immunosuppressed patients with rapidly worsening COVID-19 pneumonia in adjunct to conventional COVID-19 treatment.
- |||||||||| dexamethasone / Generic mfg.
AN UNUSUAL CASE OF COVID-19 COMPLICATED BY POSSIBLE ACUTE EOSINOPHILIC PNEUMONIA (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1907;
AEP is an uncommon cause of respiratory failure that should be considered in patients with unexplained worsening respiratory status and evidence of eosinophilia. Bronchoscopy with bronchoalveolar lavage should be considered early, even in the setting of COVID-19 in patients without risk factors who develop severe disease.
- |||||||||| Decadron (dexamethasone) / Merck (MSD), Actemra IV (tocilizumab) / Roche, JW Pharma
A CASE OF COVID-19-ASSOCIATED PULMONARY ASPERGILLOSIS (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1906;
The prognosis is poor. Early detection and treatment in clinically deteriorated patients are warranted.
- |||||||||| dexamethasone / Generic mfg., itraconazole / Generic mfg., voriconazole / Generic mfg.
AN UNCOMMON INFECTIOUS IMPOSTER OF LUNG CANCER: A CASE OF ASPERGILLUS NODULES (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1896;
Serological diagnosis is challenging as commonly used serum assays may be negative. The diagnosis is made from a pathologic specimen from surgical resection or trans-bronchial tissue.
- |||||||||| prednisone / Generic mfg., methylprednisolone sodium succinate / Generic mfg.
THE OXYMIZER PENDANT: AN UNDERUTILIZED OXYGEN-DELIVERY DEVICE (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1893;
The Oxymizer pendant is an underutilized, less conventional oxygen nasal cannula system. We present this case to highlight its use to reduce the oxygen flow requirement for those with high oxygen flow rates and to raise awareness about this device.
- |||||||||| dexamethasone / Generic mfg., vancomycin / Generic mfg., warfarin / Generic mfg.
COVID-19 AS A CONFOUNDER IN A CASE OF HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1882;
Physicians should always have it as a differential diagnosis in patients with severe inflammatory states and elevated ferritins to avoid anchoring bias. If suspicion is high based on clinical evaluation and scores, treatment should not be delayed.
- |||||||||| remdesivir / Generic mfg., dexamethasone / Generic mfg.
TB REACTIVATION FOLLOWING COVID-19 INFECTION (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1863;
In this case, the patient had multiple risk factors, but certainly a diagnosis of COVID-19 could weaken the immune system allowing for the reactivation of LTBI. This association will require more research to solidify.
- |||||||||| Actemra IV (tocilizumab) / Roche, JW Pharma
POST-COVID-19 EOSINOPHILIC PNEUMONIA (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1862;
CASE PRESENTATION: Case 1: A 73-year-old gentleman with underlying asymptomatic rheumatoid arthritis (RA), was admitted with COVID pneumonia for which he received tocilizumab, remdesivir, and 12 days of dexamethasone...Despite receiving Furosemide, Vancomycin, and Ceftazidime, he required high-flow nasal cannula oxygenation (HFNC)...Intravenous Levofloxacin and Vancomycin resulted in no clinical improvement...Both patients were started on Prednisone with a prolonged taper... Pulmonary eosinophilic pneumonia is a complication of post-COVID-ILD and can be successfully managed with steroids.
- |||||||||| Actemra IV (tocilizumab) / Roche, JW Pharma
POST-COVID-19 ASPERGILLOSIS (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1861;
Recognizing fungal etiology early on is important in Covid-19 patients as mortality is high and appropriate intervention can reduce morbidity and mortality. Some patient may eventually require lung resection.
- |||||||||| ivermectin oral / Generic mfg.
LUNG CAVITY: A RARE FINDING IN COVID-19 (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1860;
The lung cavity in a COVID patient is an under-recognized entity. This case report highlights the need for further studies to determine the cause of cavitation, which could be related to COVID infection or its treatment.
- |||||||||| Olumiant (baricitinib) / Incyte, Eli Lilly
LIVER ABSCESS DEVELOPMENT IN THE POSTACUTE COVID-19 PHASE (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1859;
Our case is unique and underlines the importance of having a high index of suspicion and monitoring for "occult infections,” such as liver abscesses in the COVID-19 recovery phase, even in those without prior GI medical history and with non-specific signs and symptoms. Further elucidation of the cause of liver injury and abscess formation are warranted; however, early identification and treatment can reduce morbidity and mortality.
- |||||||||| dexamethasone / Generic mfg.
HUMAN RHINOVIRUS INFECTION CAUSING ARDS IN AN IMMUNOCOMPETENT HOST (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1839;
The medical community, in large, thinks of the Rhinovirus as a relatively benign disease process. Though this may be the case in most patients, even immunocompetent individuals can suffer from serious complications of the virus.
- |||||||||| Kevzara (sarilumab) / Asahi Kasei, Regeneron, Sanofi
WHEN NOTHING HELPS: A RARE CASE OF COVID-19 EMPYEMA IN A YOUNG HEALTHY MALE (Convention Center Exhibit Hall: Poster Area) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1832;
He was discharged from the hospital on 2 liters of supplemental oxygen two days ago after undergoing treatment for COVID-19 pneumonia with dexamethasone and remdesivir...Due to high oxygen requirements and CRP of 10.5 MG/DL, the patient was started on Sarilumab... Our case indicates that bacterial empyema may complicate COVID-19 pneumonia later in the disease course even in young immune-competent patients, it is unclear if empyema is directly related to the disease process itself r the therapeutic used to treat the COVID 19 infection.
- |||||||||| Actemra IV (tocilizumab) / Roche, JW Pharma
THE ADDED CLINICAL VALUE OF TOCILIZUMAB IN TREATING ADULTS HOSPITALIZED WITH COVID-19: A RETROSPECTIVE COHORT STUDY (Convention Center 106A) - Aug 16, 2022 - Abstract #CHEST2022CHEST_1799;
TCZ was associated with significantly lower mortality rates and shorter IMV and ICU hospitalization durations in hospitalized COVID-19 patients with hypoxia and systemic inflammation. CLINICAL IMPLICATIONS: Administration of TCZ in hospitalized hypoxic COVID-19 patients showed clinical benefits regardless of the respiratory support extent and were additional to the benefits of Remdesivir and systemic corticosteroids.
- |||||||||| dexamethasone / Generic mfg.
Trial completion, Enrollment change, Trial completion date: Dexamethasone and Functional Outcome After TKA (clinicaltrials.gov) - Aug 16, 2022
P4, N=162, Completed,
Phase classification: P4 --> P3 Enrolling by invitation --> Completed | N=252 --> 162 | Trial completion date: Dec 2022 --> Jun 2022
- |||||||||| Integrilin (eptifibatide) / Takeda
Management Of Uvula Hematoma Following Embolization Of Intracranial Aneurysm (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_5041;
She was given topical tranexamic acid to stop the bleeding, intravenous dexamethasone, and local anesthetic spray. Following resolution of the hematoma, she was discharged home on oral antiplatelet therapy.
- |||||||||| Bridion (sugammadex) / Merck (MSD)
Videolaparoscopic Cholecystectomy In A Previous Pneumectomized Patient: Case Report (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_5036;
Intermittent hyperinflation and intravenous methylprednisolone 125mg were performed, as instructed by a pulmonologist. Surgery and extubation uneventful, after neuromuscular block reversal with sugammadex accompanied by TOF, without postoperative complications or other complaints.
- |||||||||| Berinert (C1 esterase inhibitor (human) IV) / CSL Behring
Idiopathic Angioedema After Reverse Total Shoulder Arthroplasty: A Case Report (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_5026;
Progression of symptoms were successfully prevented after treatment with epinephrine, hydrocortisone, Berinert (C1 esterase inhibitor), diphenhydramine, albuterol, humidified oxygen, and esmolol. The patient was carefully monitored in the recovery period for recurrent episodes of angioedema, and was discharged after three days of continued improvement.
- |||||||||| dexamethasone / Generic mfg., epinephrine / Generic mfg.
A Conservative Approach To Post-extubation Stridor (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_4951;
The patient had complete resolution of the stridor overnight and the heliox was discontinued. He remained extubated and was discharged on hospital day 8.
- |||||||||| Decadron (dexamethasone) / Merck (MSD)
Acute Dystonic Reaction In The Postoperative Period (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_4392;
After being given an additional 25 mg of Diphenhydramine without resolve; she was given Benztropine, after which her symptoms resolved completely without reoccurrence. I plan to discuss the definition and diagnosis of acute dystonic reaction as well as the anesthetic implications and treatment.
- |||||||||| Perioperative Anaphylaxis: Simple To Complicated! (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_4013;
Diphenhydramine, famotidine, and hydrocortisone were also administered...She was weaned off ventilator next day. Serum tryptase level was found elevated to 34.6 ug/L and patient was scheduled for allergy testing as an outpatient.
- |||||||||| hydrocortisone / Generic mfg.
Pregnancy Complicated By Preeclampsia With Severe Features And Adrenal Insufficiency (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_3976;
Stress dose hydrocortisone was administered following a presumptive diagnosis of adrenal insufficiency by nephrology and endocrinology consultations. The patient subsequently underwent an emergent Cesarean section under epidural anesthesia with an arterial line for close blood pressure and electrolyte monitoring.
- |||||||||| dexamethasone / Generic mfg., ropivacaine / Generic mfg.
Effectiveness Of Erector Spinae Plane Nerve Block Without Catheter Placement (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2996;
The patient reported 28 hours of post-operative analgesia compared to 72 hours of analgesia with catheter placement. In this case report, we show that while longer analgesia is obtained using catheter placement, adequate analgesia is still possible with a single injection.
- |||||||||| dexamethasone / Generic mfg.
Pink Urine Propagated By Propofol Infusion (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2975;
Intraoperatively, propofol and sufentanil infusions were used with minimal volatile anesthetic to allow for neuromonitoring. Near the end of the case, he developed pink urine syndrome secondary to propofol infusion.
- |||||||||| Adcetris (brentuximab vedotin) / Seagen, Takeda, Cosentyx (secukinumab) / Novartis
Complications Of New Hodgkin Lymphoma And Secondary Hemophagocytic Lymphohistiocytosis In A Patient With Sapho Syndrome (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2833;
A 39 y.o. man with history of SAPHO syndrome (on secukinumab), hidradenitis suppurativa, and recent hospitalization for septic shock presented with encephalopathy and a painful gluteal lesion...He was started on dexamethasone, etoposide, and brentuximab...His course was further c/b intractable seizures, tumor lysis syndrome, AKI, recurrent sepsis, refractory thrombocytopenia, and ARDS. When he developed septic shock and worsening ARDS, the patient was made DNR.
- |||||||||| methylprednisolone acetate / Generic mfg.
Transnasal Sphenopalatine Block For Migraine Management During Pregnancy (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2531;
We treated her with bilateral transnasal SBP and right greater occipital block with bupivacaine on her initial visit with significant relief on her symptom. During the subsequent visit, we treated her with right greater and lesser occipital blocks based on her headache pattern with depo-medrol and bupivacaine in addition to the bilateral SBP.
- |||||||||| Sphenopalatine Ganglion Block: A Novel Therapy For Post-maxillectomy Facial Pain (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_2527;
Serial fluoroscopically guided SPGBs were performed using 2% lidocaine and 5 mg dexamethasone...Pain improvement was maintained at 1-year follow-up. We postulate that pain relief is due to blockade of maxillary derived sensory fibers, petrosal nerve and stellate ganglion derived sympathetic fibers that contribute to the pterygopalatine ganglion.
- |||||||||| remifentanil / Generic mfg., dexamethasone / Generic mfg., paracetamol / Generic mfg.
Anesthesia In Phelan-McDermid Syndrome (Hall C) - Aug 15, 2022 - Abstract #ASA2022ASA_1913;
Maintenance: propofol 250 mcg/kg/min, remifentanil 0.25 mcg/kg/min, dexamethasone 0.25 mg/kg, acetaminophen 15 mg/kg.PMS patients may be predisposed to difficult airway, increased pain tolerance, and decreased perspiration resulting in tendency to overheat. 1 1.Phelan,Katy,and HE3366702McDermid."The-22q13.3-deletion-syndrome(Phelan-McDermid syndrome)." Molecular syndromology 2.3-5(2011):186-201
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