- |||||||||| Uncommon Dermatoses of Pregnancy (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4363;
The patient received local therapy with clobetasol cream, tablet chlorpheniramine p.o. with marked improvement of her skin lesions, the patient was followed up regularly. Management of dermatologic diseases during pregnancy might be challenging as it requires special attention to both mother and fetus.
- |||||||||| Pandel (hydrocortisone probutate) / Novartis
Heroic actions of dermatologists during the Holocaust (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4345;
Management of dermatologic diseases during pregnancy might be challenging as it requires special attention to both mother and fetus. A recent study identified five non- Jewish dermatologists
- |||||||||| triamcinolone acetonide / Generic mfg.
Cutaneous Rosai-Dorfman disease at the SARS-CoV2 vaccine injection site (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4321;
We present a case of cutaneous RDD at the SARS-CoV-2 vaccine injection site. Clinicians should consider RDD within the spectrum of rare cutaneous manifestations associated with SARS-CoV-2 infection and its vaccines.
- |||||||||| Jakafi (ruxolitinib) / Incyte, Opzelura (ruxolitinib cream) / Incyte
Pyoderma gangrenosum with unusual localization (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4261;
The patient reported long-lasting medical history of chronic myeloproliferative neoplasia, controlled with Ruxolitinib for 3 years...A systemic therapy with high-dose dexamethasone and antihistamines was initiated, associated with topical treatment with antibiotic ointment and epithelial cream... This case is reported to emphasize that PG is one of the differential diagnoses in those genital and inguinal ulcers in which no demonstrable cause is identified.
- |||||||||| Jak Inhibitor in a Refractory Case of penile HS (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4253;
Due to complications and poor control of HS in this patient, he will now be started on Tofacitinib (Jak inhibitor) in addition to a TNF alpha inhibitor for greater benefit. Additionally, cyclosporine was used as an off-label treatment to manage this patient
- |||||||||| Kineret (anakinra) / SOBI, Humira (adalimumab) / AbbVie
Non-classifiable pyoderma gangrenosum-associated autoinflammatory syndrome: successful treatment with anti-IL-1 therapy (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4224;
Progressive worsening was observed, with large cutaneous aseptic abscesses requiring surgical drainage and maintained therapy with oral prednisolone in a dose above 20 mg per day... Patients may present with a clinical picture suggestive of PGAAIS while not falling into the existing categories, and IL-1 presents itself as a potential therapy, even in these non-classifiable cases.
- |||||||||| tacrolimus topical / Generic mfg., hydrocortisone / Generic mfg.
Pediatric lichen Planus Pigmentosus: Rare melanoderma (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4186;
In the presence of dark hyperpigmentation of the skin, a biopsy can help identify LPP. Clinicians should be aware that LPP can follow four patterns: common, inverse, palmoplantar, and linear.
- |||||||||| hydrocortisone / Generic mfg.
Psoriasis of the lips: an unusual localization (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4111;
Clinicians should consider psoriasis in lip lesions, especially without clear predisposing factors. Early recognition and appropriate management are crucial for favorable outcomes.
- |||||||||| cetirizine oral / Generic mfg., mometasone furoate / Generic mfg.
Dermanyssus gallinae dermatitis in a young Italian woman: a case report (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_4011;
Patient was started with cetirizine 10 mg once a day plus mometasone furoate cream for 10 days in order to alleviate itching and inflammation. This case highlights the importance of considering environmental factors, such as exposure to poultry or feral birds and their associated parasites, in the evaluation of dermatological conditions.
- |||||||||| prednisolone / Generic mfg.
Utility of High-frequency ultrasonography in the diagnosis of peripheral nerve involvement in leprosy (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3994;
Considering the slow and incomplete recovery of nerve dysfunction in leprosy, it is important to diagnose nerve pathologies early in the course of the disease to preserve nerve function. HFUS is found to be a simple, non- invasive accurate, reproducible, and objective method to diagnose nerve involvement in Leprosy.
- |||||||||| dexamethasone / Generic mfg., doxycycline / Generic mfg., promethazine / Generic mfg.
onchocerciasis : forgotten but not quite gone (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3962;
He denied the use of traditional medication but reports self-medication on drugs he believed to relieve his itch, especially dexamethasone...The patient was started on ivermectin 1.2mg stat, doxycycline 100mg OD, and betamethasone ointment with promethazine 25mg nocte... To avert missed diagnoses, it
- |||||||||| methotrexate / Generic mfg.
Successful Treatment of Methotrexate As Steroid-Sparing Agent for Chronic Erythema Nodosum Leprosum (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3855;
The patient had a history of treatment with prolonged methylprednisolone tablets and a combination of rifampicin, ofloxacin, and minocycline (ROM) for 12 weeks...This treatment regimen has fewer adverse effects, widely available, and affordable in comparison to other agents used to manage ENL such as cyclosporin, pentoxifylline, azathioprine, and mycophenolate mofetil. Methotrexate as a steroid-sparing agent may be an effective alternative treatment regimen in the case of chronic ENL reaction.
- |||||||||| triamcinolone acetonide / Generic mfg., minoxidil / Generic mfg.
Perinevoid Alopecia: A Case Report of a Rare Entity (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3827;
Methotrexate as a steroid-sparing agent may be an effective alternative treatment regimen in the case of chronic ENL reaction. Due to the patient
- |||||||||| Herceptin (trastuzumab) / Roche
Lichen planopilaris induced by chemotherapy for breast cancer (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3814;
Most chemotherapeutic agents cause temporary hair loss, yet several cases of chemotherapy-induced LPP have been reported in the literature, often in breast cancer patients. Despite its relatively rare occurrence, there is a need to inform the patients about the possible risk of permanent hair loss and in case of such complications, multidisciplinary support, including dermatological treatments, should be provided.
- |||||||||| Olumiant (baricitinib) / Eli Lilly
Nailing It: Baricitinib's Unexpected Triumph in Alopecia Areata (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3800;
This finding raises questions about therapeutic management in patients with significant nail involvement who respond positively to the drug but show no signs of hair regrowth. Is it prudent to continue treatment beyond 9 months, or should we consider this response as therapeutic failure and discontinue the medication?
- |||||||||| prednisolone / Generic mfg., acitretin / Generic mfg., azathioprine / Generic mfg.
More Than Meets The Eye (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3625;
Oral mucosal manifestations of lipoid proteinosis may resemble several other cutaneous and systemic diseases. Histopathological examination as well as genetic analysis and counselling should be carried out.
- |||||||||| trimethoprim/sulfamethoxazole / Generic mfg., hydrocortisone / Generic mfg.
Chronic Granulomatous Disease in a Filipino Patient: A Case Report (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3614;
Given the rare occurrence of this disease, makes this an important emerging field of study. This case report will add to the minimal data we have about CGD, particularly in the Philippines.
- |||||||||| hydroxychloroquine / Generic mfg., prednisolone / Generic mfg.
Subcutaneous panniculitis-like T-cell lymphoma and lupus erythematosus profundus: a diagnostic dilemma (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3369;
In a patient presenting with SPTCL, an associated autoimmune disease should also always be considered and appropriate serology undertaken. When LEP is the dominant histological appearance, the pathologist should look carefully for tiny foci suggestive of SPTCL, particularly as the latter disease may be associated with subsequent development of HLH.
- |||||||||| prednisone / Generic mfg., methylprednisolone sodium succinate / Generic mfg.
Cutaneous leukocytoclastic vasculitis: A case report with onset during pregnancy. (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3362;
Limited data exist regarding pregnancies in the context of systemic vasculitides. Published cases of vasculitis occurring during pregnancy are scarce, suggesting a minimal role of pregnancy in triggering or exacerbating these conditions.
- |||||||||| dexamethasone / Generic mfg.
A not so Sweet outcome: highlighting a rare histological variant with prognostic value (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3361;
The challenge in our case was to differentiate between the two entities given the two-sided context. While the histiocytoid variant of SS is rarely associated with IBD, it conversely requires further hematological follow-up so as not to miss the development of MDS.
- |||||||||| Mucocutaneous manifestations as a clue for reactive and disabling arthritis (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3349;
This case highlights the importance of skin inspection facing a case of arthritis, for the diagnosis of a reactive disorder. In our case, keratoderma blenorragica, circinate balanitis and nail dystrophy were the cardinal features.
- |||||||||| Humira (adalimumab) / AbbVie
Case Series of Rare Metastatic Crohn (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3333;
MCD, characterized by non-caseating granulomas in extraintestinal sites, with facial or breast involvement is exceptional. Since clinical presentation of MCD varies, it may lead to under-recognition and misdiagnosis.
- |||||||||| Rituxan (rituximab) / Roche
Cutaneous Manifestation Predictive of Progression and Poor Prognosis in Non-Hodgkin Lymphoma: A Case Report (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3308;
She had been undergoing chemotherapy for B-cell large cell lymphoma exclusively involving the lymph nodes, having completed sessions with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone, with the last session less than 6 months ago...It was then decided to restart treatment with dexamethasone, cytarabine, and cisplatin...There are several reports in the literature whit skin involvement by lymphoma. Most of these cases however describe the skin as the disease
- |||||||||| Lynparza (olaparib) / Merck (MSD), AstraZeneca
A rare case of erythema gyratum repens in ovarian cancer: a case report (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3245;
To the best of our knowledge, our report is the first documented case of EGR as a paraneoplastic eruption of ovarian carcinoma. EGR histology is often non-specific, therefore it is crucial that suspected EGR must be diagnosed in correlation with clinical examination.
- |||||||||| triamcinolone acetonide / Generic mfg.
Contact cryotherapy and triamcinolone acetonide as treatment for auricular keloids (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3222;
We introduce a novel technique combining surgery, contact cryotherapy, and intralesional corticosteroid therapy for piercing-related keloid treatment. Despite the limited patient cohort and short follow-up period, we propose this approach as a feasible treatment option for keloids, utilizing materials commonly available in healthcare centers.
- |||||||||| Cutaneous Anaplastic Large Cell Lymphoma in a Child (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_3112;
Clinically, ALCL can manifest as localized (primary) skin disease or widespread systemic disease. Both types, however, share a similar histology, characterized by cohesive sheets of large lymphoid cells expressing the Ki-1 molecule (CD30) .
- |||||||||| triamcinolone acetonide / Generic mfg., 5-fluorouracil / Generic mfg.
Recalcitrant foreign body granuloma in the neck following poly-L-lactic acid injection (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2885;
Intralesional corticosteroids, hyaluronidase, antibiotics, or surgical extraction were the last resorts that resolved the majority of the described cases. The histological findings may point to the function of immunity since the nodules recurred after surgical removal, despite the clearance of nodules on ultrasound following their surgical removal.
- |||||||||| triamcinolone acetonide / Generic mfg., betamethasone dipropionate / Generic mfg.
Thermal burn injury keloid scars treated with intralesional steroids and pulsed-dye laser therapy (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2827;
The mechanism of corticosteroid action is related to the suppression of collagen synthesis by decreased gene expression within the scar. Advances in laser technology have made laser therapy one of the most advantageous treatments of scars, targeting the vascular component, but also through collagen fibers remodeling.
- |||||||||| budesonide / Generic mfg.
Allergic contact dermatitis to topically applied glucocorticosteroids. (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2769;
The collected data has significant implications from a public health perspective. Continuous upading of data regarding the prevalence of drug sensitizations, including glucocorticorteroids, is justified due to their impact on the selection of futher diagnostics and treatment of patients, especially in the era of an aging society.
- |||||||||| Dupixent (dupilumab) / Sanofi, Regeneron
Successful Treatment Of Recalcitrant Bullous Pemphigoid In A 73 Year Old Female With Subcutaneous Dupilumab (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2673;
We present a case of a 73-year-old lady who had significant symptom burden secondary to BP for over two years refractory to systemic therapy who had complete resolution of pruritis and blistering with dupilumab. There is growing evidence base to suggest safe and efficacious use of this novel therapy for BP patients with significant symptom burden who are unsuitable for common systemic agents.
- |||||||||| generalized lichen planus pigmentosus and a new management approach (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2671;
There is growing evidence base to suggest safe and efficacious use of this novel therapy for BP patients with significant symptom burden who are unsuitable for common systemic agents. She had Hashimoto hypothyroidism, which was managed with levothyroxine...She had undergone two skin biopsies, both of which indicated atypical findings of Lichen Planus pigmentosus and she was prescribed oral prednisolone (20mg daily); but no significant improvements were detected in her lesions after six months...To our knowledge, this is the first report in which tofacitinib dramatically improves the generalized LPP with palmar involvement.
- |||||||||| Dupixent (dupilumab) / Sanofi, Regeneron, Opdivo (nivolumab) / BMS, Xolair (omalizumab) / Roche, Novartis
Omalizumab and dupilumab (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2629;
The patient was initially treated with oral prednisolone 0.5mg/kg, doxycycline 100mg twice daily and topical clobetasol propionate...Despite treatment with oral prednisolone, mycophenolate mofetil, IVIg and rituximab her condition continued to progress... Given the many inherent risks and complications associated with immunosuppression in this patient group, targeted therapies such as dupilumab and omalizumab may provide a safe and efficacious option, either as single agents or in severe refractory cases such as this one, as combination therapy.
- |||||||||| methylprednisolone sodium succinate / Generic mfg.
childhood scleromyositis : a case report (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2613;
She received a bolus of Solu-Medrol for 3 days followed by general corticosteroid therapy at a dose of 1 mg/kg/day... Our case illustrates a rare presentation of pediatric scleromyositis with a particular severe clinical presentation.
- |||||||||| dexamethasone / Generic mfg., doxycycline / Generic mfg.
Bullous pemphigoid in association with urothelial carcinoma (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2597;
In some cases, BP may occur before or after the diagnosis of bladder cancer. Some studies suggest that common genetic and immunological factors may play a role in their pathogenesis and may be involved in the development of both conditions.
- |||||||||| dexamethasone / Generic mfg.
Glutathione induced relapse of pemphigus vulgaris (Poster Area) - Aug 5, 2024 - Abstract #EADV2024EADV_2544;
Thiol drugs have sulfhydryl (-SH) group in their chemical structure and are probably the better studied group of drugs in the pathogenesis of drug-induced pemphigus. Glutathione and vitamin C infusions are currently widely administered as a cocktail with anti-oxidative and reparative potential applied both in healthy individuals and patients suffering from different diseases.
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