- |||||||||| triamcinolone acetonide topical / Generic mfg.
Trial completion date, Trial primary completion date: Fractional Ablative Laser Treatment for Skin Grafts (clinicaltrials.gov) - Jul 5, 2023
P=N/A, N=29, Recruiting,
Trial completion date: Apr 2025 --> Jan 2034 | Trial primary completion date: Apr 2024 --> Sep 2024 Trial completion date: Jun 2023 --> Sep 2023 | Trial primary completion date: Jun 2023 --> Sep 2023
- |||||||||| Ninlaro (ixazomib) / Takeda
Trial completion date, Trial primary completion date: Ixazomib Maintenance Study in Patients With AL Amyloidosis (clinicaltrials.gov) - Jul 5, 2023
P2, N=47, Recruiting,
Trial completion date: Jun 2023 --> Sep 2023 | Trial primary completion date: Jun 2023 --> Sep 2023 Trial completion date: Aug 2023 --> Aug 2026 | Trial primary completion date: Aug 2023 --> Aug 2026
- |||||||||| Darzalex (daratumumab) / J&J
Trial completion date, Trial primary completion date: A Study of Daratumumab in Patients With Newly Diagnosed Multiple Myeloma (clinicaltrials.gov) - Jul 5, 2023
P2, N=75, Active, not recruiting,
Trial completion date: Aug 2023 --> Aug 2026 | Trial primary completion date: Aug 2023 --> Aug 2026 Trial completion date: Sep 2023 --> Sep 2024 | Trial primary completion date: Sep 2023 --> Sep 2024
- |||||||||| Decadron (dexamethasone) / Merck (MSD)
Trial completion date, Metastases: Dexamethasone for Symptom Burden in Advanced Cancer Patients (clinicaltrials.gov) - Jul 5, 2023
P2, N=132, Active, not recruiting,
Trial completion date: Sep 2023 --> Sep 2024 | Trial primary completion date: Sep 2023 --> Sep 2024 Trial completion date: Feb 2023 --> Feb 2028
- |||||||||| dexamethasone / Generic mfg.
Journal: Cushing disease in pediatrics: an update. (Pubmed Central) - Jul 4, 2023
Endogenous hypercortisolism should be established after exogenous CS has been ruled out based on 24-hour urinary free cortisol, midnight serum or salivary cortisol, and dexamethasone suppression test; after that, ACTH dependence should be established...Its rarity in pediatric patients has led physicians to have limited experience in its management. The objective of this narrative review is to summarize the current knowledge about the pathophysiology, diagnosis, and treatment of CD in the pediatric population.
- |||||||||| dexamethasone / Generic mfg., indomethacin / Generic mfg.
Journal: The ribosome-inactivating proteins MAP30 and Momordin inhibit SARS-CoV-2. (Pubmed Central) - Jul 3, 2023
From a structural comparison of the two proteins, one can explain their similar activities despite differences in both their active-sites and ribosome-binding regions. We also note points on the viral genome for potential inhibition by these proteins.
- |||||||||| methylprednisolone acetate / Generic mfg.
Journal: Comparing the Efficacy of Intra-articular Platelet-Rich Plasma and Corticosteroid Injections in the Management of Frozen Shoulder: A Randomized Controlled Trial. (Pubmed Central) - Jul 3, 2023
Methods In this prospective, randomized study, 68 patients who met the inclusion criteria were enrolled and randomized using a computer-generated table into two groups: Group 1 (IA PRP) received 4 ml PRP, and Group 2 (IA CS) received 2 ml (80 mg) of methylprednisolone acetate mixed with 2 ml normal saline (for a total of 4 ml) as a CS injection in the IA area of the shoulder...Platelet-rich plasma can be used as a treatment modality for better outcomes, particularly when the patient is contraindicated or refuses CS treatment. Further research is needed to evaluate the efficacy of these treatment modalities at different stages of FS and explore the potential benefits of ultrasound-guided injections.
- |||||||||| hydrocortisone / Generic mfg.
Preclinical, Journal: Anti-fatigue effect of Lubian on kidney Yin deficiency and kidney Yang deficiency mice and mechanism based on PI3K-Akt pathway (Pubmed Central) - Jul 3, 2023
The kidney Yin deficiency model and kidney Yang deficiency model were prepared by daily regular oral administration of dexamethasone acetate and hydrocortisone, respectively, and meanwhile, corresponding drugs were provided...Compared with the kidney Yin deficiency model group, the kidney Yin deficiency-Lubian treatment groups showed increased body weight(P<0.01), relieved symptoms of Yin deficiency, increased content of cGMP(P<0.01), decreased cAMP/cGMP(P<0.01), prolonged exhausted swimming time(P<0.01), decreased LD(P<0.01), decreased BUN content(P<0.01), increased liver glycogen content(P<0.01), and increased protein expression of PI3K(P<0.05) and Akt in the liver(P<0.05). To sum up, Lubian can regulate Yin deficiency and Yang deficiency and increase glycogen synthesis by affecting the PI3K-Akt pathway, thereby exerting an anti-fatigue role.
- |||||||||| dexamethasone / Generic mfg., clarithromycin / Generic mfg., pomalidomide / Generic mfg.
Trial completion date, Trial primary completion date: Autologous Stem Cell Transplant With Pomalidomide (CC-4047 (clinicaltrials.gov) - Jul 3, 2023
P2, N=23, Active, not recruiting,
Trial completion date: Mar 2023 --> Oct 2023 Trial completion date: Dec 2023 --> Dec 2024 | Trial primary completion date: Dec 2023 --> Dec 2024
- |||||||||| dexamethasone / Generic mfg., carfilzomib / Generic mfg., pomalidomide / Generic mfg.
Trial completion, Trial completion date: Phase I/II Study of Carfilzomib, Pomalidomide and Dexamethasone in Relapsed And/Or Refractory Multiple Myeloma Patients (CPD) (clinicaltrials.gov) - Jul 3, 2023
P1/2, N=57, Completed,
Recruiting --> Active, not recruiting Active, not recruiting --> Completed | Trial completion date: Sep 2022 --> Jan 2023
- |||||||||| triamcinolone acetonide / Generic mfg.
Polydeoxyribonucleotide Improves The Quality Of Skin In Keloid Scars Post Corticosteroid Intralesional Injections () - Jul 3, 2023 - Abstract #WCD2023WCD_7816;
The keloids had been treated with serial triamcinolone acetonide 40mg/ml intralesional injections that showed successful regression...The results include decreasing telangiectasias, hyperpigmentation, erythema, and preventing recurrence. KEY MASSAGE: Polydeoxyribonucleotide/PDRN can improve quality of keloid scars by decreasing telangiectasias, hyperpigmentation, erythema, and preventing recurrence
- |||||||||| prednisolone / Generic mfg.
Successful treatment of skin-limited crystalglobulinemia with oral corticosteroids and review of the literature (Level 6 - Hall 602) - Jul 3, 2023 - Abstract #WCD2023WCD_7784;
She was initiated on a course of oral prednisolone (1 mg/kg/day)...We hypothesize that skin-limited crystalglobulinemia in the setting of MGUS may confer a better prognosis compared to MM, allowing the avoidance of toxic systemic chemotherapy. In these patients, we propose a trial of corticosteroid therapy with serial monitoring for progression of disease
- |||||||||| methylprednisolone oral / Generic mfg.
Successful Treatment Of Beh () - Jul 3, 2023 - Abstract #WCD2023WCD_7783;
The combination of topical sucralfate suspension alternating with wet saline gauze as dressing gradually rehabilitated the ulcerations on oral mucosa and external genitalia. KEY MESSAGES: Beh
- |||||||||| methylprednisolone sodium succinate / Generic mfg.
Large fixed urticarian plate simulating lepromatous leprosy () - Jul 3, 2023 - Abstract #WCD2023WCD_7753;
The etiology of urticaria is as multiple as its clinical presentation. think of chronic urticaria in front of any itchy edematous cupboard.
- |||||||||| prednisolone / Generic mfg., thalidomide / Generic mfg., acyclovir / Generic mfg.
Varied uncommon presentation of Erythema nodosum leprosum: A case series () - Jul 3, 2023 - Abstract #WCD2023WCD_7666;
KEY MESSAGE: All our cases had de-novo presentation of uncommon morphology of ENL and were diagnosed on basis of histopathology. Hence in vesicular and pustular lesions in endemic areas of leprosy, ENL should be kept as differential for early diagnosis and treatment
- |||||||||| albendazole / Generic mfg.
Successfully Cured of Cutaneous Larva Migrans with Oral Albendazole on unsual site: A Case Report () - Jul 3, 2023 - Abstract #WCD2023WCD_7615;
In addition, mometasone furoate 0.1% topically twice daily was applied on the hyperpigmentation and serpiginous erythematous lesions...KEY MESSAGE: CLM is a skin infestation caused by penetration and migration in the epidermis of larvae of nematodes. Oral albendazole has an important role to against infections caused by nematodes and leads to rapid resolution of the lesions confirmed the initial diagnosis of cutaneous larva migrans.
- |||||||||| hydrocortisone / Generic mfg., mefenamic acid / Generic mfg., amoxicillin / Generic mfg.
Management of Chronic Vesicobullous Dermatitis with Secondary Bacterial Infection in Public Primary Health Care in Indonesia () - Jul 3, 2023 - Abstract #WCD2023WCD_7530;
Oral antihistamine (cetirizine) qd and topical corticosteroid (hydrocortisone 1%) bid was then given after secondary infection was resolved. KEY MESSAGE: This case illustrates the importance of thorough history taking, wound debridement and compress before application of topical therapies, and patient compliance in order to achieve successful diagnosis and treatment of skin diseases under the condition of limited resources and medication options available at a public primary health care facility
- |||||||||| dexamethasone / Generic mfg.
Lucio Phenomenon: A Report Of Two Severe Cases From Yogyakarta Indonesia () - Jul 3, 2023 - Abstract #WCD2023WCD_7525;
KEY MESSAGE: This case illustrates the importance of thorough history taking, wound debridement and compress before application of topical therapies, and patient compliance in order to achieve successful diagnosis and treatment of skin diseases under the condition of limited resources and medication options available at a public primary health care facility The patient was given multidrug therapy-multibacillary (MDT-MB) WHO regimen, dexamethasone, ofloxacin, and standard wound care...Later, the patient
- |||||||||| Localised erythema nodosum leprosum () - Jul 3, 2023 - Abstract #WCD2023WCD_7521;
Reports of localised ENL are rare and may not be immediately recognised because it differs markedly from the more common widespread distribution of ENL. The response of this patient to thalidomide which is effective in managing ENL but not T1R supports the diagnosis of localised ENL
- |||||||||| Co existence of primary HIV infection and dress syndrome: A true association or a coincidence? () - Jul 3, 2023 - Abstract #WCD2023WCD_7070;
involving 10 days after the introduction of terbinafine and amoxicillin...the patient Has reseaved a bolus of solumedrol relayed by oral corticosteroid therapy associated with antiretroviral treatment...The physiopathology involves several theories, particularly that of viral reactivation by analogy with the increased frequency of ampicillin toxidermia during Epstein Barr Virus (EBV) infections...However, the problem arises when it is necessary to differentiate in the same patient between a toxidermia and a primary HIV infection with which, it shares the same clinical biology and histology characteristics. In this case, the search for an evocative context is essential, such as taking medication and a regression of symptoms when the incriminated molecule is interrupted as was the case of our patient
- |||||||||| triamcinolone acetonide / Generic mfg., doxycycline / Generic mfg.
A case report of Syphilitic Balanitis of Follmann () - Jul 3, 2023 - Abstract #WCD2023WCD_7056;
Considering the fact that benzathine penicilin was not available in our country at the time of the diagnosis, the patient was treated with oral doxycycline (100 mg twice a day for 14 days), with complete resolution of the genital eruption. KEY MESSAGE: Syphilitic balanitis of Follmann represents a challenge diagnosis that shoud be kept in mind everytime facing a case of non-specific balanitis, especially in patients at risk of sexually transmited infections
- |||||||||| Maxidex (dexamethasone eye drops, suspension) / Novartis
A case of secondary syphilis with panuveitis as a manifestation of ocular syphilis in an HIV-positive patient () - Jul 3, 2023 - Abstract #WCD2023WCD_7055;
He also started to receive once a day antiretroviral (ARV) that consists of efavirenz 600 mg, lamivudine 300 mg, and tenofovir 300 mg...KEY MESSAGE: In HIV positive patients without antiretroviral therapy, Treponema pallidum is more common and has manifestations such as skin rash and ocular syphilis. Treatment using penicillin, ARV and steroid therapy will improve the patient symptoms
- |||||||||| mometasone furoate / Generic mfg.
Linear cutaneous lupus erythematous- an important differential for Blaschkoid dermatoses () - Jul 3, 2023 - Abstract #WCD2023WCD_7030;
She was advised sun protection and started on mometasone furoate 0.1% cream twice daily, with noted improvement after 2 weeks and complete resolution of the linear eruption after 3 months of treatment...We propose that LCLE be regarded as a primary differential in adult patients presenting with unilateral Blaschkoid dermatoses. Topical corticosteroids may be sufficient in the treatment of LCLE
- |||||||||| prednisolone / Generic mfg.
Intralymphatic histiocytosis associated with polymyalgia rheumatica and total hip replacement () - Jul 3, 2023 - Abstract #WCD2023WCD_7027;
In view of the raised inflammatory markers and PMR symptoms oral prednisolone 15mg once daily was started...It presents with isolated asymmetrical plaques, macules or nodules and often presents in patients with underlying rheumatoid arthritis, malignancy, and metal implantation. This is the first case in the literature of ILH associated with PMR and a THR
- |||||||||| methylprednisolone sodium succinate / Generic mfg.
Dermatomyositis presenting as Angioedema: a rare entity () - Jul 3, 2023 - Abstract #WCD2023WCD_7017;
She was administered intravenous Methylprednisolone pulse...Due to the florid clinical course of such patients, immediate treatment and rigorous screening for malignancy is needed. Hence, the possibility of dermatomyositis should be kept in mind in cases of idiopathic angioedema refractory to treatment
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